메뉴 건너뛰기




Volumn 6, Issue 4, 2008, Pages 296-305

Levels of N-linked glycosylation on th V1 loop of HIV-1 Env proteins and their relationship to the antigenicity of Env from primary viral isolates

Author keywords

Antigenicity; Env; HIV 1; N linked glocosylation sites; V1 loop

Indexed keywords

DNA VACCINE; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; NEUTRALIZING ANTIBODY; VIRUS ANTIGEN; VIRUS ENVELOPE PROTEIN; VIRUS GLYCOPROTEIN;

EID: 52449127095     PISSN: 1570162X     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016208785132518     Document Type: Review
Times cited : (5)

References (56)
  • 1
    • 52449114165 scopus 로고    scopus 로고
    • WHO. Cumulative Number of Confirmed Human Cases of Avian Influenza A/ (H5N1) Reported to WHO. 2007 [date accessed June 4, 2007]; Available from: http://www.who.int/csr/disease/avian_influenza/country/ cases_table_2007_05_31/en/index.html
    • WHO. Cumulative Number of Confirmed Human Cases of Avian Influenza A/ (H5N1) Reported to WHO. 2007 [date accessed June 4, 2007]; Available from: http://www.who.int/csr/disease/avian_influenza/country/ cases_table_2007_05_31/en/index.html
  • 2
    • 4043060710 scopus 로고    scopus 로고
    • Correlates of immune protection in HIV-1 infection: What we know, what we don't know, what we should know
    • Pantaleo G, Koup RA. Correlates of immune protection in HIV-1 infection: what we know, what we don't know, what we should know. Nat Med 2004;10(8): 806-10.
    • (2004) Nat Med , vol.10 , Issue.8 , pp. 806-810
    • Pantaleo, G.1    Koup, R.A.2
  • 3
    • 4043124699 scopus 로고    scopus 로고
    • Urgently needed: A filter for the HIV-1 vaccine pipeline
    • Moore JP, Burton DR. Urgently needed: a filter for the HIV-1 vaccine pipeline. Nat Med 2004; 10(8): 769-71.
    • (2004) Nat Med , vol.10 , Issue.8 , pp. 769-771
    • Moore, J.P.1    Burton, D.R.2
  • 4
    • 0035815437 scopus 로고    scopus 로고
    • Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine
    • Amara RR, Villinger F, Altman JD, et al. Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine. Science 2001; 292(5514): 69-74.
    • (2001) Science , vol.292 , Issue.5514 , pp. 69-74
    • Amara, R.R.1    Villinger, F.2    Altman, J.D.3
  • 5
    • 0033766645 scopus 로고    scopus 로고
    • Control of Viremia and Prevention of Clinical AIDS in Rhesus Monkeys by Cytokine-Augumented DNA Vaccination
    • Barouch DH, Santra S, Schmitz JE, et al. Control of Viremia and Prevention of Clinical AIDS in Rhesus Monkeys by Cytokine-Augumented DNA Vaccination. Science 2000; 290: 486-92.
    • (2000) Science , vol.290 , pp. 486-492
    • Barouch, D.H.1    Santra, S.2    Schmitz, J.E.3
  • 6
    • 0037122719 scopus 로고    scopus 로고
    • Replication-incompetent adeno-viral vaccine vector elicits effective anti-immunodeficiency-virus immunity
    • Shiver JW, Fu TM, Chen L, et al. Replication-incompetent adeno-viral vaccine vector elicits effective anti-immunodeficiency-virus immunity. Nature 2002; 415(6869): 331-5.
    • (2002) Nature , vol.415 , Issue.6869 , pp. 331-335
    • Shiver, J.W.1    Fu, T.M.2    Chen, L.3
  • 7
    • 36249005448 scopus 로고    scopus 로고
    • AIDS research. Did Merck's failed HIV vaccine cause harm?
    • Cohen J. AIDS research. Did Merck's failed HIV vaccine cause harm? Science 2007; 318(5853): 1048-9.
    • (2007) Science , vol.318 , Issue.5853 , pp. 1048-1049
    • Cohen, J.1
  • 8
    • 0037456827 scopus 로고    scopus 로고
    • Antibody neutralization and escape by HIV-1
    • Wei X, Decker JM, Wang S, et al. Antibody neutralization and escape by HIV-1. Nature 2003; 422(6929): 307-12.
