A novel computer algorithm improves antibody epitope prediction using affinity-selected mimotopes: A case study using monoclonal antibodies against the West Nile virus E protein

Molecular Immunology

Volumn 46, Issue 1, 2008, Pages 125-134

  Denisova, Galina F ^a   Denisov, Dimitri A ^a   Yeung, Jeffrey ^a   Loeb, Mark B ^a   Diamond, Michael S ^b   Bramson, Jonathan L ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Epitope mapping; Flavivirus; Monoclonal antibody; Neutralization; Phage display

Indexed keywords

EPITOPE; MIMOTOPE; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; VIRUS PROTEIN; WEST NILE VIRUS E PROTEIN;

AMINO ACID SEQUENCE; ANTIBODY AFFINITY; ARTICLE; CRYSTAL STRUCTURE; EPITOPE MAPPING; FLAVIVIRUS; GENE MUTATION; IN VIVO STUDY; MOLECULAR MODEL; NONHUMAN; PHAGE DISPLAY; PREDICTION; PRIORITY JOURNAL; PROTEIN ISOLATION; WEST NILE FLAVIVIRUS;

ALGORITHMS; AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; COMPUTERS; EPITOPES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; STRUCTURAL HOMOLOGY, PROTEIN; VIRAL PROTEINS; WEST NILE VIRUS;

FLAVIVIRUS; WEST NILE VIRUS;

EID: 52949094267     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.07.020     Document Type: Article

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