Investigations with O-linked protein glycosylations by matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry

Journal of Mass Spectrometry

Volumn 43, Issue 9, 2008, Pages 1215-1223

  Williams, Taufika Islam ^a   Saggese, Diana A ^a   Toups, Kristina L ^a   Frahm, Jennifer L ^a   An, Hyun Joo ^b   Li, Bensheng ^b   Lebrilla, Carlito B ^b   Muddiman, David C ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Fourier transform ion cyclotron mass spectrometry (FT ICR MS); Matrix assisted laser desorption ionization (MALDI); Mucin; O linked glycans; Protein glycosylations

Indexed keywords

BIOMOLECULES; CARBOHYDRATES; CYCLOTRON RESONANCE; CYCLOTRONS; DESORPTION; ELECTRON CYCLOTRON RESONANCE; EXPERIMENTS; GLYCOPROTEINS; HEALTH; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONS; ISOTOPES; LASERS; MAGNETISM; MASS SPECTROMETERS; MASS SPECTROMETRY; MATRIX ALGEBRA; MOLECULAR BIOLOGY; OPTIMIZATION; ORGANIC COMPOUNDS; PARTICLE ACCELERATORS; PLASMAS; RESONANCE; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS;

ACQUISITION TIMES; ANALYTE; COMPREHENSIVE ANALYSIS; EARLY DETECTION; EXCITATION VOLTAGES; EXPERIMENTAL PARAMETERS; FOURIER TRANSFORM ION CYCLOTRON MASS SPECTROMETRY (FT-ICR-MS); FOURIER TRANSFORM ION CYCLOTRON RESONANCE MASS SPECTROMETRY; GLYCANS; GLYCOSYLATIONS; ION GUIDING; MATRIX-ASSISTED LASER DESORPTION/IONIZATION; MATRIX-ASSISTED LASER DESORPTION/IONIZATION (MALDI); MUCIN; O-LINKED; O-LINKED GLYCANS; OPTIMIZATION STUDIES; OVARIAN CANCERS; POST-TRANSLATIONAL MODIFICATIONS; PROTEIN GLYCOSYLATIONS; QUADRUPOLE; SAMPLE PREPARATION TECHNIQUES; SAMPLE PREPARATIONS; SIGNALING PATHWAYS; SMALL VARIATIONS; STABLE ISOTOPES;

FOURIER TRANSFORMS;

ANGIOTENSIN I; BIOLOGICAL MARKER; CARBOHYDRATE; CARBON 13; DISACCHARIDE; GLYCAN; GLYCOPROTEIN; ISOTOPE; MUCIN; OLIGOSACCHARIDE; SUCROSE;

ARTICLE; CARBOHYDRATE ANALYSIS; DISEASE MARKER; FOURIER TRANSFORMATION; ION CYCLOTRON RESONANCE MASS SPECTROMETRY; ISOTOPE LABELING; MASS SPECTROMETER; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN PROCESSING; STOMACH; SWINE;

ANGIOTENSINS; ANIMALS; GLYCOSYLATION; MUCINS; OLIGOSACCHARIDES; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SWINE; TANDEM MASS SPECTROMETRY;

EID: 52649128244     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1398     Document Type: Article

References (47)

