LC-UV-PDA and LC-MS studies to characterize degradation products of glimepiride

Journal of Pharmaceutical and Biomedical Analysis

Volumn 48, Issue 3, 2008, Pages 788-795

  Bansal, Gulshan ^a   Singh, Manjeet ^a   Jindal, K C ^b   Singh, Saranjit ^c  

^a PUNJABI UNIVERSITY   (India)

^b Panacea Biotec Ltd   (India)

^c NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Degradation products; Forced degradation; Glimepiride; LC MS; Mass fragmentation pattern

Indexed keywords

[[4 [2 (N CARBAMOYL)AMINOETHYL]PHENYL]SULFONYL] 3 (4 METHYLCYCLOHEXYL)UREA; GLIMEPIRIDE; GLIMEPIRIDE DERIVATIVE; GLIMEPIRIDE SULFONAMIDE; GLIMEPIRIDE URETHANE; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ARTICLE; DRUG DECOMPOSITION; DRUG DEGRADATION; HYDROLYSIS; INSTRUMENT STERILIZATION; LIGHT EMITTING DIODE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; OXIDATION; PHOTODIODE ARRAY; PHOTOLYSIS; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY;

CHROMATOGRAPHY, LIQUID; DRUG CONTAMINATION; HOT TEMPERATURE; HYDROLYSIS; HYPOGLYCEMIC AGENTS; MASS SPECTROMETRY; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PHARMACOPOEIAS AS TOPIC; PHOTOLYSIS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET; SULFONYLUREA COMPOUNDS;

EID: 53049107568     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2008.08.003     Document Type: Article

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