Proteomic profiling of endothelin-1-stimulated hypertrophic cardiomyocytes reveals the increase of four different desmin species and α-B-crystallin

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1784, Issue 7-8, 2008, Pages 1068-1076

  Agnetti, Giulio ^a,c   Bezstarosti, Karel ^b   Dekkers, Dick H W ^b   Verhoeven, Adrie J M ^b   Giordano, Emanuele ^a   Guarnieri, Carlo ^a   Caldarera, Claudio M ^a   Van Eyk, Jennifer E ^b   Lamers, Jos M J ^b  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Desmin; Endothelin; Hypertrophy; Mitochondria; Proteomics

Indexed keywords

ALPHA CRYSTALLIN; AMYLOID; BETA CRYSTALLIN; DESMIN; ENDOTHELIN 1; HEAT SHOCK PROTEIN 60;

ANIMAL CELL; ARTICLE; CELL LYSATE; CELLULAR DISTRIBUTION; CYTOSKELETON; HEART MUSCLE CELL; HYPERTROPHIC CARDIOMYOPATHY; INTERMEDIATE FILAMENT; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEOMICS; RAT; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ANIMALS; CARDIOMEGALY; CELLS, CULTURED; CHROMATOGRAPHY, LIQUID; DESMIN; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENDOTHELIN-1; HEAT-SHOCK PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MYOCYTES, CARDIAC; PROTEOMICS; RATS; RATS, WISTAR; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

RATTUS;

EID: 52449135472     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2008.04.003     Document Type: Article

References (49)

