Successful desensitization with human insulin in a patient with an insulin allergy and hypersensitivity to protamine: A case report

Journal of Medical Case Reports

Volumn 2, Issue , 2008, Pages

  Pföhler, Claudia ^a   Müller, Cornelia S L ^a   Hasselmann, Dirk O ^a   Tilgen, Wolfgang ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTRAPID PENFILL; ANTIHISTAMINIC AGENT; BERLINSULIN H NORMAL; FEXOFENADINE; GLUCOSE; HISTAMINE; HUMAN INSULIN; HUMINSULIN BASAL; IMMUNOGLOBULIN G ANTIBODY; INSULIN; INSULIN ASPART; INSULIN DETEMIR; INSULIN GLARGINE; INSULIN GLULISINE; INSULIN LISPRO; INSULIN NOVO SEMILENTE; INSULIN ZINC SUSPENSION; INSUMAN RAPID; NEUTRAL INSULIN; ORAL ANTIDIABETIC AGENT; PROTAMINE; RECOMBINANT HUMAN INSULIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

AGED; ALLERGY TEST; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ARTICLE; CALORIC RESTRICTION; CASE REPORT; CLINICAL PROTOCOL; DESENSITIZATION; DIABETES CONTROL; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG HYPERSENSITIVITY; DRUG SUBSTITUTION; DRUG TOLERABILITY; DRUG WITHDRAWAL; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN TISSUE; INJECTION SITE PRURITUS; INSULIN ALLERGY; INTRACUTANEOUS TEST; LABORATORY TEST; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL;

EID: 52449109662     PISSN: 17521947     EISSN: 17521947     Source Type: Journal    
DOI: 10.1186/1752-1947-2-283     Document Type: Article

References (19)

1. Liebermann P Allergic reactions to insulin J Am Med Assoc 1971, 215:1106-1112. 10.1001/jama.215.7.1106
2. Darmon P Type III allergy to insulin detemir Diabetes Care 2005, 28(12):2980. 10.2337/diacare.28.12.2980 16306568
3. Kollner A Delayed hypersensitivity to protamine and immediate hypersensitivity to insulin Dtsch Med Wochenschr 1991, 116(33):1234-1238. 1831420
4. Porsche R Brenner ZR Allergy to protamine sulfate Heart Lung 1999, 28(6):418-428. 10.1016/S0147-9563(99)70031-2 10580216
5. Raap U Delayed-type hypersensitivity to protamine as a complication of insulin therapy Contact Dermatitis 2005, 53(1):57-58. 10.1111/ j.0105-1873.2005.00456d.x 15982236
6. Hulshof MM Granulomatous hypersensitivity to protamine as a complication of insulin therapy Br J Dermatol 1992, 127(3):286-288. 10.1111/ j.1365-2133.1992.tb00130.x 1390174
7. Rajpar SF Severe adverse cutaneous reaction to insulin due to cresol sensitivity Contact Dermatitis 2006, 55(2):119-120. 10.1111/ j.0105-1873.2006.0866g.x 16930241
8. Castera V Systemic allergy to human insulin and its rapid and long acting analogs: Successful treatment by continuous subcutaneous insulin lispro infusion Diabetes Metab 2005, 31(4 Pt 1):391-400. 10.1016/ S1262-3636(07)70210-0 16369203
9. Moyes V Insulin allergy in a patient with Type 2 diabetes successfully treated with continuous subcutaneous insulin infusion Diabetes Med 2006, 23(2):204-206. 10.1111/j.1464-5491.2006.01811.x
10. Sola-Gazagnes A Successful treatment of insulin allergy in a type 1 diabetic patient by means of constant subcutaneous pump infusion of insulin Diabetes Care 2003, 26(10):2961-2962. 10.2337/diacare.26.10.2961 14514615
11. Kara C Successful treatment of insulin allergy in a 1-year-old infant with neonatal diabetes by lispro and glargine insulin Diabetes Care 2005, 28(4):983-984. 10.2337/diacare.28.4.983 15793215
12. Matheu V Insulin allergy and resistance successfully treated by desensitisation with aspart insulin Clin Mol Allergy 2005, 3:16. 1352375 16375762 10.1186/1476-7961-3-16
13. Leonet J Solitary pancreas transplantation for life-threatening allergy to human insulin Transpl Int 2006, 19(6):474-477. 10.1111/ j.1432-2277.2006.00282.x 16771868
14. Malaise J Pancreas transplantation for treatment of generalized allergy to human insulin in type 1 diabetes Transpl Proc 2005, 37(6):2839. 10.1016/j.transproceed.2005.05.020
15. Grammer L Chen P Patterson R Evaluation and management of insulin allergy J Allergy Clin Immunol 1983, 71(2):250-254. 10.1016/ 0091-6749(83)90107-0 6337201
16. Airaghi L Lorini M Tedeschi A The insulin analog aspart: A safe alternative in insulin allergy Diabetes Care 2001, 24(11):2000. 10.2337/ diacare.24.11.2000 11679473
17. Asai M Yoshida M Miura Y Immunologic tolerance to intravenously injected insulin N Engl J Med 2006, 354(3):307-309. 10.1056/NEJMc052463 16421379
18. Wessbecher R Management of insulin allergy Allergy 2001, 56(9):919-920. 10.1034/j.1398-9995.2001.00225.x 11551264
19. Barranco R Systemic allergic reaction by a human insulin analog Allergy 2003, 58(6):536-537. 10.1034/j.1398-9995.2003.00143.x 12757463