New descriptors of radiation quality based on nanodosimetry, a first approach

Radiation Protection Dosimetry

Volumn 126, Issue 1-4, 2007, Pages 432-444

  Grosswendt, Bernd ^a   Pszona, S ^b   Bantsar, A ^b  

^a PHYSIKALISCH TECHNISCHE BUNDESANSTALT   (Germany)

^b SOLTAN INSTITUTE FOR NUCLEAR STUDIES   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; NITROGEN; PROTON;

ALPHA RADIATION; ARTICLE; CLUSTER ANALYSIS; DEVICE; DOSIMETRY; DOUBLE STRANDED DNA BREAK; ELECTRON; IONIZING RADIATION; MONTE CARLO METHOD; RADIATION ENERGY; SINGLE STRANDED DNA BREAK; DNA DAMAGE; EQUIPMENT; EQUIPMENT DESIGN; EVALUATION; GENETICS; INSTRUMENTATION; METHODOLOGY; NANOTECHNOLOGY; NEUTRON; PILOT STUDY; QUALITY CONTROL; RADIATION DOSE; RADIATION EXPOSURE; RADIATION MONITORING; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

DNA; DNA DAMAGE; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; NANOTECHNOLOGY; NEUTRONS; PILOT PROJECTS; QUALITY CONTROL; RADIATION DOSAGE; RADIATION MONITORING; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 52249099534     PISSN: 01448420     EISSN: None     Source Type: Journal    
DOI: 10.1093/rpd/ncm088     Document Type: Article

References (39)

