메뉴 건너뛰기




Volumn 153, Issue 1, 2007, Pages 9-18

Phenotypic characterization of a glucose transporter null mutant in Leishmania mexicana

Author keywords

Glucose transporters; Hexose transport; Leishmania mexicana; Null mutant; Oxidative stress

Indexed keywords

FRUCTOSE; GALACTOSE; GLUCOSE; GLUCOSE TRANSPORTER; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 2; GLUCOSE TRANSPORTER 3; ISOPROTEIN; MANNOSE; MUTANT PROTEIN;

EID: 34047103887     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2007.01.010     Document Type: Article
Times cited : (38)

References (35)
  • 1
    • 0030820019 scopus 로고    scopus 로고
    • Kinetoplastid glucose transporters
    • Tetaud E., Barrett M.P., Bringaud F., and Baltz T. Kinetoplastid glucose transporters. Biochem J 325 Pt 3 (1997) 569-580
    • (1997) Biochem J , vol.325 , Issue.PART 3 , pp. 569-580
    • Tetaud, E.1    Barrett, M.P.2    Bringaud, F.3    Baltz, T.4
  • 2
    • 0033903291 scopus 로고    scopus 로고
    • Genetics and biochemistry of Leishmania membrane transporters
    • Landfear S.M. Genetics and biochemistry of Leishmania membrane transporters. Curr Opin Microbiol 3 4 (2000) 417-421
    • (2000) Curr Opin Microbiol , vol.3 , Issue.4 , pp. 417-421
    • Landfear, S.M.1
  • 3
    • 0037388072 scopus 로고    scopus 로고
    • Genetic characterization of glucose transporter function in Leishmania mexicana
    • Burchmore R.J., Rodriguez-Contreras D., McBride K., et al. Genetic characterization of glucose transporter function in Leishmania mexicana. Proc Natl Acad Sci USA 100 7 (2003) 3901-3906
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.7 , pp. 3901-3906
    • Burchmore, R.J.1    Rodriguez-Contreras, D.2    McBride, K.3
  • 4
    • 0032582818 scopus 로고    scopus 로고
    • Differential regulation of multiple glucose transporter genes in Leishmania mexicana
    • Burchmore R.J., and Landfear S.M. Differential regulation of multiple glucose transporter genes in Leishmania mexicana. J Biol Chem 273 44 (1998) 29118-29126
    • (1998) J Biol Chem , vol.273 , Issue.44 , pp. 29118-29126
    • Burchmore, R.J.1    Landfear, S.M.2
  • 5
    • 0028156734 scopus 로고
    • Complete developmental cycle of Leishmania mexicana in axenic culture
    • Bates P.A. Complete developmental cycle of Leishmania mexicana in axenic culture. Parasitology 108 Pt 1 (1994) 1-9
    • (1994) Parasitology , vol.108 , Issue.PART 1 , pp. 1-9
    • Bates, P.A.1
  • 6
    • 0021085378 scopus 로고
    • High efficiency plating method for Leishmania promastigotes in semidefined or completely-defined medium
    • Iovannisci D.M., and Ullman B. High efficiency plating method for Leishmania promastigotes in semidefined or completely-defined medium. J Parasitol 69 4 (1983) 633-636
    • (1983) J Parasitol , vol.69 , Issue.4 , pp. 633-636
    • Iovannisci, D.M.1    Ullman, B.2
  • 7
    • 0036591962 scopus 로고    scopus 로고
    • Biogenesis of Leishmania-harbouring parasitophorous vacuoles following phagocytosis of the metacyclic promastigote or amastigote stages of the parasites
    • Courret N., Frehel C., Gouhier N., et al. Biogenesis of Leishmania-harbouring parasitophorous vacuoles following phagocytosis of the metacyclic promastigote or amastigote stages of the parasites. J Cell Sci 115 Pt 11 (2002) 2303-2316
    • (2002) J Cell Sci , vol.115 , Issue.PART 11 , pp. 2303-2316
    • Courret, N.1    Frehel, C.2    Gouhier, N.3
