Aqueous solubility of poorly water-soluble drugs: Prediction using similarity and quantitative structure-property relationship models

Korean Journal of Chemical Engineering

Volumn 25, Issue 4, 2008, Pages 865-873

  Kim, Junhyoung ^a   Jung, Dong Hyun ^a   Rhee, Hokyoung ^a   Choi, Seung Hoon ^a   Sung, Min Jae ^b   Choi, Woo Sik ^b  

^a Insilicotech Co Ltd   (South Korea)

^b Pusan National University   (South Korea)

Author keywords

DDB; Fine grinding; Insoluble drug; Phenytoin; QSPR; Solubility; UDCA

Indexed keywords

EID: 52349098596     PISSN: 02561115     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11814-008-0143-x     Document Type: Article

References (16)

1. rd symposium on powder science and technology, Busan, Korea (2005).
2. J. H. Kim D. H. Jung H. K. Rhee S.H. Choi M. J. Sung W. S. Choi 2008 Korean J. Chem. Eng. 25 171
3. C. A. Lipinski F. Lombardo B.W. Dominy P. J. Feeney 1997 Adv. Drug Deliv. Rev. 23 3
4. J. C. Dearden 1994 Chemom. Intell. Lab. Syst. 24 77
5. W. L. Jorgensen E. M. Duffy 2002 Adv. Drug Deliv. Rev. 54 355
6. J. Taskinen J. Yliruusi 2003 Adv. Drug Deliv. Rev. 55 1163
7. R. D. Cramer 2003 J. Med. Chem. 46 374
8. ChemIDplus, http://chem.sis.nlm.nih.gov/chemidplus/.
9. PubChem, http://pubchem.ncbi.nlm.nih.gov/.
10. Cerius2., Accelrys, San Diego, CA.
11. L. H. Hall L.B. Kier 1995 J. Chem. Inf. Comput. Sci. 35 1039
12. J. Devillers, Genetic algorithms in molecular modeling, Academic Press, San Diego (1996).
13. B. E. Mitchel P. C. Jurs 1998 J. Chem. Inf. Comput. Sci. 38 489
14. D. T. Stanton P. C. Jurs 1990 Anal. Chem. 62 2323
15. R. H. Rohrbaugh P. C. Jurs 1987 Anal. Chim. Acta 199 99
16. W. Arlt, Private communication on the prediction of thermo-physical data, University of Erlangen, Germany (2005).