1. Nikjoo, H., O'Neill, P., Terrissol, M. and Goodhead, D. T. Quantitative modelling of DNA damage using Monte Carlo track structure method. Radiat. Environ. Biophys. 38, 31-38 (1999).
2. Friedland, W., Jacob, P., Paretzke, H. G. and Stork, T. Monte Carlo simulation of the production of short DNA fragments by low-linear energy transfer radiation using higher-order DNA models. Radiat. Res. 150 170-182 (1998).
3. Amols, H. I., Wuu, C. S. and Zaider, M. On possible limitations of experimental nanodosimetry. Radiat. Prot. Dosim. 31, 125-128 (1990).
4. Shchemelinin, S., Breskin, A., Chechik, R., Pansky, A., Colautti, P., Conte, V., De Nardo, L. and Tornielli, G. Ionization measurements in small gas samples by single ion counting. Nucl. Instrum. and Meth. Phys. Res. A368, 859-861 (1996).
5. Shchemelinin, S., Breskin, A., Chechik, R., Colautti, P. and Schulte, R. W. M. First measurements of ionisation clusters on the DNA scale in a wall-less sensitive volume. Radiat. Prot. Dosim. 82, 43-50 (1999).
6. Shchemelinin, S., Garty, G., Breskin, A., Chechik, R. and Schulte, R. W. M. Ion-counting nanodosimetry: A new method for assessing radiation damage to DNA. Nucl. Instrum. and Meth. Phys. Res. A477, 527-530 (2002)
7. Garty, G., Shchemelinin, S., Breskin, A., Chechik, R., Assaf, G., Orion, I., Bashkirov, V., Schulte, R. and Grosswendt, B. The performance of a novel ion-counting nanodosimeter. Nucl. Instrum. and Meth. Phys. Res. A 492, 212-235 (2002).
8. Garty, G., Shchemelinin, S., Breskin, A., Chechik, R., Orion, I., Guedes, G. P., Schulte, R. W. M., Bashkirov, V. and Grosswendt, B. Wall-less ion-counting nanodosimetry applied to protons. Radiat. Prot. Dosim. 99, 325-330 (2002).
9. Bashkirov, V., Schulte, R., Breskin, A., Chechik, R., Schemelinin, S., Garty, G., Wroe, A., Sadrozinski, H. and Grosswendt, B. Ion-counting nanodosimeter with particle tracking capabilities. Proceedings of the 14th Symposium on Microdosimetry, to be published in Radiat. Prot. Dosim. (2006).
10. De Nardo, L., Alkaa, A., Khamphan, C., Conte, V., Colautti, P., Ségur, P. and Tornielli, G. A detector for track-nanodosimetry. Nucl. Instrum. and Meth. Phys. Res. A 484, 312-326 (2002).
11. De Nardo, L., Colautti, P., Baek, W. Y., Grosswendt, B., Alkaa, A., Ségur, P. and Tornielli, G. Track nanodosimetry of an alpha particle. Radiat. Prot. Dosim. 99, 355-358 (2002).
12. De Nardo, L., Colautti, P. and Grosswendt, B. Simulation of the measured ionisation-cluster distributions of alpha-particles in nanometric volumes of propane. Proceedings of the 14th Symposium on Microdosimetry, to be published in Radiat. Prot. Dosim. (2006).
13. Pszona, S. A Track Ion Counter. In: Booz, J., Ebert, H. G. and Smith, B. G. R (Eds) Proceedings of the Fifth Symposium on Microdosimetry. Report EUR 3452 (Luxembourg: Commission of the European Communities) pp. 1107-1121 (1976).
14. Pszona, S., Kula, J. and Marjanska, S. A new method for measuring ion clusters produced by charged particles in nanometre track sections of DNA size. Nucl. Instrum. and Meth. Phys. Res. A 447, 601-607 (2000).
15. Grosswendt, B. and Pszona, S. The formation of ionisation clusters by α-particles in 'nanometric' volumes of nitrogen: Experiment and calculation. Radiat. Prot. Dosim. 99, 331-335 (2002).
16. Bantsar, A., Grosswendt, B., Kula, J. and Pszona, S. Clusters of ionisation in nanometre targets for propane-experiments with a jet counter. Radiat. Prot. Dosim. 110, 845-850 (2004).
17. Bantsar, A., Grosswendt, B. and Pszona, S. Formation of ion clusters by low-energy electrons in nanometric targets: Experiment and Monte Carlo simulation. Proceedings of the 14th Symposium on Microdosimetry, to be published in Radiat. Prot. Dosim. (2006).
18. Grosswendt, B. Recent advances of nanodosimetry. Radiat. Prot. Dosim. 110, 789-799 (2004).
19. Grosswendt, B. Nanodosimetry, the metrological tool for connecting radiation physics with radiation biology. Proceedings of the 14th Symposium on Microdosimetry, to be published in Radiat. Prot. Dosim. (2006).
20. Grosswendt, B. Nanodosimetry, from radiation physics to radiation biology. Radiat. Prot. Dosim. 115, 1-9 (2005).
21. Brenner, D. J. and Ward, J. F. Constraints on energy deposition and target size of multiply damaged sites associated with DNA double-strand breaks. Int. J. Radiat. Biol. 61, 737-748 (1992).
22. Grosswendt, B. Formation of ionisation clusters in nanometric structures of propane-based tissue-equivalent gas or liquid water by electrons and aparticles. Radiat. Environ. Biophys. 41, 103-112 (2002).
23. Dingfelder, M., Hantke, D., Inokuti, M. and Paretzke, H. G. Electron inelastic-scattering cross sections in liquid water. Radiat. Phys. Chem. 53, 1-18 (1998).
24. Kutcher, G. J. and Green, A. E. S. A model for energy deposition in liquid water. Radiat. Res. 67, 408-425 (1976).
25. Bigildeev, E. A. and Michalik, V. Charged particle tracks in water of different phases. Monte Carlo simulation of electron tracks. Radiat. Phys. Chem. 47, 197-207 (1996).
26. Grosswendt, B. and Waibel, E. Transport of low energy electrons in nitrogen and air. Nucl. Instrum. and Meth. 155, 145-156 (1978).
27. Brenner, D. J. and Zaider, M. A computationally convenient parameterisation of experimental angular distributions of low energy electrons elastically scattered off water vapour. Phys. Med. Biol. 29 443-447 (1983).
28. ICRU. Stopping powers and ranges for protons and alpha particles. Report No. 49 (Bethesda, MD: International Commission on Radiation Units and Measurements) (1993).
29. Baek, W. Y. and Grosswendt, B. Energy dependence of W values for protons in gases. Radiat. Prot. Dosim. 52, 97-104 (1994).
30. Grosswendt, B., Baek, W. Y., Alkaa, A., Breskin, A., Colautti, P., Chechik, R., Conte, V., De Nardo, L., Ségur, P., Shchemelinin, S., Tornielli, G., Tamboul, J. Y., McDougall, I. C., Watt, D. E., Pszona, S., Kula, J. and Marjanska, S. Ionisation-pattern investigation in nanometric gas volumes. In: Colautti, P. (Ed) Radiation Quality Assessment Based on Physical Radiation Interaction at Nanometer Level. Report No. 161 (Padova, Italy: INFN-Laboratori Nazionali di Legnaro) pp. 61-70 (2000).
31. Dingfelder, M., Inokuti, M. and Paretzke, H. G. Inelastic-collision cross sections of liquid water for interactions of energetic protons. Radiat. Phys. Chem. 59, 255-275 (2000).
32. ICRU. Secondary electron spectra from charged particle interactions Report No. 55 (Bethesda, tMD: International Commission on Radiation Units and Measurements) (1996).
33. De Nardo, L., Colautti, P., Conte, V., Baek, W. Y., Grosswendt, B. and Tornielli, G. Ionization-cluster distributions of α-particles in nanometric volumes of propane: Measurement and calculation. Radiat. Environ. Biophys. 41, 235-256 (2002).
34. Grosswendt, B. and Pszona, S. The track structure of α-particles from the point of view of ionisation-cluster formation in "nanometric" volumes of nitrogen. Radiat. Environ. Biophys. 41, 91-102 (2002).
35. Nikjoo, H., Bolton, C. E., Watanabe, R., Terrissol, M., O'Neill, P. and Goodhead, D. T. Modelling of DNA damage induced by energetic electrons (100 eV to 100 keV). Radiat. Prot. Dosim. 99, 77-80 (2002).
36. Folkard, M., Prise, K. M., Vojnovic, B., Davies, S., Roper, M. J. and Michael, B. D. Measurement of DNA damage by electrons with energies between 25 and 4000 eV. Int. J. Radiat. Biol. 64, 651-658 (1993).
37. Friedland, W., Jacob, P., Bernhardt, P., Paretzke, H. G. and Dingfelder, M. Simulation of DNA damage after proton irradiation. Radiat. Res. 159, 401-410 (2003).
38. Nikjoo, H., O'Neill, P., Wilson, W. E. and Goodhead, D. T. Computational approach for determining the spectrum of DNA damage induced by ionizing radiation. Radiat. Res. 156, 577-583 (2001).
39. Friedland, W., Dingfelder, M, Jacob, P. and Paretzke, H. G. Calculated DNA double-strand break and fragmentation yields after irradiation with He ions. Radiat. Phys. Chem. 72, 279-286 (2005).