-
1
-
-
3142729014
-
Sulfur amino acid metabolism: Pathways for production and removal of homocysteine and cysteine
-
10.1146/annurev.nutr.24.012003.132418 15189131
-
Stipanuk MH Sulfur amino acid metabolism: Pathways for production and removal of homocysteine and cysteine Annu Rev Nutr 2004, 24:539-77 10.1146/annurev.nutr.24.012003.132418 15189131
-
(2004)
Annu Rev Nutr
, vol.24
, pp. 539-577
-
-
Stipanuk, M.H.1
-
2
-
-
0029049553
-
A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
-
10.1038/ng0595-111 7647779
-
Frosst P Blom HJ Milos R Goyette P Sheppard CA Matthews RG Boers GJH den Heijer M Kluitmans LAJ ven den Heuve LP Rozen R A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase Nat Genet 1995, 10:111-113 10.1038/ ng0595-111 7647779
-
(1995)
Nat Genet
, vol.10
, pp. 111-113
-
-
Frosst, P.1
Blom, H.J.2
Milos, R.3
Goyette, P.4
Sheppard, C.A.5
Matthews, R.G.6
Boers, G.J.H.7
den Heijer, M.8
Kluitmans, L.A.J.9
ven den Heuve, L.P.10
Rozen, R.11
-
3
-
-
0031971515
-
A second common mutation in the methylenetetrahydrofolate reductase gene: An additional risk factor for neural-tube defects?
-
1377082 9545395 10.1086/301825
-
Put van der NM Gabreels F Stevens EM Smeitink JA Trijbels FJ Eskes TK Heuvel van den LP Blom HJ A second common mutation in the methylenetetrahydrofolate reductase gene: An additional risk factor for neural-tube defects? Am J Hum Genet 1998, 62:1044-1051 1377082 9545395 10.1086/301825
-
(1998)
Am J Hum Genet
, vol.62
, pp. 1044-1051
-
-
Put van der, N.M.1
Gabreels, F.2
Stevens, E.M.3
Smeitink, J.A.4
Trijbels, F.J.5
Eskes, T.K.6
Heuvel van den, L.P.7
Blom, H.J.8
-
4
-
-
0035864635
-
Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction
-
10.1016/S0021-9150(00)00469-X 11257268
-
Chen J Stampfer MJ Ma J Selhub J Malinow MR Hennekens CH Hunter DJ Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction Atherosclerosis 2001, 154:667-672 10.1016/ S0021-9150(00)00469-X 11257268
-
(2001)
Atherosclerosis
, vol.154
, pp. 667-672
-
-
Chen, J.1
Stampfer, M.J.2
Ma, J.3
Selhub, J.4
Malinow, M.R.5
Hennekens, C.H.6
Hunter, D.J.7
-
5
-
-
13144282730
-
Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria
-
19694 9501215 10.1073/pnas.95.6.3059
-
Leclerc D Wilson A Dumas R Gafuik C Song D Watkins D Heng HH Rommens JM Scherer SW Rosenblatt DS Gravel RA Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria Proc Natl Acad Sci USA 1998, 95:3059-3064 19694 9501215 10.1073/pnas.95.6.3059
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3059-3064
-
-
Leclerc, D.1
Wilson, A.2
Dumas, R.3
Gafuik, C.4
Song, D.5
Watkins, D.6
Heng, H.H.7
Rommens, J.M.8
Scherer, S.W.9
Rosenblatt, D.S.10
Gravel, R.A.11
-
6
-
-
0035865701
-
Transcobalamin codon 259 polymorphism in HT-29 and Caco-2 cells and in Caucasians: Relation to transcobalamin and homocysteine concentration in blood
-
10.1182/blood.V97.4.1092 11159542
-
Namour F Olivier J Abdelmouttaleb I Adjalla C Debard R Salvat C Guéant J Transcobalamin codon 259 polymorphism in HT-29 and Caco-2 cells and in Caucasians: Relation to transcobalamin and homocysteine concentration in blood Blood 2001, 97:1092-1098 10.1182/ blood.V97.4.1092 11159542
-
(2001)
Blood
, vol.97
, pp. 1092-1098
-
-
Namour, F.1
Olivier, J.2
Abdelmouttaleb, I.3
Adjalla, C.4
