-
1
-
-
33744814477
-
Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer
-
This paper and the next are among the first to validate commercial diagnostic arising from array-based expression genomic studies in large clinical studies paving the way for clinical use of these products in the primary care of cancer patients.
-
Paik S., Tang G., Shak S., Kim C., Baker J., Kim W., Cronin M., Baehner F.L., Watson D., Bryant J., et al. Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer. J Clin Oncol 24 August (23) (2006) 3726-3734. This paper and the next are among the first to validate commercial diagnostic arising from array-based expression genomic studies in large clinical studies paving the way for clinical use of these products in the primary care of cancer patients.
-
(2006)
J Clin Oncol
, vol.24
, Issue.August 23
, pp. 3726-3734
-
-
Paik, S.1
Tang, G.2
Shak, S.3
Kim, C.4
Baker, J.5
Kim, W.6
Cronin, M.7
Baehner, F.L.8
Watson, D.9
Bryant, J.10
-
2
-
-
33748693297
-
TRANSBIG Consortium. Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer
-
As noted above.
-
Buyse M., Loi S., van't Veer L., Viale G., Delorenzi M., Glas A.M., d'Assignies M.S., Bergh J., Lidereau R., Ellis P., et al. TRANSBIG Consortium. Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer. J Natl Cancer Inst 98 September (17) (2006) 1183-1192. As noted above.
-
(2006)
J Natl Cancer Inst
, vol.98
, Issue.September 17
, pp. 1183-1192
-
-
Buyse, M.1
Loi, S.2
van't Veer, L.3
Viale, G.4
Delorenzi, M.5
Glas, A.M.6
d'Assignies, M.S.7
Bergh, J.8
Lidereau, R.9
Ellis, P.10
-
3
-
-
33746875641
-
A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer
-
Potti A., Mukherjee S., Petersen R., Dressman H.K., Bild A., Koontz J., Kratzke R., Watson M.A., Kelley M., Ginsburg G.S., et al. A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer. N Engl J Med 355 August (6) (2006) 570-580
-
(2006)
N Engl J Med
, vol.355
, Issue.August 6
, pp. 570-580
-
-
Potti, A.1
Mukherjee, S.2
Petersen, R.3
Dressman, H.K.4
Bild, A.5
Koontz, J.6
Kratzke, R.7
Watson, M.A.8
Kelley, M.9
Ginsburg, G.S.10
-
4
-
-
33751261643
-
Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer
-
Ivshina A.V., George J., Senko O., Mow B., Putti T.C., Smeds J., Lindahl T., Pawitan Y., Hall P., et al. Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer. Cancer Res 66 (2006) 10292-10301
-
(2006)
Cancer Res
, vol.66
, pp. 10292-10301
-
-
Ivshina, A.V.1
George, J.2
Senko, O.3
Mow, B.4
Putti, T.C.5
Smeds, J.6
Lindahl, T.7
Pawitan, Y.8
Hall, P.9
-
5
-
-
33144462268
-
Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis
-
Sotiriou C., Wirapati P., Loi S., Harris A., Fox S., Smeds J., Nordgren H., Farmer P., Praz V., Haibe-Kains B., et al. Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis. J Natl Cancer Inst 98 (2006) 262-272
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 262-272
-
-
Sotiriou, C.1
Wirapati, P.2
Loi, S.3
Harris, A.4
Fox, S.5
Smeds, J.6
Nordgren, H.7
Farmer, P.8
Praz, V.9
Haibe-Kains, B.10
-
6
-
-
34250887474
-
Taking gene expression pofiling to the clinic: when will molecular signatures become relevant to patient care?
-
Sotiriou C., and Piccart M.J. Taking gene expression pofiling to the clinic: when will molecular signatures become relevant to patient care?. Nat Rev Cancer 7 July (2007) 545-552
-
(2007)
Nat Rev Cancer
, vol.7
, Issue.July
, pp. 545-552
-
-
Sotiriou, C.1
Piccart, M.J.2
-
7
-
-
33845884027
-
Integrative molecular concept modeling of prostate cancer progression
-
Using a clever application of an informatics mining approach, Arul Chinnaiyan's group identified transcriptional modules that might be drivers for prostate cancer progression.
-
Tomlins S.A., Mehra R., Rhodes D.R., Cao X., Wang L., Dhanasekaran S.M., Kalyana-Sundaram S., Wei J.T., Rubin M.A., Pienta K.J., et al. Integrative molecular concept modeling of prostate cancer progression. Nat Genet 39 January (1) (2007) 41-51. Using a clever application of an informatics mining approach, Arul Chinnaiyan's group identified transcriptional modules that might be drivers for prostate cancer progression.
