7-epiclusianone, a tetraprenylated benzophenone, relaxes airway smooth muscle through activation of the nitric oxide-cGMP pathway

Journal of Pharmacology and Experimental Therapeutics

Volumn 327, Issue 1, 2008, Pages 206-214

  Coelho, Luciana Pontes ^a   Serra, Magda Fráguas ^a   Pires, Ana Lúcia De Aguiar ^a   Cordeiro, Renato Sérgio Balão ^a   Silva, Patrícia Machado Rodrigues ^a   Dos Santos, Marcelo Henrique ^b   Martins, Marco Aurélio ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF ALFENAS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 7 EPICLUSIANONE; 9 (TETRAHYDRO 2 FURYL)ADENINE; ALLERGEN; APAMIN; BENZOPHENONE; CARBACHOL; CYCLIC GMP; DRUG VEHICLE; GARCINIA BRASILIENSIS EXTRACT; GLIBENCLAMIDE; GUANYLATE CYCLASE INHIBITOR; HISTAMINE; METHACHOLINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; POTASSIUM CHANNEL BLOCKING AGENT; SEROTONIN; SPASMOLYTIC AGENT; TETRYLAMMONIUM; THEOPHYLLINE; UNCLASSIFIED DRUG;

AIRWAY OBSTRUCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BREATHING MUSCLE; BRONCHUS OBSTRUCTION; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; GARCINIA; GARCINIA BRASILIENSIS; GUINEA PIG; MALE; MEDICINAL PLANT; MOUSE; MUSCLE RELAXATION; NONHUMAN; PRIORITY JOURNAL; TRACHEA;

ANIMALS; BENZOPHENONES; BENZOQUINONES; CALCIUM CHANNELS; CARBACHOL; CRICETINAE; CYCLIC GMP; EPITHELIUM; FEMALE; HISTAMINE; KATP CHANNELS; MALE; METHACHOLINE CHLORIDE; MICE; MICE, INBRED BALB C; MUSCLE RELAXATION; MUSCLE, SMOOTH; NITRIC OXIDE; PARASYMPATHOLYTICS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; SIGNAL TRANSDUCTION; TRACHEA;

EID: 52649084329     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.138032     Document Type: Article

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