Identification and control of a degradation product in Avapro™ film-coated tablet: Low dose formulation

Pharmaceutical Development and Technology

Volumn 13, Issue 5, 2008, Pages 393-399

  Wang, George ^a   Fiske, John D ^a   Jennings, Scott P ^a   Tomasella, Frank P ^a   Palaniswamy, Venkatapuram A ^a   Ray, Kenneth L ^b  

^a BRISTOL MYERS SQUIBB   (United States)

^b Novatia   (United States)

Author keywords

Avapro; Formaldehyde; Formaldehyde degradant; Kinetics; Polyethylene glycol

Indexed keywords

IRBESARTAN;

ARTICLE; CHEMICAL REACTION KINETICS; DRUG DEGRADATION; DRUG IMPURITY; DRUG STABILITY; DRUG STORAGE; FILM COATING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; SHELF LIFE; TABLET FORMULATION; TANDEM MASS SPECTROMETRY;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; BIPHENYL COMPOUNDS; CHROMATOGRAPHY, LIQUID; DRUG INCOMPATIBILITY; DRUG STABILITY; DRUG STORAGE; EXCIPIENTS; FORMALDEHYDE; POLYETHYLENE GLYCOLS; TABLETS; TANDEM MASS SPECTROMETRY; TEMPERATURE; TETRAZOLES;

EID: 51949102878     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.1080/10837450802244918     Document Type: Article

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