-
(2007)
Nat Genet
, vol.39
, Issue.January 1
, pp. 41-51
-
-
Tomlins, S.A.1
Mehra, R.2
Rhodes, D.R.3
Cao, X.4
Wang, L.5
Dhanasekaran, S.M.6
Kalyana-Sundaram, S.7
Wei, J.T.8
Rubin, M.A.9
Pienta, K.J.10
-
8
-
-
41449118521
-
Module map of stem cell genes guides creation of epithelial cancer stem cells
-
Wong D.J., Liu H., Ridky T.W., Cassarino D., Segal E., and Chang H.Y. Module map of stem cell genes guides creation of epithelial cancer stem cells. Cell Stem Cell 2 April (4) (2008) 333-344
-
(2008)
Cell Stem Cell
, vol.2
, Issue.April 4
, pp. 333-344
-
-
Wong, D.J.1
Liu, H.2
Ridky, T.W.3
Cassarino, D.4
Segal, E.5
Chang, H.Y.6
-
9
-
-
41949098160
-
Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency
-
Hanna J., Markoulaki S., Schorderet P., Carey B.W., Beard C., Wernig M., Creyghton M.P., Steine E.J., Cassady J.P., Foreman R., et al. Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell 133 April (2) (2008) 250-264
-
(2008)
Cell
, vol.133
, Issue.April 2
, pp. 250-264
-
-
Hanna, J.1
Markoulaki, S.2
Schorderet, P.3
Carey, B.W.4
Beard, C.5
Wernig, M.6
Creyghton, M.P.7
Steine, E.J.8
Cassady, J.P.9
Foreman, R.10
-
10
-
-
41349090105
-
Generation of human induced pluripotent stem cells from dermal fibroblasts
-
Lowry W.E., Richter L., Yachechko R., Pyle A.D., Tchieu J., Sridharan R., Clark A.T., and Plath K. Generation of human induced pluripotent stem cells from dermal fibroblasts. Proc Natl Acad Sci U S A 105 February (8) (2008) 2883-2888
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.February 8
, pp. 2883-2888
-
-
Lowry, W.E.1
Richter, L.2
Yachechko, R.3
Pyle, A.D.4
Tchieu, J.5
Sridharan, R.6
Clark, A.T.7
Plath, K.8
-
11
-
-
39049127598
-
Revealing targeted therapy for human cancer by gene module maps
-
Wong D.J., Nuyten D.S., Regev A., Lin M., Adler A.S., Segal E., van de Vijver M.J., and Chang H.Y. Revealing targeted therapy for human cancer by gene module maps. Cancer Res 68 January (2) (2008) 369-378
-
(2008)
Cancer Res
, vol.68
, Issue.January 2
, pp. 369-378
-
-
Wong, D.J.1
Nuyten, D.S.2
Regev, A.3
Lin, M.4
Adler, A.S.5
Segal, E.6
van de Vijver, M.J.7
Chang, H.Y.8
-
12
-
-
41649092988
-
Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer
-
Acharya C.R., Hsu D.S., and Anders C.K. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer. JAMA 299 13 (2008) 1574-1587
-
(2008)
JAMA
, vol.299
, Issue.13
, pp. 1574-1587
-
-
Acharya, C.R.1
Hsu, D.S.2
Anders, C.K.3
-
13
-
-
40849124009
-
DNA methylation markers and early recurrence in stage I lung cancer
-
Brock M.V., Hooker C.M., Ota-Machida E., Han Y., Guo M., Ames S., Glöckner S., Piantadosi S., Gabrielson E., Pridham E., et al. DNA methylation markers and early recurrence in stage I lung cancer. N Engl J Med 358 March (11) (2008) 1118-1128
-
(2008)
N Engl J Med
, vol.358
, Issue.March 11
, pp. 1118-1128
-
-
Brock, M.V.1
Hooker, C.M.2
Ota-Machida, E.3
Han, Y.4
Guo, M.5
Ames, S.6
Glöckner, S.7
Piantadosi, S.8
Gabrielson, E.9
Pridham, E.10
-
14
-
-
33847065486
-
The epigenomics of cancer
-
Jones P.A., and Baylin S.B. The epigenomics of cancer. Cell 128 (2007) 683-692
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
15
-
-
33846649587
-
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
-
This is among the first descriptions of the linkage between H3K27 methylation and DNA methylation in cancer.
