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Volumn 14, Issue 9, 2008, Pages 2833-2840

Posttransplant administration of cyclophosphamide and donor lymphocyte infusion induces potent antitumor immunity to solid tumor

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; IMMUNOSUPPRESSIVE AGENT;

EID: 52049107108     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-07-1742     Document Type: Article
Times cited : (15)

References (38)
  • 1
    • 0019794486 scopus 로고    scopus 로고
    • Slavin S.Weiss L, Morecki S, Weingensberg M. Eradication of murine leukemia with histoincompatible marrow grafts in mice conditioned with total lymphoid irradiation (TLI). Cancer Immunol lmmunother 1981;11: 155-8.
    • Slavin S.Weiss L, Morecki S, Weingensberg M. Eradication of murine leukemia with histoincompatible marrow grafts in mice conditioned with total lymphoid irradiation (TLI). Cancer Immunol lmmunother 1981;11: 155-8.
  • 2
    • 0025819698 scopus 로고
    • Impact of pretransplant conditioning and donor T cells on chimerism, graft-versus-host disease, graft-versus-leukemia reactivity, and tolerance after bone marrow transplantation
    • Truitt RL, Atasoylu AA. Impact of pretransplant conditioning and donor T cells on chimerism, graft-versus-host disease, graft-versus-leukemia reactivity, and tolerance after bone marrow transplantation. Blood 1991;77:2515-23.
    • (1991) Blood , vol.77 , pp. 2515-2523
    • Truitt, R.L.1    Atasoylu, A.A.2
  • 3
    • 0028901018 scopus 로고
    • Enhancement of GVL effect with rhlL-2 following BMT in a murine model for acute myeloid leukemia in SJL/J mice
    • Vourka-Karussis U, Karussis D, Ackerstein A, Slavin S. Enhancement of GVL effect with rhlL-2 following BMT in a murine model for acute myeloid leukemia in SJL/J mice. Exp Hematol 1995;23:196-201.
    • (1995) Exp Hematol , vol.23 , pp. 196-201
    • Vourka-Karussis, U.1    Karussis, D.2    Ackerstein, A.3    Slavin, S.4
  • 4
    • 0025100777 scopus 로고
    • Graft-versus-leukemia reactions after bone marrow transplantation
    • Horowitz MM, Gale RP, Sondel PM, et al. Graft-versus-leukemia reactions after bone marrow transplantation. Blood 1990;75:555-62.
    • (1990) Blood , vol.75 , pp. 555-562
    • Horowitz, M.M.1    Gale, R.P.2    Sondel, P.M.3
  • 5
    • 0034648702 scopus 로고    scopus 로고
    • Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation
    • Childs R, Chernoff A, Contentin N, et al. Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation. N Engl J Med 2000;343:750-8.
    • (2000) N Engl J Med , vol.343 , pp. 750-758
    • Childs, R.1    Chernoff, A.2    Contentin, N.3
  • 6
    • 0032006125 scopus 로고    scopus 로고
    • Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases
    • Slavin S, Nagler A, Naparstek E, et al. Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases. Blood 1998;91:756-63.
    • (1998) Blood , vol.91 , pp. 756-763
    • Slavin, S.1    Nagler, A.2    Naparstek, E.3
  • 7
    • 85003758578 scopus 로고    scopus 로고
    • Allogeneic stem-cell transplantation of renal cell cancer after nonmyeloablative chemotherapy: Feasibility, engraftment, and clinical results
    • Rini Bl, Zimmerman T, Stadler WM, Gajewski TF, Vogelzang NJ. Allogeneic stem-cell transplantation of renal cell cancer after nonmyeloablative chemotherapy: feasibility, engraftment, and clinical results. J Clin Oncol 2002;20:2017-24.