    • (2003) Nature , vol.422 , Issue.6929 , pp. 307-312
    • Wei, X.1    Decker, J.M.2    Wang, S.3
  • 10
    • 0029102137 scopus 로고
    • Genetic analysis of human immunodeficiency virus type 1 strains from patients in Cyprus: Identification of a new subtype designated subtype I
    • Kostrikis LG, Bagdades E, Cao Y, Zhang L, Dimitriou D, Ho DD. Genetic analysis of human immunodeficiency virus type 1 strains from patients in Cyprus: identification of a new subtype designated subtype I. J Virol 1995; 69(10): 6122-30.
    • (1995) J Virol , vol.69 , Issue.10 , pp. 6122-6130
    • Kostrikis, L.G.1    Bagdades, E.2    Cao, Y.3    Zhang, L.4    Dimitriou, D.5    Ho, D.D.6
  • 11
    • 0029063822 scopus 로고
    • Biological and molecular characterization of subtype D, G, and A/D recombinant HIV-1 transmissions in Sweden
    • Leitner T, Escanilla D, Marquina S, et al. Biological and molecular characterization of subtype D, G, and A/D recombinant HIV-1 transmissions in Sweden. Virology 1995; 209(1): 136-46.
    • (1995) Virology , vol.209 , Issue.1 , pp. 136-146
    • Leitner, T.1    Escanilla, D.2    Marquina, S.3
  • 12
    • 0028917760 scopus 로고
    • Genetic diversity of the envelope glycoprotein from human immunodeficiency virus type 1 isolates of African origin
    • Louwagie J, Janssens W, Mascola J, et al. Genetic diversity of the envelope glycoprotein from human immunodeficiency virus type 1 isolates of African origin. J Virol 1995; 69(l): 263-71.
    • (1995) J Virol , vol.69 , Issue.L , pp. 263-271
    • Louwagie, J.1    Janssens, W.2    Mascola, J.3
  • 13
    • 0023740248 scopus 로고
    • Rates and dates of divergence between AIDS virus nucleotide sequences
    • Li WH, Tanimura M, Sharp PM. Rates and dates of divergence between AIDS virus nucleotide sequences. Mol Biol Evol 1988; 5(4): 313-30.
    • (1988) Mol Biol Evol , vol.5 , Issue.4 , pp. 313-330
    • Li, W.H.1    Tanimura, M.2    Sharp, P.M.3
  • 14
    • 0026707516 scopus 로고
    • HIV-1 intrapatient sequence diversity in the immunogenic V3 region
    • Korber B, Wolinsky S, Haynes B, et al. HIV-1 intrapatient sequence diversity in the immunogenic V3 region. AIDS Res Hum Retroviruses 1992; 8(8): 1461-5.
    • (1992) AIDS Res Hum Retroviruses , vol.8 , Issue.8 , pp. 1461-1465
    • Korber, B.1    Wolinsky, S.2    Haynes, B.3
  • 15
    • 0028038231 scopus 로고
    • Genetic and phylogenetic analysis of env subtypes G and H in central Africa
    • Janssens W, Heyndrickx L, Fransen K, et al. Genetic and phylogenetic analysis of env subtypes G and H in central Africa. AIDS Res Hum Retroviruses 1994; 10(7): 877-9.
    • (1994) AIDS Res Hum Retroviruses , vol.10 , Issue.7 , pp. 877-879
    • Janssens, W.1    Heyndrickx, L.2    Fransen, K.3
  • 16
    • 0027957790 scopus 로고
    • A new subtype of human immunodeficiency virus type 1 (MVP-5180) from Cameroon
    • Gurtler LG, Hauser PH, Eberle J, et al. A new subtype of human immunodeficiency virus type 1 (MVP-5180) from Cameroon. J Virol 1994; 68(3): 1581-5.
    • (1994) J Virol , vol.68 , Issue.3 , pp. 1581-1585
    • Gurtler, L.G.1    Hauser, P.H.2    Eberle, J.3
  • 17
    • 0031695516 scopus 로고    scopus 로고
    • Identification of a new human immunodeficiency virus type 1 distinct from group M and group O
    • Simon F, Mauclere P, Roques P, et al. Identification of a new human immunodeficiency virus type 1 distinct from group M and group O. Nat Med 1998; 4(9): 1032-7.