-
Schlesinger Y., Straussman R., Keshet I., Farkash S., Hecht M., Zimmerman J., Eden E., Yakhini Z., Ben-Shushan E., Reubinoff B.E., et al. Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nat Genet 39 February (2) (2007) 232-236. This is among the first descriptions of the linkage between H3K27 methylation and DNA methylation in cancer.
-
(2007)
Nat Genet
, vol.39
, Issue.February 2
, pp. 232-236
-
-
Schlesinger, Y.1
Straussman, R.2
Keshet, I.3
Farkash, S.4
Hecht, M.5
Zimmerman, J.6
Eden, E.7
Yakhini, Z.8
Ben-Shushan, E.9
Reubinoff, B.E.10
-
16
-
-
33750318686
-
Enhancer of Zeste 2 as a marker of preneoplastic progression in the breast
-
Ding L., and Kleer C.G. Enhancer of Zeste 2 as a marker of preneoplastic progression in the breast. Cancer Res 66 October (19) (2006) 9352-9355
-
(2006)
Cancer Res
, vol.66
, Issue.October 19
, pp. 9352-9355
-
-
Ding, L.1
Kleer, C.G.2
-
17
-
-
35748937338
-
Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer
-
Yu J., Cao Q., Mehra R., Laxman B., Yu J., Tomlins S.A., Creighton C.J., Dhanasekaran S.M., Shen R., Chen G., et al. Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer. Cancer Cell 12 November (5) (2007) 419-431
-
(2007)
Cancer Cell
, vol.12
, Issue.November 5
, pp. 419-431
-
-
Yu, J.1
Cao, Q.2
Mehra, R.3
Laxman, B.4
Yu, J.5
Tomlins, S.A.6
Creighton, C.J.7
Dhanasekaran, S.M.8
Shen, R.9
Chen, G.10
-
18
-
-
36349017912
-
A polycomb repression signature in metastatic prostate cancer predicts cancer outcome
-
Yu J., Yu J., Rhodes D.R., Tomlins S.A., Cao X., Chen G., Mehra R., Wang X., Ghosh D., Shah R.B., et al. A polycomb repression signature in metastatic prostate cancer predicts cancer outcome. Cancer Res 67 November (22) (2007) 10657-10663
-
(2007)
Cancer Res
, vol.67
, Issue.November 22
, pp. 10657-10663
-
-
Yu, J.1
Yu, J.2
Rhodes, D.R.3
Tomlins, S.A.4
Cao, X.5
Chen, G.6
Mehra, R.7
Wang, X.8
Ghosh, D.9
Shah, R.B.10
-
19
-
-
34247625135
-
Pharmacologic disruption of polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells
-
This work identifies a small molecular, DZNep that appears to interrupt the PRC2 complex responsible for H3K27 methylation. Targeting the PRC2 complex for downregulation, these investigators show that DZNep has anti-cancer effect.
-
Tan J., Yang X., Zhuang L., Jiang X., Chen W., Lee P.L., Karuturi R.K., Tan P.B., Liu E.T., and Yu Q. Pharmacologic disruption of polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells. Genes Dev 21 May (9) (2007) 1050-1063. This work identifies a small molecular, DZNep that appears to interrupt the PRC2 complex responsible for H3K27 methylation. Targeting the PRC2 complex for downregulation, these investigators show that DZNep has anti-cancer effect.
-
(2007)
Genes Dev
, vol.21
, Issue.May 9
, pp. 1050-1063
-
-
Tan, J.1
Yang, X.2
Zhuang, L.3
Jiang, X.4
Chen, W.5
Lee, P.L.6
Karuturi, R.K.7
Tan, P.B.8
Liu, E.T.9
Yu, Q.10
-
20
-
-
44449134715
-
DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications
-
•] showing that the combination of DZNep and an HDAC inhibitor is highly synergistic in inducing apoptosis in cancer cells. This apoptosis is mediated through the downregulation of the WNT pathway through induction of a natural WNT inhibitor, DACT3.
-
•] showing that the combination of DZNep and an HDAC inhibitor is highly synergistic in inducing apoptosis in cancer cells. This apoptosis is mediated through the downregulation of the WNT pathway through induction of a natural WNT inhibitor, DACT3.