    • (2002) J Clin Oncol , vol.20 , pp. 2017-2024
    • Rini, B.1    Zimmerman, T.2    Stadler, W.M.3    Gajewski, T.F.4    Vogelzang, N.J.5
  • 8
    • 0036569579 scopus 로고    scopus 로고
    • Allogeneic blood stem cell transplantation after a reduced- intensity, preparative regimen: A pilot study in patients with refractory malignancies
    • Pedrazzoli P, Da Prada GA, Giorgiani G, et al. Allogeneic blood stem cell transplantation after a reduced- intensity, preparative regimen: a pilot study in patients with refractory malignancies. Cancer 2000;94: 2409-15.
    • (2000) Cancer , vol.94 , pp. 2409-2415
    • Pedrazzoli, P.1    Da Prada, G.A.2    Giorgiani, G.3
  • 9
    • 0036624786 scopus 로고    scopus 로고
    • Nonmyeloablative conditioning followed by hematopoietic cell allografting and donor lymphocyte infusions for patients with metastatic renal and breast cancer
    • Bregni M, Dodero A, Peccatori J, et al. Nonmyeloablative conditioning followed by hematopoietic cell allografting and donor lymphocyte infusions for patients with metastatic renal and breast cancer. Blood 2002;99:4234-6.
    • (2002) Blood , vol.99 , pp. 4234-4236
    • Bregni, M.1    Dodero, A.2    Peccatori, J.3
  • 10
    • 20844445349 scopus 로고    scopus 로고
    • Low- intensity conditioning and hematopoietic stem cell transplantation in patients with renal and colon carcinoma
    • Hentschke P, Barkholt L, Uzunel M, et al. Low- intensity conditioning and hematopoietic stem cell transplantation in patients with renal and colon carcinoma. Bone Marrow Transplant 2003;31: 253-61.
    • (2003) Bone Marrow Transplant , vol.31 , pp. 253-261
    • Hentschke, P.1    Barkholt, L.2    Uzunel, M.3
  • 11
    • 0242578094 scopus 로고    scopus 로고
    • Rapid induction of complete donor chimerism by the use of a reduced-intensity conditioning regimen composed of fludarabine and melphalan in allogeneic stem cell transplantation for metastatic solid tumors
    • Ueno NT, Cheng YC, Rondon G, et al. Rapid induction of complete donor chimerism by the use of a reduced-intensity conditioning regimen composed of fludarabine and melphalan in allogeneic stem cell transplantation for metastatic solid tumors. Blood 2003;102:3829-36.
    • (2003) Blood , vol.102 , pp. 3829-3836
    • Ueno, N.T.1    Cheng, Y.C.2    Rondon, G.3
  • 12
    • 9144234680 scopus 로고    scopus 로고
    • Adoptive immunotherapy with donor lymphocyte infusions after allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning
    • Bethge WA, Hegenbart U, Stuart MJ, et al. Adoptive immunotherapy with donor lymphocyte infusions after allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning. Blood 2004; 103:790-5.
    • (2004) Blood , vol.103 , pp. 790-795
    • Bethge, W.A.1    Hegenbart, U.2    Stuart, M.J.3
  • 13
    • 4944246445 scopus 로고    scopus 로고
    • Kinetics of engraftment in patients with hematologic malignancies given allogeneic hematopoietic cell transplantation after nonmyeloablative conditioning
    • Baron F, Baker JE, Storb R, et al. Kinetics of engraftment in patients with hematologic malignancies given allogeneic hematopoietic cell transplantation after nonmyeloablative conditioning. Blood 2004;104: 2254-62.
    • (2004) Blood , vol.104 , pp. 2254-2262
    • Baron, F.1    Baker, J.E.2    Storb, R.3
  • 14
    • 5444224775 scopus 로고    scopus 로고
    • Allogeneic hematopoietic cell transplantation for metastatic renal cell carcinoma after nonmyeloablative conditioning: Toxicity, clinical response, and immunological response to minor histocompatibility antigens
    • Tykodi SS, Warren EH, Thompson JA, et al. Allogeneic hematopoietic cell transplantation for metastatic renal cell carcinoma after nonmyeloablative conditioning: toxicity, clinical response, and immunological response to minor histocompatibility antigens. Clin Cancer Res 2004;10:7799-811.
