-
1
-
-
0026721532
-
Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate. Advanced Colorectal Cancer Meta-analysis Project
-
Anonymous
-
Anonymous (1992) Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. Advanced Colorectal Cancer Meta-analysis Project. J Clin Oncol 10:896-903
-
(1992)
J Clin Oncol
, vol.10
, pp. 896-903
-
-
-
2
-
-
0027489763
-
5-Ethynyluracil (776C85): A potent modulator of the pharmacokinetics and antitumor efficacy of 5-fluorouracil
-
DP Baccanari ST Davis VC Knick T Spector 1993 5-Ethynyluracil (776C85): a potent modulator of the pharmacokinetics and antitumor efficacy of 5-fluorouracil Proc Natl Acad Sci U S A 90 11064 11068
-
(1993)
Proc Natl Acad Sci U S a
, vol.90
, pp. 11064-11068
-
-
Baccanari, D.P.1
Davis, S.T.2
Knick, V.C.3
Spector, T.4
-
3
-
-
8244254377
-
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
-
HA Burris 3rd MJ Moore J Andersen MR Green ML Rothenberg MR Modiano MC Cripps RK Portenoy AM Storniolo P Tarassoff R Nelson FA Dorr CD Stephens DD Von Hoff 1997 Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial J Clin Oncol 15 2403 2413
-
(1997)
J Clin Oncol
, vol.15
, pp. 2403-2413
-
-
Burris III, H.A.1
Moore, M.J.2
Andersen, J.3
Green, M.R.4
Rothenberg, M.L.5
Modiano, M.R.6
Cripps, M.C.7
Portenoy, R.K.8
Storniolo, A.M.9
Tarassoff, P.10
Nelson, R.11
Dorr, F.A.12
Stephens, C.D.13
Von Hoff, D.D.14
-
4
-
-
0025815267
-
Lack of efficacy of high-dose leucovorin and fluorouracil in patients with advanced pancreatic adenocarcinoma
-
J Crown ES Casper J Botet P Murray DP Kelsen 1991 Lack of efficacy of high-dose leucovorin and fluorouracil in patients with advanced pancreatic adenocarcinoma J Clin Oncol 9 1682 1686
-
(1991)
J Clin Oncol
, vol.9
, pp. 1682-1686
-
-
Crown, J.1
Casper, E.S.2
Botet, J.3
Murray, P.4
Kelsen, D.P.5
-
5
-
-
0025360261
-
A phase III trial on the therapy of advanced pancreatic carcinoma. Evaluations of the Mallinson regimen and combined 5-fluorouracil, doxorubicin, and cisplatin
-
S Cullinan CG Moertel HS Wieand AJ Schutt JE Krook JF Foley BD Norris CG Kardinal LK Tschetter JF Barlow 1990 A phase III trial on the therapy of advanced pancreatic carcinoma. Evaluations of the Mallinson regimen and combined 5-fluorouracil, doxorubicin, and cisplatin Cancer 65 2207 2212
-
(1990)
Cancer
, vol.65
, pp. 2207-2212
-
-
Cullinan, S.1
Moertel, C.G.2
Wieand, H.S.3
Schutt, A.J.4
Krook, J.E.5
Foley, J.F.6
Norris, B.D.7
Kardinal, C.G.8
Tschetter, L.K.9
Barlow, J.F.10
-
6
-
-
0031019918
-
Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: A French intergroup study
-
A de Gramont JF Bosset C Milan P Rougier O Bouche PL Etienne F Morvan C Louvet T Guillot E Francois L Bedenne 1997 Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: a French intergroup study J Clin Oncol 15 808 815
-
(1997)
J Clin Oncol
, vol.15
, pp. 808-815
-
-
De Gramont, A.1
Bosset, J.F.2
Milan, C.3
Rougier, P.4
Bouche, O.5
Etienne, P.L.6
Morvan, F.7
Louvet, C.8
Guillot, T.9
Francois, E.10
Bedenne, L.11
-
7
-
-
0025841867
-
Fluorouracil and high-dose leucovorin in previously untreated patients with advanced adenocarcinoma of the pancreas: Results of a phase II trial
