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Volumn 162, Issue 1, 2008, Pages 71-76

An expression system to screen for inhibitors of parasite glucose transporters

Author keywords

Glucose transporter; High throughput screening; Leishmania mexicana; Null mutant; Plasmodium falciparum

Indexed keywords

3 O UNDEC 10 ENYL DEXTRO GLUCOSE; GLUCOSE DERIVATIVE; GLUCOSE TRANSPORTER; UNCLASSIFIED DRUG;

EID: 52049098896     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2008.07.005     Document Type: Article
Times cited : (11)

References (28)
  • 2
    • 33750705578 scopus 로고    scopus 로고
    • Antimalarial drug therapy: the role of parasite biology and drug resistance
    • Daily J.P. Antimalarial drug therapy: the role of parasite biology and drug resistance. J Clin Pharmacol 46 12 (2006) 1487-1497
    • (2006) J Clin Pharmacol , vol.46 , Issue.12 , pp. 1487-1497
    • Daily, J.P.1
  • 3
    • 0034904388 scopus 로고    scopus 로고
    • Drug resistance in Trypanosoma brucei spp., the causative agents of sleeping sickness in man and nagana in cattle
    • Matovu E., Seebeck T., Enyaru J.C., and Kaminsky R. Drug resistance in Trypanosoma brucei spp., the causative agents of sleeping sickness in man and nagana in cattle. Microbes Infect 3 9 (2001) 763-770
    • (2001) Microbes Infect , vol.3 , Issue.9 , pp. 763-770
    • Matovu, E.1    Seebeck, T.2    Enyaru, J.C.3    Kaminsky, R.4
  • 5
    • 0037388072 scopus 로고    scopus 로고
    • Genetic characterization of glucose transporter function in Leishmania mexicana
    • Burchmore R.J., Rodriguez-Contreras D., McBride K., et al. Genetic characterization of glucose transporter function in Leishmania mexicana. Proc Natl Acad Sci USA 100 7 (2003) 3901-3906
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.7 , pp. 3901-3906
    • Burchmore, R.J.1    Rodriguez-Contreras, D.2    McBride, K.3
  • 7
    • 0029593411 scopus 로고
    • Functional expression and characterization of the Trypanosoma brucei procyclic glucose transporter, THT2
    • Barrett M.P., Tetaud E., Seyfang A., Bringaud F., and Baltz T. Functional expression and characterization of the Trypanosoma brucei procyclic glucose transporter, THT2. Biochem J 312 Pt 3 (1995) 687-691
    • (1995) Biochem J , vol.312 , Issue.PART 3 , pp. 687-691
    • Barrett, M.P.1    Tetaud, E.2    Seyfang, A.3    Bringaud, F.4    Baltz, T.5
  • 8
    • 0026699609 scopus 로고
    • Aerobic fermentation of glucose by trypanosomatids
    • Cazzulo J.J. Aerobic fermentation of glucose by trypanosomatids. FASEB J 6 13 (1992) 3153-3161
    • (1992) FASEB J , vol.6 , Issue.13 , pp. 3153-3161
    • Cazzulo, J.J.1
  • 9
    • 0035062226 scopus 로고    scopus 로고
    • Glycolysis as a target for the design of new anti-trypanosome drugs
    • Verlinde C.L., Hannaert V., Blonski C., et al. Glycolysis as a target for the design of new anti-trypanosome drugs. Drug Resist Update 4 1 (2001) 50-65
    • (2001) Drug Resist Update , vol.4 , Issue.1 , pp. 50-65
    • Verlinde, C.L.1    Hannaert, V.2    Blonski, C.3
  • 10
    • 0027404170 scopus 로고
    • Differential regulation of two distinct families of glucose transporter genes in Trypanosoma brucei
    • Bringaud F., and Baltz T. Differential regulation of two distinct families of glucose transporter genes in Trypanosoma brucei. Mol Cell Biol 13 2 (1993) 1146-1154
    • (1993) Mol Cell Biol , vol.13 , Issue.2 , pp. 1146-1154
    • Bringaud, F.1    Baltz, T.2
  • 11
    • 0037934729 scopus 로고    scopus 로고
