Optimization of a novel mucoadhesive drug deliver system with ion-exchange resin core loaded with berberine hydrochloride using central composite design methodology

Yaoxue Xuebao

Volumn 43, Issue 9, 2008, Pages 963-968

  Chen, Fei ^a   Zhang, Yue ^b   Liu, Qiang ^a   Pang, Ming Zhi ^a   Yang, Xing Gang ^a   Pan, Wei San ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Berberine hydrochloride; Carbopol; Central composite design Response surface methodology; Eudragit; Ion exchange resin; Mucoadhesive microcapsule

Indexed keywords

ACRYLIC ACID DERIVATIVE; BERBERINE; CARBOMER; EUDRAGIT; ION EXCHANGE RESIN; POLYMER;

ANIMAL; ARTICLE; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; EMULSION; MALE; METABOLISM; METHODOLOGY; MICROCAPSULE; PH; RAT; SPRAGUE DAWLEY RAT; STOMACH MUCOSA; TEMPERATURE;

ACRYLATES; ANIMALS; BERBERINE; CAPSULES; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; EMULSIONS; GASTRIC MUCOSA; HYDROGEN-ION CONCENTRATION; ION EXCHANGE RESINS; MALE; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; TEMPERATURE;

EID: 52149123662     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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