-
JA DeCaprio RJ Mayer R Gonin SG Arbuck 1991 Fluorouracil and high-dose leucovorin in previously untreated patients with advanced adenocarcinoma of the pancreas: results of a phase II trial J Clin Oncol 9 2128 2133
-
(1991)
J Clin Oncol
, vol.9
, pp. 2128-2133
-
-
Decaprio, J.A.1
Mayer, R.J.2
Gonin, R.3
Arbuck, S.G.4
-
8
-
-
0028078635
-
Quality of life during chemotherapy in patients with symptomatic advanced colorectal cancer. the Nordic Gastrointestinal Tumor Adjuvant Therapy Group
-
B Glimelius K Hoffman W Graf L Pahlman PO Sjoden 1994 Quality of life during chemotherapy in patients with symptomatic advanced colorectal cancer. The Nordic Gastrointestinal Tumor Adjuvant Therapy Group Cancer 73 556 562
-
(1994)
Cancer
, vol.73
, pp. 556-562
-
-
Glimelius, B.1
Hoffman, K.2
Graf, W.3
Pahlman, L.4
Sjoden, P.O.5
-
9
-
-
0023880296
-
Continuous 5-fluorouracil (5FU) infusion in carcinoma of the pancreas: A phase II study
-
R Hansen E Quebbeman P Ritch C Chitambar T Anderson 1988 Continuous 5-fluorouracil (5FU) infusion in carcinoma of the pancreas: a phase II study Am J Med Sci 295 91 93
-
(1988)
Am J Med Sci
, vol.295
, pp. 91-93
-
-
Hansen, R.1
Quebbeman, E.2
Ritch, P.3
Chitambar, C.4
Anderson, T.5
-
10
-
-
0036835318
-
High response rates in patients with pancreatic cancer using the novel oral fluoropyrimidine S-1
-
K Hayashi T Imaizumi K Uchida H Kuramochi K Takasaki 2002 High response rates in patients with pancreatic cancer using the novel oral fluoropyrimidine S-1 Oncol Rep 9 1355 1361
-
(2002)
Oncol Rep
, vol.9
, pp. 1355-1361
-
-
Hayashi, K.1
Imaizumi, T.2
Uchida, K.3
Kuramochi, H.4
Takasaki, K.5
-
12
-
-
6544263262
-
Pharmacokinetic study of S-1, a novel oral fluorouracil antitumor drug
-
K Hirata N Horikoshi K Aiba M Okazaki R Denno K Sasaki Y Nakano H Ishizuka Y Yamada S Uno T Taguchi T Shirasaka 1999 Pharmacokinetic study of S-1, a novel oral fluorouracil antitumor drug Clin Cancer Res 5 2000 2005
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2000-2005
-
-
Hirata, K.1
Horikoshi, N.2
Aiba, K.3
Okazaki, M.4
Denno, R.5
Sasaki, K.6
Nakano, Y.7
Ishizuka, H.8
Yamada, Y.9
Uno, S.10
Taguchi, T.11
Shirasaka, T.12
-
13
-
-
6944226476
-
Thymidylate synthase predictive power is overcome by irinotecan combination therapy with S-1 for gastric cancer
-
W Ichikawa T Takahashi K Suto T Yamashita Z Nihei Y Shirota M Shimizu Y Sasaki R Hirayama 2004 Thymidylate synthase predictive power is overcome by irinotecan combination therapy with S-1 for gastric cancer Br J Cancer 91 1245 1250
-
(2004)
Br J Cancer
, vol.91
, pp. 1245-1250
-
-
Ichikawa, W.1
Takahashi, T.2
Suto, K.3
Yamashita, T.4
Nihei, Z.5
Shirota, Y.6
Shimizu, M.7
Sasaki, Y.8
Hirayama, R.9
-
14
-
-
27744561694
-
Immunohistochemical demonstration of fluoropyrimidine-metabolizing enzymes in various types of cancer
-
S Kamoshida K Shiogama R Shimomura K Inada Y Sakurai M Ochiai H Matuoka K Maeda Y Tsutsumi 2005 Immunohistochemical demonstration of fluoropyrimidine- metabolizing enzymes in various types of cancer Oncol Rep 14 1223 1230
-
(2005)