Debard, R.5
Salvat, C.6
Guéant, J.7
-
8
-
-
0028845307
-
Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men
-
10.1016/S0140-6736(95)92407-8 7475822
-
Perry IJ Refsum H Morris RW Ebrahim SB Ueland PM Shaper AG Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men Lancet 1995, 346:1395-1398 10.1016/ S0140-6736(95)92407-8 7475822
-
(1995)
Lancet
, vol.346
, pp. 1395-1398
-
-
Perry, I.J.1
Refsum, H.2
Morris, R.W.3
Ebrahim, S.B.4
Ueland, P.M.5
Shaper, A.G.6
-
9
-
-
34247877467
-
Vascular and Cellular Stress in Inflammatory Bowel Disease: Revisiting the Role of Homocysteine
-
10.1111/j.1572-0241.2007.01170.x
-
Peyrin-Biroulet L Rodriguez-Guéant RM Chamaillard M Desreumaux P Xia B Bronowicki JP Bigard MA Guéant JL Vascular and Cellular Stress in Inflammatory Bowel Disease: Revisiting the Role of Homocysteine Am J Gastroenterol 2007, 102:1-8 10.1111/ j.1572-0241.2007.01170.x
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 1-8
-
-
Peyrin-Biroulet, L.1
Rodriguez-Guéant, R.M.2
Chamaillard, M.3
Desreumaux, P.4
Xia, B.5
Bronowicki, J.P.6
Bigard, M.A.7
Guéant, J.L.8
-
10
-
-
0032810850
-
Increased prevalence of methylenetetrahydrofolate reductase C677T variant in patients with inflammatory bowel disease, and its clinical implications
-
1727640 10446107
-
Mahmud N Molloy A McPartlin J Corbally R Whitehead AS Scott JM Weir DG Increased prevalence of methylenetetrahydrofolate reductase C677T variant in patients with inflammatory bowel disease, and its clinical implications Gut 1999, 45:389-394 1727640 10446107
-
(1999)
Gut
, vol.45
, pp. 389-394
-
-
Mahmud, N.1
Molloy, A.2
McPartlin, J.3
Corbally, R.4
Whitehead, A.S.5
Scott, J.M.6
Weir, D.G.7
-
11
-
-
0034827834
-
Hyperhomocysteinemia and prevalence of polymorphisms of homocysteine metabolism-related enzymes in patients with inflammatory bowel disease
-
10.1111/j.1572-0241.2001.04127.x 11569694
-
Papa A De Stefano V Danese S Chiusolo P Persichilli S Casorelli I Zappacosta B Giardina B Gasbarrini A Leone G Gasbarrini G Hyperhomocysteinemia and prevalence of polymorphisms of homocysteine metabolism-related enzymes in patients with inflammatory bowel disease Am J Gastroenterol 2001, 96:2677-2682 10.1111/j.1572-0241.2001.04127.x 11569694
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 2677-2682
-
-
Papa, A.1
De Stefano, V.2
Danese, S.3
Chiusolo, P.4
Persichilli, S.5
Casorelli, I.6
Zappacosta, B.7
Giardina, B.8
Gasbarrini, A.9
Leone, G.10
Gasbarrini, G.11
-
12
-
-
0034933207
-
Hyperhomocysteinemia and inflammatory bowel disease: Prevalence and predictors in a cross-sectional study
-
10.1111/j.1572-0241.2001.03950.x 11467646
-
Romagnuolo J Fedorak RN Dias VC Bamforth F Teltscher M Hyperhomocysteinemia and inflammatory bowel disease: Prevalence and predictors in a cross-sectional study Am J Gastroenterol 2001, 96:2143-2149 10.1111/j.1572-0241.2001.03950.x 11467646
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 2143-2149
-
-
Romagnuolo, J.1
Fedorak, R.N.2
Dias, V.C.3
Bamforth, F.4
Teltscher, M.5
-
13
-
-
4244007411
-
Homocysteine and MTHFR C677T variant in inflammatory bowel disease
-
Portela E Lerias C Palmeiro A Homocysteine and MTHFR C677T variant in inflammatory bowel disease Gut 1999, 45(Suppl):A15
-
(1999)
Gut
, vol.45
, Issue.SUPPL.
