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Volumn 75, Issue 11, 2008, Pages 1637-1652

Integration of CREB and bHLH transcriptional signaling pathways through direct heterodimerization of the proteins: Role in muscle and testis development

Author keywords

ATF4; bHLH; cAMP signal transduction; CREB; Knockout; Muscle; Paraxis; Scleraxis; Sertoli cell; Spermatogenesis; Testis; Transcriptional control

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; HETERODIMER; LEUCINE ZIPPER PROTEIN; MYOD PROTEIN;

EID: 53049099346     PISSN: 1040452X     EISSN: 10982795     Source Type: Journal    
DOI: 10.1002/mrd.20902     Document Type: Article
Times cited : (18)

References (51)
  • 2
    • 1442307970 scopus 로고    scopus 로고
    • Anoxic induction of ATF-4 through HIF-1-independent pathways of protein stabilization in human cancer cells
    • Ameri K, Lewis CE, Raida M, Sowter H, Hai T, Harris AL. 2004. Anoxic induction of ATF-4 through HIF-1-independent pathways of protein stabilization in human cancer cells. Blood 103:1876-1882.
    • (2004) Blood , vol.103 , pp. 1876-1882
    • Ameri, K.1    Lewis, C.E.2    Raida, M.3    Sowter, H.4    Hai, T.5    Harris, A.L.6
  • 4
    • 0024453704 scopus 로고
    • A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts
    • Braun T, Buschhausen-Denker G, Bober E, Tannich E, Arnold HH. 1989. A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts. EMBO J 8:701-709.
    • (1989) EMBO J , vol.8 , pp. 701-709
    • Braun, T.1    Buschhausen-Denker, G.2    Bober, E.3    Tannich, E.4    Arnold, H.H.5
  • 6
    • 0029807350 scopus 로고    scopus 로고
    • Requirement of the paraxis gene for somite formation and musculoskeletal patterning
    • Burgess R, Rawls A, Brown D, Bradley A, Olson EN. 1996. Requirement of the paraxis gene for somite formation and musculoskeletal patterning. Nature 384:570-573.
    • (1996) Nature , vol.384 , pp. 570-573
    • Burgess, R.1    Rawls, A.2    Brown, D.3    Bradley, A.4    Olson, E.N.5
  • 7
    • 0032963421 scopus 로고    scopus 로고
    • E-box and cyclic adenosine monophosphate response elements are both required for follicle-stimulating hormone-induced transferrin promoter activation in Sertoli cells
    • Chaudhary J, Skinner MK. 1999. E-box and cyclic adenosine monophosphate response elements are both required for follicle-stimulating hormone-induced transferrin promoter activation in Sertoli cells. Endocrinology 140:1262-1271.
    • (1999) Endocrinology , vol.140 , pp. 1262-1271
    • Chaudhary, J.1    Skinner, M.K.2
  • 8
    • 0034917515 scopus 로고    scopus 로고
    • Role of the transcriptional coactivator CBP/p300 in linking basic helix-loop-helix and CREB responses for follicle-stimulating hormone-mediated activation of the transferrin promoter in Sertoli cells
    • Chaudhary J, Skinner MK. 2001. Role of the transcriptional coactivator CBP/p300 in linking basic helix-loop-helix and CREB responses for follicle-stimulating hormone-mediated activation of the transferrin promoter in Sertoli cells. Biol Reprod 65:568-574.
    • (2001) Biol Reprod , vol.65 , pp. 568-574
    • Chaudhary, J.1    Skinner, M.K.2
  • 9
    • 17444378923 scopus 로고    scopus 로고
    • The helix-loop-helix inhibitor of differentiation (ID) proteins induce postmitotic terminally differentiated Sertoli cells to re-enter the cell cycle and proliferate
    • Chaudhary J, Sadler-Riggleman I, Ague JM, Skinner MK. 2005. The helix-loop-helix inhibitor of differentiation (ID) proteins induce postmitotic terminally differentiated Sertoli cells to re-enter the cell cycle and proliferate. Biol Reprod 72:1205-1217.
    • (2005) Biol Reprod , vol.72 , pp. 1205-1217
    • Chaudhary, J.1    Sadler-Riggleman, I.2    Ague, J.M.3    Skinner, M.K.4
  • 10
    • 0035988260 scopus 로고    scopus 로고
    • Testis developmental phenotypes in neurotropin receptor trkA and trkC null mutations: Role in formation of seminiferous cords and germ cell survival
    • Cupp AS, Tessarollo L, Skinner MK. 2002. Testis developmental phenotypes in neurotropin receptor trkA and trkC null mutations: Role in formation of seminiferous cords and germ cell survival. Biol Reprod 66:1838-1845.
