메뉴 건너뛰기




Volumn 327, Issue 1, 2008, Pages 178-186

Calcium sensitization in human esophageal muscle: Role for RhoA kinase in maintenance of lower esophageal sphincter tone

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CALCIUM ION; CARBACHOL; FASUDIL; FURA 2; NITRIC OXIDE; PROTEIN KINASE C INHIBITOR; RHO KINASE; RHO KINASE INHIBITOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA KINASE; RHOA KINASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 52649142167     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.140806     Document Type: Article
Times cited : (23)

References (40)
  • 1
    • 0033227234 scopus 로고    scopus 로고
    • Review article: Pharmacological options in achalasia
    • Bassotti G and Annese V (1999) Review article: pharmacological options in achalasia. Aliment Pharmacol Ther 13:1391-1396.
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 1391-1396
    • Bassotti, G.1    Annese, V.2
  • 2
    • 0019353185 scopus 로고
    • Clinical and manometric effects of nifedipine in patients with esophageal achalasia
    • Bortolotti M and Labò G (1981) Clinical and manometric effects of nifedipine in patients with esophageal achalasia. Gastroenterology 80:39-44.
    • (1981) Gastroenterology , vol.80 , pp. 39-44
    • Bortolotti, M.1    Labò, G.2
  • 3
    • 0033230312 scopus 로고    scopus 로고
    • The relationship between the action potential, intracellular calcium and force in intact phasic, guinea-pig uretic smooth muscle
    • Burdyga TV and Wray S (1999) The relationship between the action potential, intracellular calcium and force in intact phasic, guinea-pig uretic smooth muscle. J Physiol 520:867-883.
    • (1999) J Physiol , vol.520 , pp. 867-883
    • Burdyga, T.V.1    Wray, S.2
  • 5
    • 0020563985 scopus 로고
    • Differences between esophageal body and lower esophageal sphincter in mitochondria of smooth muscle in opossum
    • Christensen J and Roberts RL (1983) Differences between esophageal body and lower esophageal sphincter in mitochondria of smooth muscle in opossum. Gastroenterology 85:650-656.
    • (1983) Gastroenterology , vol.85 , pp. 650-656
    • Christensen, J.1    Roberts, R.L.2
  • 6
    • 0036260894 scopus 로고    scopus 로고
    • Roles of guanylate cyclase in responses to myogenic and neural nitric oxide in canine lower esophageal sphincter
    • Daniel EE, Bowes TJ, and Jury J (2002) Roles of guanylate cyclase in responses to myogenic and neural nitric oxide in canine lower esophageal sphincter. J Pharmacol Exp Ther 301:1111-1118.
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 1111-1118
    • Daniel, E.E.1    Bowes, T.J.2    Jury, J.3
  • 7
    • 0036103111 scopus 로고    scopus 로고
    • Effect of sildenafil on oesophageal motor function in healthy subjects and patients with oesophageal motor disorders
    • Eherer AJ, Schwetz I, Hammer HF, Petnehazy T, Scheidl SJ, Weber K, and Krejs GJ (2002) Effect of sildenafil on oesophageal motor function in healthy subjects and patients with oesophageal motor disorders. Gut 50:758-764.
    • (2002) Gut , vol.50 , pp. 758-764
    • Eherer, A.J.1    Schwetz, I.2    Hammer, H.F.3    Petnehazy, T.4    Scheidl, S.J.5    Weber, K.6    Krejs, G.J.7
  • 8
    • 40149092968 scopus 로고    scopus 로고
    • Regulation of basal tone, relaxation and contraction of the lower oesophageal sphincter. Relevance to drug discovery for oesophageal disorders
    • Farré R and Sifrim D (2008) Regulation of basal tone, relaxation and contraction of the lower oesophageal sphincter. Relevance to drug discovery for oesophageal disorders. Br J Pharmacol 153:858-869.
