Failure of adrenal corticosterone production in POMC-deficient mice results from lack of integrated effects of POMC peptides on multiple factors

American Journal of Physiology - Endocrinology and Metabolism

Volumn 295, Issue 2, 2008, Pages

  Karpac, Jason ^a   Czyzewska, Katarzyna ^a   Kern, Andras ^a   Brush, Richard S ^b   Anderson, Robert E ^b   Hochgeschwender, Ute ^a,c  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Adrenocorticotropic hormone; Cholesterol; Gene expression; Proopiomelanocortin; Scavenger receptor class B, type I

Indexed keywords

CHOLESTEROL; CHOLESTEROL ESTER; CORTICOSTERONE; CORTICOTROPIN; PROOPIOMELANOCORTIN; CHOLESTEROL ESTERASE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE (NADPH); PHOSPHOPROTEIN; RNA; SCARB1 PROTEIN, MOUSE; SCAVENGER RECEPTOR B; STEROIDOGENIC ACUTE REGULATORY PROTEIN;

ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL METABOLISM; FEMALE; HORMONE ACTION; HORMONE DEFICIENCY; HORMONE SYNTHESIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEROIDOGENESIS; ANIMAL; BIOSYNTHESIS; CHEMISTRY; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADRENAL GLANDS; ADRENOCORTICOTROPIC HORMONE; ANIMALS; BLOTTING, WESTERN; CHOLESTEROL; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CORTICOSTERONE; FEMALE; HYDROXYMETHYLGLUTARYL-COA-REDUCTASES, NADP-DEPENDENT; MALE; MICE; MICE, KNOCKOUT; PHOSPHOPROTEINS; PRO-OPIOMELANOCORTIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SCAVENGER RECEPTORS, CLASS B; STEROL ESTERASE; TRANSCRIPTION, GENETIC;

EID: 52649131350     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00762.2007     Document Type: Article

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