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Volumn 27, Issue 4, 2008, Pages 277-280

Potential for metabolism locally in the skin of dermally absorbed compounds

Author keywords

Absorption; Dermal; Metabolism

Indexed keywords

4 HYDROXYBENZOIC ACID ESTER; ACETIC ACID; ALCOHOL; BUTOXYACETIC ACID; BUTOXYETHANOL; CHEMICAL AGENT; HYDROXYBENZOIC ACID; UNCLASSIFIED DRUG; ALCOHOL DEHYDROGENASE; CARBOXYLESTERASE; ETHYLENE GLYCOL DERIVATIVE; N BUTOXYETHANOL; N-BUTOXYETHANOL;

EID: 52649103468     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327107085831     Document Type: Article
Times cited : (15)

References (16)
  • 1
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    • Lee FW Earl L Williams FM. Inter individual variability in percutaneous penetration of testosterone through human skin in vitro. Toxicology 2001 ; 168: 63.
    • (2001) Toxicology , vol.168 , pp. 63
    • Lee, F.W.1    Earl, L.2    Williams, F.M.3
  • 2
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    • Significance of metabolism occurring locally in the skin for dermally absorbed compounds.
    • Williams FM. Significance of metabolism occurring locally in the skin for dermally absorbed compounds. Toxicol Lett 2006 ; 164 (Suppl.): S322-S323.
    • (2006) Toxicol Lett , vol.164
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  • 3
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    • The metabolism of cypermethrin in man: Differences in urinary profiles following oral and dermal administration.
    • Woollen BH Marsh JR Laird WJ Lesser JE. The metabolism of cypermethrin in man: differences in urinary profiles following oral and dermal administration. Xenobiotica 1992 ; 22: 983-991.
    • (1992) Xenobiotica , vol.22 , pp. 983-991
    • Woollen, B.H.1    Marsh, J.R.2    Laird, W.J.3    Lesser, J.E.4
  • 4
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    • Wilkinson SC Williams FM. Cutaneous metabolism. In: Walter, K, Roberts, M, (eds), Dermal absorption and toxicity assessment. 2007. Roberts, MS, Walters, KE, (eds), 2nd edition, New York: Informa Healthcare; 2008. p. 89-115.
    • (2007) , pp. 89-115
    • Wilkinson, S.C.1    Williams, F.M.2
  • 6
    • 36049029705 scopus 로고    scopus 로고
    • Hydrolysis of a series of paraben esters by skin sub-cellular fractions and in short-term culture from human and minipigs.
    • Jewell C Ackermann C Payne NA Fate G Voorman R Williams FM. Hydrolysis of a series of paraben esters by skin sub-cellular fractions and in short-term culture from human and minipigs. Toxicol Appl Pharm 2007 ; 225: 221-228.
    • (2007) Toxicol Appl Pharm , pp. 221-228
    • Jewell, C.1    Ackermann, C.2    Payne, N.A.3    Fate, G.4    Voorman, R.5    Williams, F.M.6
  • 9
    • 72849129027 scopus 로고    scopus 로고
    • The effect of in vitro receptor media on the percutaneous absorption of methyl paraben.
    • Wilkinson R Jewell C Wilkinson SC Williams FM Blain PG. The effect of in vitro receptor media on the percutaneous absorption of methyl paraben. Toxicology 2007 ; 240: 178-179.
    • (2007) Toxicology , pp. 178-179
    • Wilkinson, R.1    Jewell, C.2    Wilkinson, S.C.3    Williams, F.M.4    Blain, P.G.5
  • 10
    • 13644271259 scopus 로고    scopus 로고
    • Free and total urinary 2-butoxyacetic acid following dermal and inhalation exposure to 2-butoxyethanol in human volunteers.
    • Kezic S Meuling WJ Jakasa I. Free and total urinary 2-butoxyacetic acid following dermal and inhalation exposure to 2-butoxyethanol in human volunteers. Int Arch Occup Environ Health 2004 ; 77: 580-586.
    • (2004) Int Arch Occup Environ Health , vol.77 , pp. 580-586
    • Kezic, S.1    Meuling, W.J.2    Jakasa, I.3
  • 11
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    • Percutaneous penetration and metabolism of butoxyethanol.
    • Lockley DJ Howes D Williams FM. Percutaneous penetration and metabolism of butoxyethanol. Arch Toxicol 2004 ; 78: 617-629.
    • (2004) Arch Toxicol , vol.78 , pp. 617-629
    • Lockley, D.J.1    Howes, D.2    Williams, F.M.3
  • 12
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    • Williams FM Traynor MJ Wakefield JC Dunn M. Metabolism of absorbed chemicals by skin in short term culture. Prediction of Percutaneous Penetration Conference. La Grand Motte; 2006 [abstract].
    • Williams, F.M.1    Traynor, M.J.2    Wakefield, J.C.3    Dunn, M.4
  • 13
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    • Percutaneous absorption of neat and aqueous solutions of butoxyethanol in volunteers.
    • Jakasa Y Mohammedi N Kruse J Kezic S. Percutaneous absorption of neat and aqueous solutions of butoxyethanol in volunteers. Int Arch Occup Environ Health 2004 ; 77: 79-84.
    • (2004) Int Arch Occup Environ Health , vol.77 , pp. 79-84
    • Jakasa, Y.1    Mohammedi, N.2    Kruse, J.3    Kezic, S.4
  • 16
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    • In vitro studies-how good are they at replacing in vivo studies for measurement of skin absorption?
    • Williams FM. In vitro studies-how good are they at replacing in vivo studies for measurement of skin absorption? Environ Toxicol Pharmacol 2006 ; 21: 199-203.
    • (2006) Environ Toxicol Pharmacol , vol.21 , pp. 199-203
    • Williams, F.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.