Oncol Rep
, vol.14
, pp. 1223-1230
-
-
Kamoshida, S.1
Shiogama, K.2
Shimomura, R.3
Inada, K.4
Sakurai, Y.5
Ochiai, M.6
Matuoka, H.7
Maeda, K.8
Tsutsumi, Y.9
-
15
-
-
33745474963
-
5-fluorouracil-related gene expression levels in primary colorectal cancer and corresponding liver metastasis
-
H Kuramochi K Hayashi K Uchida S Miyakura D Shimizu D Vallbohmer S Park KD Danenberg K Takasaki PV Danenberg 2006 5-fluorouracil-related gene expression levels in primary colorectal cancer and corresponding liver metastasis Int J Cancer 119 522 526
-
(2006)
Int J Cancer
, vol.119
, pp. 522-526
-
-
Kuramochi, H.1
Hayashi, K.2
Uchida, K.3
Miyakura, S.4
Shimizu, D.5
Vallbohmer, D.6
Park, S.7
Danenberg, K.D.8
Takasaki, K.9
Danenberg, P.V.10
-
16
-
-
0034146097
-
Telomerase reverse transcriptase expression is increased early in the Barrett's metaplasia, dysplasia, adenocarcinoma sequence
-
RV Lord D Salonga KD Danenberg JH Peters TR DeMeester JM Park J Johansson KA Skinner P Chandrasoma SR DeMeester CG Bremner PI Tsai PV Danenberg 2000 Telomerase reverse transcriptase expression is increased early in the Barrett's metaplasia, dysplasia, adenocarcinoma sequence J Gastrointest Surg 4 135 142
-
(2000)
J Gastrointest Surg
, vol.4
, pp. 135-142
-
-
Lord, R.V.1
Salonga, D.2
Danenberg, K.D.3
Peters, J.H.4
Demeester, T.R.5
Park, J.M.6
Johansson, J.7
Skinner, K.A.8
Chandrasoma, P.9
Demeester, S.R.10
Bremner, C.G.11
Tsai, P.I.12
Danenberg, P.V.13
-
17
-
-
0012365921
-
Expression levels of thymidine phosphorylase and dihydropyrimidine dehydrogenase in various human tumor tissues
-
K Mori M Hasegawa M Nishida H Toma M Fukuda T Kubota N Nagasue H Yamana YSCK Hirakawa T Ikeda K Takasaki M Oka M Kameyama M Toi H Fujii M Kitamura M Murai H Sasaki S Ozono H Makuuchi Y Shimada Y Onishi S Aoyagi K Mizutani M Ogawa A Nakao H Kinoshita T Tono H Imamoto Y Nakashima T Manabe 2000 Expression levels of thymidine phosphorylase and dihydropyrimidine dehydrogenase in various human tumor tissues Int J Oncol 17 33 38
-
(2000)
Int J Oncol
, vol.17
, pp. 33-38
-
-
Mori, K.1
Hasegawa, M.2
Nishida, M.3
Toma, H.4
Fukuda, M.5
Kubota, T.6
Nagasue, N.7
Yamana, H.8
Ysck, H.9
Ikeda, T.10
Takasaki, K.11
Oka, M.12
Kameyama, M.13
Toi, M.14
Fujii, H.15
Kitamura, M.16
Murai, M.17
Sasaki, H.18
Ozono, S.19
Makuuchi, H.20
Shimada, Y.21
Onishi, Y.22
Aoyagi, S.23
Mizutani, K.24
Ogawa, M.25
Nakao, A.26
Kinoshita, H.27
Tono, T.28
Imamoto, H.29
Nakashima, Y.30
Manabe, T.31
more..
-
18
-
-
0034676238
-
Therapeutic effect of 1 M tegafur-0.4 M 5-chloro-2, 4-dihydroxypridine-1 M potassium oxonate (S-1) on head and neck squamous carcinoma cells
-
G Nishimura S Yanoma H Mizuno K Satake T Taguchi Y Ikeda M Tsukuda 2000 Therapeutic effect of 1 M tegafur-0.4 M 5-chloro-2, 4-dihydroxypridine-1 M potassium oxonate (S-1) on head and neck squamous carcinoma cells Cancer Lett 159 1 7
-
(2000)
Cancer Lett
, vol.159
, pp. 1-7
-
-
Nishimura, G.1
Yanoma, S.2
Mizuno, H.3
Satake, K.4
Taguchi, T.5
Ikeda, Y.6
Tsukuda, M.7
-
19
-
-
0028888708
-
Long-term survival after resection for ductal adenocarcinoma of the pancreas. Is it really improving?