    • Validation of the hexose transporter of Plasmodium falciparum as a novel drug target
    • Joet T., Eckstein-Ludwig U., Morin C., and Krishna S. Validation of the hexose transporter of Plasmodium falciparum as a novel drug target. Proc Natl Acad Sci USA 100 13 (2003) 7476-7479
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.13 , pp. 7476-7479
    • Joet, T.1    Eckstein-Ludwig, U.2    Morin, C.3    Krishna, S.4
  • 12
    • 10744222557 scopus 로고    scopus 로고
    • Interaction of substituted hexose analogues with the Trypanosoma brucei hexose transporter
    • Azema L., Claustre S., Alric I., et al. Interaction of substituted hexose analogues with the Trypanosoma brucei hexose transporter. Biochem Pharmacol 67 3 (2004) 459-467
    • (2004) Biochem Pharmacol , vol.67 , Issue.3 , pp. 459-467
    • Azema, L.1    Claustre, S.2    Alric, I.3
  • 13
    • 0022360064 scopus 로고
    • Sequence and structure of a human glucose transporter
    • Mueckler M., Caruso C., Baldwin S.A., et al. Sequence and structure of a human glucose transporter. Science 229 4717 (1985) 941-945
    • (1985) Science , vol.229 , Issue.4717 , pp. 941-945
    • Mueckler, M.1    Caruso, C.2    Baldwin, S.A.3
  • 14
    • 33846032314 scopus 로고    scopus 로고
    • Targeting nutrient uptake mechanisms in Plasmodium
    • Kirk K., and Saliba K.J. Targeting nutrient uptake mechanisms in Plasmodium. Curr Drug Targets 8 1 (2007) 75-88
    • (2007) Curr Drug Targets , vol.8 , Issue.1 , pp. 75-88
    • Kirk, K.1    Saliba, K.J.2
  • 16
    • 0025871685 scopus 로고
    • Simultaneous transient expression assays of the trypanosomatid parasite Leishmania using beta-galactosidase and beta-glucuronidase as reporter enzymes
    • LeBowitz J.H., Coburn C.M., and Beverley S.M. Simultaneous transient expression assays of the trypanosomatid parasite Leishmania using beta-galactosidase and beta-glucuronidase as reporter enzymes. Gene 103 1 (1991) 119-123
    • (1991) Gene , vol.103 , Issue.1 , pp. 119-123
    • LeBowitz, J.H.1    Coburn, C.M.2    Beverley, S.M.3
  • 17
    • 0034051668 scopus 로고    scopus 로고
    • Four conserved cytoplasmic sequence motifs are important for transport function of the Leishmania inositol/H(+) symporter
    • Seyfang A., and Landfear S.M. Four conserved cytoplasmic sequence motifs are important for transport function of the Leishmania inositol/H(+) symporter. J Biol Chem 275 8 (2000) 5687-5693
    • (2000) J Biol Chem , vol.275 , Issue.8 , pp. 5687-5693
    • Seyfang, A.1    Landfear, S.M.2
  • 18
    • 0021085378 scopus 로고
    • High efficiency plating method for Leishmania promastigotes in semidefined or completely-defined medium
    • Iovannisci D.M., and Ullman B. High efficiency plating method for Leishmania promastigotes in semidefined or completely-defined medium. J Parasitol 69 4 (1983) 633-636
    • (1983) J Parasitol , vol.69 , Issue.4 , pp. 633-636
    • Iovannisci, D.M.1    Ullman, B.2
  • 19
    • 0023191217 scopus 로고
    • Studies on synthesis of 3-O-alkyl-d-glucose and 3-O-alkyl-d-allose derivatives and their biological activities
    • Ikekawa T., Irinoda K., Saze K., et al. Studies on synthesis of 3-O-alkyl-d-glucose and 3-O-alkyl-d-allose derivatives and their biological activities. Chem Pharm Bull (Tokyo) 35 7 (1987) 2894-2899
    • (1987) Chem Pharm Bull (Tokyo) , vol.35 , Issue.7 , pp. 2894-2899
    • Ikekawa, T.1    Irinoda, K.2    Saze, K.3
  • 20
    • 0026913634 scopus 로고
