Hypertonic saline up-regulates A3 adenosine receptor expression of activated neutrophils and increases acute lung injury after sepsis

Critical Care Medicine

Volumn 36, Issue 9, 2008, Pages 2569-2575

  Inoue, Yoshiaki ^a   Chen, Yu ^a   Pauzenberger, Reinhard ^a   Hirsh, Mark I ^a   Jnger, Wolfgang G ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

A3 adenosine receptor; Acute lung injury; Hypertonic saline resuscitation; Polymorphonuclear neutrophils; Sepsis

Indexed keywords

ADENOSINE A3 RECEPTOR; FORMYLMETHIONYLLEUCYLPHENYLALANINE; SODIUM CHLORIDE; PANCREATIC ELASTASE; PEROXIDASE;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CECUM; CLINICAL RESEARCH; CONTROLLED STUDY; DEGRANULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; KNOCKOUT MOUSE; LABORATORY; LABORATORY TEST; LIGATION; MALE; MORTALITY; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUNCTURE; RESUSCITATION; SEPSIS; UNIVERSITY; UPREGULATION; WILD TYPE; ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL; BIOSYNTHESIS; LUNG; METABOLISM; MOUSE MUTANT; PATHOLOGY; PERITONEAL CAVITY; PHYSIOLOGY; RANDOMIZATION; TIME;

ANIMALS; CELL DEGRANULATION; HUMANS; LUNG; MICE; MICE, KNOCKOUT; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; PANCREATIC ELASTASE; PERITONEAL CAVITY; PEROXIDASE; RANDOM ALLOCATION; RECEPTOR, ADENOSINE A3; RESPIRATORY DISTRESS SYNDROME, ADULT; SALINE SOLUTION, HYPERTONIC; SEPSIS; TIME FACTORS;

EID: 53049108397     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3181841a91     Document Type: Article

References (34)