    • (2004) Clin Cancer Res , vol.10 , pp. 7799-7811
    • Tykodi, S.S.1    Warren, E.H.2    Thompson, J.A.3
  • 15
    • 0036468924 scopus 로고    scopus 로고
    • Donor leukocyte infusion from immunized donors increases tumor vaccine efficacy after allogeneic bone marrow transplantation
    • Teshima T, Liu C, Lowler KP, Dranoff G, Ferrara JL. Donor leukocyte infusion from immunized donors increases tumor vaccine efficacy after allogeneic bone marrow transplantation. Cancer Res 2002;62: 796-800.
    • (2002) Cancer Res , vol.62 , pp. 796-800
    • Teshima, T.1    Liu, C.2    Lowler, K.P.3    Dranoff, G.4    Ferrara, J.L.5
  • 16
    • 0021984561 scopus 로고
    • Effects of in vitro depletion of T cells in HLA-identical allogeneic marrow grafts
    • Martin PJ, Hansen JA, Buckner CD, et al. Effects of in vitro depletion of T cells in HLA-identical allogeneic marrow grafts. Blood 1985;66:664-72.
    • (1985) Blood , vol.66 , pp. 664-672
    • Martin, P.J.1    Hansen, J.A.2    Buckner, C.D.3
  • 17
    • 0025678601 scopus 로고
    • Donor leukocyte transfusions for treatment of recurrent chronic myelogenous leukemia in marrow transplant patients
    • Kolb HJ, Mittermuller J, Clemm C, et al. Donor leukocyte transfusions for treatment of recurrent chronic myelogenous leukemia in marrow transplant patients. Blood 1990;76:2462-5.
    • (1990) Blood , vol.76 , pp. 2462-2465
    • Kolb, H.J.1    Mittermuller, J.2    Clemm, C.3
  • 18
    • 0033826799 scopus 로고    scopus 로고
    • Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia
    • Molldrem J J, Lee PP Wang C, et al. Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia. Nat Med 2000; 6:1018-23.
    • (2000) Nat Med , vol.6 , pp. 1018-1023
    • Molldrem, J.J.1    Lee, P.P.2    Wang, C.3
  • 20
    • 0018764352 scopus 로고
    • Antileukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow grafts
    • Weiden PL, Flournoy N, Thomas ED, et al. Antileukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow grafts. N Engl J Med 1979;300:1068-73.
    • (1979) N Engl J Med , vol.300 , pp. 1068-1073
    • Weiden, P.L.1    Flournoy, N.2    Thomas, E.D.3
  • 21
    • 0025105043 scopus 로고
    • + T cells in cyclophosphamide-induced tolerance to H-2-compati-ble, Mis-disparate antigens
    • + T cells in cyclophosphamide-induced tolerance to H-2-compati-ble, Mis-disparate antigens. J Exp Med 1990;171: 97-113.
    • (1990) J Exp Med , vol.171 , pp. 97-113
    • Eto, M.1    Mayumi, H.2    Tomita, Y.3    Yoshikai, Y.4    Nomoto, K.5
  • 22
    • 0025979008 scopus 로고
    • Specific destruction of host-reactive mature T cells of donor origin prevents graft-versus-host disease in cyclophosphamide-induced tolerant mice
    • Eto M, Mayumi H, Tomita Y, et al. Specific destruction of host-reactive mature T cells of donor origin prevents graft-versus-host disease in cyclophosphamide-induced tolerant mice. J Immunol 1991;146:1402-9.