1. Williams TI, Toups KL, Saggese DA, Kalli KR; Cliby WA, Muddiman DC. Epithelial ovarian cancer: disease etiology, treatment, detection, and investigational gene, metabolite, and protein biomarkers. Journal ofProteome Research 2007;6: 2936.
2. Dennis JW, Granovsky M, Warren CE. Glycoprotein glycosyla-tion and cancer progression. Biochimica et Biophysica Acta 1999;1473: 21.
3. Dennis JW, Granovsky M, Warren CE. Protein glycosylation in development and disease. Bioessays 1999;21: 412.
4. Aranganathan S, Senthil K, Nalini N. A case control study of glycoprotein status in ovarian carcinoma. Clinical Biochemistry 2005;38: 535.
5. Casey RC, Oegema TR Jr, Skubitz KM, Pambuccian SE, Grindle SM, Skubitz AP. Cell membrane glycosylation mediates the adhesion, migration, and invasion of ovarian carcinoma cells. Clinical and Experimental Metastasis 2003;20: 143.
6. Dwek MV, Brooks SA. Harnessing changes in cellular glycosylation in new cancer treatment strategies. Current Cancer Drug Targets 2004;4: 425.
7. Yang Z, Hancock WS. Approach to the comprehensive analysis of glycoproteins isolated from human serum using a multi-lectin affinity column. Journal of Chromatography. A 2004;1053: 79.
8. Madera M, Mechref Y, Klouckova I, Novotny MV. High-sensitivity profiling of glycoproteins from human blood serum through multiple-lectin affinity chromatography and liquid chromatography/tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and life Sciences 2007;845: 121.
9. Guo JM, Zhang XY, Chen HL, Wang GM, Zhang YK. Structural alterations of sugar chains in urine fibronectin from bladder cancer patients and its enzymatic mechanism. Journal of Cancer Research and Clinical Oncology 2001;127: 512.
10. Valmu L, Alfthan H, Hotakainen K, Birken S, Stenman UH. Site-specific glycan analysis of human chorionic gonadotropin beta-subunit from malignancies and pregnancy by liquid chromatography-electrospray mass spectrometry. Glycobiology 2006;16: 1207.
11. Rudd PM, Mattu TS, Masure S, Bratt T, Van den Steen PE, Wormald MR, Kuster B, Harvey DJ, Borregaard N, Van Damme J, Dwek RA, Opdenakker G. Glycosylation of natural human neutrophil gelatinase B and neutrophil gelatinase B-associated lipocalin. Biochemistry 1999;38: 13937.
12. Veenstra TD, Conrads TP, Hood BL, Avellino AM, Ellenbo-gen RG, Morrison RS. Biomarkers: mining the biofluid proteome. Molecular and Cellular Proteomics 2005;4: 409.
13. Fraser-Reid BO, Tatsuta K, Thiem J (eds). Glycoscience. Springer-Verlag, Berlin Heidelberg: Berlin, 2001.
14. Zhang XL. Roles of glycans and glycopeptides in immune system and immune-related diseases. Current Medicinal Chemistry 2006;13:1141.
15. Rudd PM, Elliott T, Cresswell P, Wilson IA, Dwek RA. Glycosylation and the immune system. Science 2001;291: 2370.
16. Lloyd KO, Burchell J, Kudryashov V, Yin BW, Taylor-Papadimitriou J. Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells. The journal of Biological Chemistry 1996;271: 33 325.
17. Colpitts TL, Billing P, Granados E, Hayden M, Hodges S, Roberts L, Russell J, Friedman P, Stroupe S. Identification and immunohistochemical characterization of a mucin-like glycoprotein expressed in early stage breast carcinoma. Tumour Biology 2002;23: 263.
18. Baldus SE, Wienand JR, Werner JP, Landsberg S, Drebber U, Hanisch FG, Dienes HP. Expression of MUC1, MUC2 and oligosaccharide epitopes in breast cancer: prognostic significance of a sialylated MUC1 epitope. International Journal of Oncology 2005;27: 1289.
19. Berois N, Mazal D, Ubillos L, Trajtenberg F, Nicolas A, Sastre-Garau X, Magdelenat H, Osinaga E. UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase-6 as a new immunohistochemical breast cancer marker. The journal ofHistochemistry and Cytochemistry 2006;54: 317.
20. Kirmiz C, LiB, An HJ, Clowers BH, Chew HK, Lam KS, Ferrige A, Alecio R, Borowsky AD, Sulaimon S, Lebrilla CB, Miyamoto S. A serum glycomics approach to breast cancer biomarkers. Molecular and Cellular Proteomics 2007;6: 43.
21. An HJ, Miyamoto S, Lancaster KS, Kirmiz C, Li B, Lam KS, Leiserowitz GS, Lebrilla CB. Profiling of glycans in serum for the discovery of potential biomarkers for ovarian cancer. Journal ofProteome Research 2006;5: 1626.
22. Nagata A, Hirota N, Sakai T, Fujimoto M, Komoda T. Molecular nature and possible presence of a membranous glycan-phosphatidylinositol anchor of CA125 antigen. Tumour Biology 1991;12: 279.
23. Hsu YT, Hou Q, Zhou H, Mohanty S, Litvinchuk A. Differential immunoscreening identifies a glycosylation variant of the epidermal growth factor receptor in ME-180 cervical carcinoma cells. Hybridoma (Larchmt) 2005;24: 225.