-
-
Portela, E.1
Lerias, C.2
Palmeiro, A.3
-
14
-
-
0343807499
-
Prothrombotic inherited abnormalities other than factor V Leiden mutation do not play a role in venous thrombosis in inflammatory bowel disease
-
11374681
-
Guedon C Le Cam-Duchez V Lalaude O Ménard JF Lerebourgs E Borg JY Prothrombotic inherited abnormalities other than factor V Leiden mutation do not play a role in venous thrombosis in inflammatory bowel disease Am J Gastroenterol 2001, 96:1448-1454 11374681
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 1448-1454
-
-
Guedon, C.1
Le Cam-Duchez, V.2
Lalaude, O.3
Ménard, J.F.4
Lerebourgs, E.5
Borg, J.Y.6
-
15
-
-
0033869354
-
Inflammatory bowel diseases are not associated with major hereditary conditions predisposing to thrombosis
-
10.1023/A:1005541028045 10961731
-
Vecchi M Sacchi E Saibeni S Meucci G Tagliabue L Duca F De Franchis R Inflammatory bowel diseases are not associated with major hereditary conditions predisposing to thrombosis Dig Dis Sci 2000, 45:1465-1469 10.1023/A:1005541028045 10961731
-
(2000)
Dig Dis Sci
, vol.45
, pp. 1465-1469
-
-
Vecchi, M.1
Sacchi, E.2
Saibeni, S.3
Meucci, G.4
Tagliabue, L.5
Duca, F.6
De Franchis, R.7
-
16
-
-
17644380328
-
Genotypes 677TT and 677CT+1298AC of methylenetetrahydrofolate reductase are associated with the severity of ulcerative colitis in central China
-
1774509 15831933 10.1136/gut.2004.062539
-
Chen M Xia B Rodriguez-Gueant RM Bigard M Guéant JL Genotypes 677TT and 677CT+1298AC of methylenetetrahydrofolate reductase are associated with the severity of ulcerative colitis in central China Gut 2005, 54:733-734 1774509 15831933 10.1136/gut.2004.062539
-
(2005)
Gut
, vol.54
, pp. 733-734
-
-
Chen, M.1
Xia, B.2
Rodriguez-Gueant, R.M.3
Bigard, M.4
Guéant, J.L.5
-
17
-
-
0842265263
-
High prevalence of combined thrombophilic abnormalities in patients with inflammatory bowel disease
-
10.1097/00042737-200311000-00002 14560147
-
Magro F Dinis-Ribeiro M Araujo FM Pereira P Fraga MC Cunha-Ribeiro LM Tomé-Ribeiro A High prevalence of combined thrombophilic abnormalities in patients with inflammatory bowel disease Eur J Gastroenterol Hepatol 2003, 15:1157-1163 10.1097/ 00042737-200311000-00002 14560147
-
(2003)
Eur J Gastroenterol Hepatol
, vol.15
, pp. 1157-1163
-
-
Magro, F.1
Dinis-Ribeiro, M.2
Araujo, F.M.3
Pereira, P.4
Fraga, M.C.5
Cunha-Ribeiro, L.M.6
Tomé-Ribeiro, A.7
-
18
-
-
33645652119
-
Prevalence of methylenetetrahydrofolate reductase 677T and 1298C alleles and folate status: A comparative study among Mexican, West African and West European populations
-
16522920
-
Guéant-Rodriguez RM Guéant JL Debard R Thirion S Hong LX Bronowicki JP Namour F Chabi NW Sanni A Anello G Bosco P Romano C Amouzou E Arrieta HR Sanchez BE Romano A Herbeth B Guilland JC Mutchinick OM Prevalence of methylenetetrahydrofolate reductase 677T and 1298C alleles and folate status: A comparative study among Mexican, West African and West European populations Am J Clin Nutr 2006, 83:701-707 16522920
-
(2006)
Am J Clin Nutr
, vol.83
, pp. 701-707
-
-
Guéant-Rodriguez, R.M.1
Guéant, J.L.2
Debard, R.3
Thirion, S.4
Hong, L.X.5
Bronowicki, J.P.6
Namour, F.7
Chabi, N.W.8
Sanni, A.9
Anello, G.10
Bosco, P.11
Romano, C.12
Amouzou, E.13
Arrieta, H.R.14
Sanchez, B.E.15
Romano, A.16
Herbeth, B.17
Guilland, J.C.18
Mutchinick, O.M.19
-
19
-
-
34250715385
-
Environmental influence on the world-wide prevalence of a 776C>G variant in the transcobalamin gene (TCN2)
-
10.1136/jmg.2006.048041 17220211
-
Guéant JL Chabi N Guéant-Rodriguez RM Mutchinick O Debard R Payet C Lu X Villaume C Bronowicki JP Quadros EV Sanni A Amouzou E Xia B Chen M Anello G Bosco P Romano C Arrieta HR Sanchez BE Romano A Herbeth B Anwar W Namour F Environmental influence on the world-wide prevalence of a 776C>G variant in the transcobalamin gene (TCN2) J Med Genet 2007, 44:363-7 10.1136/jmg.2006.048041 17220211
-
(2007)
J Med Genet
, vol.44
, pp. 363-367
-
-
Guéant, J.L.1
Chabi, N.2
Guéant-Rodriguez, R.M.3
Mutchinick, O.4
Debard, R.5
Payet, C.6
Lu, X.7
Villaume, C.8
Bronowicki, J.P.9
Quadros, E.V.10
Sanni, A.11
Amouzou, E.12
Xia, B.13
Chen, M.14
Anello, G.15
Bosco, P.16
Romano, C.17
Arrieta, H.R.18
Sanchez, B.E.19
Romano, A.20
Herbeth, B.21
Anwar, W.22
Namour, F.23
more..