    • (2008) Br J Pharmacol , vol.153 , pp. 858-869
    • Farré, R.1    Sifrim, D.2
  • 9
    • 17744377218 scopus 로고    scopus 로고
    • Signal-transduction pathways that regulate visceral smooth muscle function. III. Coupling of muscarinic receptors to signaling kinases and effector proteins in gastrointestinal smooth muscles
    • Gerthoffer WT (2005) Signal-transduction pathways that regulate visceral smooth muscle function. III. Coupling of muscarinic receptors to signaling kinases and effector proteins in gastrointestinal smooth muscles. Am J Physiol Gastrointest Liver Physiol 288:G849-G853.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.288
    • Gerthoffer, W.T.1
  • 10
    • 17644405456 scopus 로고    scopus 로고
    • Effects of Rho kinase inhibition on cerebral artery myogenic tone and reactivity
    • Gokina NI, Park KM, McElroy-Yaggy K, and Osol G (2005) Effects of Rho kinase inhibition on cerebral artery myogenic tone and reactivity. J Appl Physiol 98:1940-1948.
    • (2005) J Appl Physiol , vol.98 , pp. 1940-1948
    • Gokina, N.I.1    Park, K.M.2    McElroy-Yaggy, K.3    Osol, G.4
  • 11
    • 42449095597 scopus 로고    scopus 로고
    • Physiology of normal esophageal motility
    • Goyal RK and Chaudhury A (2008) Physiology of normal esophageal motility. J Clin Gastroenterol 42:610-619.
    • (2008) J Clin Gastroenterol , vol.42 , pp. 610-619
    • Goyal, R.K.1    Chaudhury, A.2
  • 12
    • 13944277401 scopus 로고    scopus 로고
    • Signal-transduction pathways that regulate smooth muscle function I. Signal transduction in phasic (esophageal) and tonic (gastroesophageal sphincter) smooth muscles
    • Harnett KM, Cao W, and Biancani P (2005) Signal-transduction pathways that regulate smooth muscle function I. Signal transduction in phasic (esophageal) and tonic (gastroesophageal sphincter) smooth muscles. Am J Physiol Gastrointest Liver Physiol 288:G407-G416.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.288
    • Harnett, K.M.1    Cao, W.2    Biancani, P.3
  • 13
    • 0021273065 scopus 로고
    • Comparison of effects of nifedipine, propantheline bromide, and the combination on esophageal motor function in normal volunteers
    • Hongo M, Traube M, and McCallum RW (1984) Comparison of effects of nifedipine, propantheline bromide, and the combination on esophageal motor function in normal volunteers. Dig Dis Sci 29:300-304.
    • (1984) Dig Dis Sci , vol.29 , pp. 300-304
    • Hongo, M.1    Traube, M.2    McCallum, R.W.3
  • 14
    • 33745937484 scopus 로고    scopus 로고
    • Tachykinin receptor expression and function in human esophageal smooth muscle
    • Kovac JR, Chrones T, Preiksaitis HG, and Sims SM (2006) Tachykinin receptor expression and function in human esophageal smooth muscle. J Pharmacol Exp Ther 318:513-520.
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 513-520
    • Kovac, J.R.1    Chrones, T.2    Preiksaitis, H.G.3    Sims, S.M.4
  • 15
    • 28444483951 scopus 로고    scopus 로고
    • Functional and molecular analysis of L-type calcium channels in human esophagus and lower esophageal sphincter smooth muscle
    • Kovac JR, Preiksaitis HG, and Sims SM (2005) Functional and molecular analysis of L-type calcium channels in human esophagus and lower esophageal sphincter smooth muscle. Am J Physiol Gastrointest Liver Physiol 289:G998-G1006.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.289
    • Kovac, J.R.1    Preiksaitis, H.G.2    Sims, S.M.3
  • 16
    • 0035171680 scopus 로고    scopus 로고
    • Tachykinins contribute to nerve-mediated contractions in the human esophagus
    • Krysiak PS and Preiksaitis HG (2001) Tachykinins contribute to nerve-mediated contractions in the human esophagus. Gastroenterology 120:39-48.