24. Carlson DM. Oligosaccharides isolated from pig submaxillary mucin. The Journal of Biological Chemistry 1966;241: 2984.
25. Nordman H, Davies JR, Carlstedt I. Mucus glycoproteins from pig gastric mucosa: different mucins are produced by the surface epithelium and the glands. The Biochemical Journal 1998;331: 687.
26. Karlsson NG, Packer NH. Analysis of O-linked reducing oligosaccharides released by an in-line flow system. Analytical Biochemistry 2002;305:173.
27. Iwase H, Ishii-Karakasa I, Hotta K. Isolation and partial characterization of serine- and threonine-rich porcine gastric mucus glycopeptides. Comparative Biochemistry and Physiology 1992;102B: 929.
28. Chai W, Feizi T, Yuen CT, Lawson AM. Nonreductive release of O-linked oligosaccharides from mucin glycoproteins for structure/function assignments as neoglycolipids: application in the detection of novel ligands for E-selectin. Glycobioiogy 1997;7:861.
29. Thomsson KA, Karlsson H, Hansson GC. Sequencing of sulfated oligosaccharides from mucins by liquid chromatography and electrospray ionization tandem mass spectrometry. Analytical Chemistry 2000;72: 4543.
30. Thomsson KA, Karlsson NG, Hansson GC. Liquid chromatography-electrospray mass spectrometry as a tool for the analysis of sulfated oligosaccharides from mucin glycoproteins. Journal of Chromatography. A 1999;854: 131.
31. Slomiany BL, Meyer K. Isolation and structural studies of sulfated glycoproteins of hog gastric mucosa. The Journal of Biological Chemistry 1972;247: 5062.
32. Van HalbeekH, Dorland L, Veldink GA, Vliegenthart JF, Garegg PJ, Norberg T, Lindberg B. A 500-MHz proton-magnetic-resonance study of several fragments of the carbohydrate-protein linkage region commonly occurring in proteoglycans. European Journal of Biochemistry 1982;127: 1.
33. Zenteno E, Vazquez L, Chavez R, Cordoba F, Wieruszeski JM, Montreuil J, Debray H. Specificity of the isolectins from the lant cactus Machaerocereus eruca for oligosaccharides from porcine stomach mucin. Glycoconjugate Journal 1995;12: 699.
34. Williams TI, Saggese DA, Wilcox RJ, Martin JD, Muddiman DC. Effect of matrix crystal structure on ion abundance of carbohydrates by matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry. Rapid Communications in Mass Spectrometry 2007;21: 807.
35. Pan CS, Xu SY, Zhou HJ, Fu Y, Ye ML, Zou HF. Recent developments in methods and technology for analysis of biological samples by MALDI-TOF-MS. Analytical and Bioanalytical Chemistry 2007;387:193.
36. Harvey DJ. Matrix-assisted laser desorption ionisation mass spectrometry of oligosaccharides and glycoconjugates. Journal of Chromatography. A 1996;720: 429.
37. Gusev AI, Wilkinson WR, Proctor A, Hercules DM. Improvement of signal reproducibility and matrix/comatrix effects in Maldi analysis. Analytical Chemistry 1995;67: 1034.
38. Frahm JL, Velez CM, Muddiman DC. Understanding the influence of post-excite radius and axial confinement on quantitative proteomic measurements using Fourier transform ion cyclotron resonance mass spectrometry. Rapid Communications in Mass Spectrometry 2007;21:1196.
39. Chen L, Wang TC, Ricca TL, Marshall AG. Phase-modulated stored waveform inverse Fourier transform excitation for trapped ion mass spectrometry. Analytical Chemistry 1987;59: 449.
40. Iyer RN, Carlson DM. Alkaline borohydride degradation of blood group H substance. Archives of Biochemistry and Biophysics 1971;142: 101.
41. Hawkridge AM, Nepomuceno AI, Lovik SL, Mason CJ, Muddiman DC. Effect of post-excitation radius on ion abundance, mass measurement accuracy, and isotopic distributions in Fourier transform ion cyclotron resonance mass spectrometry. Rapid Communications in Mass Spectrometry 2005;19: 915.
42. Packer NH, Lawson MA, Jardine DR, Redmond JW. A general approach to desalting oligosaccharides released from glycoproteins. Glycoconjugate Journal 1998;15: 737.
43. Sze TPE, Chan TWD. Time-of-flight effects in matrix-assisted laser desorption/ionization Fourier transform mass spectrometry. Rapid Communications in Mass Spectrometry 1999;13: 398.
44. An HJ, Tillinghast JS, Woodruff DL, Rocke DM, Lebrilla CB. A new computer program (GlycoX) to determine simultaneously the glycosylation sites and oligosaccharide heterogeneity of glycoproteins. Journal of Proteome Research 2006;5: 2800.
45. Murray RK. Glycoproteins: crucial molecules for health. GlycoScience and Nutrition 2003;4: 1.
46. Cohen DE, Benedict JB, Morlan B, Chiu DT, Kahr B. Dyeing Polymorphs: the MALDI Host 2,5-Dihydroxybenzoic Acid. Crystal Growth and Design 2007;7:492.
47. Bereman MS, Williams TI, Muddiman DC. Carbohydrate analysis by desorption electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. Analytical Chemistry 2007;79: 8812.