-
20
-
-
33646778482
-
The Montreal classification of inflammatory bowel disease: Controversies, consensus, and implications
-
10.1136/gut.2005.082909 16698746
-
Satsangi J Silverberg MS Vermaire S Colombel JF The Montreal classification of inflammatory bowel disease: Controversies, consensus, and implications Gut 2006, 55:749-753 10.1136/gut.2005.082909 16698746
-
(2006)
Gut
, vol.55
, pp. 749-753
-
-
Satsangi, J.1
Silverberg, M.S.2
Vermaire, S.3
Colombel, J.F.4
-
21
-
-
0035313224
-
Biological and clinical implications of the MTHFR C677T polymorphism
-
10.1016/S0165-6147(00)01675-8 11282420
-
Ueland PM Hustad S Schneede J Refsum H Vollset SE Biological and clinical implications of the MTHFR C677T polymorphism Trends Pharmacol Sci 2001, 22:195-201 10.1016/S0165-6147(00)01675-8 11282420
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 195-201
-
-
Ueland, P.M.1
Hustad, S.2
Schneede, J.3
Refsum, H.4
Vollset, S.E.5
-
22
-
-
22144447861
-
Antioxidants as novel therapy in a murine model of colitis
-
10.1016/j.jnutbio.2004.09.007 15866230
-
Oz HS Chen TS McClain CJ de Villiers WJ Antioxidants as novel therapy in a murine model of colitis J Nutr Biochem 2005, 16:297-304 10.1016/ j.jnutbio.2004.09.007 15866230
-
(2005)
J Nutr Biochem
, vol.16
, pp. 297-304
-
-
Oz, H.S.1
Chen, T.S.2
McClain, C.J.3
de Villiers, W.J.4
-
23
-
-
10744228304
-
Genetic determinants of folate and vitamin B12 metabolism: A common pathway in neural tube defect and Down syndrome?
-
10.1515/CCLM.2003.226 14656028
-
Guéant JL Guéant-Rodriguez RM Anello G Bosco P brunaud L Romano C Ferri R Romano A Candito M Namour B Genetic determinants of folate and vitamin B12 metabolism: A common pathway in neural tube defect and Down syndrome? Clin Chem Lab Med 2003, 41:1473-1477 10.1515/ CCLM.2003.226 14656028
-
(2003)
Clin Chem Lab Med
, vol.41
, pp. 1473-1477
-
-
Guéant, J.L.1
Guéant-Rodriguez, R.M.2
Anello, G.3
Bosco, P.4
brunaud, L.5
Romano, C.6
Ferri, R.7
Romano, A.8
Candito, M.9
Namour, B.10
-
24
-
-
51949104961
-
Meta-analysis of MTHFR 677C→T polymorphism and coronary heart disease: Does totality of evidence support causal role for homocysteine and preventive potential of folate?