    • (2002) Biol Reprod , vol.66 , pp. 1838-1845
    • Cupp, A.S.1    Tessarollo, L.2    Skinner, M.K.3
  • 11
    • 0037025326 scopus 로고    scopus 로고
    • The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism
    • Dai YS, Cserjesi P, Markham BE, Molkentin JD. 2002. The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism. J Biol Chem 277:24390-24398.
    • (2002) J Biol Chem , vol.277 , pp. 24390-24398
    • Dai, Y.S.1    Cserjesi, P.2    Markham, B.E.3    Molkentin, J.D.4
  • 12
    • 0023663888 scopus 로고
    • Expression of a single transfected cDNA converts fibroblasts to myoblasts
    • Davis RL, Weintraub H, Lassar AB. 1987. Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell 51: 987-1000.
    • (1987) Cell , vol.51 , pp. 987-1000
    • Davis, R.L.1    Weintraub, H.2    Lassar, A.B.3
  • 13
    • 0024673511 scopus 로고
    • A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program
    • Edmondson DG, Olson EN. 1989. A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program. Genes Dev 3:628-640.
    • (1989) Genes Dev , vol.3 , pp. 628-640
    • Edmondson, D.G.1    Olson, E.N.2
  • 14
    • 0031882143 scopus 로고    scopus 로고
    • Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1
    • Firulli AB, McFadden DG, Lin Q, Srivastava D, Olson EN. 1998. Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1. Nat Genet 18:266-270.
    • (1998) Nat Genet , vol.18 , pp. 266-270
    • Firulli, A.B.1    McFadden, D.G.2    Lin, Q.3    Srivastava, D.4    Olson, E.N.5
  • 15
    • 0034721779 scopus 로고    scopus 로고
    • The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function
    • Firulli BA, Hadzic DB, McDaid JR, Firulli AB. 2000. The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function. J Biol Chem 275:33567-33573.
    • (2000) J Biol Chem , vol.275 , pp. 33567-33573
    • Firulli, B.A.1    Hadzic, D.B.2    McDaid, J.R.3    Firulli, A.B.4
  • 17
    • 0742323941 scopus 로고    scopus 로고
    • Activating transcription factor 4 is required for the differentiation of the lamina propria layer of the vas deferens
    • Fischer C, Johnson J, Stillwell B, Conner J, Cerovac Z, Wilson-Rawls J, Rawls A. 2004. Activating transcription factor 4 is required for the differentiation of the lamina propria layer of the vas deferens. Biol Reprod 70:371-378.
    • (2004) Biol Reprod , vol.70 , pp. 371-378
    • Fischer, C.1    Johnson, J.2    Stillwell, B.3    Conner, J.4    Cerovac, Z.5    Wilson-Rawls, J.6    Rawls, A.7
  • 18
    • 0025878233 scopus 로고
    • Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity
    • Hai T, Curran T. 1991. Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity. Proc Natl Acad Sci USA 88:3720-3724.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3720-3724
    • Hai, T.1    Curran, T.2
  • 19
    • 0035948624 scopus 로고    scopus 로고
    • The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: Activating transcription factor proteins and homeostasis
    • Hai T, Hartman MG. 2001. The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: Activating transcription factor proteins and homeostasis. Gene 273:1-11.
    • (2001) Gene , vol.273 , pp. 1-11
    • Hai, T.1    Hartman, M.G.2
  • 20
    • 0035877643 scopus 로고    scopus 로고
    • Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation
    • He CH, Gong P, Hu B, Stewart D, Choi ME, Choi AM, Alam J. 2001. Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation. J Biol Chem 276:20858-20865.
    • (2001) J Biol Chem , vol.276 , pp. 20858-20865
    • He, C.H.1    Gong, P.2    Hu, B.3    Stewart, D.4    Choi, M.E.5    Choi, A.M.6    Alam, J.7
  • 22
    • 20744437414 scopus 로고    scopus 로고
    • Inhibition of MuSK expression by CREB interacting with a CRE-like element and MyoD
    • Kim CH, Xiong WC, Mei L. 2005. Inhibition of MuSK expression by CREB interacting with a CRE-like element and MyoD. Mol Cell Biol 25:5329-5338.