  • 8
    • 33645788058 scopus 로고    scopus 로고
    • Virulence of Leishmania major in macrophages and mice requires the gluconeogenic enzyme fructose-1,6-bisphosphatase
    • Naderer T., Ellis M.A., Sernee M.F., et al. Virulence of Leishmania major in macrophages and mice requires the gluconeogenic enzyme fructose-1,6-bisphosphatase. Proc Natl Acad Sci USA 103 14 (2006) 5502-5507
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.14 , pp. 5502-5507
    • Naderer, T.1    Ellis, M.A.2    Sernee, M.F.3
  • 9
    • 0034051668 scopus 로고    scopus 로고
    • Four conserved cytoplasmic sequence motifs are important for transport function of the Leishmania inositol/H(+) symporter
    • Seyfang A., and Landfear S.M. Four conserved cytoplasmic sequence motifs are important for transport function of the Leishmania inositol/H(+) symporter. J Biol Chem 275 8 (2000) 5687-5693
    • (2000) J Biol Chem , vol.275 , Issue.8 , pp. 5687-5693
    • Seyfang, A.1    Landfear, S.M.2
  • 10
    • 0037090631 scopus 로고    scopus 로고
    • Intracellular trafficking of glycosylphosphatidylinositol (GPI)-anchored proteins and free GPIs in Leishmania mexicana
    • Ralton J.E., Mullin K.A., and McConville M.J. Intracellular trafficking of glycosylphosphatidylinositol (GPI)-anchored proteins and free GPIs in Leishmania mexicana. Biochem J 363 Pt 2 (2002) 365-375
    • (2002) Biochem J , vol.363 , Issue.PART 2 , pp. 365-375
    • Ralton, J.E.1    Mullin, K.A.2    McConville, M.J.3
  • 11
    • 0345096563 scopus 로고    scopus 로고
    • Trypanosoma cruzi response to the oxidative stress generated by hydrogen peroxide
    • Finzi J.K., Chiavegatto C.W., Corat K.F., et al. Trypanosoma cruzi response to the oxidative stress generated by hydrogen peroxide. Mol Biochem Parasitol 133 1 (2004) 37-43
    • (2004) Mol Biochem Parasitol , vol.133 , Issue.1 , pp. 37-43
    • Finzi, J.K.1    Chiavegatto, C.W.2    Corat, K.F.3
  • 12
    • 0035898610 scopus 로고    scopus 로고
    • Disruption of mannose activation in Leishmania mexicana: GDP-mannose pyrophosphorylase is required for virulence, but not for viability
    • Garami A., and Ilg T. Disruption of mannose activation in Leishmania mexicana: GDP-mannose pyrophosphorylase is required for virulence, but not for viability. Embo J 20 14 (2001) 3657-3666
    • (2001) Embo J , vol.20 , Issue.14 , pp. 3657-3666
    • Garami, A.1    Ilg, T.2
  • 13
    • 0028339806 scopus 로고
    • Functional expression of two glucose transporter isoforms from the parasitic protozoan Leishmania enriettii
    • Langford C.K., Little B.M., Kavanaugh M.P., and Landfear S.M. Functional expression of two glucose transporter isoforms from the parasitic protozoan Leishmania enriettii. J Biol Chem 269 27 (1994) 17939-17943
    • (1994) J Biol Chem , vol.269 , Issue.27 , pp. 17939-17943
    • Langford, C.K.1    Little, B.M.2    Kavanaugh, M.P.3    Landfear, S.M.4
  • 14
    • 0029148386 scopus 로고
    • Functional expression and subcellular localization of a high-Km hexose transporter from Leishmania donovani
    • Langford C.K., Kavanaugh M.P., Stenberg P.E., Drew M.E., Zhang W., and Landfear S.M. Functional expression and subcellular localization of a high-Km hexose transporter from Leishmania donovani. Biochemistry 34 37 (1995) 11814-11821
    • (1995) Biochemistry , vol.34 , Issue.37 , pp. 11814-11821