    • (1991) J Immunol , vol.146 , pp. 1402-1409
    • Eto, M.1    Mayumi, H.2    Tomita, Y.3
  • 23
    • 27544454955 scopus 로고    scopus 로고
    • Renal cancer treatment with low levels of mixed chimerism induced by nonmyeloablative regimen using cyclophosphamide in mice
    • Harano M, Eto M, Iwai T, et al. Renal cancer treatment with low levels of mixed chimerism induced by nonmyeloablative regimen using cyclophosphamide in mice. Cancer Res 2005;65:10032-40.
    • (2005) Cancer Res , vol.65 , pp. 10032-10040
    • Harano, M.1    Eto, M.2    Iwai, T.3
  • 25
    • 1642378018 scopus 로고    scopus 로고
    • + regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative
    • + regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative. Eur J Immunol 2004;34:336-44.
    • (2004) Eur J Immunol , vol.34 , pp. 336-344
    • Ghiringhelli, F.1    Larmonier, N.2    Schmitt, E.3
  • 26
    • 4644342928 scopus 로고    scopus 로고
    • Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells
    • Turk MJ, Guevara-Patino JA, Rizzuto GA, Engelhorn ME, Houghton AN. Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells. J Exp Med 2004; 200:771 -82.
    • (2004) J Exp Med , vol.200 , pp. 771-782
    • Turk, M.J.1    Guevara-Patino, J.A.2    Rizzuto, G.A.3    Engelhorn, M.E.4    Houghton, A.N.5
  • 27
    • 10244244934 scopus 로고    scopus 로고
    • Effect of mixed chimerism on graft-versus-host disease, disease recurrence and survival after HLA-identical marrow transplantation for aplastic anemia or chronic myelogenous leukemia
    • Huss R, Deeg HJ, GooleyT, et al. Effect of mixed chimerism on graft-versus-host disease, disease recurrence and survival after HLA-identical marrow transplantation for aplastic anemia or chronic myelogenous leukemia. Bone Marrow Transplant 1996;18: 767-76.
    • (1996) Bone Marrow Transplant , vol.18 , pp. 767-776
    • Huss, R.1    Deeg, H.J.2    GooleyT3
  • 28
    • 0035865226 scopus 로고    scopus 로고
    • T cell mixed chimerism is significantly correlated to a decreased risk of acute graft-versus-host disease after allogeneic stem cell transplantation
    • Mattsson J, Uzunel M, Remberger M, Ringden O. T cell mixed chimerism is significantly correlated to a decreased risk of acute graft-versus-host disease after allogeneic stem cell transplantation. Transplantation 2001;71:433-9.
    • (2001) Transplantation , vol.71 , pp. 433-439
    • Mattsson, J.1    Uzunel, M.2    Remberger, M.3    Ringden, O.4
  • 29
    • 0141455935 scopus 로고    scopus 로고
    • Antitumor effect of donor marrow graft rejection induced by recipient leukocyte infusions in mixed chimeras prepared with nonmyeloablative conditioning: Critical role for recipient-derived IFN-γ
    • Rubio MT Kim YM, Sachs T, Mapara M, Zhao G, Sykes M. Antitumor effect of donor marrow graft rejection induced by recipient leukocyte infusions in mixed chimeras prepared with nonmyeloablative conditioning: critical role for recipient-derived IFN-γ. Blood 2003;102:2300-7.
    • (2003) Blood , vol.102 , pp. 2300-2307
    • Rubio, M.T.1    Kim, Y.M.2    Sachs, T.3    Mapara, M.4    Zhao, G.5    Sykes, M.6
  • 30
    • 0026760408 scopus 로고
    • Abnormal CD4:CD8 ratios and delayed germinal center reconstitution in lymph nodes of human graft recipients with graft-versus-host disease (GVHD): An immunohistological study
    • Sale GE, Alavaikko M, Schaefers KM, Mahan CT. Abnormal CD4:CD8 ratios and delayed germinal center reconstitution in lymph nodes of human graft recipients with graft-versus-host disease (GVHD): an immunohistological study. Exp Hematol 1992;20: 1017-21.