    • (1998) Nat Med , vol.4 , Issue.9 , pp. 1032-1037
    • Simon, F.1    Mauclere, P.2    Roques, P.3
  • 18
    • 0030018993 scopus 로고    scopus 로고
    • Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID Networks for HIV Isolation and Characterization
    • Gao F, Morrison SG, Robertson DL, et al. Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID Networks for HIV Isolation and Characterization. J Virol 1996; 70(3): 1651-67.
    • (1996) J Virol , vol.70 , Issue.3 , pp. 1651-1667
    • Gao, F.1    Morrison, S.G.2    Robertson, D.L.3
  • 19
    • 0033394084 scopus 로고    scopus 로고
    • Genetic diversity of HIV- group M from Cameroon and Republic of Congo
    • Mboudjeka I, Bikandou B, Zekeng L, et al. Genetic diversity of HIV- group M from Cameroon and Republic of Congo. Arch Virol 1999; 144(12): 2291-311.
    • (1999) Arch Virol , vol.144 , Issue.12 , pp. 2291-2311
    • Mboudjeka, I.1    Bikandou, B.2    Zekeng, L.3
  • 20
    • 0028122996 scopus 로고
    • Genotypic subtypes of HIV-1 in Cameroon
    • Nkengasong JN, Janssens W, Heyndrickx L, et al. Genotypic subtypes of HIV-1 in Cameroon. AIDS 1994; 8(10): 1405-12.
    • (1994) AIDS , vol.8 , Issue.10 , pp. 1405-1412
    • Nkengasong, J.N.1    Janssens, W.2    Heyndrickx, L.3
  • 21
    • 0033755804 scopus 로고    scopus 로고
    • Unprecedented degree of human immunodeficiency virus type 1 (HIV-1) group M genetic diversity in the Democratic Republic of Congo suggests that the HIV-1 pandemic originated in Central Africa
    • Vidal N, Peeters M, Mulanga-Kabeya C, et al. Unprecedented degree of human immunodeficiency virus type 1 (HIV-1) group M genetic diversity in the Democratic Republic of Congo suggests that the HIV-1 pandemic originated in Central Africa. J Virol 2000; 74(22): 10498-507.
    • (2000) J Virol , vol.74 , Issue.22 , pp. 10498-10507
    • Vidal, N.1    Peeters, M.2    Mulanga-Kabeya, C.3
  • 22
    • 0037443948 scopus 로고    scopus 로고
    • Human immunodeficiency virus (HIV) seropositivity among uninfected HIV vaccine recipients
    • Ackers ML, Parekh B, Evans TG, et al. Human immunodeficiency virus (HIV) seropositivity among uninfected HIV vaccine recipients. J Infect Dis 2003; 187(6): 879-86.
    • (2003) J Infect Dis , vol.187 , Issue.6 , pp. 879-886
    • Ackers, M.L.1    Parekh, B.2    Evans, T.G.3
  • 23
  • 24
    • 0031749469 scopus 로고    scopus 로고
    • A role for carbohydrates in immune evasion in AIDS
    • Reitter JN, Means RE, Desrosiers RC. A role for carbohydrates in immune evasion in AIDS. Nat Med 1998; 4(6): 679-84.
    • (1998) Nat Med , vol.4 , Issue.6 , pp. 679-684
    • Reitter, J.N.1    Means, R.E.2    Desrosiers, R.C.3
  • 25
    • 0031748799 scopus 로고    scopus 로고
    • Identification of replication-competent strains of simian immunodeficiency virus lacking multiple attachment sites for N-linked carbohydrates in variable regions 1 and 2 of the surface envelope protein
    • Reitter JN, Desrosiers RC. Identification of replication-competent strains of simian immunodeficiency virus lacking multiple attachment sites for N-linked carbohydrates in variable regions 1 and 2 of the surface envelope protein. J Virol 1998; 72(7): 5399-407.
    • (1998) J Virol , vol.72 , Issue.7 , pp. 5399-5407
    • Reitter, J.N.1    Desrosiers, R.C.2
  • 26
    • 0031906852 scopus 로고    scopus 로고
    • Immunogenicity of DNA vaccines expressing human immunodeficiency virus type 1 envelope glycoprotein with and without deletions in the V1/2 and V3 regions
    • Lu S, Wyatt R, Richmond JF, et al. Immunogenicity of DNA vaccines expressing human immunodeficiency virus type 1 envelope glycoprotein with and without deletions in the V1/2 and V3 regions. AIDS Res Hum Retroviruses 1998; 14(2): 151-5.
