Prohormone convertase 1/3 and 2 together orchestrate the site-speciifc cleavages of progastrin to release gastrin-34 and gastrin-17

Biochemical Journal

Volumn 415, Issue 1, 2008, Pages 35-43

  Rehfeld, Jens F ^a   Zhu, Xiaorong ^b   Norrbom, Christina ^b   Bundgaard, Jens R ^a   Johnsen, Anders H ^a   Nielsen, John E ^a   Vikesaa, Jonas ^a   Stein, Jeffrey ^b   Dey, Arunangsu ^b   Steiner, Donald F ^b   Friis Hansen, Lennart ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Gastrin; Peptide hormone; Post translational processing; Progastrin; Prohormone convertase

Indexed keywords

AMINES; CHROMATOGRAPHIC ANALYSIS; CONCENTRATION (PROCESS); HORMONES;

GASTRIN; PEPTIDE HORMONE; POST-TRANSLATIONAL PROCESSING; PROGASTRIN; PROHORMONE CONVERTASE;

MICROCOMPUTERS;

ARGININE; GASTRIN; GASTRIN 17; GASTRIN 34; GASTROINTESTINAL HORMONE; HORMONE PRECURSOR; LYSINE; PEPTIDE HORMONE; PROGASTRIN; PROPROTEIN CONVERTASE 1; PROPROTEIN CONVERTASE 2; PROPROTEIN CONVERTASE 5; UNCLASSIFIED DRUG; PROTEIN PRECURSOR; RECOMBINANT PROTEIN;

AMIDATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHROMATOGRAPHY; CONTROLLED STUDY; ENZYME SPECIFICITY; GASTRIN CELL; HORMONE SYNTHESIS; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; CHO CELL; CRICETULUS; HAMSTER; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; MOLECULAR GENETICS; MOUSE MUTANT; SECRETION; STOMACH ANTRUM;

MUS; RATTUS;

AMINO ACID SEQUENCE; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; GASTRIN-SECRETING CELLS; GASTRINS; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; PROPROTEIN CONVERTASE 1; PROPROTEIN CONVERTASE 2; PROPROTEIN CONVERTASE 5; PROTEIN PRECURSORS; PYLORIC ANTRUM; RECOMBINANT PROTEINS;

EID: 53149093995     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20080881     Document Type: Article

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