Allergy to protamine sulfate

Heart and Lung: Journal of Acute and Critical Care

Volumn 28, Issue 6, 1999, Pages 418-428

  Porsche, Renate ^b   Brenner, Zara R ^a  

^a Genesee Hospital   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; AMINOPHYLLINE; GLUCAGON; HEPARIN; HISTAMINE; ISOPHANE INSULIN; LIDOCAINE; METHYLPREDNISOLONE; PROTAMINE; SALBUTAMOL;

ANAPHYLAXIS; ARTICLE; BRONCHOSPASM; CARDIOPULMONARY BYPASS; DRUG HYPERSENSITIVITY; DRUG SAFETY; HEART ARRHYTHMIA; HEMOSTASIS; HEPARINIZATION; HUMAN; HYPOTENSION; INTRAVENOUS DRUG ADMINISTRATION; PRIORITY JOURNAL; RISK BENEFIT ANALYSIS; RISK FACTOR; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0004845095     PISSN: 01479563     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0147-9563(99)70031-2     Document Type: Article

References (34)

1. 1. Weiler JM, Freiman P, Murali DS, et al. Serious adverse reactions to protamine sulfate: Are alternatives needed? J Allergy Clin Immunol 1985;75:297-303.
2. 2 Schapira M, Christman BW. Neutralization of heparin by protamine: Time for a change? Circulation 1990;82:1877-9.
3. 3. Marquardt DL, Wasserman SI. Anaphylaxis. In: Middleton E, et al, editors. Allergy principles and practice. 4th ed. St. Louis: Mosby; 1993. p. 1525-34.
4. 4. Muelleman RL, Lindzon RD, Silver WS. Allergy, hypersensitivity, and anaphylaxis. In: Rosen R, Barkin R, editors. Emergency medicine. 4th ed. New York: Mosby; 1998. p. 2770-2.
5. 5. Clancy J. Basic concepts in immunology. New York: McGraw-Hill; 1998.
6. 6 Tribett D. Mechanism for immunological injury. In: Kinney MR, Packa DR, Dunbar SB, editors. AACN's clinical reference of critical-care nursing, 3rd ed. St. Louis: Mosby; 1993. p. 1038-43.
7. 7 Adelman DC, Kesarwala HH, Fischer TJ. Introduction to the immune system. In: Lawlor GJ, Fischer TJ, Adelman DC, editors. Manual of allergy and immunology. 3rd ed. Boston: Little, Brown; 1995. p. 14-7.
8. 8. Weiss ME, Adkinson NF. Allergy to protamine. Clin Rev Allergy 1991;9:339-55.
9. 9. Weiss ME, Nyhan D, Peng Z, et al. Association of protamine IgE and IgG antibodies with life-threatening reactions to intravenous protamine. N Engl J Med 1989, 1320:886-92.
10. 10. Cormack JG, Levy JH. Adverse reactions to protamine. Coron Artery Dis 1993;4:420-5.
11. 11. Fleisher TA, Gracy DE. Diagnostic immunology. In: Lawlor GJ, Fischer TJ, Adelman DC, editors. Manual of allergy and immunology. 3rd ed Boston: Little, Brown; 1995. p. 446-59.
12. 12. Levy JH, Schweiger IM, Zaidan JR, et al Evaluation of patients at risk for protamine reactions. J Thorac Cardiovasc Surg 1989;98:200-4.
13. 13. Horrow JC, Pharo GH, Levit LS, Freeland C. Neither skin tests nor serum enzyme-linked immunosorbent assay tests provide specificity for protamine allergy. Anesth Analg 1996:82:386-9.
14. 14. Stewart WJ, McSweeney SM, Kelett MA, et al. Increased risk of severe protamine reactions in NPH insulin-dependent diabetics undergoing cardiac catheterization. Circulation 1984;70:788-92.
15. 15 Morel DR, Zapol AM, Thomas SJ, et al. C5a and thromboxane generation associated with pulmonary vaso-and broncho-constriction during protamine reversal of heparin. Anesthesiology 1987;66:597-604.
16. 16 Gottschlich GM, Gravlee GP, Georgitits JW. Adverse reactions to protamine sulfate during cardiac surgery in diabetic and non-diabetic patients. Ann Allergy 1988;61:277-81.
17. 17. Gupta SK, Veith FL, Ascer E, et al. Anaphylaxis reactions to protamine: an often lethal complication in insulin-dependent diabetic patients undergoing vascular surgery. J Vasc Surg 1989;9:342-8.
18. 18. Weiler JM, Gelhaus MA, Carter JG, et al. A prospective study of the risk of an immediate adverse reaction to protamine sulfate during cardiopulmonary bypass surgery. J Allergy Clin Immunol 1990;85:713-9.
19. 19. Roelofse JA, Van Der Bijl P. An anaphylactic reaction to protamine sulfate. Anesth Prog 1991;38:99-100.
20. 20. Takenoshita M, Sugiyama M, Okuno Y, et al. Anaphylactoid reaction to protamine confirmed by plasma tryptase in a diabetic patient during open heart surgery. Anesthesiology 1996; 84:233-5.
21. 21. Neidart PP, Meier B, Polla BS, et al. Fatal anaphylactoid response to protamine after percutaneous transluminal angioplasty. Eur Heart J 1992;13:856-8.
22. 22. Pharo GH, Horrow J, Van Riper DF, Levy JH. Suspected protamine allergy: diagnosis and management for coronary artery surgery. Anesth Analg 1994;78:181-4.
23. 23. Horrow JC. Protamine: a review of its toxicity. Anesth Analg 1985;64:348-61.
24. 24. Levy JH, Zaidan JR, Faraj B. Prospective evaluation of risk of protamine reactions in patients with NPH insulin-dependent diabetes. Anesth Analg 1986;65:739-42.
25. 25. Adourian U, Shampaine EL, Hirshman CA, et al. High-titer protamine-specific IgG antibody associated with anaphylaxis: report of a case and quantitative analysis of antibody in vasectomized men. Anesthesiology 1993;78:368-72.
26. 26. Lawlor GJ, Rosenblatt HM. Anaphylaxis. In: Lawlor GJ, Fischer TJ, Adelman DC, editors. Manual of allergy and immunology. 3rd ed. Boston: Little, Brown; 1995. p. 244-50.
27. 27. McEvoy GK, editor. American hospital formulary service. Bethesda: American Society of Health-System Pharmacists; 1998.
28. 28. Sticco SL. Protamine reaction. CRNA 1993;4:144-7
29. 29. Langer R, Linhardt RJ, Hoffberg S, et al. An enzymatic system for removing heparin in extracorporeal therapy. Science 1982;217:261.
30. 30. Lowenstein E, Lynch K, Robinson DR, et al. Incidence, severity and causation of adverse cardiopulmonary response to protamine reversal of heparin anticoagulation in man. Am Rev Respir Dis 1988;137(Suppl):245.
31. 31. Levy JH. Anaphylactic/anaphylactoid reactions during cardiac surgery. J Clin Anesth 1989;1:426-30.
32. 32. Vincent GM, Janowski M, Menlove R. Protamine allergy reactions during cardiac catheterization and cardiac surgery: risk in patients taking protamine-insulin preparations. Cathet Cardiovasc Diagn 1991;23:164-8.
33. 33. Hughes C, Haddock M. Protamine reaction in a patient undergoing coronary artery bypass grafting. CRNA 1995;6:175-6.
34. 34. Backman SB, Gilron I, Robbins R. Protamine-induced hypotension and bradycardia in a cardiac transplant patient. Can J Anesth 1997;44:520-4.