Testosterone plays a limited role in cocaine-induced conditioned place preference and locomotor activity in male rats

Ethnicity and Disease

Volumn 18, Issue 2 SUPPL. 2, 2008, Pages

  Minerly, Anachristina E ^a   Russo, Scott J ^a   Kemen, Lynne M ^a   Nazarian, Arbi ^a   Wu, Hui Bing K ^a   Weierstall, Karen M ^a   Akhavan, Alaleh ^a   Jenab, Shirzad ^a   Quinones Jenab, Vanya ^a,b  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b Department of Psychology ^*  (United States)

Author keywords

Castrated; Cocaine; Gender differences; Gonadal hormones; Reward; Testosterone

Indexed keywords

COCAINE; PLACEBO; SILASTIC; TESTOSTERONE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; HORMONE ACTION; LOCOMOTION; MALE; MOTOR ACTIVITY; NONHUMAN; PLACE PREFERENCE; PSYCHOMOTOR ACTIVITY; RAT; REWARD; SEX DIFFERENCE; ANIMAL; ANIMAL BEHAVIOR; CASTRATION; DRUG EFFECT; FISCHER 344 RAT; RADIOIMMUNOASSAY; STEREOTYPY;

ANIMALS; BEHAVIOR, ANIMAL; CASTRATION; COCAINE; LOCOMOTION; MALE; RADIOIMMUNOASSAY; RATS; RATS, INBRED F344; STEREOTYPED BEHAVIOR; TESTOSTERONE;

EID: 52149103824     PISSN: 1049510X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Festa ED, Quinones-Jenab V. Gonadal hormones provide the biological basis for sex differences in behavioral responses to cocaine. Horm. Behav. 2004;46:509-519.
2. Quinones-Jenab V. Why are women from Venus and men from Mars when they abuse cocaine? Brain Res. 2006; 1126:200-203.
3. Chen R, Osterhaus G, McKerchar T, Fowler SC. The role of exogenous testosterone in cocaine-induced behavioral sensitization and plasmalemmal or vesicular dopamine uptake in castrated rats. Neurosei Lett. 2003;351: 161-164.
4. Long SF, Dennis LA, Russell RK, Benson KA, Wilson MC. Testosterone implanration reduces the motor effects of cocaine. Behav Pharmacol. 1994;5:103-106.
5. Marrinez-Sanchis S, Aragon CMC, Salvador A. Cocaine-induced locomotor activity is enhanced by exogenous testosterone. Psysiol Beh. 2002;76:605-609.
6. Febo M, Segarra AC, Nair G, Schmidt K, Doung TQ, Feris CF. The neuronal consequences of repeated cocaine exposu re revealed by funcrional MRI in awake rats. Neuropharmacology. 2005;30:936-943.
7. Chin J, Sternin O, Wu HBK, Flercher H, Perrotti LI, Jenab S, Quinones-Jenab V. Sex differences in cocaine-induced behavioral sensitization. Cell Mol Biol. 2001;47:1089-1095.
8. Markou A, Weiss F, Gold LH, Caine SB, Schulreis G, Koob GF. Animal models of drug craving. psychopharmacol. 1993;112:163-182.
9. Fesra ED, Russo SJ, Gazi FM, Niyomchai T, Kemen LM, Lin SN, Folrz R, Jenab S, Quinones-Jenab V. Sex differences in cocaine-induced behavioral responses, pharmacokinetics, and monoamine levels. Neuropharmacology. 2004;46:672-687.
10. Russo SJ, Festa ED, Fabian SJ, Gazi FM, Kraisch M, Jenab S, Quinones-Jenab V. Gonadal hormones differentially modulare cocaine-induced place preference in male and female rars. Neurosei. 2003;120:523-533.
11. Russo SJ, Jenab S, Fabian SJ, Fesra ED, Kemen LM, Quinones-Jenab V. Sex differences in the conditioned rewarding effects of cocaine. Brain Res. 2003;970:214-220.
12. Levin ER. Cellular functions of plasma membrane estrogen receptors. Steroids. 2002:67:471-475.
13. Niyomachai T, Jenab S, Festa ED, Akhavan A, Quinones-Jenab V. Effects of short- and long- term estrogen and progesterone replacement on behavioral responses and c-fos mRNA levels in female rats after acute cocaine administration. Brain Res. 2006;1126: 193-199.
14. Caine SB, Bowen CA, Yu G, Zuzga D, Negus S, Mello NK. Effect of gonadecromy and gonadal hormone replacement on cocaine self-adminisrration in female and male rats. Neuropsychopharmacol. 2004;29:929-942.
15. Clark AS, Lindenfeld RC, Gibbons CH. Anabolic-andoregenic steroids and brain reward. Pharmacol Biochem Behav. 1996;53:741-745.
16. Alexander GM, Packard MG, Hines M. Testosterone has rewarding affective properries in male rats: implications for the biological basis of sexual motivation. Beb Neurosc. 1994;108:424-428.
17. Caldarone BJ, Srock HS, Abrahamsen GC, Boechler ML, Svare BB, Resellini RA. Non- asociarive processes and place preference condirioned by testoterone. Psychol Rec. 1996:46:373-390.
18. King BE, Packard MG, Alexander GM. Affective properries of intramedial peropric area injections of testosterone in male rats. Neurosei Lett. 1999;269:149-152.
19. Packard MG, Alexander GM, Cornell AH. Rewarding affective properties of intra-nucleus accumbens injections of testosterone. Behav Neurosci. 1997; 111:219-224.
20. Packard MG, Schroeder JP, Alexander GM. Expression of resrosrerone condirioned place preference is blocked by peripheral or inrraaccumbens injecrion of alpha-flupenrhixol. Horm Behav. 1998;34:39-47.