Rapid and efficient production of radiolabeled antibody conjugates using vacuum diafiltration guided by mathematical modeling

Bioconjugate Chemistry

Volumn 19, Issue 9, 2008, Pages 1927-1937

  Bartlett, Derek W ^a   Colcher, David ^a   Raubitschek, Andrew A ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BINDING ENERGY; DIGITAL STORAGE; EFFICIENCY; MEDICAL IMAGING; PURIFICATION; SHEAR FLOW;

ANTIBODY CONJUGATE; CANCER IMAGING; CANCER THERAPY; DIAFILTRATION; POSITIVE PRESSURE; PROCESSING CONDITION; PRODUCTION SCALE; RADIOLABELLING; RETENTATE; TETRAACETIC ACID;

CHELATION;

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; ANTIBODY; ANTIBODY CONJUGATE; CHELATE; HUMAN SERUM ALBUMIN; METAL; PENTETIC ACID; RITUXIMAB;

ARTICLE; BINDING AFFINITY; CANCER DIAGNOSIS; CANCER THERAPY; CONJUGATION; CONTAMINATION; DIAFILTRATION; HUMAN; ISOTOPE LABELING; MATHEMATICAL MODEL; PURIFICATION; VACUUM;

EID: 52249089816     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc800223x     Document Type: Article

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