    • (2005) Mol Cell Biol , vol.25 , pp. 5329-5338
    • Kim, C.H.1    Xiong, W.C.2    Mei, L.3
  • 23
    • 0030925073 scopus 로고    scopus 로고
    • Assembly of a bZIP-bHLH transcription activation complex: Formation of the yeast Cbf1-Met4-Met28 complex is regulated through Met28 stimulation of Cbf1 DNA binding
    • Kuras L, Barbey R, Thomas D. 1997. Assembly of a bZIP-bHLH transcription activation complex: Formation of the yeast Cbf1-Met4-Met28 complex is regulated through Met28 stimulation of Cbf1 DNA binding. EMBO J 16:2441-2451.
    • (1997) EMBO J , vol.16 , pp. 2441-2451
    • Kuras, L.1    Barbey, R.2    Thomas, D.3
  • 24
    • 0031566263 scopus 로고    scopus 로고
    • USF2/FIP associates with the b-Zip transcription factor, c-Maf, via its bHLH domain and inhibits c-Maf DNA binding activity
    • Kurschner C, Morgan JI. 1997. USF2/FIP associates with the b-Zip transcription factor, c-Maf, via its bHLH domain and inhibits c-Maf DNA binding activity. Biochem Biophys Res Commun 231:333-339.
    • (1997) Biochem Biophys Res Commun , vol.231 , pp. 333-339
    • Kurschner, C.1    Morgan, J.I.2
  • 25
    • 0026756149 scopus 로고
    • Cyclic AMP-dependent protein kinase inhibits the activity of myogenic helix-loop-helix proteins
    • Li L, Heller-Harrison R, Czech M, Olson EN. 1992. Cyclic AMP-dependent protein kinase inhibits the activity of myogenic helix-loop-helix proteins. Mol Cell Biol 12:4478-4485.
    • (1992) Mol Cell Biol , vol.12 , pp. 4478-4485
    • Li, L.1    Heller-Harrison, R.2    Czech, M.3    Olson, E.N.4
  • 26
    • 0028829831 scopus 로고
    • Dermo-1: A novel twist-related bHLH protein expressed in the developing dermis
    • Li L, Cserjesi P, Olson EN. 1995. Dermo-1: A novel twist-related bHLH protein expressed in the developing dermis. Dev Biol 172:280-292.
    • (1995) Dev Biol , vol.172 , pp. 280-292
    • Li, L.1    Cserjesi, P.2    Olson, E.N.3
  • 28
    • 0028215362 scopus 로고
    • Crystal structure of MyoD bHLH domain-DNA complex: Perspectives on DNA recognition and implications for transcriptional activation
    • Ma PC, Rould MA, Weintraub H, Pabo CO. 1994. Crystal structure of MyoD bHLH domain-DNA complex: Perspectives on DNA recognition and implications for transcriptional activation. Cell 77:451-459.
    • (1994) Cell , vol.77 , pp. 451-459
    • Ma, P.C.1    Rould, M.A.2    Weintraub, H.3    Pabo, C.O.4
  • 29
    • 0003073157 scopus 로고    scopus 로고
    • Identification of neurogenin, a vertebrate neuronal determination gene
    • Ma Q, Kintner C, Anderson DJ. 1996. Identification of neurogenin, a vertebrate neuronal determination gene. Cell 87:43-52.
    • (1996) Cell , vol.87 , pp. 43-52
    • Ma, Q.1    Kintner, C.2    Anderson, D.J.3
  • 30
    • 0035430282 scopus 로고    scopus 로고
    • Transcriptional regulation by the phosphorylation-dependent factor CREB
    • Mayr B, Montminy M. 2001. Transcriptional regulation by the phosphorylation-dependent factor CREB. Nat Rev Mol Cell Biol 2:599-609.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 599-609
    • Mayr, B.1    Montminy, M.2
  • 31
    • 0029590104 scopus 로고
    • Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins
    • Molkentin JD, Black BL, Martin JF, Olson EN. 1995. Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins. Cell 83:1125-1136.
    • (1995) Cell , vol.83 , pp. 1125-1136
    • Molkentin, J.D.1    Black, B.L.2    Martin, J.F.3    Olson, E.N.4
  • 32
    • 0030972807 scopus 로고    scopus 로고
    • Transcriptional regulation by cyclic AMP
    • Montminy M. 1997. Transcriptional regulation by cyclic AMP. Annu Rev Biochem 66:807-822.
    • (1997) Annu Rev Biochem , vol.66 , pp. 807-822
    • Montminy, M.1
  • 33
    • 23744516948 scopus 로고    scopus 로고
    • Role of the basic helix-loop-helix transcription factor, scleraxis, in the regulation of Sertoli cell function and differentiation
    • Muir T, Sadler-Riggleman I, Skinner MK. 2005. Role of the basic helix-loop-helix transcription factor, scleraxis, in the regulation of Sertoli cell function and differentiation. Mol Endocrinol 19:2164-2174.