    • (1998) AIDS Res Hum Retroviruses , vol.14 , Issue.2 , pp. 151-155
    • Lu, S.1    Wyatt, R.2    Richmond, J.F.3
  • 27
    • 0028107685 scopus 로고
    • Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies
    • Moore JP, Sattentau QJ, Wyatt R, Sodroski J. Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies. J Virol 1994; 68(1): 469-84.
    • (1994) J Virol , vol.68 , Issue.1 , pp. 469-484
    • Moore, J.P.1    Sattentau, Q.J.2    Wyatt, R.3    Sodroski, J.4
  • 28
    • 0034063445 scopus 로고    scopus 로고
    • Variable-Loop-Deleted Variants of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Can Be Stabilized by an Intermolecular Disulfide Bond between the gp120 and gp41 Subunits
    • Sanders RW, Schiffner L, Master A, et al. Variable-Loop-Deleted Variants of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Can Be Stabilized by an Intermolecular Disulfide Bond between the gp120 and gp41 Subunits. J Virol 2000; 74(11): 5091-100.
    • (2000) J Virol , vol.74 , Issue.11 , pp. 5091-5100
    • Sanders, R.W.1    Schiffner, L.2    Master, A.3
  • 29
    • 0029119783 scopus 로고
    • Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp 120 epitopes induced by receptor binding
    • Wyatt R, Moore J, Accola M, Desjardin E, Robinson J, Sodroski J. Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp 120 epitopes induced by receptor binding. J Virol 1995; 69(9): 5723-33.
    • (1995) J Virol , vol.69 , Issue.9 , pp. 5723-5733
    • Wyatt, R.1    Moore, J.2    Accola, M.3    Desjardin, E.4    Robinson, J.5    Sodroski, J.6
  • 30
    • 0027194743 scopus 로고
    • Functional and immunologic characterization of human immunodeficiency virus type 1 envelope glycoproteins containing deletions of the major variable regions
    • Wyatt R, Sullivan N, Thali M, et al. Functional and immunologic characterization of human immunodeficiency virus type 1 envelope glycoproteins containing deletions of the major variable regions. J Virol 1993; 67(8): 4557-65.
    • (1993) J Virol , vol.67 , Issue.8 , pp. 4557-4565
    • Wyatt, R.1    Sullivan, N.2    Thali, M.3
  • 31
    • 0035500872 scopus 로고    scopus 로고
    • DNA-immunization with a V2 deleted HIV-1 envelope elicits protective antibodies in macaques
    • Cherpelis S, Jin X, Gettie A, et al. DNA-immunization with a V2 deleted HIV-1 envelope elicits protective antibodies in macaques. Immunol Lett 2001; 79(1-2): 47-55.
    • (2001) Immunol Lett , vol.79 , Issue.1-2 , pp. 47-55
    • Cherpelis, S.1    Jin, X.2    Gettie, A.3
  • 32
    • 0035148591 scopus 로고    scopus 로고
    • DNA vaccination with the human immunodeficiency virus type 1 SF162DeltaV2 envelope elicits immune responses that offer partial protection from simian/human immunodeficiency virus infection to CD8(+) T-cell-depleted rhesus macaques
    • Cherpelis S, Shrivastava I, Gettie A, et al. DNA vaccination with the human immunodeficiency virus type 1 SF162DeltaV2 envelope elicits immune responses that offer partial protection from simian/human immunodeficiency virus infection to CD8(+) T-cell-depleted rhesus macaques. J Virol 2001; 75(3): 1547-50.
    • (2001) J Virol , vol.75 , Issue.3 , pp. 1547-1550
    • Cherpelis, S.1    Shrivastava, I.2    Gettie, A.3
  • 33
    • 0035000679 scopus 로고    scopus 로고
    • The ability of an oligomeric human immunodeficiency virus type 1 (HIV-1) envelope antigen to elicit neutralizing antibodies against primary HIV-1 isolates is improved following partial deletion of the second hypervariable region
    • Barnett SW, Lu S, Srivastava I, et al. The ability of an oligomeric human immunodeficiency virus type 1 (HIV-1) envelope antigen to elicit neutralizing antibodies against primary HIV-1 isolates is improved following partial deletion of the second hypervariable region. J Virol 2001; 75(12): 5526-40.
