Establishment of a porcine right ventricular infarction model for cardioprotective actions of xenon and isoflurane

Acta Anaesthesiologica Scandinavica

Volumn 52, Issue 9, 2008, Pages 1194-1203

  Hein, M ^a   Roehl, A B ^a   Baumert, J H ^a   Bantes, B ^a   Bleilevens, C ^a   Bernstein, N ^a   Steendijk, P ^b   Rossaint, R ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; ISOFLURANE; MYELOPEROXIDASE; MYOGLOBIN; THIOPENTAL; TROPONIN T; TUMOR NECROSIS FACTOR ALPHA; XENON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE INJURY; HEART PROTECTION; HEART RIGHT VENTRICLE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; RIGHT CORONARY ARTERY; SWINE;

ANGIOGRAPHY; ANIMALS; BIOLOGICAL MARKERS; DISEASE MODELS, ANIMAL; HEART VENTRICLES; HEMODYNAMICS; ISOFLURANE; MYOCARDIAL INFARCTION; PEROXIDASE; RISK FACTORS; SUS SCROFA; SWINE; XENON;

EID: 51749123349     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/j.1399-6576.2008.01757.x     Document Type: Article

References (53)

1. Pfisterer M. Right ventricular involvement in myocardial infarction and cardiogenic shock. Lancet 2003 362 : 392 4.
2. Poldermans D, Schouten O, Vidakovic R, Bax JJ, Thomson IR, Hoeks SE, Feringa HHH, Dunkelgrun M, de Jaegere P, Maat A, van Sambeek MRHM, Kertai MD, Boersma E. A clinical randomized trial to evaluate the safety of a noninvasive approach in high-risk patients undergoing major vascular surgery: the DECREASE-V Pilot Study. J Am Coll Cardiol 2007 49 : 1763 9.
3. Kato R, Foex P. Myocardial protection by anesthetic agents against ischemia-reperfusion injury: an update for anesthesiologists. Can J Anaesth 2002 49 : 777 91.
4. Aagaard S, Larsen JR, Berg JS, Sloth E, Hasenkam JM. Does the pre-ischaemic administration of sevoflurane reduce myocardial stunning? A porcine experimental model. Acta Anaesthesiol Scand 2007 51 : 577 81.
5. De Hert SG, Van der Linden PJ, Cromheecke S, Meeus R, Nelis A, Van Reeth V, ten Broecke PW, De Blier IG, Stockman BA, Rodrigus IE. Cardioprotective properties of sevoflurane in patients undergoing coronary surgery with cardiopulmonary bypass are related to the modalities of its administration. Anesthesiology 2004 101 : 299 310.
6. Symons JA, Myles PS. Myocardial protection with volatile anaesthetic agents during coronary artery bypass surgery: a meta-analysis. Br J Anaesth 2006 97 : 127 36.
7. Cason BA, Gamperl AK, Slocum RE, Hickey RF. Anesthetic-induced preconditioning: previous administration of isoflurane decreases myocardial infarct size in rabbits. Anesthesiology 1997 87 : 1182 90.
8. Baumert J, Hein M, Gerets C, Baltus T, Hecker KE, Rossaint R. The effect of xenon anesthesia on the size of experimental myocardial infarction. Anesth Analg 2007 105 : 1200 6.
9. Kalenka A, Maurer MH, Feldmann RE, Kuschinsky W, Waschke KF. Volatile anesthetics evoke prolonged changes in the proteome of the left ventricule myocardium: defining a molecular basis of cardioprotection? Acta Anaesthesiol Scand 2006 50 : 414 27.
10. Weber NC, Toma O, Wolter JI, Obal D, Mullenheim J, Preckel B, Schlack W. The noble gas xenon induces pharmacological preconditioning in the rat heart in vivo via induction of PKC-epsilon and p38 MAPK. Br J Pharmacol 2005 144 : 123 32.
11. Wu ZK, Tarkka MR, Pehkonen E, Kaukinen L, Honkonen EL, Kaukinen S. Beneficial effects of ischemic preconditioning on right ventricular function after coronary artery bypass grafting. Ann Thorac Surg 2000 70 : 1551 7.
12. Mebazaa A, Karpati P, Renaud E, Algotsson L. Acute right ventricular failure - from pathophysiology to new treatments. Intensive Care Med 2004 30 : 185 96.
13. Heerdt PM, Gandhi CD, Dickstein ML. Disparity of isoflurane effects on left and right ventricular afterload and hydraulic power generation in swine. Anesth Analg 1998 87 : 511 21.
14. Kerbaul F, Rondelet B, Motte S, Fesler P, Hubloue I, Ewalenko P, Naeije R, Brimioulle S. Isoflurane and desflurane impair right ventricular-pulmonary arterial coupling in dogs. Anesthesiology 2004 101 : 1357 62.
