Dose-response effect of ferulic acid against nicotine-induced tissue damage and altered lipid levels in experimental rats: A pathohistological evaluation

Fundamental and Clinical Pharmacology

Volumn 22, Issue 5, 2008, Pages 557-567

  Adluri, Ram Sudheer ^a   Nagarajan, Devipriya ^a   Periyaswamy, Vishwanathan ^a   Venugopal, Padmanabhan Menon ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Body weight; Ferulic acid; Histopathology; Lipid profile; Marker enzymes; Nicotine; Tissue damage

Indexed keywords

ALKALINE PHOSPHATASE; CHOLESTEROL; FATTY ACID; FERULIC ACID; LACTATE DEHYDROGENASE; NICOTINE; PHOSPHOLIPID; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ENZYME ASSAY; EXPERIMENTAL MODEL; FEMALE; HISTOPATHOLOGY; LIPID BLOOD LEVEL; LIPID KIDNEY LEVEL; LIPID LIVER LEVEL; LIPID LUNG LEVEL; LIVER PROTECTION; LUNG PROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTECTION; RAT; REGULATORY MECHANISM; RENAL PROTECTION; SMOKING; TISSUE INJURY; TISSUE LEVEL; WISTAR RAT;

ANIMALS; ANTILIPEMIC AGENTS; ANTIOXIDANTS; COUMARIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; KIDNEY; LIPID PEROXIDATION; LIPIDS; LIVER; LUNG; NICOTINE; RATS; RATS, WISTAR;

EID: 52449083855     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2008.00622.x     Document Type: Article

References (48)