-
Lewis SJ Ebrahim S Smith GD Meta-analysis of MTHFR 677C→T polymorphism and coronary heart disease: Does totality of evidence support causal role for homocysteine and preventive potential of folate? Br Med J 2005, 10:1136
-
(2005)
Br Med J
, vol.10
, pp. 1136
-
-
Lewis, S.J.1
Ebrahim, S.2
Smith, G.D.3
-
25
-
-
0036145049
-
Hyperhomocysteinaemia, coagulation pathway activation and thrombophilia in patients with inflammatory bowel disease
-
10.1080/003655202753387374 11843038
-
Bjerregaard LT Nederby NJ Fredholm L Brandskund I Munkholm P Hey H Hyperhomocysteinaemia, coagulation pathway activation and thrombophilia in patients with inflammatory bowel disease Scand J Gastroenterol 2002, 37:62-67 10.1080/003655202753387374 11843038
-
(2002)
Scand J Gastroenterol
, vol.37
, pp. 62-67
-
-
Bjerregaard, L.T.1
Nederby, N.J.2
Fredholm, L.3
Brandskund, I.4
Munkholm, P.5
Hey, H.6
-
26
-
-
39049085716
-
Association of MTRR 66A > G Polymorphism With Superoxide Dismutase and Disease Activity in Patients With Crohn's Disease
-
10.1111/j.1572-0241.2007.01573.x 17925002
-
Peyrin-Biroulet L Guéant-Rodriguez RM Chen M Bronowicki JP Bigard MA Guéant JL Association of MTRR 66A > G Polymorphism With Superoxide Dismutase and Disease Activity in Patients With Crohn's Disease Am J Gastroenterol 2008, 103:399-406 10.1111/ j.1572-0241.2007.01573.x 17925002
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 399-406
-
-
Peyrin-Biroulet, L.1
Guéant-Rodriguez, R.M.2
Chen, M.3
Bronowicki, J.P.4
Bigard, M.A.5
Guéant, J.L.6
-
27
-
-
34547146470
-
Folate deficiency and plasma homocysteine during increased oxidative stress
-
10.1056/NEJMc066569 17652662
-
Rogers EJ Chen S Chan A Folate deficiency and plasma homocysteine during increased oxidative stress N Engl J Med 2007, 357:421-2 10.1056/ NEJMc066569 17652662
-
(2007)
N Engl J Med
, vol.357
, pp. 421-422
-
-
Rogers, E.J.1
Chen, S.2
Chan, A.3
-
29
-
-
28044454730
-
Genetic variation in the MTHFR gene influences thiopurine methyltransferase activity
-
10.1373/clinchem.2005.053157 16306100
-
Arenas M Simpson G Lewis CM Shobowale-Bakre el-M Escuredo E Fairbanks LD Duley JA Ansari A Sanderson JD Marinaki AM Genetic variation in the MTHFR gene influences thiopurine methyltransferase activity Clin Chem 2005, 51:2371-4 10.1373/clinchem.2005.053157 16306100
-
(2005)
Clin Chem
, vol.51
, pp. 2371-2374
-
-
Arenas, M.1
Simpson, G.2
Lewis, C.M.3
Shobowale-Bakre, El.-M.4
Escuredo, E.5
Fairbanks, L.D.6
Duley, J.A.7
Ansari, A.8
Sanderson, J.D.9
Marinaki, A.M.10
-
30
-
-
0031593869
-
High prevalence of hyperhomocysteinemia in patients with inflammatory bowel disease: A pathogenic link with thromboembolic complications?
-
9798965
-
Cattaneo M Vecchi M Zighetti ML Saibeni S Martinelli I Omodei P Mannucci PM de Franchis R High prevalence of hyperhomocysteinemia in patients with inflammatory bowel disease: A pathogenic link with thromboembolic complications? Thromb Haemost 1998, 80:542-545 9798965
-
(1998)
Thromb Haemost
, vol.80
, pp. 542-545
-
-
Cattaneo, M.1
Vecchi, M.2
Zighetti, M.L.3
Saibeni, S.4
Martinelli, I.5
Omodei, P.6
Mannucci, P.M.7
de Franchis, R.8
-
32
-
-
33846036404
-
Inflammation and Coagulation in Inflammatory Bowel Disease: The Clot Thickens
-
10.1111/j.1572-0241.2006.00943.x 17100967
-
Danese S Papa A Saibeni S Repici A Malesci A Vecchi M Inflammation and Coagulation in Inflammatory Bowel Disease: The Clot Thickens Am J Gastroenterol 2007, 102:174-186 10.1111/j.1572-0241.2006.00943.x 17100967
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 174-186
-
-
Danese, S.1
Papa, A.2
Saibeni, S.3
Repici, A.4
Malesci, A.5
Vecchi, M.6
|