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Volumn 87, Issue 4, 2008, Pages 376-384

Characterization of monoclonal antibodies against the glaucoma-associated protein myocilin

Author keywords

aqueous humor; glaucoma; monoclonal antibodies; myocilin; TIGR; trabecular meshwork

Indexed keywords

IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G1 KAPPA; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN G2B KAPPA; IMMUNOGLOBULIN KAPPA CHAIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 1.1; MONOCLONAL ANTIBODY 11.1; MONOCLONAL ANTIBODY 12.10; MONOCLONAL ANTIBODY 20.1; MONOCLONAL ANTIBODY 5.1; MONOCLONAL ANTIBODY 7.1; MYOCILIN; UNCLASSIFIED DRUG;

EID: 52349116340     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2008.07.002     Document Type: Article
Times cited : (23)

References (47)
  • 1
    • 20444371356 scopus 로고    scopus 로고
    • Myocilin mutations causing glaucoma inhibit the intracellular endoproteolytic cleavage of myocilin between amino acids Arg226 and Ile227
    • Aroca-Aguilar J.D., Sanchez-Sanchez F., Ghosh S., Coca-Prados M., and Escribano J. Myocilin mutations causing glaucoma inhibit the intracellular endoproteolytic cleavage of myocilin between amino acids Arg226 and Ile227. J. Biol. Chem. 280 (2005) 21043-21051
    • (2005) J. Biol. Chem. , vol.280 , pp. 21043-21051
    • Aroca-Aguilar, J.D.1    Sanchez-Sanchez, F.2    Ghosh, S.3    Coca-Prados, M.4    Escribano, J.5
  • 2
    • 0034815847 scopus 로고    scopus 로고
    • Inefficient processing of an olfactomedin-deficient myocilin mutant: potential physiological relevance to glaucoma
    • Caballero M., and Borras T. Inefficient processing of an olfactomedin-deficient myocilin mutant: potential physiological relevance to glaucoma. Biochem. Biophys. Res. Commun. 282 (2001) 662-670
    • (2001) Biochem. Biophys. Res. Commun. , vol.282 , pp. 662-670
    • Caballero, M.1    Borras, T.2
  • 5
    • 0003089946 scopus 로고
    • Comparative aspects of the intraocular fluids
    • Davson H., and Graham Jr. L.T. (Eds), Academic Press, New York
    • Cole D.F. Comparative aspects of the intraocular fluids. In: Davson H., and Graham Jr. L.T. (Eds). The Eye (1974), Academic Press, New York 71-121
    • (1974) The Eye , pp. 71-121
    • Cole, D.F.1
  • 8
    • 33646165968 scopus 로고    scopus 로고
    • The identification of myocilin-associated proteins in the human trabecular meshwork
    • Fautsch M.P., Vrabel A.M., and Johnson D.H. The identification of myocilin-associated proteins in the human trabecular meshwork. Exp. Eye Res. 82 (2006) 1046-1052
    • (2006) Exp. Eye Res. , vol.82 , pp. 1046-1052
    • Fautsch, M.P.1    Vrabel, A.M.2    Johnson, D.H.3
  • 9
    • 0034842533 scopus 로고    scopus 로고
    • Characterization of myocilin-myocilin interactions
    • Fautsch M.P., and Johnson D.H. Characterization of myocilin-myocilin interactions. Invest. Ophthalmol. Vis. Sci. 42 (2001) 2324-2331
    • (2001) Invest. Ophthalmol. Vis. Sci. , vol.42 , pp. 2324-2331
    • Fautsch, M.P.1    Johnson, D.H.2
  • 10
    • 3843105895 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of disulfide bond use in myocilin complex formation
    • Fautsch M.P., Vrabel A.M., Peterson S.L., and Johnson D.H. In vitro and in vivo characterization of disulfide bond use in myocilin complex formation. Mol. Vis. 10 (2004) 417-425
    • (2004) Mol. Vis. , vol.10 , pp. 417-425
    • Fautsch, M.P.1    Vrabel, A.M.2    Peterson, S.L.3    Johnson, D.H.4
  • 15
    • 10944235906 scopus 로고    scopus 로고
    • Myocilin is expressed in the glomerulus of the kidney and induced in mesangioproliferative glomerulonephritis
    • Goldwich A., Baulmann D.C., Ohlmann A., Flugel-Koch C., Schocklmann H., and Tamm E.R. Myocilin is expressed in the glomerulus of the kidney and induced in mesangioproliferative glomerulonephritis. Kidney Int. 67 (2005) 140-151
    • (2005) Kidney Int. , vol.67 , pp. 140-151