1. Lorell B.H., and Carabello B.A. Left ventricular hypertrophy: pathogenesis, detection, and prognosis. Circulation 102 (2000) 470-479
2. Houser S.R., and Lakatta E.G. Function of the cardiac myocyte in the conundrum of end-stage, dilated human heart failure. Circulation 99 (1999) 600-604
3. Hunter J.J., and Chien K.R. Signaling pathways for cardiac hypertrophy and failure. N. Engl. J. Med. 341 (1999) 1276-1283
4. Brancaccio M., Fratta L., Notte A., Hirsch E., Poulet R., Guazzone S., De Acetis M., Vecchione C., Marino G., Altruda F., Silengo L., Tarone G., and Lembo G. Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload. Nat. Med. 9 (2003) 68-75
5. Hoshijima M., and Chien K.R. Mixed signals in heart failure: cancer rules. J. Clin. Invest. 109 (2002) 849-855
6. van Heugten H.A., van Setten M.C., Eizema K., Verdouw P.D., and Lamers J.M. Sarcoplasmic reticulum Ca2+ ATPase promoter activity during endothelin-1 induced hypertrophy of cultured rat cardiomyocytes. Cardiovasc. Res. 37 (1998) 503-514
7. Lamers J.M., Eskildsen-Helmond Y.E., Resink A.M., de Jonge H.W., Bezstarosti K., Sharma H.S., and van Heugten H.A. Endothelin-1-induced phospholipase C-beta and D and protein kinase C isoenzyme signaling leading to hypertrophy in rat cardiomyocytes. J. Cardiovasc. Pharmacol. 26 Suppl 3 (1995) S100-S103
8. Colucci W.S. Myocardial endothelin. Does it play a role in myocardial failure?. Circulation 93 (1996) 1069-1072
9. Bogoyevitch M.A., Glennon P.E., Andersson M.B., Clerk A., Lazou A., Marshall C.J., Parker P.J., and Sugden P.H. Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy. J. Biol. Chem. 269 (1994) 1110-1119
10. Sanbe A., Osinska H., Saffitz J.E., Glabe C.G., Kayed R., Maloyan A., and Robbins J. Desmin-related cardiomyopathy in transgenic mice: a cardiac amyloidosis. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 10132-10136
11. Capetanaki Y. Desmin cytoskeleton: a potential regulator of muscle mitochondrial behavior and function. Trends Cardiovasc. Med. 12 (2002) 339-348
12. Maloyan A., Sanbe A., Osinska H., Westfall M., Robinson D., Imahashi K., Murphy E., and Robbins J. Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desmin-related cardiomyopathy. Circulation 112 (2005) 3451-3461
13. de Jonge H.W., Dekkers D.H., Houtsmuller A.B., Sharma H.S., and Lamers J.M. Differential signaling and hypertrophic responses in cyclically stretched vs endothelin-1 stimulated neonatal rat cardiomyocytes. Cell Biochem. Biophys. 47 (2007) 21-32
14. Faber M.J., Agnetti G., Bezstarosti K., Lankhuizen I.M., Dalinghaus M., Guarnieri C., Caldarera C.M., Helbing W.A., and Lamers J.M. Recent developments in proteomics: implications for the study of cardiac hypertrophy and failure. Cell Biochem. Biophys. 44 (2006) 11-29
15. Van Heugten H.A., Bezstarosti K., Dekkers D.H., and Lamers J.M. Homologous desensitization of the endothelin-1 receptor mediated phosphoinositide response in cultured neonatal rat cardiomyocytes. J.Mol.Cell.Cardiol. 25 (1993) 41-52
16. Sanbe A., Osinska H., Villa C., Gulick J., Klevitsky R., Glabe C.G., Kayed R., and Robbins J. Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 13592-13597
17. Ralston E., Lu Z., Biscocho N., Soumaka E., Mavroidis M., Prats C., Lomo T., Capetanaki Y., and Ploug T. Blood vessels and desmin control the positioning of nuclei in skeletal muscle fibers. J. Cell. Physiol. 209 (2006) 874-882
18. Jager D., Jungblut P.R., and Muller-Werdan U. Separation and identification of human heart proteins. J. Chromatogr. B. Analyt Technol. Biomed. Life. Sci. 771 (2002) 131-153
19. Faber M.J., Dalinghaus M., Lankhuizen I.M., Bezstarosti K., Dekkers D.H., Duncker D.J., Helbing W.A., and Lamers J.M. Proteomic changes in the pressure overloaded right ventricle after 6 weeks in young rats: correlations with the degree of hypertrophy. Proteomics 5 (2005) 2519-2530
20. Franz W.M., Muller O.J., and Katus H.A. Cardiomyopathies: from genetics to the prospect of treatment. Lancet 358 (2001) 1627-1637
21. Capetanaki Y., Bloch R.J., Kouloumenta A., Mavroidis M., and Psarras S. Muscle intermediate filaments and their links to membranes and membranous organelles. Exp. Cell Res. 313 (2007) 2063-2076
22. Francalanci P., Gallo P., Bernucci P., Silver M.D., and d'Amati G. The pattern of desmin filaments in myocardial disarray. Hum. Pathol. 26 (1995) 262-266
23. Schaper J., Froede R., Hein S., Buck A., Hashizume H., Speiser B., Friedl A., and Bleese N. Impairment of the myocardial ultrastructure and changes of the cytoskeleton in dilated cardiomyopathy. Circulation 83 (1991) 504-514
24. Wilke A., Schonian U., Herzum M., Hengstenberg C., Hufnagel G., Brilla C.G., and Maisch B. The extracellular matrix and cytoskeleton of the myocardium in cardiac inflammatory reaction. Herz 20 (1995) 95-108
