Minimally invasive Real Time Monitoring of mitochondrial NADH and tissue blood flow in the urethral wall during hemorrhage and resuscitation

Medical Science Monitor

Volumn 14, Issue 9, 2008, Pages

  Clavijo, Julio A ^a   Van Bastelaar, James ^a   Pinsky, Michael R ^a   Puyana, Juan Carlos ^a   Mayevsky, Avraham ^b  

^a PRESBYTERIAN UNIVERSITY HOSPITAL   (United States)

^b BAR ILAN UNIVERSITY   (Israel)

Author keywords

Hemorrhagic shock; Microcirculatory blood flow; Mitochondrial NADH; Resuscitation end point; Urethral wall metabolism

Indexed keywords

REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; CONTROLLED STUDY; CORRELATION ANALYSIS; ENERGY METABOLISM; FEMALE; LASER DOPPLER FLOWMETRY; MITOCHONDRION; NONHUMAN; PATIENT MONITORING; RESUSCITATION; SWINE; TISSUE BLOOD FLOW; URETHRA;

ANIMALS; CARBON DIOXIDE; FEMALE; HEMODYNAMICS; HEMORRHAGE; HYDROGEN-ION CONCENTRATION; MICROCIRCULATION; MITOCHONDRIA; MUSCLE, SKELETAL; NAD; OXIDATION-REDUCTION; OXYGEN; PARTIAL PRESSURE; REGIONAL BLOOD FLOW; RESUSCITATION; SWINE; URETHRA; URINARY BLADDER;