    • Goldwich, A.1    Baulmann, D.C.2    Ohlmann, A.3    Flugel-Koch, C.4    Schocklmann, H.5    Tamm, E.R.6
  • 16
    • 0242500300 scopus 로고    scopus 로고
    • Perfusion with the olfactomedin domain of myocilin does not affect outflow facility
    • Goldwich A., Ethier C.R., Chan D.W.-H., and Tamm E.R. Perfusion with the olfactomedin domain of myocilin does not affect outflow facility. Invest. Ophthalmol. Vis. Sci. 44 (2003) 1953-1961
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , pp. 1953-1961
    • Goldwich, A.1    Ethier, C.R.2    Chan, D.W.-H.3    Tamm, E.R.4
  • 17
    • 0033739463 scopus 로고    scopus 로고
    • Expression of the TIGR gene in the iris, ciliary body, and trabecular meshwork of the human eye
    • Huang W., Jaroszewski J., Ortego J., Escribano J., and Coca-Prados M. Expression of the TIGR gene in the iris, ciliary body, and trabecular meshwork of the human eye. Ophthalmic Genet. 21 (2000) 155-169
    • (2000) Ophthalmic Genet. , vol.21 , pp. 155-169
    • Huang, W.1    Jaroszewski, J.2    Ortego, J.3    Escribano, J.4    Coca-Prados, M.5
  • 19
    • 25644458267 scopus 로고    scopus 로고
    • Identification of flotillin-1 as a protein interacting with myocilin: implications for the pathogenesis of primary open-angle glaucoma
    • Joe M.K., Sohn S., Choi Y.R., Park H., and Kee C. Identification of flotillin-1 as a protein interacting with myocilin: implications for the pathogenesis of primary open-angle glaucoma. Biochem. Biophys. Res. Commun. 336 (2005) 1201-1206
    • (2005) Biochem. Biophys. Res. Commun. , vol.336 , pp. 1201-1206
    • Joe, M.K.1    Sohn, S.2    Choi, Y.R.3    Park, H.4    Kee, C.5
  • 20
    • 0034014021 scopus 로고    scopus 로고
    • Localization of myocilin/trabecular meshwork inducible glucocorticoid response protein in the human eye
    • Karali A., Russell P., Stefani F.H., and Tamm E.R. Localization of myocilin/trabecular meshwork inducible glucocorticoid response protein in the human eye. Invest. Ophthalmol. Vis. Sci. 41 (2000) 729-740
    • (2000) Invest. Ophthalmol. Vis. Sci. , vol.41 , pp. 729-740
    • Karali, A.1    Russell, P.2    Stefani, F.H.3    Tamm, E.R.4
  • 21
    • 0031149050 scopus 로고    scopus 로고
    • A novel myosin-like protein (myocilin) expressed in the connecting cilium of the photoreceptor: molecular cloning, tissue expression, and chromosomal mapping
    • Kubota R., Noda S., Wang Y., Minoshima S., Asakawa S., Kudoh J., Mashima Y., Oguchi Y., and S N. A novel myosin-like protein (myocilin) expressed in the connecting cilium of the photoreceptor: molecular cloning, tissue expression, and chromosomal mapping. Genomics 41 (1997) 360-369
    • (1997) Genomics , vol.41 , pp. 360-369
    • Kubota, R.1    Noda, S.2    Wang, Y.3    Minoshima, S.4    Asakawa, S.5    Kudoh, J.6    Mashima, Y.7    Oguchi, Y.8    S, N.9
  • 24
    • 0032513020 scopus 로고    scopus 로고
    • Gene structure and properties of an olfactomedin-related glycoprotein, TIGR, cloned from glucocorticoid-induced trabecular meshwork cells
    • Nguyen T.D., Chen P., Huang W.D., Chen H., Johnson D., and Polansky J.R. Gene structure and properties of an olfactomedin-related glycoprotein, TIGR, cloned from glucocorticoid-induced trabecular meshwork cells. J. Biol. Chem. 273 (1998) 6341-6350
    • (1998) J. Biol. Chem. , vol.273 , pp. 6341-6350
    • Nguyen, T.D.1    Chen, P.2    Huang, W.D.3    Chen, H.4    Johnson, D.5    Polansky, J.R.6
  • 25
    • 0002935093 scopus 로고
    • Glucocorticoid effects on HTM cells: molecular biology approaches
    • Lutjen-Drecoll E., and Rohen J.W. (Eds), Schattaeur Press, Stuttgart
    • Nguyen T.D., Huang W., Bloom E., and Polansky J.R. Glucocorticoid effects on HTM cells: molecular biology approaches. In: Lutjen-Drecoll E., and Rohen J.W. (Eds). Basic Aspects of Glaucoma Research III (1993), Schattaeur Press, Stuttgart 331-343