25. Corbett J.M., Why H.J., Wheeler C.H., Richardson P.J., Archard L.C., Yacoub M.H., and Dunn M.J. Cardiac protein abnormalities in dilated cardiomyopathy detected by two-dimensional polyacrylamide gel electrophoresis. Electrophoresis 19 (1998) 2031-2042
26. Heling A., Zimmermann R., Kostin S., Maeno Y., Hein S., Devaux B., Bauer E., Klovekorn W.P., Schlepper M., Schaper W., and Schaper J. Increased expression of cytoskeletal, linkage, and extracellular proteins in failing human myocardium. Circ. Res. 86 (2000) 846-853
27. Nelson W.J., and Traub P. Proteolysis of vimentin and desmin by the Ca2+-activated proteinase specific for these intermediate filament proteins. Mol. Cell. Biol. 3 (1983) 1146-1156
28. Li D., Tapscoft T., Gonzalez O., Burch P.E., Quinones M.A., Zoghbi W.A., Hill R., Bachinski L.L., Mann D.L., and Roberts R. Desmin mutation responsible for idiopathic dilated cardiomyopathy. Circulation 100 (1999) 461-464
29. Sjoberg G., Saavedra-Matiz C.A., Rosen D.R., Wijsman E.M., Borg K., Horowitz S.H., and Sejersen T. A missense mutation in the desmin rod domain is associated with autosomal dominant distal myopathy, and exerts a dominant negative effect on filament formation. Hum. Mol. Genet. 8 (1999) 2191-2198
30. Weisleder N., Soumaka E., Abbasi S., Taegtmeyer H., and Capetanaki Y. Cardiomyocyte-specific desmin rescue of desmin null cardiomyopathy excludes vascular involvement. J. Mol. Cell. Cardiol. 36 (2004) 121-128
31. Milner D.J., Mavroidis M., Weisleder N., and Capetanaki Y. Desmin cytoskeleton linked to muscle mitochondrial distribution and respiratory function. J. Cell Biol. 150 (2000) 1283-1298
32. Capetanaki Y. Desmin cytoskeleton in healthy and failing heart. Heart Fail. Rev. 5 (2000) 203-220
33. Lesnefsky E.J., Moghaddas S., Tandler B., Kerner J., and Hoppel C.L. Mitochondrial dysfunction in cardiac disease: ischemia-reperfusion, aging, and heart failure. J. Mol. Cell. Cardiol. 33 (2001) 1065-1089
34. Wang X., Osinska H., Dorn II G.W., Nieman M., Lorenz J.N., Gerdes A.M., Witt S., Kimball T., Gulick J., and Robbins J. Mouse model of desmin-related cardiomyopathy. Circulation 103 (2001) 2402-2407
35. Wang X., Klevitsky R., Huang W., Glasford J., Li F., and Robbins J. AlphaB-crystallin modulates protein aggregation of abnormal desmin. Circ. Res. 93 (2003) 998-1005
36. Wang X., Osinska H., Klevitsky R., Gerdes A.M., Nieman M., Lorenz J., Hewett T., and Robbins J. Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in mice. Circ. Res. 89 (2001) 84-91
37. Liu J., Tang M., Mestril R., and Wang X. Aberrant protein aggregation is essential for a mutant desmin to impair the proteolytic function of the ubiquitin-proteasome system in cardiomyocytes. J. Mol. Cell. Cardiol. 40 (2006) 451-454
38. Chen Q., Liu J.B., Horak K.M., Zheng H., Kumarapeli A.R., Li J., Li F., Gerdes A.M., Wawrousek E.F., and Wang X. Intrasarcoplasmic amyloidosis impairs proteolytic function of proteasomes in cardiomyocytes by compromising substrate uptake. Circ. Res. 97 (2005) 1018-1026
39. Patterson C. Search and destroy: the role of protein quality control in maintaining cardiac function. J. Mol. Cell. Cardiol. 40 (2006) 438-441
40. Wang X., and Robbins J. Heart failure and protein quality control. Circ. Res. 99 (2006) 1315-1328
41. Vorum H., Hager H., Christensen B.M., Nielsen S., and Honore B. Human calumenin localizes to the secretory pathway and is secreted to the medium. Exp. Cell Res. 248 (1999) 473-481
42. Coppinger J.A., Cagney G., Toomey S., Kislinger T., Belton O., McRedmond J.P., Cahill D.J., Emili A., Fitzgerald D.J., and Maguire P.B. Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions. Blood 103 (2004) 2096-2104
43. Vorum H., Jacobsen C., and Honore B. Calumenin interacts with serum amyloid P component. FEBS Lett. 465 (2000) 129-134
44. Ostergaard M., Hansen G.A., Vorum H., and Honore B. Proteomic profiling of fibroblasts reveals a modulating effect of extracellular calumenin on the organization of the actin cytoskeleton. Proteomics 6 (2006) 3509-3519
45. Gupta S., and Knowlton A.A. HSP60 trafficking in adult cardiac myocytes: role of the exosomal pathway. Am. J. Physiol, Heart Circ. Physiol. (2007)
46. Gupta S., and Knowlton A.A. HSP60, Bax, apoptosis and the heart. J. Cell. Mol. Med. 9 (2005) 51-58
47. Knowlton A.A., and Gupta S. HSP60, Bax, and cardiac apoptosis. Cardiovasc. Toxicol. 3 (2003) 263-268
48. Chen H.W., Hsu C., Lu T.S., Wang S.J., and Yang R.C. Heat shock pretreatment prevents cardiac mitochondrial dysfunction during sepsis. Shock 20 (2003) 274-279
49. Nelson W.J., and Traub P. Purification and further characterization of the Ca2+-activated proteinase specific for the intermediate filament proteins vimentin and desmin. J. Biol. Chem. 257 (1982) 5544-5553