    • (2001) J Virol , vol.75 , Issue.12 , pp. 5526-5540
    • Barnett, S.W.1    Lu, S.2    Srivastava, I.3
  • 34
    • 0031472867 scopus 로고    scopus 로고
    • Developing DNA vaccines against immunodeficiency viruses
    • Lu S. Developing DNA vaccines against immunodeficiency viruses. Curr Top Microbiol Immunol 1998; 226: 161-73.
    • (1998) Curr Top Microbiol Immunol , vol.226 , pp. 161-173
    • Lu, S.1
  • 36
    • 0027236954 scopus 로고
    • Production of high-titer helper-free retroviruses by transient transfection
    • Pear WS, Nolan GP, Scott ML, Baltimore D. Production of high-titer helper-free retroviruses by transient transfection. Proc Natl Acad Sci USA 1993; 90(18): 8392-6.
    • (1993) Proc Natl Acad Sci USA , vol.90 , Issue.18 , pp. 8392-8396
    • Pear, W.S.1    Nolan, G.P.2    Scott, M.L.3    Baltimore, D.4
  • 37
    • 41549160497 scopus 로고    scopus 로고
    • Delivery of DNA to Skin by Particle Bombardment
    • Heiser WC, ed, Humana Press
    • Wang S, Joshi S, Lu S. Delivery of DNA to Skin by Particle Bombardment. In: Heiser WC, ed. Gene Delivery to Mammalian Cells: Humana Press 2004.
    • (2004) Gene Delivery to Mammalian Cells
    • Wang, S.1    Joshi, S.2    Lu, S.3
  • 39
    • 33746651142 scopus 로고    scopus 로고
    • Polyvalent HIV-1 Env vaccine formulations delivered by the DNA priming plus protein boosting approach are effective in generating neutralizing antibodies against primary human immunodeficiency virus type 1 isolates from sub-types A, B, C, D and E
    • Wang S, Pal R, Mascola JR, et al. Polyvalent HIV-1 Env vaccine formulations delivered by the DNA priming plus protein boosting approach are effective in generating neutralizing antibodies against primary human immunodeficiency virus type 1 isolates from sub-types A, B, C, D and E. Virology 2006; 350(1): 34-47.
    • (2006) Virology , vol.350 , Issue.1 , pp. 34-47
    • Wang, S.1    Pal, R.2    Mascola, J.R.3
  • 40
    • 0028073184 scopus 로고
    • Exploration of antigenic variation in gp120 from clades A through F of human immunodeficiency virus type 1 by using monoclonal antibodies
    • Moore JP, McCutchan FE, Poon SW, et al. Exploration of antigenic variation in gp120 from clades A through F of human immunodeficiency virus type 1 by using monoclonal antibodies. J Virol 1994; 68(12): 8350-64.
    • (1994) J Virol , vol.68 , Issue.12 , pp. 8350-8364
    • Moore, J.P.1    McCutchan, F.E.2    Poon, S.W.3
  • 41
    • 0032030608 scopus 로고    scopus 로고
    • Serotyping of HIV type 1 infections: Definition, relationship to viral genetic sub-types, and assay evaluation. UNAIDS Network for HIV-1 Isolation and Characterization
    • Cheingsong-Popov R, Osmanov S, Pau CP, et al. Serotyping of HIV type 1 infections: definition, relationship to viral genetic sub-types, and assay evaluation. UNAIDS Network for HIV-1 Isolation and Characterization. AIDS Res Hum Retroviruses 1998; 14(4): 311-8.
    • (1998) AIDS Res Hum Retroviruses , vol.14 , Issue.4 , pp. 311-318
    • Cheingsong-Popov, R.1    Osmanov, S.2    Pau, C.P.3
  • 42
    • 18744394633 scopus 로고    scopus 로고
    • The C108g epitope in the V2 domain of gp120 functions as a potent neutralization target when introduced into envelope proteins derived from human immunodeficiency virus type 1 primary isolates
    • Pinter A, Honnen WJ, D'Agostino P, Gorny MK, Zolla-Pazner S, Kayman SC. The C108g epitope in the V2 domain of gp120 functions as a potent neutralization target when introduced into envelope proteins derived from human immunodeficiency virus type 1 primary isolates. J Virol 2005; 79(11): 6909-17.