-
(2008)
Cancer Cell
, vol.13
, Issue.June 6
, pp. 529-541
-
-
Jiang, X.1
Tan, J.2
Li, J.3
Kivimäe, S.4
Yang, X.5
Zhuang, L.6
Lee, P.L.7
Chan, M.T.8
Stanton, L.W.9
Liu, E.T.10
-
21
-
-
42949083345
-
MicroRNA expression in cytogenetically normal acute myeloid leukemia
-
Marcucci G., Radmacher M.D., Maharry K., Mrózek K., Ruppert A.S., Paschka P., Vukosavljevic T., Whitman S.P., Baldus C.D., and Langer C. MicroRNA expression in cytogenetically normal acute myeloid leukemia. N Engl J Med 358 May (18) (2008) 1919-1928
-
(2008)
N Engl J Med
, vol.358
, Issue.May 18
, pp. 1919-1928
-
-
Marcucci, G.1
Radmacher, M.D.2
Maharry, K.3
Mrózek, K.4
Ruppert, A.S.5
Paschka, P.6
Vukosavljevic, T.7
Whitman, S.P.8
Baldus, C.D.9
Langer, C.10
-
22
-
-
34547458550
-
p53-mediated activation of miRNA34 candidate tumor-suppressor genes
-
Bommer G.T., Gerin I., Feng Y., Kaczorowski A.J., Kuick R., Love R.E., Zhai Y., Giordano T.J., Qin Z.S., Moore B.B., et al. p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr Biol 17 August (15) (2007) 1298-1307
-
(2007)
Curr Biol
, vol.17
, Issue.August 15
, pp. 1298-1307
-
-
Bommer, G.T.1
Gerin, I.2
Feng, Y.3
Kaczorowski, A.J.4
Kuick, R.5
Love, R.E.6
Zhai, Y.7
Giordano, T.J.8
Qin, Z.S.9
Moore, B.B.10
-
23
-
-
34548803950
-
MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
-
Corney D.C., Flesken-Nikitin A., Godwin A.K., Wang W., and Nikitin A.Y. MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res 67 September (18) (2007) 8433-8438
-
(2007)
Cancer Res
, vol.67
, Issue.September 18
, pp. 8433-8438
-
-
Corney, D.C.1
Flesken-Nikitin, A.2
Godwin, A.K.3
Wang, W.4
Nikitin, A.Y.5
-
24
-
-
34249822779
-
Transcriptional activation of miR-34a contributes to p53-mediated apoptosis
-
•] (see below) are among the most complete in their analysis.
-
•] (see below) are among the most complete in their analysis.
-
(2007)
Mol Cell
, vol.26
, Issue.June 5
, pp. 731-743
-
-
Raver-Shapira, N.1
Marciano, E.2
Meiri, E.3
Spector, Y.4
Rosenfeld, N.5
Moskovits, N.6
Bentwich, Z.7
Oren, M.8
-
25
-
-
34848868157
-
Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells
-
Tazawa H., Tsuchiya N., Izumiya M., and Nakagama H. Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells. Proc Natl Acad Sci U S A 104 September (39) (2007) 15472-15477
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.September 39
, pp. 15472-15477
-
-
Tazawa, H.1
Tsuchiya, N.2
Izumiya, M.3
Nakagama, H.4
-
26
-
-
34250868124
-
Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest
-
As noted above.
-
Tarasov V., Jung P., Verdoodt B., Lodygin D., Epanchintsev A., Menssen A., Meister G., and Hermeking H. Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle 6 July (13) (2007) 1586-1593. As noted above.
-
(2007)
Cell Cycle
, vol.6
, Issue.July 13
, pp. 1586-1593
-
-
Tarasov, V.1
Jung, P.2
Verdoodt, B.3
Lodygin, D.4
Epanchintsev, A.5
Menssen, A.6
Meister, G.7
Hermeking, H.8
-
27
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
As noted above.
-
He L., He X., Lim L.P., de Stanchina E., Xuan Z., Liang Y., Xue W., Zender L., Magnus J., Ridzon D., et al. A microRNA component of the p53 tumour suppressor network. Nature 447 June (7148) (2007) 1130-1134. As noted above.