    • (1992) Exp Hematol , vol.20 , pp. 1017-1021
    • Sale, G.E.1    Alavaikko, M.2    Schaefers, K.M.3    Mahan, C.T.4
  • 31
    • 33947546893 scopus 로고    scopus 로고
    • Management of acute graft-versus-host disease
    • Bacigalupo A. Management of acute graft-versus-host disease. Br J Haematol 2007;137:87-98.
    • (2007) Br J Haematol , vol.137 , pp. 87-98
    • Bacigalupo, A.1
  • 32
    • 13444310503 scopus 로고    scopus 로고
    • Anti-tumour response despite loss of donor chimaerism in patients treated with non-myeloablative conditioning and allogeneic stem cell transplantation
    • Dey BR, McAfee S, Colby C, et al. Anti-tumour response despite loss of donor chimaerism in patients treated with non-myeloablative conditioning and allogeneic stem cell transplantation. Br J Haematol 2005; 128:351 -9.
    • (2005) Br J Haematol , vol.128 , pp. 351-359
    • Dey, B.R.1    McAfee, S.2    Colby, C.3
  • 33
    • 33644833910 scopus 로고    scopus 로고
    • Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
    • Motzer RJ, Michaelson MD, Redman BG, et al. Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. J Clin Oncol 2006;24:16-24.
    • (2006) J Clin Oncol , vol.24 , pp. 16-24
    • Motzer, R.J.1    Michaelson, M.D.2    Redman, B.G.3
  • 34
    • 4944249117 scopus 로고    scopus 로고
    • BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
    • Wilhelm SM, Carter C, Tang L, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 2004; 64:7099-109.
    • (2004) Cancer Res , vol.64 , pp. 7099-7109
    • Wilhelm, S.M.1    Carter, C.2    Tang, L.3
  • 35
    • 0035025762 scopus 로고    scopus 로고
    • Mixed chimerism and transplantation tolerance
    • Sykes M. Mixed chimerism and transplantation tolerance. Immunity 2001:14:417-24.
    • (2001) Immunity , vol.14 , pp. 417-424
    • Sykes, M.1
  • 36
    • 33847371148 scopus 로고    scopus 로고
    • Cyclophosphamide-using nonmyeloablative allogeneic cell therapy against renal cancer with a reduced risk of graft-versus-host disease
    • Eto M, Harano M, Tatsugami K, et al. Cyclophosphamide-using nonmyeloablative allogeneic cell therapy against renal cancer with a reduced risk of graft-versus-host disease. Clin Cancer Res 2007; 13: 1029-35.
    • (2007) Clin Cancer Res , vol.13 , pp. 1029-1035
    • Eto, M.1    Harano, M.2    Tatsugami, K.3
  • 37
    • 0036045174 scopus 로고    scopus 로고
    • Nonmyeloablative bone marrow transplantation from partially HLA-mismatched related donors using posttransplantation cyclophosphamide
    • O'Donnell PV, Luznik L, Jones RJ, et al. Nonmyeloablative bone marrow transplantation from partially HLA-mismatched related donors using posttransplantation cyclophosphamide. Biol Blood Marrow Transplant 2002;8:377-86.
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 377-386
    • O'Donnell, P.V.1    Luznik, L.2    Jones, R.J.3
  • 38
    • 34548090968 scopus 로고    scopus 로고
    • Post-transplantation high-dose cyclophosphamide is effective single agent GVHD prophylaxis that permits prompt immune reconstitution after myeloablative HLA matched related and unrelated bone marrow transplantation
    • Luznik L, Fuchs EJ, Chen AR, et al. Post-transplantation high-dose cyclophosphamide is effective single agent GVHD prophylaxis that permits prompt immune reconstitution after myeloablative HLA matched related and unrelated bone marrow transplantation. Biol Blood Marrow Transplant Suppl 2007;13:4.
    • (2007) Biol Blood Marrow Transplant Suppl , vol.13 , pp. 4
    • Luznik, L.1    Fuchs, E.J.2    Chen, A.R.3


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