The role of the Cys2-Cys7 disulfide bridge in the early steps of Islet amyloid polypeptide aggregation: A molecular dynamics study

Chemical Physics Letters

Volumn 463, Issue 4-6, 2008, Pages 396-399

  Milardi, Danilo ^a   Pappalardo, Matteo ^b   Pannuzzo, Martina ^b   Grasso, Domenico M ^b   Rosa, Carmelo La ^b  

^a CNR   (Italy)

^b UNIVERSITY OF CATANIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLOMERATION; BRIDGES; DYNAMICS; GLYCOPROTEINS; MOLECULAR DYNAMICS; QUANTUM CHEMISTRY;

DIABETES MELLITUS; DISULFIDE BRIDGES; ISOFORMS; MD SIMULATIONS; SPONTANEOUS ASSEMBLY; TYPE II;

SYSTEM STABILITY;

EID: 52049107597     PISSN: 00092614     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cplett.2008.07.110     Document Type: Article

References (49)

1. Koo E.H., Lansbury Jr. P.T., and Kelly J.W. Proc. Natl. Acad. Sci. USA 96 (1999) 9989
2. Rochet J.C., and Lansbury P.T. Curr. Opin. Struct. Biol. 10 (2000) 60
3. Hoppener J.W., Ahren B., and Lips C.J. New Engl. J. Med. 343 (2000) 411
4. Kahn S.E., Andrikopoulos S., and Verchere C.B. Diabetes 48 (1999) 241
5. Clark A., Cooper G.J.S., Lewis C.E., Morris J.F., Willis A.C., Reid K.B., and Turner R.C. Lancet 2 (1987) 231
6. Jaikaran E.T., and Clark A. Biochim. Biophys. Acta 1537 (2001) 179
7. Ashburne T., and Lansbury P.T. J. Am. Chem. Soc. 115 (1993) 11012
8. Westermark P., Engstrom U., Johnson K.H., Westermark G.T., and Betsholtz C. Proc. Natl. Acad. Sci. USA 87 (1990) 5036
9. Goldsbury C., et al. J. Struct. Biol. 130 (2000) 352
10. Aitken J.F., Loomes K.M., Konarkowska B., and Cooper G.J. Biochem. J. 374 (2003) 779
11. Bucciantini M., et al. Nature 416 (2002) 507
12. Harper J.D., and Lansbury Jr. P.T. Annu. Rev. Biochem. 66 (1997) 385
13. Green J.D., Goldsbury C., Kistler J., Cooper G.J.S., and Aebi U. J. Biol. Chem. 279 (2004) 12206
14. Kayed R., Bernhagen J., Greenfield N., Sweimeh K., Brunner H., Voelter W., and Kapurniotu A. J. Mol. Biol. 287 (1999) 781
15. Higham C.E., Jaikaran E.T., Fraser P.E., Gross M., and Clark A. FEBS Lett. 470 (2000) 55
16. Konarkowska B., Aitken J.F., Kistler J., Zhang S., and Cooper G.J.S. The FEBS J. 272 (2005) 4949
17. Koo B.W., and Miranker A.D. Prot. Sci. 14 (2005) 231
18. Abedini A., Singh G., and Raleigh D.P. Anal. Biochem. 351 (2006) 181
19. Brooks B.R., Bruccoleri R.E., Olafson B.D., States D.J., Swaminathan S., and Karplus M. J. Comput. Chem. 187 (1983) 4
20. Neria E., Fischer S., and Karplus M. J. Chem. Phys. 105 (1996) 1902
21. Ferrara P., Apostolakis J., and Caflisch A. Proteins 46 (2002) 24
22. Cecchini M., Rao F., Seeber M., and Caflisch A. J. Chem. Phys. 121 (2004) 1306
23. Gsponer J., Habertur U., and Caflisch A. Proc. Natl. Acad. Sci. USA 100 (2003) 5154
24. Ferrara P., and Caflisch A. Proc. Natl. Acad. Sci. USA 97 (2000) 10780
25. Hiltpold A., Ferrara P., Gsponer J., and Caflisch A. J. Phys. Chem. 104 (2000) 1008
26. Ferrara P., and Caflisch A. J. Mol. Biol. 306 (2001) 837
27. Gsponer J., and Caflisch A. Proc. Natl. Acad. Sci. USA 99 (2002) 6719
28. Cecchini M., Curcio R., Pappalardo M., Melki R., and Caflisch A. J. Mol. Biol. 357 (2006) 1306
29. Kabsch W., and Sander C. Biopolymers 22 (1983) 2577
30. Frishman D., and Argos P. Protein Struct. Funct. Genet. 23 (1995) 566
31. Humphrey W., Dalke A., and Schulten K. J. Mol. Graph. 14 (1996) 33
32. Pellarin R., and Caflisch A. J. Mol. Biol. 360 (2006) 882
33. Tartaglia G.G., Cavalli A., Pellarin R., and Caflisch A. Protein Sci. 14 (2005) 2723
34. Harper J.D., Wong S.S., Lieber C.M., and Lansbury P.T. Chem.Biol. 4 (1997) 119
35. Harper J.D., Lieber C.M., and Lansbury Jr. P.T. Chem. Biol. 4 (1997) 951
36. Walsh A., Lomakin G.B., Benedek A., Condron M.M., and Teplow D.B. J. Biol. Chem. 272 (1997) 22364
37. Bader R., Bamford R., Zurdo J., Luisi B.F., and Dobson C.M. J. Mol. Biol. 356 (2006) 189
38. Calamai M., Canale C., Relini A., Stefani M., Chiti F., and Dobson C.M. J. Mol. Biol. 346 (2005) 603
39. Serio T.R., et al. Science 289 (2000) 1317
40. Klimov D.K., and Thirumalai D. Structure 11 (2003) 295
41. Nguyen P.H., Li M.S., Stock G., Straub J.E., and Thirumalai D. Proc. Natl. Acad. Sci. USA 104 (2007) 111
42. Hoppener J.W.M., Ahren B., and Lips C.J.M. New Engl. J. Med. 343 (2000) 411
43. Chou P.Y., and Fasman G.D. Annu. Rev. Biochem. 47 (1978) 251
44. Minor D.L., and Kim P.S. Nature 367 (1994) 660
45. Betsholtz C., Christmansson L., Engström U., Rorsman F., Svensson V., Johnson K.H., and Westermark P. FEBS Lett. 251 (1989) 261
46. Hayden M.V., and Sowers J.R. Antioxid. Redox Sign. 9 (2007) 891
47. Sakurai K., Katoh M., Someno K., and Fujimoto Y. Biol. Pharm. Bull. 24 (2001) 876
48. Hayden M.R., and Tyagi S.C. JOP. J. Pancreas 3 (2002) 86
49. Turk J., Corbett J.A., Ramanadham S., Bohrer A., and McDaniel M.L. Biochem. Biophys. Res. Commun. 197 (1993) 1458