Efficacy of the amphibian peptide distinctin in a neutropenic mouse model of staphylococcal sepsis

Critical Care Medicine

Volumn 36, Issue 9, 2008, Pages 2629-2633

  Cirioni, Oscar ^a   Ghiselli, Roberto ^a   Orlando, Fiorenza ^b   Silvestri, Carmela ^a   De Luca, Stefania ^c   Salzano, Anna Maria ^c   Mocchegiani, Federico ^a   Saba, Vittorio ^a   Scalise, Giorgio ^a   Scaloni, Andrea ^c   Giacometti, Andrea ^a  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^b INRCA   (Italy)

^c CNR   (Italy)

Author keywords

Animal model; Neutropenia; S. aureus; Sepsis; Synergy

Indexed keywords

AMPHIBIAN PROTEIN; CYCLOPHOSPHAMIDE; DISTINCTIN; IMIPENEM; LINEZOLID; SODIUM CHLORIDE; TEICOPLANIN; UNCLASSIFIED DRUG; VANCOMYCIN; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL COUNT; BACTERIAL GROWTH; BACTERIAL STRAIN; BAGG ALBINO MOUSE; COLONY FORMING UNIT; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFICACY; DRUG POTENTIATION; EXPERIMENTAL INFECTION; HEMOLYSIS; LETHALITY; LIVER; MALE; MESENTERY LYMPH NODE; MINIMUM INHIBITORY CONCENTRATION; MONOTHERAPY; MOUSE; NEUTROPENIA; NONHUMAN; PERITONEUM; PRIORITY JOURNAL; PROSPECTIVE STUDY; SPLEEN; STAPHYLOCOCCAL BACTEREMIA; ANIMAL; DOSE RESPONSE; DRUG COMBINATION; DRUG EFFECT; FROGS AND TOADS; ISOLATION AND PURIFICATION; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; RANDOMIZATION; SEPSIS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION;

AMPHIBIAN PROTEINS; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; ANURA; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; HEMOLYSIS; MALE; MICE; MICE, INBRED BALB C; MICROBIAL SENSITIVITY TESTS; NEUTROPENIA; RANDOM ALLOCATION; SEPSIS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 53049098526     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e318184430d     Document Type: Article

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