    • (2001) Gastroenterology , vol.120 , pp. 39-48
    • Krysiak, P.S.1    Preiksaitis, H.G.2
  • 19
    • 33645957353 scopus 로고    scopus 로고
    • Signaling for contraction and relaxation in smooth muscle of the gut
    • Murthy KS (2006) Signaling for contraction and relaxation in smooth muscle of the gut. Annu Rev Physiol 68:345-374.
    • (2006) Annu Rev Physiol , vol.68 , pp. 345-374
    • Murthy, K.S.1
  • 20
    • 0029070896 scopus 로고
    • Phasic contractions of the muscular components of human esophagus and gastroesophageal junction in vitro
    • Preiksaitis HG and Diamant NE (1995) Phasic contractions of the muscular components of human esophagus and gastroesophageal junction in vitro. Can J Physiol Pharmacol 73:356-363.
    • (1995) Can J Physiol Pharmacol , vol.73 , pp. 356-363
    • Preiksaitis, H.G.1    Diamant, N.E.2
  • 21
    • 0030843212 scopus 로고    scopus 로고
    • Regional differences in cholinergic activity of muscle fibers from the human gastroesophageal junction
    • Preiksaitis HG and Diamant NE (1997) Regional differences in cholinergic activity of muscle fibers from the human gastroesophageal junction. Am J Physiol Gastrointest Liver Physiol 272:G1321-G1327.
    • (1997) Am J Physiol Gastrointest Liver Physiol , vol.272
    • Preiksaitis, H.G.1    Diamant, N.E.2
  • 22
    • 0033724845 scopus 로고    scopus 로고
    • Pharmacological and molecular characterization of muscarinic receptor subtypes in human esophageal smooth muscle
    • Preiksaitis HG, Krysiak PS, Chrones T, Rajgopal V, and Laurier LG (2000) Pharmacological and molecular characterization of muscarinic receptor subtypes in human esophageal smooth muscle. J Pharmacol Exp Ther 295:879-888.
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 879-888
    • Preiksaitis, H.G.1    Krysiak, P.S.2    Chrones, T.3    Rajgopal, V.4    Laurier, L.G.5
  • 23
    • 0028203516 scopus 로고
    • Nitric oxide mediates inhibitory nerve effects in human esophagus and lower esophageal sphincter
    • Preiksaitis HG, Tremblay L, and Diamant NE (1994) Nitric oxide mediates inhibitory nerve effects in human esophagus and lower esophageal sphincter. Dig Dis Sci 39:770-775.
    • (1994) Dig Dis Sci , vol.39 , pp. 770-775
    • Preiksaitis, H.G.1    Tremblay, L.2    Diamant, N.E.3
  • 24
    • 0141625006 scopus 로고    scopus 로고
    • Involvement of rho and rho-associated kinase in sphincteric smooth muscle contraction by angiotensin II
    • Rattan S, Puri RN, and Fan YP (2003) Involvement of rho and rho-associated kinase in sphincteric smooth muscle contraction by angiotensin II. Exp Biol Med (Maywood) 228:972-981.
    • (2003) Exp Biol Med (Maywood) , vol.228 , pp. 972-981
    • Rattan, S.1    Puri, R.N.2    Fan, Y.P.3
  • 25
    • 15444368647 scopus 로고    scopus 로고
    • Regulation of smooth muscle calcium sensitivity: KCl as a calcium-sensitizing stimulus
    • Ratz PH, Berg KM, Urban NH, and Miner AS (2005) Regulation of smooth muscle calcium sensitivity: KCl as a calcium-sensitizing stimulus. Am J Physiol Cell Physiol 288:C769-C783.
    • (2005) Am J Physiol Cell Physiol , vol.288
    • Ratz, P.H.1    Berg, K.M.2    Urban, N.H.3    Miner, A.S.4
  • 26
    • 0032453955 scopus 로고    scopus 로고
    • Calcium source diversity in canine lower esophageal sphincter muscle
    • Salapatek AM, Lam A, and Daniel EE (1998) Calcium source diversity in canine lower esophageal sphincter muscle. J Pharmacol Exp Ther 287:98-106.
