Synthesis of 3,5-disubstituted isoxazolines as protein tyrosine phosphatase 1B inhibitors

Medicinal Chemistry Research

Volumn 17, Issue 2-7, 2008, Pages 123-136

  Maurya, Rakesh ^a   Gupta, Prasoon ^a   Ahmad, Ghufran ^a   Yadav, Dinesh Kumar ^a   Chand, Kailash ^a   Singh, Amar Bahadur ^a   Tamrakar, Akhilesh K ^a   Srivastava, Arvind K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

1,3 Dipolar cycloaddition; Isoxazolines; Protein tyrosine phosphatases

Indexed keywords

2 [3 (2,4 DIMETHOXY PHENYL) 4,5 DIHYDRO ISOXAZOL 5 YL]PYRIDINE; 2 [3 (5 METHOXY 2,2 DIMETHYL 2H CHROMEN 6 YL) 4,5 DIHYDRO ISOXAZOL 5 YL]PYRIDINE; 3 (2,4 DIMETHOXY PHENYL) 5 (4 METHOXY PHENYL) 4,5 DIHYDRO ISOXAZOLE; 3 (2,4 DIMETHOXY PHENYL) 5 IMIDAZOL 1 YL 4,5 DIHYDRO ISOXAZOLE; 3 (2,4 DIMETHOXY PHENYL) 5 PHENYL 4,5 DIHYDRO ISOXAZOLE; 3 (2,4 DIMETHOXY PHENYL) 5 PHENYL 4,5 DIHYDRO ISOXAZOLE 4 CARBOXYLIC ACID METHYL ESTER; 3 (5 METHOXY 2,2 DIMETHYL 2H CHROMEN 6 YL) 5 (4 METHOXY PHENYL) 4,5 DIHYDRO ISOXAZOLE; 3 (5 METHOXY 2,2 DIMETHYL 2H CHROMEN 6 YL) 5 PHENYL 4,5 DIHYDRO ISOXAZOLE; 4 (5 PHENYL 4,5 DIHYDRO ISOXAZOL 3 YL)BENZENE 1,3 DIOL; 4 [3 (2,4 DIMETHOXY PHENYL) 4,5 DIHYDRO ISOXAZOL 5 YL]PYRIDINE; 5 METHOXY 2 (5 PHENYL 4,5 DIHYDRO ISOXAZOL 3 YL)PHENOL; ACETIC ACID 3 ACETOXY 4 (5 PHENYL 4,5 DIHYDRO ISOXAZOL 3 YL)PHENYL ESTER; ACETIC ACID 5 METHOXY 2 (5 PHENYL 4,5 DIHYDRO ISOXAZOL 3 YL)PHENYL ESTER; ISOXAZOLINE DERIVATIVE; METFORMIN; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; UNCLASSIFIED DRUG; VANADATE SODIUM;

ANIMAL EXPERIMENT; CONFERENCE PAPER; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; MALE; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

EID: 52949099917     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00044-007-9043-6     Document Type: Conference Paper

References (17)

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