Non-conservative surface decoration of hemoglobin: Influence of neutralization of positive charges at PEGylation sites on molecular and functional properties of PEGylated hemoglobin

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1784, Issue 10, 2008, Pages 1395-1401

  Li, Dongxia ^a   Hu, Tao ^a   Manjula, Belur N ^a   Acharya, Seetharama A ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Acylation chemistry; Blood substitute; Colloidal osmotic pressure; Hemoglobin; PEGylation

Indexed keywords

ESTER; PEGYLATED HEMOGLOBIN; POLYMERIZED HEMOGLOBIN; PROPIONIC ACID; RECOMBINANT HEMOGLOBIN; SUCCINIMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CROSS LINKING; HUMAN; MOLECULAR INTERACTION; MOLECULAR WEIGHT; ONCOTIC PRESSURE; PRIORITY JOURNAL; PROTEIN MODIFICATION; VISCOSITY;

BINDING SITES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; COLLOIDS; HEMOGLOBIN A; HEMOGLOBINS; HUMANS; PEPTIDE MAPPING; POLYETHYLENE GLYCOLS; PROTEIN DENATURATION; SURFACE PROPERTIES; VISCOSITY;

EID: 52049121510     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2008.03.014     Document Type: Article

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