1. Kuper H., Adami H.O., Boffetta P. Tobacco use, cancer causation and public health impact. J. Intern. Med. (2002) 251 455 466.
2. Kuper H., Boffetta P., Adami H.O. Tobacco use, cancer causation; association by tumor type. J. Intern. Med. (2002) 252 206 224.
3. Wynder E.L., Hoffman D. Tobacco, in : Schottenfeld D., Faumeni F. (Eds Cancer epidemiology and prevention, Saunders, New York, 1982, pp. 277 292.
4. Jaffe J.H. Drug addiction and drug abuse, in : Gilman A.G., Rail T.W., Nies A.S., Taylor P. (Eds Goodman and Gilman's the pharmacological basis of therapeutics, 8th edn, Pergamon, New York, 1985, pp. 522 573.
5. Anandatheerthavarada H.K., Williams J.F., Wecker L. The chronic administration of nicotine induces cytochrome P-450 in rat brain. J. Neurochem. 1993) 60, 1941 1944.
6. Ashakumary L., Vijayammal R.L. Lipid peroxidation in nicotine treated rats. J. Ecotoxicol. Environ. Monit. (1991) 1 283 290.
7. Bhagwat S.V., Vijayasarathy C., Raza H., Mullick J., Avadhani N.G. Preferential effects of nicotine and 4-(N-methyl-N-nitrosamine)-1-(3-pyridyl)-1- butanone on mitochondrial glutathione-S-transferase A4-4 induction and increased oxidative stress I the rat brain. Biochem. Pharmacol. (1998) 56 831 839.
8. Sudheer A.R., Kalpana C., Srinivasan M., Menon V.P. Ferulic acid modulates altered lipid profiles and prooxidant/antioxidant status in circulation during nicotine-induced toxicity: a dose-dependent study. Toxicol. Mech. Method. (2005) 15 375 381.
9. Van Ver Vaart H., Postma D.S., Timens W., ten Hacken N.H. Acute effects of cigarette smoke on inflammation and oxidative stress: a review. Thorax (2004) 59 713 721.
10. Murakami A., Nakamura Y., Koshimizu K. et al. FA15, a hydrophobic derivative of ferulic acid, suppresses inflammatory responses and skin tumor promotion: comparison with ferulic acid. Cancer Lett. (2002) 180 121 129.
11. Castelluccio C., Bolwell G.P., Gerrish C., Rice-Evans C. Differential distribution of ferulic acid to the major plasma constituents in relation to its potential as an antioxidant. Biochem. J. (1996) 316 691 694.
12. Scott B., Butler J., Halliwell B., Aruoma O.I. Evaluation of antioxidant actions of ferulic acid and catechins. Free Rad. Biol. Res. Commun. (1993) 19 241 253.
13. Kalpana C., Menon V.P. Protective effect of curcumin on circulatory lipid peroxidation and antioxidant status during nicotine-induced toxicity. Toxicol. Mech. Method. (2004) 14 339 343.
14. Rukkumani R., Aruna K., Suresh V.P., Menon V.P. Hepatoprotective role of ferulic acid: a dose dependent study. J. Med. Food (2004) 7 456 461.
15. Srinivasan M., Rukkumani R., Sudheer A.R., Menon V.P. Ferulic acid, a natural protector against carbon tetra chloride-induced toxicity. Fundam. Clin. Pharmacol. (2005) 19 491 496.
16. Young D.S., Pestaner L.C., Gibberman V. Effects of drugs on clinical laboratory tests. Clin. Chem. (1975) 21 1D 432D.
17. King E.J., Armstrong A.R. Calcium, phosphorus and phosphatase, in : Varley H. (Ed. Practical clinical biochemistry, CBS Publishers, New Delhi, 1988, pp. 458.
18. Folch J., Lees M., Solane S.G.H. A simple method for isolation and purification of total lipids from animal tissues. J. Biol. Chem. (1957) 26 497 509.
19. Allain E.C., Poon L.S., Chan C.S., Richmond W., Fu F.C. Enzymatic determination of total serum cholesterol. Clin. Chem. (1974) 20 470 475.
20. Foster C.S., Dunn O. Stable reagents for determination of serum triglycerides by a colorimetric Hantzsch condensation method. Clin. Chim. Acta (1973) 19 338 340.
21. Falholt K., Falholt W., Lund B. An easy colorimetric method for routine determination of free fatty acids in plasma. Clin. Chim. Acta (1973) 46 105.
22. Zilversmit D.B., Davis A.K. Microdetermination of plasma phospholipids by trichloroacetic acid precipitation. J. Lab. Clin. Med. (1950) 35 155.
23. Comstock G.W., Stone R.W. Changes in body weight and subcutaneous fatness related to smoking habits. Arch. Environ. Health (1972) 24 271 276.
24. Blaha V., Yang Z.J., Meguid M., Chai J.K., Zadak Z. Systemic nicotine administration suppresses food intake via reduced meal sizes in both male and female rats. Acta Medica (1998) 41 167 173.
25. Grunberg N.E., Winders S.E., Popp K.A. Sex differences in nicotine's effects on consummatory behavior and body weight in rats. Psychopharmacology (1987) 91 221 225.