1. Botha AJ, Moore FA, Moore EE, et al: Early neutrophil sequestration after injury: A pathogenic mechanism for multiple organ failure. J Trauma 1995; 39:411-417
2. Ware LB, Matthay MA: The acute respiratory distress syndrome. N Engl J Med 2000; 342: 1334-1349
3. American College of Chest Physicians/ Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992; 20:864-874
4. Velasco IT, Pontieri V, Rocha-e-Silva M, et al: Hyperosmotic NaCl and severe hemorrhagic shock. Am J Physiol 1980; 239:H664-H673
5. Velasco IT, Rocha e Silva M, Oliveira MA, et al: Hypertonic and hyperoncotic resuscitation from severe hemorrhagic shock in dogs: A comparative study. Crit Care Med 1989; 17:262-264
6. Younes RN, Aun F, Tomida RM, et al: The role of lung innervation in the hemodynamic response to hypertonic sodium chloride solutions in hemorrhagic shock. Surgery 1985; 98:900-906
7. Junger WG, Liu FC, Loomis WH, et al: Hy-pertonic saline enhances cellular immune function. Circ Shock 1994; 42:190-196
8. Junger WG, Hoyt DB, Davis RE, et al: Hyper-tonicity regulates the function of human neutrophils by modulating chemoattractant receptor signaling and activating mitogen-activated protein kinase p38. J Clin Invest 1998; 101:2768-2779
9. Angle N, Hoyt DB, Coimbra R, et al: Hyper-tonic saline resuscitation diminishes lung injury by suppressing neutrophil activation after hemorrhagic shock. Shock 1998; 9:164-170
10. Junger WG, Coimbra R, Liu FC, et al: Hyper-tonic saline resuscitation: A tool to modulate immune function in trauma patients? Shock 1997; 8:235-241
11. Rizoli SB, Kapus A, Fan J, et al: Immunomodulatory effects of hypertonic resuscitation on the development of lung inflammation following hemorrhagic shock. J Immunol 1998; 161: 6288-6296
12. Rostein OD: Novel strategies for immuno-modulation after trauma: Revisiting hypertonic saline as a resuscitation strategy for hemor-rhagic shock. J Trauma 2000; 49:580-583
13. Ciesla DJ, Moore EE, Zallen G, et al: Hyper-tonic saline attenuation of polymorphonu-clear neutrophil cytotoxicity: Timing is everything. J Trauma 2000; 48:388-395
14. Angle N, Hoyt DB, Cabello-Passini R, et al: Hypertonic resuscitation reduces neutrophil margination by suppressing neutrophil L se-lectin expression. J Trauma 1998; 45:7-13
15. Murao Y, Hoyt DB, Loomis W, et al: Does the timing of hypertonic saline resuscitation affect its potential to prevent lung damage? Shock 2000; 14:18-23
16. Murao Y, Loomis W, Wolf P, et al: Effect of dose of hypertonic saline on its potential to prevent lung tissue damage in a mouse model of hemorrhagic shock. Shock 2003; 20:29-34
17. Chen Y, Hashiguchi N, Yip L, et al: Hyper-tonic saline enhances neutrophil elastase release through activation of P2 and A3 receptors. Am J Physiol Cell Physiol 2006; 290: C1051-C1059
18. Hashiguchi N, Lum L, Romeril E, et al: Hy-pertonic saline resuscitation: Efficacy may require early treatment in severely injured patients. J Trauma 2007; 62:299-306
19. Orlic T, Loomis WH, Namiki S, et al: Hyperto-nicity increases cAMP in PMN and blocks oxi-dative burst by PKA-dependent and-indepen-dent mechanisms. Am J Physiol Cell Physiol 2002; 282:C1261-C1269
20. Chen Y, Corriden R, Inoue Y, et al: ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science 2006; 314: 1792-1795
21. Chen Y, Shukla A, Namiki S, et al: A putative osmoreceptor system that controls neutro-phil function through the release of ATP, its conversion to adenosine, and activation of A2 adenosine and P2 receptors. J Leukocyto Biol 2004; 76:245-253
22. Nick JA, Avdi NJ, Young SK, et al: Common and distinct intracellular signaling pathways in human neutrophils utilized by platelet activating factor and FMLP. J Clin Invest 1997; 99:975-986
23. Sato N, Kashima K, Shimazu H, et al: Hy-pertonic glucose inhibits the production of oxygen-derived free radicals by rat neutro-phils. Life Sci 1993; 52:1481-1486
24. Baker CC, Chaudry IH, Gaines HO, et al: Evaluation of factors affecting mortality rate after sepsis in a murine cecal ligation and puncture model. Surgery 1983; 94:331-335
25. Chiara O, Pelosi P, Brazzi L, et al: Resuscitation from hemorrhagic shock: Experimental model comparing normal saline, dextran, and hypertonic saline solutions. Crit Care Med 2003; 31:1915-1922
26. Vachharajani V, Vital S, Russell J, et al: Hypertonic saline and the cerebral microcirculation in obese septic mice. Microcirculation 2007; 14:223-231
27. Yip L, Cheung CW, Corriden R, et al: Hyper-tonic stress regulates T-cell function by the opposing actions of extracellular adenosine triphosphate and adenosine. Shock 2007; 27: 242-250
28. Fujiyoshi N, Deitch EA, Feketeova E, et al: Amiloride combined with small-volume resuscitation with hypertonic saline is superior in ameliorating trauma-hemorrhagic shock-induced lung injury in rats to the administration of either agent alone. Crit Care Med 2005; 33:2592-2598
29. Homma H, Deitch EA, Feketeova E, et al: Small volume resuscitation with hypertonic saline is more effective in ameliorating trauma-hemorrhagic shock-induced lung injury, neutrophil activation and red blood cell dysfunction than pancreatitic protease inhibition. J Trauma 2005; 59:266-272
30. Wilder DM, Reid TJ, Bakaltcheva IB: Hy-pertonic resuscitation and blood coagulation: In vitro comparison of several hyper-tonic solutions for their action on platelets and plasma coagulation. Thromb Res 2002; 107:255-261
31. Giusti-Paiva A, Martinez MR, Bispo-da-Silva LB, et al: Vasopressin mediates the pressor effect of hypertonic saline solution in endo-toxic shock. Shock 2007; 27:416-421
32. Poli-de-Figueiredo LF, Cruz RJ Jr, San-nomiya P, et al: Mechanisms of action of hypertonic saline resuscitation in severe sepsis and septic shock. Endocr Metab Immune Disord Drug Targets 2006; 6:201-206
33. Oi Y, Aneman A, Svensson M, et al: Hyper-tonic saline-dextran improves intestinal perfusion and survival in porcine endo-toxin shock. Crit Care Med 2000; 28: 2843-2850
34. Oliveira RP, Velasco I, Soriano FG, et al: Clinical review: Hypertonic saline resuscitation in sepsis. Crit Care 2002; 6:418-423