    • A chemostat study on proline uptake and metabolism of Leishmania donovani
    • Ter Kuile B.H., and Opperdoes F.R. A chemostat study on proline uptake and metabolism of Leishmania donovani. J Protozool 39 5 (1992) 555-558
    • (1992) J Protozool , vol.39 , Issue.5 , pp. 555-558
    • Ter Kuile, B.H.1    Opperdoes, F.R.2
  • 21
    • 0033548624 scopus 로고    scopus 로고
    • Intraerythrocytic Plasmodium falciparum expresses a high affinity facilitative hexose transporter
    • Woodrow C.J., Penny J.I., and Krishna S. Intraerythrocytic Plasmodium falciparum expresses a high affinity facilitative hexose transporter. J Biol Chem 274 11 (1999) 7272-7277
    • (1999) J Biol Chem , vol.274 , Issue.11 , pp. 7272-7277
    • Woodrow, C.J.1    Penny, J.I.2    Krishna, S.3
  • 22
    • 33745163279 scopus 로고    scopus 로고
    • Structure, function and biosynthesis of GLUT1
    • Mueckler M., Hresko R.C., and Sato M. Structure, function and biosynthesis of GLUT1. Biochem Soc Trans 25 3 (1997) 951-954
    • (1997) Biochem Soc Trans , vol.25 , Issue.3 , pp. 951-954
    • Mueckler, M.1    Hresko, R.C.2    Sato, M.3
  • 24
    • 0037605545 scopus 로고    scopus 로고
    • Comparative characterization of hexose transporters of Plasmodium knowlesi, Plasmodium yoelii and Toxoplasma gondii highlights functional differences within the apicomplexan family
    • Joet T., Holterman L., Stedman T.T., et al. Comparative characterization of hexose transporters of Plasmodium knowlesi, Plasmodium yoelii and Toxoplasma gondii highlights functional differences within the apicomplexan family. Biochem J 368 Pt 3 (2002) 923-929
    • (2002) Biochem J , vol.368 , Issue.PART 3 , pp. 923-929
    • Joet, T.1    Holterman, L.2    Stedman, T.T.3
  • 25
    • 0033991437 scopus 로고    scopus 로고
    • A simple colorimetric method to screen drug cytotoxicity against Leishmania using the dye Alamar Blue
    • Mikus J., and Steverding D. A simple colorimetric method to screen drug cytotoxicity against Leishmania using the dye Alamar Blue. Parasitol Int 48 3 (2000) 265-269
    • (2000) Parasitol Int , vol.48 , Issue.3 , pp. 265-269
    • Mikus, J.1    Steverding, D.2
  • 26
    • 34547525652 scopus 로고    scopus 로고
    • Interaction of O-(undec-10-en)-yl-d-glucose derivatives with the Plasmodium falciparum hexose transporter (PfHT)
    • Ionita M., Krishna S., Leo P.M., Morin C., and Patel A.P. Interaction of O-(undec-10-en)-yl-d-glucose derivatives with the Plasmodium falciparum hexose transporter (PfHT). Bioorg Med Chem Lett (2007)
    • (2007) Bioorg Med Chem Lett
    • Ionita, M.1    Krishna, S.2    Leo, P.M.3    Morin, C.4    Patel, A.P.5
  • 27
    • 24144480800 scopus 로고    scopus 로고
    • The 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum
    • Martin R.E., Henry R.I., Abbey J.L., Clements J.D., and Kirk K. The 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum. Genome Biol 6 3 (2005) R26
    • (2005) Genome Biol , vol.6 , Issue.3
    • Martin, R.E.1    Henry, R.I.2    Abbey, J.L.3    Clements, J.D.4    Kirk, K.5
  • 28
    • 0033373342 scopus 로고    scopus 로고
    • Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae
    • Wieczorke R., Krampe S., Weierstall T., Freidel K., Hollenberg C.P., and Boles E. Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464 3 (1999) 123-128
    • (1999) FEBS Lett , vol.464 , Issue.3 , pp. 123-128
    • Wieczorke, R.1    Krampe, S.2    Weierstall, T.3    Freidel, K.4    Hollenberg, C.P.5    Boles, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.