Tregs-based immunotherapy: An efficient way to fully inhibit acute and chronic rejection;Utilisation des lymphocytes T régulateurs en transplantation: Supprimer l'immunosuppression

Medecine/Sciences

Volumn 24, Issue 8-9, 2008, Pages 689-691

  Joffre, Olivier ^a,b   Santolaria, Thibault ^a   Van Meerwijk, Joost P M ^a,c,d  

^a INSERM   (France)

^b Immunobiology Lab   (United Kingdom)

^c UNIVERSITÉ PAUL SABATIER   (France)

^d INSTITUT UNIVERSITAIRE DE FRANCE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE GRAFT REJECTION; CHRONIC GRAFT REJECTION; HUMAN; IMMUNOTHERAPY; NOTE; REGULATORY T LYMPHOCYTE;

EID: 53049089503     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/20082489689     Document Type: Note

References (11)

1. Billingham RE, Brent L, Medawar PB. Actively acquired tolerance of foreign cells. Nature 1953 ; 172 : 603-6.
2. Kawai T, Cosimi AB, Spitzer TR, et al. HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med 2008 ; 358 : 353-61.
3. Coutinho A, Salaun J, Corbel C, et al. The role of thymic epithelium in the establishment of transplantation tolerance. Immunol Rev 1993 ; 133 : 225-40.
4. Sakaguchi S, Sakaguchi N, Asano M, et al. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995 ; 155 : 1151-64.
5. + regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 2004 ; 22 : 531-62.
6. + regulatory T cells. J Immunol 2002 ; 168 : 1644-8.
7. Joffre O, Gorsse N, Romagnoli P, et al. Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytes. Blood 2004 ; 103 : 4216-21.
8. Joffre O, Santolaria T, Calise D, et al. Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes. Nat Med 2008 ; 14 : 88-92.
9. + T reg cells. J Exp Med 2006 ; 203 : 1701-11.
10. Yamaguchi T, Hirota K, Nagahama K, et al. Control of immune responses by antigen-specific regulatory T cells expressing the folate receptor. Immunity 2007 ; 27 : 145-59.
11. Vocanson M, Hennino A, Chavagnac C, et al. Eczéma allergique de contact : comment ré-induire une tolérance ? Med Sci (Paris) 2006 ; 22 : 158-63.