Zic2-associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation

Human Molecular Genetics

Volumn 17, Issue 19, 2008, Pages 2986-2996

  Warr, Nicholas ^a   Powles Glover, Nicola ^a   Chappell, Anna ^b   Robson, Joan ^a   Norris, Dominic ^a   Arkell, Ruth M ^a,b  

^a MRC MAMMALIAN GENETICS UNIT   (United Kingdom)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ZIC 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DEVELOPMENT; CELL PROLIFERATION; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; DISEASE SEVERITY; EMBRYO; EMBRYONIC STRUCTURES; ENDODERM; FOREBRAIN; GASTRULATION; HOLOPROSENCEPHALY; MESODERM; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; NOTOCHORD; PHENOTYPIC VARIATION; PRECHORDAL PLATE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; CELL DEATH; CELL PROLIFERATION; GASTRULATION; HEDGEHOG PROTEINS; HOLOPROSENCEPHALY; HUMANS; MICE; MICE, INBRED C3H; MICE, KNOCKOUT; MUTATION; NOTOCHORD; ORGANIZERS, EMBRYONIC; PROSENCEPHALON; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

MAMMALIA;

EID: 52949154367     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddn197     Document Type: Article

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