-
(2007)
Nature
, vol.447
, Issue.June 7148
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.P.3
de Stanchina, E.4
Xuan, Z.5
Liang, Y.6
Xue, W.7
Zender, L.8
Magnus, J.9
Ridzon, D.10
-
28
-
-
34249817549
-
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
-
Chang T.C., Wentzel E.A., Kent O.A., Ramachandran K., Mullendore M., Lee K.H., Feldmann G., Yamakuchi M., Ferlito M., Lowenstein C.J., et al. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell 26 June (5) (2007) 745-752
-
(2007)
Mol Cell
, vol.26
, Issue.June 5
, pp. 745-752
-
-
Chang, T.C.1
Wentzel, E.A.2
Kent, O.A.3
Ramachandran, K.4
Mullendore, M.5
Lee, K.H.6
Feldmann, G.7
Yamakuchi, M.8
Ferlito, M.9
Lowenstein, C.J.10
-
29
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
One of the first landmark papers on the comprehensive sequencing of exons in breast and colon cancers. Their results show that mutations are common but appear to be widely distributed.
-
Sjöblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., et al. The consensus coding sequences of human breast and colorectal cancers. Science 314 October (5797) (2006) 268-274. One of the first landmark papers on the comprehensive sequencing of exons in breast and colon cancers. Their results show that mutations are common but appear to be widely distributed.
-
(2006)
Science
, vol.314
, Issue.October 5797
, pp. 268-274
-
-
Sjöblom, T.1
Jones, S.2
Wood, L.D.3
Parsons, D.W.4
Lin, J.5
Barber, T.D.6
Mandelker, D.7
Leary, R.J.8
Ptak, J.9
Silliman, N.10
-
30
-
-
33947101019
-
Patterns of somatic mutation in human cancer genomes
-
This is the second landmark paper describing the sequencing of all kinases in a much larger number of primary cancers and again showed the distributed nature of mutations but identified a number of pathways more frequently mutated than others.
-
Greenman C., Stephens P., Smith R., Dalgliesh G.L., Hunter C., Bignell G., Davies H., Teague J., Butler A., Stevens C., et al. Patterns of somatic mutation in human cancer genomes. Nature 446 March (7132) (2007) 153-158. This is the second landmark paper describing the sequencing of all kinases in a much larger number of primary cancers and again showed the distributed nature of mutations but identified a number of pathways more frequently mutated than others.
-
(2007)
Nature
, vol.446
, Issue.March 7132
, pp. 153-158
-
-
Greenman, C.1
Stephens, P.2
Smith, R.3
Dalgliesh, G.L.4
Hunter, C.5
Bignell, G.6
Davies, H.7
Teague, J.8
Butler, A.9
Stevens, C.10
-
31
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
This is a landmark paper that described the identification of a recurrent fusion transcript that predominates in prostate cancer. Methodologically, it represents an intelligent application of a combination of informatics, molecular biology, and translational sciences to prove the underlying hypothesis.
-
Tomlins S.A., Rhodes D.R., Perner S., Dhanasekaran S.M., Mehra R., Sun X.W., Varambally S., Cao X., Tchinda J., Kuefer R., et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 310 October (5748) (2005) 644-648. This is a landmark paper that described the identification of a recurrent fusion transcript that predominates in prostate cancer. Methodologically, it represents an intelligent application of a combination of informatics, molecular biology, and translational sciences to prove the underlying hypothesis.
-
(2005)
Science
, vol.310
, Issue.October 5748
, pp. 644-648
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Perner, S.3
Dhanasekaran, S.M.4
Mehra, R.5
Sun, X.W.6
Varambally, S.7
Cao, X.8
Tchinda, J.9
Kuefer, R.10
-
32
-
-
34547642493
-
Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
-
••]) that describes the mechanism of activation induced by the various ETS translocations in prostate cancer.
-
••]) that describes the mechanism of activation induced by the various ETS translocations in prostate cancer.
-
(2007)
Nature
, vol.448
, Issue.August 7153
, pp. 595-599
-
-
Tomlins, S.A.1
Laxman, B.2
Dhanasekaran, S.M.3
Helgeson, B.E.4
Cao, X.5
Morris, D.S.6
Menon, A.7
Jing, X.8
Cao, Q.9
Han, B.10
-
33
-
-
34250334695
-
Fusion transcripts and transcribed retrotransposed loci discovered through comprehensive transcriptome analysis using Paired-End diTags (PETs)
-
•]) uses two different strategies to identify putative translocations/rearrangements in cancer cell lines. Taken together, the estimate for high probability fusion transcripts per cell line is between 30 and 100.
-
•]) uses two different strategies to identify putative translocations/rearrangements in cancer cell lines. Taken together, the estimate for high probability fusion transcripts per cell line is between 30 and 100.