-
SS Nitecki MG Sarr TV Colby JA van Heerden 1995 Long-term survival after resection for ductal adenocarcinoma of the pancreas. Is it really improving? Ann Surg 221 59 66
-
(1995)
Ann Surg
, vol.221
, pp. 59-66
-
-
Nitecki, S.S.1
Sarr, M.G.2
Colby, T.V.3
Van Heerden, J.A.4
-
20
-
-
0034089123
-
Phase II study of S-1, a novel oral fluorophyrimidine derivative, in patients with metastatic colorectal carcinoma. S-1 Cooperative Colorectal Carcinoma Study Group
-
A Ohtsu H Baba Y Sakata Y Mitachi N Horikoshi K Sugimachi T Taguchi 2000 Phase II study of S-1, a novel oral fluorophyrimidine derivative, in patients with metastatic colorectal carcinoma. S-1 Cooperative Colorectal Carcinoma Study Group Br J Cancer 83 141 145
-
(2000)
Br J Cancer
, vol.83
, pp. 141-145
-
-
Ohtsu, A.1
Baba, H.2
Sakata, Y.3
Mitachi, Y.4
Horikoshi, N.5
Sugimachi, K.6
Taguchi, T.7
-
21
-
-
0024347268
-
Biochemical modulation of fluorouracil: Evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma
-
MA Poon MJ O'Connell CG Moertel HS Wieand SA Cullinan LK Everson JE Krook JA Mailliard JA Laurie LK Tschetter 1989 Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma J Clin Oncol 7 1407 1418
-
(1989)
J Clin Oncol
, vol.7
, pp. 1407-1418
-
-
Poon, M.A.1
O'Connell, M.J.2
Moertel, C.G.3
Wieand, H.S.4
Cullinan, S.A.5
Everson, L.K.6
Krook, J.E.7
Mailliard, J.A.8
Laurie, J.A.9
Tschetter, L.K.10
-
22
-
-
16544365052
-
A phase II study of S-1 in patients with metastatic breast cancer-a Japanese trial by the S-1 Cooperative Study Group, Breast Cancer Working Group
-
T Saek S Takashima M Sano N Horikoshi S Miura S Shimizu K Morimoto M Kimura H Aoyama J Ota S Noguchi T Taguchi 2004 A phase II study of S-1 in patients with metastatic breast cancer-a Japanese trial by the S-1 Cooperative Study Group, Breast Cancer Working Group Breast Cancer 11 194 202
-
(2004)
Breast Cancer
, vol.11
, pp. 194-202
-
-
Saek, T.1
Takashima, S.2
Sano, M.3
Horikoshi, N.4
Miura, S.5
Shimizu, S.6
Morimoto, K.7
Kimura, M.8
Aoyama, H.9
Ota, J.10
Noguchi, S.11
Taguchi, T.12
-
23
-
-
0032189218
-
Late phase II study of novel oral fluoropyrimidine anticancer drug S-1 (1 M tegafur-0.4 M gimestat-1 M otastat potassium) in advanced gastric cancer patients
-
Y Sakata A Ohtsu N Horikoshi K Sugimachi Y Mitachi T Taguchi 1998 Late phase II study of novel oral fluoropyrimidine anticancer drug S-1 (1 M tegafur-0.4 M gimestat-1 M otastat potassium) in advanced gastric cancer patients Eur J Cancer 34 1715 1720
-
(1998)
Eur J Cancer
, vol.34
, pp. 1715-1720
-
-
Sakata, Y.1
Ohtsu, A.2
Horikoshi, N.3
Sugimachi, K.4
Mitachi, Y.5
Taguchi, T.6
-
24
-
-
0029835349
-
Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators
-
T Shirasaka Y Shimamato H Ohshimo M Yamaguchi T Kato K Yonekura M Fukushima 1996 Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators Anticancer Drugs 7 548 557
-
(1996)
Anticancer Drugs
, vol.7
, pp. 548-557
-
-
Shirasaka, T.1
Shimamato, Y.2
Ohshimo, H.3
Yamaguchi, M.4
Kato, T.5
Yonekura, K.6
Fukushima, M.7
-
25
-
-
0036275282
-
Enhancement of the antitumour activity of 5-fluorouracil (5-FU) by inhibiting dihydropyrimidine dehydrogenase activity (DPD) using 5-chloro-2,4-dihydroxypyridine (CDHP) in human tumour cells
-
T Takechi A Fujioka E Matsushima M Fukushima 2002 Enhancement of the antitumour activity of 5-fluorouracil (5-FU) by inhibiting dihydropyrimidine dehydrogenase activity (DPD) using 5-chloro-2,4-dihydroxypyridine (CDHP) in human tumour cells Eur J Cancer 38 1271 1277
-
(2002)
Eur J Cancer
, vol.38
, pp. 1271-1277
-
-
Takechi, T.1
Fujioka, A.2
Matsushima, E.3
Fukushima, M.4
-
26
-
-
0023250474
-
Inhibitory effects of pyrimidine, barbituric acid and pyridine derivatives on 5-fluorouracil degradation in rat liver extracts
-
K Tatsumi M Fukushima T Shirasaka S Fujii 1987 Inhibitory effects of pyrimidine, barbituric acid and pyridine derivatives on 5-fluorouracil degradation in rat liver extracts Jpn J Cancer Res 78 748 755
-
(1987)
Jpn J Cancer Res
, vol.78
, pp. 748-755
-
-
Tatsumi, K.1
Fukushima, M.2
Shirasaka, T.3
Fujii, S.4
-
27
-
-
0032745499
-
Relationship between intratumoral dihydropyrimidine dehydrogenase activity and gene expression in human colorectal cancer
-
H Uetake W Ichikawa T Takechi M Fukushima Z Nihei K Sugihara 1999 Relationship between intratumoral dihydropyrimidine dehydrogenase activity and gene expression in human colorectal cancer Clin Cancer Res 5 2836 2839
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2836-2839
-
-
Uetake, H.1
Ichikawa, W.2
Takechi, T.3
Fukushima, M.4
Nihei, Z.5
Sugihara, K.6
|