15. Hettrick DA, Pagel PS, Kersten JR, Tessmer JP, Bosnjak ZJ, Georgieff M, Warltier DC. Cardiovascular effects of xenon in isoflurane-anesthetized dogs with dilated cardiomyopathy. Anesthesiology 1998 89 : 1166 73.
16. Baumert J, Falter F, Eletr D, Hecker KE, Reyle-Hahn M, Rossaint R. Xenon anaesthesia may preserve cardiovascular function in patients with heart failure. Acta Anaesthesiol Scand 2005 49 : 743 9.
17. Spalding MB, Ala-Kokko TI, Kiviluoma K, Alahuhta S, Juvonen T. Inhaled nitric oxide effectively decreases right heart afterload following right heart infarct in pigs. Scand Cardiovasc J 2001 35 : 45 9.
18. Nordhaug D, Steensrud T, Muller S, Husnes KV, Myrmel T. Intraaortic balloon pumping improves hemodynamics and right ventricular efficiency in acute ischemic right ventricular failure. Ann Thorac Surg 2004 78 : 1426 32.
19. Brookes C, Ravn H, White P, Moeldrup U, Oldershaw P, Redington A. Acute right ventricular dilatation in response to ischemia significantly impairs left ventricular systolic performance. Circulation 1999 100 : 761 7.
20. Laster SB, Ohnishi Y, Saffitz JE, Goldstein JA. Effects of reperfusion on ischemic right ventricular dysfunction. Disparate mechanisms of benefit related to duration of ischemia. Circulation 1994 90 : 1398 409.
21. Naslund U, Haggmark S, Johansson G, Marklund SL, Reiz S. A closed-chest myocardial occlusion-reperfusion model in the pig: techniques, morbidity and mortality. Eur Heart J 1992 13 : 1282 9.
22. Chiang BY, Ye CX, Gu YJ, Gao XD, Wang YS. Limitation of myocardial infarct size by a right ventricular assist device. ASAIO Trans 1990 36 : M398 401.
23. Johnston WE, Vinten-Johansen J, Shugart HE, Santamore WP. Positive end-expiratory pressure potentiates the severity of canine right ventricular ischemia-reperfusion injury. Am J Physiol 1992 262 : H168 76.
24. Fishbein MC, Meerbaum S, Rit J, Lando U, Kanmatsuse K, Mercier JC, Corday E, Ganz W. Early phase acute myocardial infarct size quantification: validation of the triphenyl tetrazolium chloride tissue enzyme staining technique. Am Heart J 1981 101 : 593 600.
25. Jordan JE, Zhao ZQ, Vinten-Johansen J. The role of neutrophils in myocardial ischemia-reperfusion injury. Cardiovasc Res 1999 43 : 860 78.
26. Frangogiannis NG, Smith CW, Entman ML. The inflammatory response in myocardial infarction. Cardiovasc Res 2002 53 : 31 47.
27. Skyschally A, Gres P, Hoffmann S, Haude M, Erbel R, Schulz R, Heusch G. Bidirectional role of tumor necrosis factor-alpha in coronary microembolization: progressive contractile dysfunction versus delayed protection against infarction. Circ Res 2007 100 : 140 6.
28. Fishbein MC, Wang T, Matijasevic M, Hong L, Apple FS. Myocardial tissue troponins T and I. An immunohistochemical study in experimental models of myocardial ischemia. Cardiovasc Pathol 2003 12 : 65 71.
29. Gibbons RJ, Valeti US, Araoz PA, Jaffe AS. The quantification of infarct size. J Am Coll Cardiol 2004 44 : 1533 42.
30. Guide for the care and use of laboratory animals. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, 7th edn. Washington DC : National Academy Press, 1996.
31. de Lorgeril M, Basmadjian A, Clement R, Rousseau G, Latour JG. Influence of reflow ventricular fibrillation and electrical defibrillation on infarct size in a canine preparation of myocardial infarction. Cardiovasc Res 1990 24 : 151 5.
32. Schmidt M, Marx T, Kotzerke J, Luderwald S, Armbruster S, Topalidis P, Schirmer U, Reinelt H. Cerebral and regional organ perfusion in pigs during xenon anaesthesia. Anaesthesia 2001 56 : 1154 9.
33. Marx T, Froeba G, Wagner D, Baeder S, Goertz A, Georgieff M. Effects on haemodynamics and catecholamine release of xenon anaesthesia compared with total i.v. anaesthesia in the pig. Br J Anaesth 1997 78 : 326 7.
34. Mullane KM, Kraemer R, Smith B. Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium. J Pharmacol Met 1985 14 : 157 67.