    • (2005) J Virol , vol.79 , Issue.11 , pp. 6909-6917
    • Pinter, A.1    Honnen, W.J.2    D'Agostino, P.3    Gorny, M.K.4    Zolla-Pazner, S.5    Kayman, S.C.6
  • 43
    • 0027154014 scopus 로고
    • A single amino acid substitution in the V1 loop of human immunodeficiency virus type 1 gp120 alters cellular tropism
    • Boyd MT, Simpson GR, Cann AJ, Johnson MA, Weiss RA. A single amino acid substitution in the V1 loop of human immunodeficiency virus type 1 gp120 alters cellular tropism. J Virol 1993; 67(6): 3649-52.
    • (1993) J Virol , vol.67 , Issue.6 , pp. 3649-3652
    • Boyd, M.T.1    Simpson, G.R.2    Cann, A.J.3    Johnson, M.A.4    Weiss, R.A.5
  • 44
    • 0030025979 scopus 로고    scopus 로고
    • Cooperative effects of the human immunodeficiency virus type 1 envelope variable loops V1 and V3 in mediating infectivity for T cells
    • Carrillo A, Ratner L. Cooperative effects of the human immunodeficiency virus type 1 envelope variable loops V1 and V3 in mediating infectivity for T cells. J Virol 1996; 70(2): 1310-6.
    • (1996) J Virol , vol.70 , Issue.2 , pp. 1310-1316
    • Carrillo, A.1    Ratner, L.2
  • 45
    • 0028322510 scopus 로고
    • Identification of an N-linked glycan in the V1-loop of HIV-1 gp120 influencing neutralization by anti-V3 antibodies and soluble CD4
    • Gram GJ, Hemming A, Bolmstedt A, et al. Identification of an N-linked glycan in the V1-loop of HIV-1 gp120 influencing neutralization by anti-V3 antibodies and soluble CD4. Arch Virol 1994; 139(3-4): 253-61.
    • (1994) Arch Virol , vol.139 , Issue.3-4 , pp. 253-261
    • Gram, G.J.1    Hemming, A.2    Bolmstedt, A.3
  • 46
    • 52449093798 scopus 로고    scopus 로고
    • Los Alamos National Laboratory. HIV Molecular Immunology Compendium, accessed March 25, 2008] Available from
    • Part IV. HIV Monoclonal Antibodies. Los Alamos National Laboratory. HIV Molecular Immunology Compendium 2001 [accessed March 25, 2008] Available from: http://www.hiv.lanl.gov/content/immunology/contents2000.html.
    • (2001) Monoclonal Antibodies
  • 47
    • 0030812563 scopus 로고    scopus 로고
    • Replication and neutralization of human immunodeficiency virus type 1 lacking the V1 and V2 variable loops of the gp120 envelope glycoprotein
    • Cao J, Sullivan N, Desjardin E, et al. Replication and neutralization of human immunodeficiency virus type 1 lacking the V1 and V2 variable loops of the gp120 envelope glycoprotein. J Virol 1997; 71(12): 9808-12.
    • (1997) J Virol , vol.71 , Issue.12 , pp. 9808-9812
    • Cao, J.1    Sullivan, N.2    Desjardin, E.3
  • 48
    • 0030842609 scopus 로고    scopus 로고
    • Specific N-linked and O-linked glycosylation modifications in the envelope V1 domain of simian immunodeficiency virus variants that evolve in the host alter recognition by neutralizing antibodies
    • Chackerian B, Rudensey LM, Overbaugh J. Specific N-linked and O-linked glycosylation modifications in the envelope V1 domain of simian immunodeficiency virus variants that evolve in the host alter recognition by neutralizing antibodies. J Virol 1997; 71(10): 7719-27.
    • (1997) J Virol , vol.71 , Issue.10 , pp. 7719-7727
    • Chackerian, B.1    Rudensey, L.M.2    Overbaugh, J.3
  • 49
    • 0033044138 scopus 로고    scopus 로고
    • Protection of macaques against intrarectal infection by a combination immunization regimen with recombinant simian immunodeficiency virus SIVmne gp160 vaccines
    • Polacino P, Stallard V, Montefiori DC, et al. Protection of macaques against intrarectal infection by a combination immunization regimen with recombinant simian immunodeficiency virus SIVmne gp160 vaccines. J Virol 1999; 73(4): 3134-46.