    • (2005) Mol Endocrinol , vol.19 , pp. 2164-2174
    • Muir, T.1    Sadler-Riggleman, I.2    Skinner, M.K.3
  • 34
    • 33644861385 scopus 로고    scopus 로고
    • Role of the basic helix-loop-helix protein ITF2 in the hormonal regulation of Sertoli cell differentiation
    • Muir T, Sadler-Riggleman I, Stevens JD, Skinner MK. 2006. Role of the basic helix-loop-helix protein ITF2 in the hormonal regulation of Sertoli cell differentiation. Mol Reprod Dev 73:491-500.
    • (2006) Mol Reprod Dev , vol.73 , pp. 491-500
    • Muir, T.1    Sadler-Riggleman, I.2    Stevens, J.D.3    Skinner, M.K.4
  • 35
    • 34547767687 scopus 로고    scopus 로고
    • Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons
    • Murchison ND, Price BA, Conner DA, Keene DR, Olson EN, Tabin CJ, Schweitzer R. 2007. Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons. Development 134:2697-2708.
    • (2007) Development , vol.134 , pp. 2697-2708
    • Murchison, N.D.1    Price, B.A.2    Conner, D.A.3    Keene, D.R.4    Olson, E.N.5    Tabin, C.J.6    Schweitzer, R.7
  • 36
    • 0029743536 scopus 로고    scopus 로고
    • A new subclass of helix-loop-helix transcription factors expressed in paraxial mesoderm and chondrogenic cell lineages
    • Olson EN, Brown D, Burgess R, Cserjesi P. 1996. A new subclass of helix-loop-helix transcription factors expressed in paraxial mesoderm and chondrogenic cell lineages. Ann NY Acad Sci 785: 108-118.
    • (1996) Ann NY Acad Sci , vol.785 , pp. 108-118
    • Olson, E.N.1    Brown, D.2    Burgess, R.3    Cserjesi, P.4
  • 37
    • 18544396997 scopus 로고    scopus 로고
    • Mouse NIPK interacts with ATF4 and affects its transcriptional activity
    • Ord D, Ord T. 2003. Mouse NIPK interacts with ATF4 and affects its transcriptional activity. Exp Cell Res 286:308-320.
    • (2003) Exp Cell Res , vol.286 , pp. 308-320
    • Ord, D.1    Ord, T.2
  • 38
    • 0035808380 scopus 로고    scopus 로고
    • Crystal structure of the CCAAT box/enhancer-binding protein beta activating transcription factor-4 basic leucine zipper heterodimer in the absence of DNA
    • Podust LM, Krezel AM, Kim Y. 2001. Crystal structure of the CCAAT box/enhancer-binding protein beta activating transcription factor-4 basic leucine zipper heterodimer in the absence of DNA. J Biol Chem 276:505-513.
    • (2001) J Biol Chem , vol.276 , pp. 505-513
    • Podust, L.M.1    Krezel, A.M.2    Kim, Y.3
  • 39
    • 34250689012 scopus 로고    scopus 로고
    • Generation of transgenic tendon reporters, ScxGFP and ScxAP, using regulatory elements of the scleraxis gene
    • Pryce BA, Brent AE, Murchison ND, Tabin CJ, Schweitzer R. 2007. Generation of transgenic tendon reporters, ScxGFP and ScxAP, using regulatory elements of the scleraxis gene. Dev Dyn 236:1677-1682.
    • (2007) Dev Dyn , vol.236 , pp. 1677-1682
    • Pryce, B.A.1    Brent, A.E.2    Murchison, N.D.3    Tabin, C.J.4    Schweitzer, R.5
  • 40
    • 0028363145 scopus 로고
    • Cloning and characterization of a basic helix-loop-helix protein expressed in early mesoderm and the developing somites
    • Quertermous EE, Hidai H, Blanar MA, Quertermous T. 1994. Cloning and characterization of a basic helix-loop-helix protein expressed in early mesoderm and the developing somites. Proc Natl Acad Sci USA 91:7066-7070.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7066-7070
    • Quertermous, E.E.1    Hidai, H.2    Blanar, M.A.3    Quertermous, T.4
  • 41
    • 3142769033 scopus 로고    scopus 로고
    • The murine testicular transcriptome: Characterizing gene expression in the testis during the progression of spermatogenesis
    • Shima JE, McLean DJ, McCarrey JR, Griswold MD. 2004. The murine testicular transcriptome: Characterizing gene expression in the testis during the progression of spermatogenesis. Biol Reprod 71:319-330.