EID: 52249098425     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Pinsky MR, Schlichtig R: Regional oxygen deliveryin oxygen supply-dependent states. Intensive Care Med, 1990; 16(Suppl.2): S169-71
2. Abou-Khalil B, Scalea TM, Trooskin SZ et al: Hemodynamic responses to shock in young trauma patients: need for invasive monitoring. Crit Care Med, 1994; 22: 633-39
3. Kralovich KA, Morris DC, Bereczyk BE et al: Hemodynamic effects of aortic occlusion during hemorrhagicshock and cardiac arrest. J Trauma, 1997; 42: 1023-28
4. Luchette FA, Robinson BR, Friend LA et al: Adrenergic antagonists reduce lactic acidosis in response to hemorrhagic shock. J Trauma, 1999; 46: 873-80
5. Moore FA, Haenel JE, Moore EE, Whitehill TA: Incommensurate oxygen consumption in response to maximal oxygen availability predict post injury multiple organ failure. J Trauma, 1992; 33: 58-65
6. 2 Collaborative Group. N Engl J Med, 1995; 333: 1025-32
7. Hayes MA, Yau EH, Timmins AC et al: Response of critically ill patient to treatment aimed at achieving supranormal oxygen delivery and consumption. Relationship to outcome. Chest, 1993; 103: 886-95
8. Clavijo JA, Sims CA, Menconi M et al: Multiparameter monitoring of bladder wall mucosa as a surrogate of gut tissue perfusion in hemorrhagic shock. Journal of Trauma, Naple, Fl, USA: EAST; 2001
9. Mayevsky A, Doron A, Manor T et al: Cortical spreading depression recorded from the human brain using a multiparametric monitoring system. Brain Res, 1996; 740: 268-74
10. Mayevsky A, Flamm ES, Pennie W, Chance B: A fiber optic based multiprobe system for intraoperative monitoring of brain functions. SPIE Proc, 1991; 1431: 303-13
11. Mayevsky A: Biochemical and philological activities of the brain as in vivo markers of brain pathology In: Bernstein EF, Callow AD, Nicolaides AN, Shifrin EG (eds.), Cerebral, Revascularization. Med-Orion Pub, 1993; 51-69
12. Barbiro E, Zurovsky Y, Mayevsky A: Real time monitoring of rat liver energy state during ischemia. Microvasc Res, 1998; 56: 253-60
13. Meilin S, Zarchin N, Mayevsky A: Inter-relation between hemodynamic, metabolic, ionic and electrical activities during ischemia and reperfusion in the gerbil brain. Neurol Res, 1999; 21: 699-704
14. Mayevsky A, Kraut A, Manor T et al: Optical monitoring of tissue viability using reflected spectroscopy in vivo. In: Tuchin VV (ed.), Optical Technologies in Biophysics and Mediane II. SPIE. Saratov Fall Meeting 2000, 2001; 409-17
15. Mayevsky A, Nakache R, Luger-Hamer M et al: Assessment of transplanted kidney vitality by a multiparametric monitoring system. Transplant Proc, 2001; 33: 2933-34
16. Mayevsky A, Manor T, Pevzner E et al: Real-time optical monitoring of tissue vitality in vivo. SPIE, 2002; 4616: 90-39
17. th Congress, Barcelona 2002. Barcelona, 2002
18. Vollmar B, Burkhardt M, Minor T et al: A correlation of intravital microscopically assessed NADH fluorescence, tissue oxygenation, and organ function during shock and resuscitation of the rat liver. Adv Exp Med Biol, 1998; 454: 95-101
19. Kamiike W, Nakahara M, Nakao K et al: Correlation between cellular ATP level and bile excretion in the rat liver. Transplantation, 1985; 39: 50-55
20. Bowers CW, Kolton L: The efferent role of sensory axons in nerve-evoked contractions of bullfrog bladder. Neuroscience, 1987; 23: 1157-68
21. Dimagl U, Kaplan B, Jacewicz M, Pulsinelli W: Continuous measurement of cerebral cortical blood flow by laser-Doppler flowmetry in a rat stroke model. J Cereb Blood Flow Metab, 1989; 9: 589-96
22. Haberl RL, Heizer ML, Marmarou A, Ellis EF: Laser-Doppler assessment of brain microcirculation: effect of systemic alterations. Am J Physiol, 1989; 256: H1247-54
23. Wadhwani KC, Rapoport SI: Blood flow in the central and peripheral nervous systems. In: Shepherd AP, Oberg PA (eds.), Laser Doppler Blood Flowmetry Boston: Kluwer Academic Pub, 1990; 265-304
24. Mayevsky A: Brain energy metabolism of the conscious rat exposed to vanous phisiological and pathological situations. Brain Res, 1976; 113: 327-38
25. Mayevsky A: Brain NADH redox state monitored in vivo by fiber optic surface fluorometry. Brain Res Rev, 1984; 7: 49-68
26. Mayevsky A: Level of ischemia, and brain functions in the Mongolian gerbil in vivo. Brain Res, 1990; 524: 1-9
27. Mayevsky A, Rogatsky GG: Mitochondrial function in vivo evaluated by NADH fluorescence: from animal models to human studies. Am J Physiol Cell Physiol, 2007; 292: C615-40
28. Mayevsky A, Chance B: Intracellular oxidation reduction state measured in situ by a multichannel fiber-optic-surface fluorometer. Science, 1982; 217: 537-40
29. 2 as a minimally in vasive monitor of hemorrhagic shock and resuscitation. J Trauma 2004; 57: 1199-210
30. Clavijo-Alvarez JA, Sims CA, Pinsky MR, Puyana JC: Monitoring skeletal muscle and subcutaneous tissue acid-base status and oxygenation during hemorrhagic shock and resuscitation. Shock, 2005; 24: 270-75
31. Sims C, Seigne P, Menconi M et al: Skeletal muscle acidosis correlates with the severity of blood volume loss during shock and resuscitation. J Trauma, 2001; 51: 1137-45
32. Ince C, Coremans JMCC, Bruining HA: In vivo NADH fluorescence. In: Erdmann W, Bruley DF (eds.), Oxygen Transport to Tissue XIV. New York: Plenum Press, 1992; 277-96
33. Renault G, Raynal E, Sinet M et al: A laser fluorimeter for direct cardiac metabolism investigation. Optics and Laser Technology, 1982; 143-48
34. Chance B, Cohen P, Jobsis F, Schoener B: Intracellular oxidation-reduction states in vivo. Science, 1962; 137: 499-508
35. Cairns CB, Moore FA, Haenel JB et al: Evidence for early supply independent mitochondrial dysfunction in patients developing multiple organ failure after trauma. J Trauma, 1997; 42: 532-36
36. 2 saturation during resuscitation of traumatic shock monitored using near infrared spectrometry. J Trauma, 2000; 48: 637-42
37. Waxman K, Annas C, Daughters K et al: A method to determine the adequacy of resuscitation using tissue oxygen monitoring. J Trauma, 1994; 36: 852-56
38. Barbiro-Michaely E, Tolmasov M, Rinkevich-Shop S et al: Can the "brain-sparing effect" be detected in a small-animal mode? Med Sci Monit, 2007; 13(10): BR211-19