    • (1999) J Virol , vol.73 , Issue.4 , pp. 3134-3146
    • Polacino, P.1    Stallard, V.2    Montefiori, D.C.3
  • 50
    • 17344361901 scopus 로고    scopus 로고
    • Limited breadth of the protective immunity elicited by simian immunodeficiency virus SIVmne gp160 vaccines in a combination immunization regimen
    • Polacino P, Stallard V, Klaniecki JE, et al. Limited breadth of the protective immunity elicited by simian immunodeficiency virus SIVmne gp160 vaccines in a combination immunization regimen. J Virol 1999; 73(1): 618-30.
    • (1999) J Virol , vol.73 , Issue.1 , pp. 618-630
    • Polacino, P.1    Stallard, V.2    Klaniecki, J.E.3
  • 51
    • 0037393393 scopus 로고    scopus 로고
    • HIV-1: Nature's master of disguise
    • Mascola JR, Montefiori DC. HIV-1: nature's master of disguise. Nat Med 2003; 9(4): 393-4.
    • (2003) Nat Med , vol.9 , Issue.4 , pp. 393-394
    • Mascola, J.R.1    Montefiori, D.C.2
  • 52
    • 0035991710 scopus 로고    scopus 로고
    • Neutralizing antibody responses to HIV-1 infection
    • Morris L. Neutralizing antibody responses to HIV-1 infection. IUBMB Life 2002; 53(4-5): 197-9.
    • (2002) IUBMB Life , vol.53 , Issue.4-5 , pp. 197-199
    • Morris, L.1
  • 53
    • 19944393561 scopus 로고    scopus 로고
    • Enhanced inummogenicity of gp120 protein when combined with recombinant DNA priming to generate antibodies that neutralize the JR-FL primary isolate of human immunodeficiency virus type 1
    • Wang S, Arthos J, Lawrence JM, et al. Enhanced inummogenicity of gp120 protein when combined with recombinant DNA priming to generate antibodies that neutralize the JR-FL primary isolate of human immunodeficiency virus type 1. J Virol 2005; 79(12): 7933-7.
    • (2005) J Virol , vol.79 , Issue.12 , pp. 7933-7937
    • Wang, S.1    Arthos, J.2    Lawrence, J.M.3
  • 54
    • 21644445378 scopus 로고    scopus 로고
    • Evaluating the immunogenicity of a disulfide- stabilized, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1
    • Beddows S, Schulke N, Kirschner M, et al. Evaluating the immunogenicity of a disulfide- stabilized, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1. J Virol 2005; 79(14): 8812-27.
    • (2005) J Virol , vol.79 , Issue.14 , pp. 8812-8827
    • Beddows, S.1    Schulke, N.2    Kirschner, M.3
  • 55
    • 34247166722 scopus 로고    scopus 로고
    • Antigenic and Immunogenic Study of Membrane-Proximal External Region-Grafted gp120 Antigens by a DNA Prime-Protein Boost Immunization Strategy
    • Law M, Cardoso RM, Wilson IA, Burton DR. Antigenic and Immunogenic Study of Membrane-Proximal External Region-Grafted gp120 Antigens by a DNA Prime-Protein Boost Immunization Strategy. J Virol 2007; 81(8): 4272-85.
    • (2007) J Virol , vol.81 , Issue.8 , pp. 4272-4285
    • Law, M.1    Cardoso, R.M.2    Wilson, I.A.3    Burton, D.R.4
  • 56
    • 39149109930 scopus 로고    scopus 로고
    • Balanced cellular and antibody responses induced by the polyvalent DNA prime-protein boost HIV-1 vaccine formulation DP6-001 in healthy human volunteers
    • Wang S, Kennedy J, West K, et al. Balanced cellular and antibody responses induced by the polyvalent DNA prime-protein boost HIV-1 vaccine formulation DP6-001 in healthy human volunteers. Vaccine 2008; 26: 1098-110.
    • (2008) Vaccine , vol.26 , pp. 1098-1110
    • Wang, S.1    Kennedy, J.2    West, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.