Traditional phytochemistry: Identification of drug by 'taste'

Evidence-based Complementary and Alternative Medicine

Volumn 4, Issue 2, 2007, Pages 145-148

  Joshi, Kalpana ^a   Hankey, Alex ^b   Patwardhan, Bhushan ^a  

^a UNIVERSITY OF PUNE   (India)

^b Hethe House   (United Kingdom)

Author keywords

Ayurveda; Drug discovery; Ibruprofen; Oleocanthal; Taste

Indexed keywords

IBUPROFEN; OLEOCANTHAL; OLIVE OIL; UNCLASSIFIED DRUG;

AYURVEDA; CONFORMATION; DRUG IDENTIFICATION; ENZYME ACTIVE SITE; ENZYME BINDING; NOTE; PHYTOCHEMISTRY; PRIORITY JOURNAL; STEREOCHEMISTRY; TASTE;

EID: 52449123689     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1093/ecam/nel064     Document Type: Note

References (29)

1. Beauchamp GK, Keast RS, Morel D, Lin J, Pika J, Han Q, et al. Breslin phytochemistry: ibuprofen-like activity in extra-virgin olive oil. Nature 2005;437:45-6.
2. Valiathan MS. The Legacy of Caraka. Hyderabad, India: Orient Longman, 2004.
3. Sharma H, Clark C. Contemporary Ayurveda. Philadelphia: Churchill Livingstone, 1998.
4. Bodeker G. Evaluating Ayurveda. J Altern Complement Med 2001;7:389-92.
5. Chopra A, Doiphode V. Ayurvedic medicine: core concept, therapeutic principles, and current relevance. Med Clin North Am 2002;86:75-89.
6. Hankey A. The scientific value of Ayurveda. J Altern Complement Med 2005;11:221-5.
7. Patwardhan B, Joshi K, Chopra A. Classification of human population based on Ayurvedic concept of Prakriti. J Altern Complement Med 2005;11:349-53.
8. Patwardhan B, Gautam M. Botanical immunodrugs: scope and opportunities. Drug Discov Today 2005;10:495-502.
9. Heinrich M. Ethnobotany and natural products: the search for new molecules, new treatments of old diseases or a better understanding of indigenous cultures? Curr Top Med Chem 2003;3:141-54.
10. Shepard G. A sensory ecology of medicinal plant therapy in two Amazonian societies. Am Anthropol 2004;106:252-66.
11. Fischer R. Psychology of taste. In: Ohloff G, Thomas AE (eds). Gustation and Olfaction, New York: Academic Press, 1971, 187-237.
12. Lawless HT. Olfactory psychophysics. In: Beauchamp GK, Bartoshuk L (eds). Tasting and Smelling. Chapter 4, San Diego: Academic Press, 1997, 125-74.
13. Brand JG. Biophysics of taste. In: Beauchamp GK, Bartoshuk L (eds). Tasting and Smelling, Chapter 1, San Diego: Academic Press, 1997, 1-24.
14. Halpern BP. Psychophysics of taste. In: Beauchamp GK, Bartoshuk L (eds). Tasting and Smelling. Chapter 3, San Diego: Academic Press, 1997, 77-123.
15. Buck L, Axel A. A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell 1991;65:175-87.
16. Also: Comment, Cell 2004;116(2 Suppl):S117-9.
17. Chess A, Buck L, Dowling MM, Axel R, Ngai J. Molecular biology of smell: expression of the multigene family encoding putative odorant receptors. Cold Spring Harb Symp Quant Biol 1992;57:505-16.
18. Ngai J, Dowling MM, Buck L, Axel R, Chess A. The family of genes encoding odorant receptors in the channel catfish. Cell 1993;72:657-66.
19. Dulac C, Axel R. A novel family of genes encoding putative pheromone receptors in mammals. Cell 1995;83:195-206.
20. Laska M, Genzel D, Wieser A. The number of functional olfactory receptor genes and the relative size of olfactory brain structures are poor predictors of olfactory discrimination performance with enantiomers. Chem Senses 2005;30:171-5.
21. Rodacy PJ, Bender SFA, Bromenshenk JJ, Henderson CB, Bender G. The Training and Deployment of Honeybees to Detect Explosives and Other Agents of Harm. Proceedings of SPIE (The International Society for Optical Engineering), AeroSense CBS Work, April 2002, Vol. 4742-54.
22. Connelly JM, Curby WA, Fox FT, Hallowell SF. Detection of hidden explosives. In: Beveridge A (ed). Forensic Investigation of Explosions. London, UK: Taylor and Francis, 1998, 45-71.
23. Otto J, Brown MF, Long W. Training rats to search and alert on contraband odors. Appl Anim Behav Sci 2002;77:217-32.
24. Willis CM, Church SM, Guest CM, Cook WA, McCarthy N, Branbury AJ, et al. Olfactory detection of human bladder cancer by dogs: proof of principle study. Br Med J 2004;329:712.
25. Ewing G, Ewing E, Hankey A. Virtual Scanning: a new method of health assessment and treatment. Part I: assessment. J Altern Complement Med 2006 (in press).
26. Grakov I. Description of Virtual Scanning system for operators. Sochi, Russia: Mimex 2002. English translation available at: http://www. psychoenergetic.com/strannik/indexuk.html/.
27. Patwardhan B, Vaidya ADB, Chorghade M. Ayurveda and natural product drug discovery. Curr Sci 2004;86:789-99.
28. Cooper EL. Complementary and alternative medicine, when rigorous, can be science. Evid Based Complement Alternat Med 2004;1:1-5.
29. Hankey A. CAM modalities can stimulate advances in theoretical biology. Evid Based Complement Alternat Med 2005;2:5-12.