    • (1998) J Pharmacol Exp Ther , vol.287 , pp. 98-106
    • Salapatek, A.M.1    Lam, A.2    Daniel, E.E.3
  • 28
    • 0030693721 scopus 로고    scopus 로고
    • Regulation of intracellular calcium in human esophageal smooth muscles
    • Sims SM, Jiao Y, and Preiksaitis HG (1997) Regulation of intracellular calcium in human esophageal smooth muscles. Am J Physiol Cell Physiol 273:C1679-C1689.
    • (1997) Am J Physiol Cell Physiol , vol.273
    • Sims, S.M.1    Jiao, Y.2    Preiksaitis, H.G.3
  • 29
    • 0028043535 scopus 로고
    • Signal transduction and regulation in smooth muscle
    • Somlyo AP and Somlyo AV (1994) Signal transduction and regulation in smooth muscle. Nature 372:231-236.
    • (1994) Nature , vol.372 , pp. 231-236
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 30
    • 0141751697 scopus 로고    scopus 로고
    • 2+ sensitivity of smooth muscle and nonmuscle myosin II: Modulated by G proteins, kinases, and myosin phosphatase
    • 2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev 83:1325-1358.
    • (2003) Physiol Rev , vol.83 , pp. 1325-1358
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 31
    • 0031668167 scopus 로고    scopus 로고
    • Differences in contractile protein content and isoforms in phasic and tonic smooth muscles
    • Szymanski PT, Chacko TK, Rovner AS, and Goyal RK (1998) Differences in contractile protein content and isoforms in phasic and tonic smooth muscles. Am J Physiol Cell Physiol 275:C684-C692.
    • (1998) Am J Physiol Cell Physiol , vol.275
    • Szymanski, P.T.1    Chacko, T.K.2    Rovner, A.S.3    Goyal, R.K.4
  • 32
    • 0036079265 scopus 로고    scopus 로고
    • Differences in calmodulin and calmodulin-binding proteins in phasic and tonic smooth muscles
    • Szymanski PT, Szymanska G, and Goyal RK (2002) Differences in calmodulin and calmodulin-binding proteins in phasic and tonic smooth muscles. Am J Physiol Cell Physiol 282:C94-C104.
    • (2002) Am J Physiol Cell Physiol , vol.282
    • Szymanski, P.T.1    Szymanska, G.2    Goyal, R.K.3
  • 33
    • 0033603660 scopus 로고    scopus 로고
    • Cellular redistribution of PKCα, RhoA, and ROKα following smooth muscle agonist stimulation
    • Taggart MJ, Lee YH, and Morgan KG (1999) Cellular redistribution of PKCα, RhoA, and ROKα following smooth muscle agonist stimulation. Exp Cell Res 251:92-101.
    • (1999) Exp Cell Res , vol.251 , pp. 92-101
    • Taggart, M.J.1    Lee, Y.H.2    Morgan, K.G.3
  • 35
    • 0021228098 scopus 로고
    • Effects of nifedipine in achalasia and in patients with high-amplitude peristaltic esophageal contractions
    • Traube M, Hongo M, Magyar L, and McCallum RW (1984) Effects of nifedipine in achalasia and in patients with high-amplitude peristaltic esophageal contractions. J Am Med Assoc 252:1733-1736.
    • (1984) J Am Med Assoc , vol.252 , pp. 1733-1736
    • Traube, M.1    Hongo, M.2    Magyar, L.3    McCallum, R.W.4
  • 39
    • 24644479674 scopus 로고    scopus 로고
    • Calcium signalling in smooth muscle
    • Wray S, Burdyga T, and Noble K (2005) Calcium signalling in smooth muscle. Cell Calcium 38:397-407.
    • (2005) Cell Calcium , vol.38 , pp. 397-407
    • Wray, S.1    Burdyga, T.2    Noble, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.