    • (1993) Basic Aspects of Glaucoma Research III , pp. 331-343
    • Nguyen, T.D.1    Huang, W.2    Bloom, E.3    Polansky, J.R.4
  • 27
    • 0033753696 scopus 로고    scopus 로고
    • Localization of myocilin to the Golgi apparatus in Schlemm's canal cells
    • O'Brien E.T., Ren X.-O., and Wang Y. Localization of myocilin to the Golgi apparatus in Schlemm's canal cells. Invest. Ophthalmol. Vis. Sci. 41 (2000) 3842-3849
    • (2000) Invest. Ophthalmol. Vis. Sci. , vol.41 , pp. 3842-3849
    • O'Brien, E.T.1    Ren, X.-O.2    Wang, Y.3
  • 28
    • 0042305307 scopus 로고    scopus 로고
    • Secreted glycoprotein myocilin is a component of the myelin sheath in peripheral nerves
    • Ohlmann A., Goldwich A., Flugel-Koch C., Fuchs A.V., Schwager K., and Tamm E.R. Secreted glycoprotein myocilin is a component of the myelin sheath in peripheral nerves. Glia 43 (2003) 128-140
    • (2003) Glia , vol.43 , pp. 128-140
    • Ohlmann, A.1    Goldwich, A.2    Flugel-Koch, C.3    Fuchs, A.V.4    Schwager, K.5    Tamm, E.R.6
  • 29
    • 0030793108 scopus 로고    scopus 로고
    • Cloning and characterization of subtracted cDNAs from a human ciliary body library encoding TIGR, a protein involved in juvenile open angle glaucoma with homology to myosin and olfactomedin
    • Ortego J., Escribano J., and Coca-Prados M. Cloning and characterization of subtracted cDNAs from a human ciliary body library encoding TIGR, a protein involved in juvenile open angle glaucoma with homology to myosin and olfactomedin. FEBS Lett. 413 (1997) 349-353
    • (1997) FEBS Lett. , vol.413 , pp. 349-353
    • Ortego, J.1    Escribano, J.2    Coca-Prados, M.3
  • 32
    • 52349122760 scopus 로고    scopus 로고
    • Production and use of feline immunodeficiency virus (FIV)-based lentiviral vectors
    • Rossi J., and Friedman T. (Eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • Saenz D.T., Barraza R., Loewen N., Teo W., and Poeschla E. Production and use of feline immunodeficiency virus (FIV)-based lentiviral vectors. In: Rossi J., and Friedman T. (Eds). Gene Transfer: a Laboratory Manual (2005), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (2005) Gene Transfer: a Laboratory Manual
    • Saenz, D.T.1    Barraza, R.2    Loewen, N.3    Teo, W.4    Poeschla, E.5
  • 33
    • 34547925500 scopus 로고    scopus 로고
    • Mitchondrial association of myocilin, product of a glaucoma gene, in human trabecular meshwork cells
    • Sakai H., Shen X., Koga T., Park B.C., Noskina Y., Tibudan M., and Yue B.Y. Mitchondrial association of myocilin, product of a glaucoma gene, in human trabecular meshwork cells. J. Cell. Physiol. 213 (2007) 775-784
    • (2007) J. Cell. Physiol. , vol.213 , pp. 775-784
    • Sakai, H.1    Shen, X.2    Koga, T.3    Park, B.C.4    Noskina, Y.5    Tibudan, M.6    Yue, B.Y.7
  • 34
    • 34948890141 scopus 로고    scopus 로고
    • Characterization of the intracellular proteolytic cleavage of myocilin and identification of calpain II as a myocilin-processing protease
    • Sanchez-Sanchez F., Martinez-Redondo F., Aroca-Aguilar J.D., Coca-Prados M., and Escribano J. Characterization of the intracellular proteolytic cleavage of myocilin and identification of calpain II as a myocilin-processing protease. J. Biol. Chem. 282 (2007) 27810-27824
    • (2007) J. Biol. Chem. , vol.282 , pp. 27810-27824
    • Sanchez-Sanchez, F.1    Martinez-Redondo, F.2    Aroca-Aguilar, J.D.3    Coca-Prados, M.4    Escribano, J.5
  • 35
    • 0036904230 scopus 로고    scopus 로고
    • Expression of wild-type and truncated myocilins in trabecular meshwork cells: their subcellular localizations and cytotoxicities
    • Sohn S., Hur W., Joe M.K., K J.-H., Lee Z.-W., Ha K.-S., and Kee C. Expression of wild-type and truncated myocilins in trabecular meshwork cells: their subcellular localizations and cytotoxicities. Invest. Ophthalmol.Vis. Sci. 43 (2002) 3680-3685
    • (2002) Invest. Ophthalmol.Vis. Sci. , vol.43 , pp. 3680-3685