    • Langford, C.K.1    Kavanaugh, M.P.2    Stenberg, P.E.3    Drew, M.E.4    Zhang, W.5    Landfear, S.M.6
  • 15
    • 0024959890 scopus 로고
    • Specificity and kinetics of hexose transport in Trypanosoma brucei
    • Eisenthal R., Game S., and Holman G.D. Specificity and kinetics of hexose transport in Trypanosoma brucei. Biochim Biophys Acta 985 1 (1989) 81-89
    • (1989) Biochim Biophys Acta , vol.985 , Issue.1 , pp. 81-89
    • Eisenthal, R.1    Game, S.2    Holman, G.D.3
  • 16
    • 0033525703 scopus 로고    scopus 로고
    • Roles of free GPIs in amastigotes of Leishmania
    • Mensa-Wilmot K., Garg N., McGwire B.S., et al. Roles of free GPIs in amastigotes of Leishmania. Mol Biochem Parasitol 99 1 (1999) 103-116
    • (1999) Mol Biochem Parasitol , vol.99 , Issue.1 , pp. 103-116
    • Mensa-Wilmot, K.1    Garg, N.2    McGwire, B.S.3
  • 17
    • 0021323610 scopus 로고
    • Expression of an unusual acidic glycoconjugate in Leishmania donovani
    • Turco S.J., Wilkerson M.A., and Clawson D.R. Expression of an unusual acidic glycoconjugate in Leishmania donovani. J Biol Chem 259 6 (1984) 3883-3889
    • (1984) J Biol Chem , vol.259 , Issue.6 , pp. 3883-3889
    • Turco, S.J.1    Wilkerson, M.A.2    Clawson, D.R.3
  • 18
    • 0037197847 scopus 로고    scopus 로고
    • Galactose metabolism is essential for the African sleeping sickness parasite Trypanosoma brucei
    • Roper J.R., Guther M.L., Milne K.G., and Ferguson M.A. Galactose metabolism is essential for the African sleeping sickness parasite Trypanosoma brucei. Proc Natl Acad Sci USA 99 9 (2002) 5884-5889
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.9 , pp. 5884-5889
    • Roper, J.R.1    Guther, M.L.2    Milne, K.G.3    Ferguson, M.A.4
  • 19
    • 21244496004 scopus 로고    scopus 로고
    • The suppression of galactose metabolism in procylic form Trypanosoma brucei causes cessation of cell growth and alters procyclin glycoprotein structure and copy number
    • Roper J.R., Guther M.L., Macrae J.I., et al. The suppression of galactose metabolism in procylic form Trypanosoma brucei causes cessation of cell growth and alters procyclin glycoprotein structure and copy number. J Biol Chem 280 20 (2005) 19728-19736
    • (2005) J Biol Chem , vol.280 , Issue.20 , pp. 19728-19736
    • Roper, J.R.1    Guther, M.L.2    Macrae, J.I.3
  • 20
    • 0015861774 scopus 로고
    • Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
    • Cheng Y., and Prusoff W.H. Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem Pharmacol 22 23 (1973) 3099-3108
    • (1973) Biochem Pharmacol , vol.22 , Issue.23 , pp. 3099-3108
    • Cheng, Y.1    Prusoff, W.H.2
  • 21
  • 22
  • 24
    • 13444280474 scopus 로고    scopus 로고
    • Dithiol proteins as guardians of the intracellular redox milieu in parasites: old and new drug targets in trypanosomes and malaria-causing plasmodia
    • Krauth-Siegel R.L., Bauer H., and Schirmer R.H. Dithiol proteins as guardians of the intracellular redox milieu in parasites: old and new drug targets in trypanosomes and malaria-causing plasmodia. Angew Chem Int Ed Engl 44 5 (2005) 690-715
    • (2005) Angew Chem Int Ed Engl , vol.44 , Issue.5 , pp. 690-715
    • Krauth-Siegel, R.L.1    Bauer, H.2    Schirmer, R.H.3
  • 25
    • 0036397097 scopus 로고    scopus 로고
    • Macrophage-mediated innate host defense against protozoan parasites
