Identification of STC1 as an β-amyloid activated gene in human brain microvascular endothelial cells using cDNA microarray

Biochemical and Biophysical Research Communications

Volumn 376, Issue 2, 2008, Pages 399-403

  Li, Keshen ^a   Dong, Daming ^b   Yao, Lifen ^b   Dai, Dawei ^b   Gu, Xuefeng ^c   Guo, Liang ^a  

^a HARBIN ENGINEERING UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^c Seoul National University   (South Korea)

Author keywords

Amyloid; cDNA microarray; Gene expression; Human brain microvascular endothelial cells; Stanniocalcin 1

Indexed keywords

AMYLOID BETA PROTEIN; BETA ACTIN; CALCIUM; CASPASE 8; EARLY GROWTH RESPONSE FACTOR 1; GENE PRODUCT; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; STANNNIOCALCIN 1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BRAIN BLOOD VESSEL; CONTROLLED STUDY; DNA MICROARRAY; DOSE TIME EFFECT RELATION; ENDOTHELIUM CELL; GENE; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NEUROTOXICITY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; STC1 GENE; UPREGULATION;

AMYLOID BETA-PROTEIN; APOPTOSIS; BRAIN; CAPILLARIES; CASPASE 8; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; GENE EXPRESSION PROFILING; GLYCOPROTEINS; HUMANS; MONOCYTES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEPTIDE FRAGMENTS; TRANS-ACTIVATION (GENETICS);

EID: 52949131881     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.08.158     Document Type: Article

References (18)

1. Humpel C., and Marksteiner J. Cerebrovascular damage as a cause for Alzheimer's disease. Curr. Neurovasc. Res. 2 (2005) 341-347
2. Iadecola C. Cerebrovascular effects of amyloid-β peptides: mechanisms and implications for Alzheimer's dementia. Cell. Mol. Neurobiol. 23 (2003) 681-689
3. Folin M., Baiguera S., Fioravanzo L., Conconi M.T., Grandi C., Nussdorfer G.G., and Parnigotto P.P. Caspase-8 activation and oxidative stress are involved in the cytotoxic effect of β-amyloid on rat brain microvascular endothelial cells. Int. J. Mol. Med. 17 (2006) 431-435
4. Giri R., Shen Y., Stins M., Du Yan S., Schmidt A.M., Stern D., Kim K.S., Zlokovic B., and Kalra V.K. β-Amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1. Am. J. Physiol. Cell Physiol. 279 (2000) C1772-C1781
5. Madsen K.L., Tavernini M.M., Yachimec C., Mendrick D.L., Alfonso P.J., Buergin M., Olsen H.S., Antonaccio M.J., Thomson A.B., and Fedorak R.N. Stanniocalcin: a novel protein regulating calcium and phosphate transport across mammalian intestine. Am. J. Physiol. Gastrointest. Liver Physiol. 274 (1998) G96-G102
6. Man S.M., Ma Y.R., Shang D.S., Zhao W.D., Li B., Guo D.W., Fang W.G., Zhu L., and Chen Y.H. Peripheral T cells overexpress MIP-1α to enhance its transendothelial migration in Alzheimer's disease. Neurobiol. Aging 28 (2007) 485-496
7. Kim J.R., Lee S.R., Chung H.J., Kim S., Baek S.H., Kim J.H., and Kim Y.S. Identification of amyloid β-peptide responsive genes by cDNA microarray technology: involvement of RTP801 in amyloid β-peptide toxicity. Exp. Mol. Med. 35 (2003) 403-411
8. Santiard-Baron D., Gosset P., Nicole A., Sinet P.M., Christen Y., and Ceballos-Picot I. Identification of β-amyloid-responsive genes by RNA differential display: early induction of a DNA damage-inducible gene, gadd45. Exp. Neurol. 158 (1999) 206-213
9. Manalo D.J., Rowan A., Lavoie T., Natarajan L., Kelly B.D., Ye S.Q., Garcia J.G., and Semenza G.L. Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1. Blood 105 (2005) 659-669
10. Soucek T., Cumming R., Dargusch R., Maher P., and Schubert D. The regulation of glucose metabolism by HIF-1 mediates a neuroprotective response to amyloid-β peptide. Neuron 39 (2003) 43-56
11. Chakraborty A., Brooks H., Zhang P., Smith W., McReynolds M.R., Hoying J.B., Bick R., Truong L., Poindexter B., Lan H., Elbjeirami W., and Sheikh-Hamad D. Stanniocalcin-1 regulates endothelial gene expression and modulates transendothelial migration of leukocytes. Am. J. Physiol. Renal Physiol. 292 (2007) F895-F904
12. Shukaliak J.A., and Dorovini-Zis K. Expression of the β-chemokines RANTES and MIP-1 β by human brain microvessel endothelial cells in primary culture. J. Neuropathol. Exp. Neurol. 59 (2000) 339-352
13. Giri R.K., Selvaraj S.K., and Kalra V.K. Amyloid peptide-induced cytokine and chemokine expression in THP-1 monocytes is blocked by small inhibitory RNA duplexes for early growth response-1 messenger RNA. J. Immunol. 170 (2003) 5281-5294
14. Reddy P.H. Mitochondrial dysfunction in aging and Alzheimer's disease: strategies to protect neurons. Antioxid. Redox Signal. 9 (2007) 1647-1658
15. Zhu X., Smith M.A., Perry G., and Aliev G. Mitochondrial failures in Alzheimer's disease. Am. J. Alzheimers Dis. Other Demen. 19 (2004) 345-352
16. Zhang K., Lindsberg P.J., Tatlisumak T., Kaste M., Olsen H.S., and Andersson L.C. Stanniocalcin: a molecular guard of neurons during cerebral ischemia. Proc. Natl. Acad. Sci. USA 97 (2000) 3637-3642
17. Raina A.K., Hochman A., Zhu X., Rottkamp C.A., Nunomura A., Siedlak S.L., Boux H., Castellani R.J., Perry G., and Smith M.A. Abortive apoptosis in Alzheimer disease. Acta. Neuropathol. (Berl.) 101 (2001) 305-310
18. Chen C., Jamaluddin M.S., Yan S., Sheikh-Hamad D., and Yao Q. Human stanniocalcin-1 blocks TNF-α-induced monolayer permeability in human coronary artery endothelial cells. Arterioscler. Thromb. Vasc. Biol. 28 (2008) 906-912