    • Sohn, S.1    Hur, W.2    Joe, M.K.3    K, J.-H.4    Lee, Z.-W.5    Ha, K.-S.6    Kee, C.7
  • 38
    • 31544462086 scopus 로고    scopus 로고
    • Interaction of myocilin with gamma-synuclein affects its secretion and aggregation
    • Surgucheva I., Park B.C., Yue B.Y., Tomarev S., and Surguchov A. Interaction of myocilin with gamma-synuclein affects its secretion and aggregation. Cell. Mol. Neurobiol. 25 (2005) 1009-1033
    • (2005) Cell. Mol. Neurobiol. , vol.25 , pp. 1009-1033
    • Surgucheva, I.1    Park, B.C.2    Yue, B.Y.3    Tomarev, S.4    Surguchov, A.5
  • 39
    • 0033532267 scopus 로고    scopus 로고
    • Expression pattern and in situ localization of the mouse homologue of the human MYOC (GLCIA) gene in adult brain
    • Swiderski R.E., Ying I., Cassell M.D., Alward W.L., Stone E.M., and Sheffield V.C. Expression pattern and in situ localization of the mouse homologue of the human MYOC (GLCIA) gene in adult brain. Mol. Brain Res. 68 (1999) 64-72
    • (1999) Mol. Brain Res. , vol.68 , pp. 64-72
    • Swiderski, R.E.1    Ying, I.2    Cassell, M.D.3    Alward, W.L.4    Stone, E.M.5    Sheffield, V.C.6
  • 40
    • 0036023494 scopus 로고    scopus 로고
    • Myocilin and glaucoma: facts and ideas
    • Tamm E.R. Myocilin and glaucoma: facts and ideas. Prog. Retin Eye Res. 21 4 (2002) 395-428
    • (2002) Prog. Retin Eye Res. , vol.21 , Issue.4 , pp. 395-428
    • Tamm, E.R.1
  • 42
    • 0024492203 scopus 로고
    • Protein composition of human aqueous humor: SDS-PAGE analysis of surgical and post-mortem samples
    • Tripathi R.C., Millard C.B., and Tripathi B.J. Protein composition of human aqueous humor: SDS-PAGE analysis of surgical and post-mortem samples. Exp. Eye Res. 48 (1989) 117-130
    • (1989) Exp. Eye Res. , vol.48 , pp. 117-130
    • Tripathi, R.C.1    Millard, C.B.2    Tripathi, B.J.3
  • 43
    • 0033807221 scopus 로고    scopus 로고
    • Ultrastructural localization of myocilin in human trabecular meshwork cells and tissues
    • Ueda J., Wentz-Hunter K., Cheng E., Fukuchi T., Abe H., and Yue Y. Ultrastructural localization of myocilin in human trabecular meshwork cells and tissues. J. Histochem. Cytochem. 48 (2000) 1321-1329
    • (2000) J. Histochem. Cytochem. , vol.48 , pp. 1321-1329
    • Ueda, J.1    Wentz-Hunter, K.2    Cheng, E.3    Fukuchi, T.4    Abe, H.5    Yue, Y.6
  • 44
    • 0036202868 scopus 로고    scopus 로고
    • Distribution of myocilin and extracellular matrix components in the juxtacanalicular tissue of human eyes
    • Ueda J., Wentz-Hunter K., and Yue B.Y. Distribution of myocilin and extracellular matrix components in the juxtacanalicular tissue of human eyes. Invest. Ophthalmol. Vis. Sci. 43 (2002) 1068-1076
    • (2002) Invest. Ophthalmol. Vis. Sci. , vol.43 , pp. 1068-1076
    • Ueda, J.1    Wentz-Hunter, K.2    Yue, B.Y.3
  • 45
    • 0036132219 scopus 로고    scopus 로고
    • Myocilin is associated with mitochondria in human trabecular meshwork cells
    • Wentz-Hunter K., Ueda J., Shimizu N., and Yue B.Y. Myocilin is associated with mitochondria in human trabecular meshwork cells. J. Cell. Physiol. 190 (2002) 46-53
    • (2002) J. Cell. Physiol. , vol.190 , pp. 46-53
    • Wentz-Hunter, K.1    Ueda, J.2    Shimizu, N.3    Yue, B.Y.4
  • 47
    • 26844559781 scopus 로고    scopus 로고
    • Elucidation of subfamily segregation and intramolecular coevolution of the olfactomedin-like proteins by comprehensive phylogenetic analysis and gene expression pattern assessment
    • Zeng L.-C., Han Z.-G., and Ma W.-J. Elucidation of subfamily segregation and intramolecular coevolution of the olfactomedin-like proteins by comprehensive phylogenetic analysis and gene expression pattern assessment. FEBS Lett. 579 (2005) 5443-5453
    • (2005) FEBS Lett. , vol.579 , pp. 5443-5453
    • Zeng, L.-C.1    Han, Z.-G.2    Ma, W.-J.3


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