    • Stafford J.L., Neumann N.F., and Belosevic M. Macrophage-mediated innate host defense against protozoan parasites. Crit Rev Microbiol 28 3 (2002) 187-248
    • (2002) Crit Rev Microbiol , vol.28 , Issue.3 , pp. 187-248
    • Stafford, J.L.1    Neumann, N.F.2    Belosevic, M.3
  • 27
    • 0034825692 scopus 로고    scopus 로고
    • Life in vacuoles-nutrient acquisition by Leishmania amastigotes
    • Burchmore R.J., and Barrett M.P. Life in vacuoles-nutrient acquisition by Leishmania amastigotes. Int J Parasitol 31 12 (2001) 1311-1320
    • (2001) Int J Parasitol , vol.31 , Issue.12 , pp. 1311-1320
    • Burchmore, R.J.1    Barrett, M.P.2
  • 28
    • 0028925755 scopus 로고
    • Mycobacterium and Leishmania: stowaways in the endosomal network
    • Russell D.G. Mycobacterium and Leishmania: stowaways in the endosomal network. Trends Cell Biol 5 3 (1995) 125-128
    • (1995) Trends Cell Biol , vol.5 , Issue.3 , pp. 125-128
    • Russell, D.G.1
  • 29
    • 33746000107 scopus 로고    scopus 로고
    • Metabolic changes in glucose transporter-deficient Leishmania mexicana and parasite virulence
    • Rodriguez-Contreras D., and Landfear S.M. Metabolic changes in glucose transporter-deficient Leishmania mexicana and parasite virulence. J Biol Chem 281 29 (2006) 20068-20076
    • (2006) J Biol Chem , vol.281 , Issue.29 , pp. 20068-20076
    • Rodriguez-Contreras, D.1    Landfear, S.M.2
  • 30
    • 0026699609 scopus 로고
    • Aerobic fermentation of glucose by trypanosomatids
    • Cazzulo J.J. Aerobic fermentation of glucose by trypanosomatids. FASEB J 6 13 (1992) 3153-3161
    • (1992) FASEB J , vol.6 , Issue.13 , pp. 3153-3161
    • Cazzulo, J.J.1
  • 31
    • 33745810581 scopus 로고    scopus 로고
    • Energy metabolism of trypanosomatids: adaptation to available carbon sources
    • Bringaud F., Riviere L., and Coustou V. Energy metabolism of trypanosomatids: adaptation to available carbon sources. Mol Biochem Parasitol 149 1 (2006) 1-9
    • (2006) Mol Biochem Parasitol , vol.149 , Issue.1 , pp. 1-9
    • Bringaud, F.1    Riviere, L.2    Coustou, V.3
  • 32
    • 0031854156 scopus 로고    scopus 로고
    • Evidence that trypanothione reductase is an essential enzyme in Leishmania by targeted replacement of the tryA gene locus
    • Tovar J., Wilkinson S., Mottram J.C., and Fairlamb A.H. Evidence that trypanothione reductase is an essential enzyme in Leishmania by targeted replacement of the tryA gene locus. Mol Microbiol 29 2 (1998) 653-660
    • (1998) Mol Microbiol , vol.29 , Issue.2 , pp. 653-660
    • Tovar, J.1    Wilkinson, S.2    Mottram, J.C.3    Fairlamb, A.H.4
  • 33
    • 4444278762 scopus 로고    scopus 로고
    • A trypanothione-dependent glyoxalase I with a prokaryotic ancestry in Leishmania major
    • Vickers T.J., Greig N., and Fairlamb A.H. A trypanothione-dependent glyoxalase I with a prokaryotic ancestry in Leishmania major. Proc Natl Acad Sci USA 101 36 (2004) 13186-13191
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.36 , pp. 13186-13191
    • Vickers, T.J.1    Greig, N.2    Fairlamb, A.H.3
  • 34
    • 0032852260 scopus 로고    scopus 로고
    • Glycoconjugates in Leishmania infectivity
    • Descoteaux A., and Turco S.J. Glycoconjugates in Leishmania infectivity. Biochim Biophys Acta 1455 2/3 (1999) 341-352
    • (1999) Biochim Biophys Acta , vol.1455 , Issue.2-3 , pp. 341-352
    • Descoteaux, A.1    Turco, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.