    • (2004) Biol Reprod , vol.71 , pp. 319-330
    • Shima, J.E.1    McLean, D.J.2    McCarrey, J.R.3    Griswold, M.D.4
  • 42
    • 12344329357 scopus 로고    scopus 로고
    • Profiling gene expression during the differentiation and development of the murine embryonic gonad
    • Small CL, Shima JE, Uzumcu M, Skinner MK, Griswold MD. 2005. Profiling gene expression during the differentiation and development of the murine embryonic gonad. Biol Reprod 72:492-501.
    • (2005) Biol Reprod , vol.72 , pp. 492-501
    • Small, C.L.1    Shima, J.E.2    Uzumcu, M.3    Skinner, M.K.4    Griswold, M.D.5
  • 43
    • 0029549692 scopus 로고
    • A subclass of bHLH proteins required for cardiac morphogenesis
    • Srivastava D, Cserjesi P, Olson EN. 1995. A subclass of bHLH proteins required for cardiac morphogenesis. Science 270:1995-1999.
    • (1995) Science , vol.270 , pp. 1995-1999
    • Srivastava, D.1    Cserjesi, P.2    Olson, E.N.3
  • 45
    • 0033385169 scopus 로고    scopus 로고
    • Differential regulation of epaxial and hypaxial muscle development by paraxis
    • Wilson-Rawls J, Hurt CR, Parsons SM, Rawls A. 1999a. Differential regulation of epaxial and hypaxial muscle development by paraxis. Development 126:5217-5229.
    • (1999) Development , vol.126 , pp. 5217-5229
    • Wilson-Rawls, J.1    Hurt, C.R.2    Parsons, S.M.3    Rawls, A.4
  • 46
    • 0032934985 scopus 로고    scopus 로고
    • Activated notch inhibits myogenic activity of the MADS-Box transcription factor myocyte enhancer factor 2C
    • Wilson-Rawls J, Molkentin JD, Black BL, Olson EN. 1999b. Activated notch inhibits myogenic activity of the MADS-Box transcription factor myocyte enhancer factor 2C. Mol Cell Biol 19:2853-2862.
    • (1999) Mol Cell Biol , vol.19 , pp. 2853-2862
    • Wilson-Rawls, J.1    Molkentin, J.D.2    Black, B.L.3    Olson, E.N.4
  • 47
    • 4444259353 scopus 로고    scopus 로고
    • Paraxis is a basic helix-loop-helix protein that positively regulates transcription through binding to specific E-box elements
    • Wilson-Rawls J, Rhee JM, Rawls A. 2004. Paraxis is a basic helix-loop-helix protein that positively regulates transcription through binding to specific E-box elements. J Biol Chem 279:37685-37692.
    • (2004) J Biol Chem , vol.279 , pp. 37685-37692
    • Wilson-Rawls, J.1    Rhee, J.M.2    Rawls, A.3
  • 48
    • 0027214875 scopus 로고
    • cAMP-dependent protein kinase represses myogenic differentiation and the activity of the muscle-specific helix-loop-helix transcription factors Myf-5 and MyoD
    • Winter B, Braun T, Arnold HH. 1993. cAMP-dependent protein kinase represses myogenic differentiation and the activity of the muscle-specific helix-loop-helix transcription factors Myf-5 and MyoD. J Biol Chem 268:9869-9878.
    • (1993) J Biol Chem , vol.268 , pp. 9869-9878
    • Winter, B.1    Braun, T.2    Arnold, H.H.3
  • 49
    • 0035824487 scopus 로고    scopus 로고
    • Requirement of Math1 for secretory cell lineage commitment in the mouse intestine
    • Yang Q, Bermingham NA, Finegold MJ, Zoghbi HY. 2001. Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science 294:2155-2158.
    • (2001) Science , vol.294 , pp. 2155-2158
    • Yang, Q.1    Bermingham, N.A.2    Finegold, M.J.3    Zoghbi, H.Y.4
  • 51
    • 0035894449 scopus 로고    scopus 로고
    • Sgn1, a basic helix-loop-helix transcription factor delineates the salivary gland duct cell lineage in mice
    • Yoshida S, Ohbo K, Takakura A, Takebayashi H, Okada T, Abe K, Nabeshima Y. 2001. Sgn1, a basic helix-loop-helix transcription factor delineates the salivary gland duct cell lineage in mice. Dev Biol 240:517-530.
    • (2001) Dev Biol , vol.240 , pp. 517-530
    • Yoshida, S.1    Ohbo, K.2    Takakura, A.3    Takebayashi, H.4    Okada, T.5    Abe, K.6    Nabeshima, Y.7


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