Inflammatory bowel diseases are not associated with major hereditary conditions predisposing to thrombosis

Digestive Diseases and Sciences

Volumn 45, Issue 7, 2000, Pages 1465-1469

  Vecchi, M ^a   Sacchi, E ^a   Saibeni, S ^a   Meucci, G ^a   Tagliabue, L ^a   Duca, F ^a   De Franchis, R ^a  

^a FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

Author keywords

Crohn's disease; Factor V Leiden; Hyperhomocysteinemia; Inflammatory bowel diseases; Thrombosis; Ulcerative colitis

Indexed keywords

BLOOD CLOTTING FACTOR 5 LEIDEN; DNA; METHYLENETETRAHYDROFOLIC ACID; PROTHROMBIN;

ADULT; AGE DISTRIBUTION; ARTICLE; CONTROLLED STUDY; CROHN DISEASE; DISEASE ASSOCIATION; DNA DETERMINATION; DNA POLYMORPHISM; FEMALE; GENE MUTATION; GENETIC PREDISPOSITION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; SEX RATIO; THROMBOEMBOLISM; ULCERATIVE COLITIS;

ADULT; ALLELES; FACTOR V; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE; HOMOZYGOTE; HUMANS; INFLAMMATORY BOWEL DISEASES; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; MUTATION; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; PROTHROMBIN; REFERENCE VALUES; THROMBOSIS;

EID: 0033869354     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005541028045     Document Type: Article

References (30)

1. The course and prognosis of ulcerative colitis, part III: Complications
2. Extensive arterial and venous thrombosis complicating chronic ulcerative colitis
3. Vascular complications of inflammatory bowel disease
4. Venous thrombosis occurring in nonspecific ulcerative colitis: A necropsy study
5. Evidence for activation of coagulation in Crohn's disease
6. Pathogenesis of Crohn's disease: Multifocal gastrointestinal infarction
7. Is proximal demarcation of ulcerative colitis determined by the territory of the inferior mesenteric artery?
8. The factor V Leiden mutation increases the risk of venous thrombosis in patients with inflammatory bowel disease
9. Mutation in blood coagulation factor V associated with resistance to activated protein C
10. Activated protein C resistance (APCR) phenotype in patients with inflammatory bowel disease
11. Thrombophilia and inflammatory bowel disease: Does factor V mutation have a role?
12. Thrombosis in inflammatory bowel disease: Clinical setting, procoagulant profile and Factor V Leiden
13. Factor V Leiden mutation is not increased in patients with inflammatory bowel disease
14. Thromboembolism and resistance to activated protein C in patients with inflammatory bowel disease
15. Molecular genetic analysis in mild hyperhomocysteinemia: A common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease
16. A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma thrombin levels and an increase in venous thrombosis
17. A simple salting-out procedure for extracting DNA from human mutated cells
18. Laboratory diagnosis of APC-resistance: A critical evaluation of the test and the development of diagnostic criteria
19. A candidate genetic risk factor for vascular disease: A common mutation in methylene-tetrahydrofolate reductase
20. Thrombosis in inflammatory bowel disease
21. IBD: A vascular disorder? The case for heparin therapy
22. Inherited disorders of coagulation appear to protect against inflammatory bowel disease
23. Risk of thromboembolic complications in patients with inflammatory bowel disease: Study of haemostasis measurements
24. Prothrombotic state and signs of endothelial lesion in plasma of patients with inflammatory bowel disease
25. High prevalence of hyperhomocyst(e)inemia in patients with juvenile venous thrombosis
26. Homocysteine and vascular disease
27. Inflammatory bowel disease: Is it in the genes?
28. High prevalence of hyperhomocysteinemia in patients with inflammatory bowel disease: A pathogenic link with thromboembolic complications?
29. Resistence to activated protein C as a basis for venous thromboembolism associated with pregnancy and oral contraceptives
30. High frequency of the C677T mutation in the metylenetetrahydrofolate reductase (MTHFR) gene in mothern Italy