-
(2007)
Genome Res
, vol.17
, Issue.June 6
, pp. 828-838
-
-
Ruan, Y.1
Ooi, H.S.2
Choo, S.W.3
Chiu, K.P.4
Zhao, X.D.5
Srinivasan, K.G.6
Yao, F.7
Choo, C.Y.8
Liu, J.9
Ariyaratne, P.10
-
34
-
-
44349191457
-
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing
-
As above.
-
Campbell P.J., Stephens P.J., Pleasance E.D., O'Meara S., Li H., Santarius T., Stebbings L.A., Leroy C., Edkins S., Hardy C., et al. Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing. Nat Genet 40 June (6) (2008) 722-729. As above.
-
(2008)
Nat Genet
, vol.40
, Issue.June 6
, pp. 722-729
-
-
Campbell, P.J.1
Stephens, P.J.2
Pleasance, E.D.3
O'Meara, S.4
Li, H.5
Santarius, T.6
Stebbings, L.A.7
Leroy, C.8
Edkins, S.9
Hardy, C.10
-
35
-
-
34047174559
-
A module of negative feedback regulators defines growth factor signaling
-
Amit I., Citri A., Shay T., Lu Y., Katz M., Zhang F., Tarcic G., Siwak D., Lahad J., and Jacob-Hirsch J. A module of negative feedback regulators defines growth factor signaling. Nat Genet 39 April (4) (2007) 503-512
-
(2007)
Nat Genet
, vol.39
, Issue.April 4
, pp. 503-512
-
-
Amit, I.1
Citri, A.2
Shay, T.3
Lu, Y.4
Katz, M.5
Zhang, F.6
Tarcic, G.7
Siwak, D.8
Lahad, J.9
Jacob-Hirsch, J.10
-
36
-
-
35349024501
-
Network modeling links breast cancer susceptibility and centrosome dysfunction
-
Pujana M.A., Han J.D., Starita L.M., Stevens K.N., Tewari M., Ahn J.S., Rennert G., Moreno V., Kirchhoff T., and Gold B. Network modeling links breast cancer susceptibility and centrosome dysfunction. Nat Genet 39 November (11) (2007) 1338-1349
-
(2007)
Nat Genet
, vol.39
, Issue.November 11
, pp. 1338-1349
-
-
Pujana, M.A.1
Han, J.D.2
Starita, L.M.3
Stevens, K.N.4
Tewari, M.5
Ahn, J.S.6
Rennert, G.7
Moreno, V.8
Kirchhoff, T.9
Gold, B.10
-
37
-
-
33847337318
-
A common coding variant in CASP8 is associated with breast cancer risk
-
Cox A., Dunning A.M., Garcia-Closas M., Balasubramanian S., Reed M.W., Pooley K.A., Scollen S., Baynes C., Ponder B.A., Chanock S., et al. A common coding variant in CASP8 is associated with breast cancer risk. Nat Genet 39 March (3) (2007) 352-358
-
(2007)
Nat Genet
, vol.39
, Issue.March 3
, pp. 352-358
-
-
Cox, A.1
Dunning, A.M.2
Garcia-Closas, M.3
Balasubramanian, S.4
Reed, M.W.5
Pooley, K.A.6
Scollen, S.7
Baynes, C.8
Ponder, B.A.9
Chanock, S.10
-
38
-
-
34250006413
-
Genome-wide association study identifies novel breast cancer susceptibility loci
-
Easton D.F., Pooley K.A., Dunning A.M., Pharoah P.D., Thompson D., Ballinger D.G., Struewing J.P., Morrison J., Field H., Luben R., et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 447 June (7148) (2007) 1087-1093
-
(2007)
Nature
, vol.447
, Issue.June 7148
, pp. 1087-1093
-
-
Easton, D.F.1
Pooley, K.A.2
Dunning, A.M.3
Pharoah, P.D.4
Thompson, D.5
Ballinger, D.G.6
Struewing, J.P.7
Morrison, J.8
Field, H.9
Luben, R.10
-
39
-
-
43249123378
-
Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics
-
Garcia-Closas M., Hall P., Nevanlinna H., Pooley K., Morrison J., Richesson D.A., Bojesen S.E., Nordestgaard B.G., Axelsson C.K., Arias J.I., et al. Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet 4 April (4) (2008) e1000054
-
(2008)
PLoS Genet
, vol.4
, Issue.April 4
-
-
Garcia-Closas, M.1
Hall, P.2
Nevanlinna, H.3
Pooley, K.4
Morrison, J.5
Richesson, D.A.6
Bojesen, S.E.7
Nordestgaard, B.G.8
Axelsson, C.K.9
Arias, J.I.10
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