From enzyme to zymogen: Engineering Vip2, an ADP-ribosyltransferase from Bacillus cereus, for conditional toxicity

Protein Engineering, Design and Selection

Volumn 21, Issue 10, 2008, Pages 631-638

  Jucovic, Milan ^a   Walters, Frederick S ^a   Warren, Gregory W ^a   Palekar, Narendra V ^a   Chen, Jeng S ^a  

^a SYNGENTA BIOTECHNOLOGY INC   (United States)

Author keywords

ADP ribosyltransferase; Conditional toxicity; Proenzyme; Vip2; Zymogen

Indexed keywords

BACTERIOLOGY; BIOCHEMICAL ENGINEERING; BIOLOGICAL SYSTEMS; CHEMICAL REACTIONS; FOOD ADDITIVES; GENETIC ENGINEERING; MONOMERS; POLYMERS; TECHNOLOGY; TOXIC MATERIALS; WEIGHT CONTROL; YEAST;

A-PLANT; ACTIN POLYMERIZATION; ADENOSINE DIPHOSPHATE; ADP-RIBOSYLTRANSFERASE; BACILLUS CEREUS; BIOTECHNOLOGICAL APPLICATIONS; CONDITIONAL TOXICITY; ENZYMATIC ACTIVITIES; INSECT LARVAE; INSECTICIDAL ACTIVITY; INSECTICIDAL PROTEINS; POISONING EFFECTS; PROENZYME; PROPEPTIDE; PROTEIN ENGINEERING; TOXIC PROTEINS; VIP2; WILD-TYPE; ZYMOGEN;

ENZYMES;

ENZYME PRECURSOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN; UNCLASSIFIED DRUG; VEGETATIVE INSECTICIDAL PROTEIN 2;

ARTICLE; BACILLUS CEREUS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ENGINEERING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; WILD TYPE; YEAST;

ADP RIBOSE TRANSFERASES; AMINO ACID SEQUENCE; ANIMALS; BACILLUS CEREUS; BACTERIAL PROTEINS; BACTERIAL TOXINS; BEETLES; ENZYME ACTIVATION; ENZYME PRECURSORS; INSECTICIDES; LARVA; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PEPTIDE LIBRARY; PLANTS; PROTEIN CONFORMATION; PROTEIN ENGINEERING; YEASTS;

BACILLUS CEREUS; DIABROTICA VIRGIFERA VIRGIFERA; HEXAPODA;

EID: 52449099191     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzn038     Document Type: Article

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