26. Eliasson B., Smith U. Leptin levels in smokers and long-term users of nicotine gum. Eur. J. Clin. Invest. (1999) 29 145 152.
27. Frankish H.M., Dryden S., Wang Q., Bing C., MacFarlane I.A., Williams G. Nicotine administration reduces neuropeptide Y and neuropeptide Y mRNA concentrations in the rat hypothalamus: NPY may mediate nicotine's effects on energy balance. Brain Res. (1995) 694 139 146.
28. Winders S.E., Grunberg N.E. Effects of nicotine on body weight, food consumption, and body composition in male rats. Life Sci. (1990) 46 1523 1530.
29. Maritz G.S. Maternal nicotine exposure and carbohydrate metabolism of fetal and neonatal lung tissue: response to nicotine withdrawal. Respiration (1987) 51 232 240.
30. Graf E. Antioxidant potential of ferulic acid. Free Rad. Biol. Med. (1992) 13 453 458.
31. Rukkumani R., Aruna K., Varma P.S., Menon V.P. Influence of ferulic acid on circulatory prooxidant-antioxidant status during alcohol and PUFA induced toxicity. J. Physiol. Pharmacol. (2004) 55 551 561.
32. Manson M.M., Bal H.W., Barrett M.C. et al. Mechanism of action of dietary chemoprotective agents in rat liver: induction of phase I and II drug metabolizing enzymes and aflatoxin B1 metabolism. Carcinogenesis (1997) 18 1729 1738.
33. Yeh C.T., Yen G.C. Effects of phenolic acids on human phenolsulfotransferases in relation to their antioxidant activity. J. Agric. Food. Chem. (2003) 26 1474 1479.
34. Rawson N.S., Peto J. An overview of prognostic factors in small cell lung cancer. A report from the Subcommittee for the Management of Lung Cancer of the United Kingdom Coordinating Committee on Cancer Research. Br. J. Cancer (1990) 61 597 604.
35. Capelli A., Lusuardi M., Cerutti C.G., Donner C.F. Lung alkaline phosphatase as a marker of fibrosis in chronic interstitial disorders. Am. J. Respir. Crit. Care Med. (1997) 155 249 253.
36. Rukkumani R., Balasubashini S., Menon V.P. Protective effects of curcumin and photoirradiated curcumin on circulatory lipids and lipid peroxidation products in alcohol and polyunsaturated fatty acid-induced toxicity. Phytother Res. (2003) 17 925 929.
37. Wetscher G.J., Bagchi M., Bagchi D. et al. Free radical production in nicotine treated pancreatic tissue. Free Rad. Biol. Med. (1995) 18 877 882.
38. Yildiz D., Ercal N., Armstrong D.W. Nicotine enantiomers and oxidative stress. Toxicology (1998) 130 155 165.
39. Kanski J., Aksenova M., Stoyanova A., Butterfield D.A. Ferulic acid antioxidant protection against hydroxyl and peroxyl radical oxidation in synaptosomal and neuronal cell culture systems in vitro: structure - activity studies. J. Nutr. Biochem. (2002) 13 273 281.
40. Zhang Z., Wei T., Hou J., Li G., Yu S., Xin W. Ion-induced damage and apoptosis in cerebellar granule cells: attenuation by tetramethylpyrazine and ferulic acid. Eur. J. Pharmacol. (2003) 467 41 47.
41. Ashakumary L., Vijayammal P.L. Effect of nicotine on lipoprotein metabolism in rats. Lipids (1997) 32 311 315.
42. Ashakumary L., Vijayammal P.L. Additive effects of alcohol and nicotine on lipid peroxidation and antioxidant defense mechanism in rats. J. Appl. Toxicol. (1996) 16 305 308.
43. Chitra S., Semmalar R., Shyamala Devi C.S. Effect of fish on cigarette smoking induced dyslipidemia in rats. Indian J. Pharmacol. (2000) 32 114 119.
44. Latha M.S., Vijayammal P.L., Kurup P.A. Effect of nicotine administration on lipid metabolism in rats. Indian J. Med. Res. (1993) 98 44 49.
45. Helen A., Krishnakumar K., Vijayammal P.L., Augusti K.T. Antioxidant effect of onion oil (Allium cepa. Linn) on the damages induced by nicotine in rats as compared to alpha-tocopherol. Toxicol. Lett. (2000) 116 61 68.
46. Kim H.K., Jeog T.S., Lee M.K., Park B.Y., Choi M.S. Lipid lowering efficacy of hesperidine metabolites in high-cholesterol fed rats. Clin. Chim. Acta (2003) 327 129 137.
47. Wall M.A., Thulbeck M.W., Wohl M.E.B., Taussig L.M., Brody J.S., Buist A.S. Lung growth and development. Am. Rev. Respir. Dis. (1985) 131 191 192.
48. Oscarson M. Genetic polymorphisms in the cytochrome P4502A6 (CYP2A6) gene: implications for inter individual differences in nicotine metabolism. Drug Metab. Dispos. (2001) 29 91 95.