35. Saleh S, Liakopoulos OJ, Buckberg GD. The septal motor of biventricular function. Eur J Cardiothorac Surg 2006 29 (Suppl. 1) : S126 38.
36. Wouters PF, Van Aken H, Marcus MA, Van De Velde M, Van Herck A, Flameng W. Effects of halothane and isoflurane on collateral dependent myocardium in chronically instrumented dogs. Anesth Analg 1993 77 : 516 25.
37. Larsen JR, Aagaard SR, Hasenkam JM, Sloth E. Pre-occlusion ischaemia, not sevoflurane, successfully preconditions the myocardium against further damage in porcine in vivo hearts. Acta Anaesthesiol Scand 2007 51 : 402 9.
38. Piriou V, Chiari P, Lhuillier F, Bastien O, Loufoua J, Raisky O, David JS, Ovize M, Lehot JJ. Pharmacological preconditioning: comparison of desflurane, sevoflurane, isoflurane and halothane in rabbit myocardium. Br J Anaesth 2002 89 : 486 91.
39. Preckel B, Mullenheim J, Moloschavij A, Thamer V, Schlack W. Xenon administration during early reperfusion reduces infarct size after regional ischemia in the rabbit heart in vivo. Anesth Analg 2000 91 : 1327 32.
40. Kitagawa H, Yamazaki T, Akiyama T, Nosaka S, Mori H. Isoflurane attenuates myoglobin release during ischemic and/or reperfusion periods. Acta Anaesthesiol Scand 2008 52 : 650 7.
41. O'Brien PJ, Dameron GW, Beck ML, Kang YJ, Erickson BK, Di Battista TH, Miller KE, Jackson KN, Mittelstadt S. Cardiac troponin T is a sensitive, specific biomarker of cardiac injury in laboratory animals. Lab Anim Sci 1997 47 : 486 95.
42. Du Toit EF, Muller CA, McCarthy J, Opie LH. Levosimendan: effects of a calcium sensitizer on function and arrhythmias and cyclic nucleotide levels during ischemia/reperfusion in the Langendorff-perfused guinea pig heart. J Pharmacol Exp Ther 1999 290 : 505 14.
43. Zhao Z, Vinten-Johansen J. Postconditioning: reduction of reperfusion-induced injury. Cardiovasc Res 2006 70 : 200 11.
44. Galie N, Guarnieri C, Ussia GP, Zimarino M, Traini AM, Parlangeli R, Vaona I, Branzi A, Magnani B. Limitation of myocardial infarct size by nicorandil after sustained ischemia in pigs. J Cardiovasc Pharmacol 1995 26 : 477 84.
45. Weber NC, Kandler J, Schlack W, Grueber Y, Fradorf J, Preckel B. Intermitted pharmacologic pretreatment by xenon, isoflurane, nitrous oxide, and the opioid morphine prevents tumor necrosis factor alpha-induced adhesion molecule expression in human umbilical vein endothelial cells. Anesthesiology 2008 108 : 199 207.
46. Litt MR, Jeremy RW, Weisman HF, Winkelstein JA, Becker LC. Neutrophil depletion limited to reperfusion reduces myocardial infarct size after 90 minutes of ischemia. Evidence for neutrophil-mediated reperfusion injury. Circulation 1989 80 : 1816 27.
47. Jacobs M, Staufenberger S, Gergs U, Meuter K, Brandstatter K, Hafner M, Ertl G, Schorb W. Tumor necrosis factor-alpha at acute myocardial infarction in rats and effects on cardiac fibroblasts. J Mol Cell Cardiol 1999 31 : 1949 59.
48. Dai R, Xu J, Tao L, Li L, Li Z, Zhang J. Induction of tumor necrosis-alpha, p38 and JNK in the spinal cord following acute heart injury in the rat model. Acta Anaesthesiol Scand 2007 51 : 365 71.
49. Liu X, Shen J, Jin Y, Duan M, Xu J. Recombinant human erythropoietin (rhEPO) preconditioning on nuclear factor-kappa B (NF-κB) activation proinflammatory cytokines induced by myocardial ischaemia-reperfusion. Indian J Med Res 2006 124 (3) : 343 54.
50. Shafer SL, Stanski DR. Defining depth of anesthesia. Handbook Exp Pharmacol 2008 409 23.
51. Karlson JA, Hopkins RW, Moran JM, Karlson KE. Long-term amiodarone administration protects against global myocardial ischemia. Ann Thorac Surg 1990 50 : 575 8.
52. Herzog WR, Schlossberg ML, MacMurdy KS, Edenbaum LR, Gerber MJ, Vogel RA, Serebruany VL. Timing of magnesium therapy affects experimental infarct size. Circulation 1995 92 : 2622 6.
53. Mullenheim J, Molojavyi A, Preckel B, Thamer V, Schlack W. Thiopentone does not block ischemic preconditioning in the isolated rat heart. Can J Anaesth 2001 48 : 784 9.