Epidermal growth factor in neonatal saliva

European Journal of Pediatric Surgery

Volumn 18, Issue 4, 2008, Pages 245-248

  Gupta, Amit ^a   Lakhoo, K ^a   Pritchard, N ^a   Herbert, M ^a  

^a Children's Hospital   (United Kingdom)

Author keywords

Epidermal growth factor; Necrotising enterocolitis; Newborn

Indexed keywords

EPIDERMAL GROWTH FACTOR;

ARTICLE; BIRTH WEIGHT; BREAST FEEDING; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE MARKER; ENTERIC FEEDING; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GESTATIONAL AGE; HUMAN; INFANT; MALE; NECROTIZING ENTEROCOLITIS; NORMAL HUMAN; PROTEIN ANALYSIS; SALIVA ANALYSIS; SALIVA LEVEL;

EPIDERMAL GROWTH FACTOR; FEMALE; GESTATIONAL AGE; HUMANS; MALE; PROSPECTIVE STUDIES; SALIVA;

EID: 51749105400     PISSN: 09397248     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1038392     Document Type: Article

References (21)

1. Dvorak B, Fituch CC, Williams CS, Hurst NM, Schanler RJ. Increased epidermal growth factor levels in human milk of mothers with extremely premature infants. Pediatr Res 2003; 54: 15-19
2. Dvorak B, Halpern MD, Holubec H, Dvorakova K, Dominguez JA, Williams CS et al. Maternal milk reduces severity of necrotizing enterocolitis and increases intestinal IL-10 in a neonatal rat model. Pediatr Res 2003; 53: 426-433
3. Dvorak B, Halpern MD, Holubec H, Williams CS, McWilliam DL, Dominguez JA et al. Epidermal growth factor reduces the development of necrotizing enterocolitis in a neonatal rat model. Am J Physiol Gastrointest Liver Physiol 2002; 282: G156-G164
4. Goodlad RA, Wilson TJ, Lenton W, Gregory H, McCullagh KG, Wright NA. Proliferative effects of urogastrone-EGF on intestinal epithelium. Gut 1987; 28 (Suppl): 37-43
5. Helmrath MA, Shin CE, Fox JW, Erwin CR, Warner BW. Epidermal growth factor in saliva and serum of infants with necrotising enterocolitis. Lancet 1998; 351: 266-267
6. Holman RC, Stoll BJ, Clarke MJ, Glass RI. The epidemiology of necrotizing enterocolitis infant mortality in the United States. Am J Public Health 1997; 87: 2026-2031
7. Kaufman E, Lamster IB. The diagnostic applications of saliva - a review. Crit Rev Oral Biol Med 2002; 13: 197-212
8. Miettinen PJ, Berger JE, Meneses J, Phung Y, Pedersen RA, Werb Z et al. Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor. Nature 1995; 376: 337-341
9. Olsen PS, Paulsen SS, Kirkegaard P, Nexo E. Role of submandibular saliva and epidermal growth factor in gastric cytoprotection. Gastroenterology 1984: 87: 103-108
10. Playford RJ, Hanby AM, Gschmeissner S, Peiffer LP, Wright NA, McGarrity T. The epidermal growth factor receptor (EGF-R) is present on the basolateral, but not the apical, surface of enterocytes in the human gastrointestinal tract. Gut 1996; 39: 262-266
11. Rao RK, Thomas DW, Pepperl S, Porreca F. Salivary epidermal growth factor plays a role in protection of ileal mucosal integrity. Dig Dis Sci 1997; 42: 2175-2181
12. Scott SM, Guardian CM, Angelus P, Backstrom C. Developmental pattern of urinary epidermal growth factor in the premature infant and the influence of gender. J Clin Endocrinol Metab 1991; 72: 588-593
13. Scott SM, Rogers C, Angelus P, Backstrom C. Effect of necrotizing enterocolitis on urinary epidermal growth factor levels. Am J Dis Child 1991; 145: 804-807
14. Shin CE, Falcone RA Jr, Stuart L, Erwin CR, Warner BW. Diminished epidermal growth factor levels in infants with necrotizing enterocolitis. J Pediatr Surg 2000; 35: 173-176
15. Streckfus CF, Bigler LR. Saliva as a diagnostic fluid. Oral Dis 2002; 8: 69-76
16. Sullivan PB, Brueton MJ, Tabara ZB, Goodlad RA, Lee CY, Wright NA. Epidermal growth factor in necrotising enteritis. Lancet 1991; 338: 53-54
17. Walker-Smith JA, Phillips AD, Walford N, Gregory H, Fitzgerald JD, MacCullagh K et al. Intravenous epidermal growth factor/urogastrone increases small-intestinal cell proliferation in congenital microvillous atrophy. Lancet 1985; 2: 1239-1240
18. Warner BB, Ryan AL, Seeger K, Leonard AC, Erwin CR, Warner BW. Ontogeny of salivary epidermal growth factor and necrotizing enterocolitis. J Pediatr 2007; 150: 358-363
19. Warner BW. NEC, EGF, milk, and spit. Gastroenterology 2002; 123: 383-384
20. Warner BW, Warner BB. Role of epidermal growth factor in the pathogenesis of neonatal necrotizing enterocolitis. Semin Pediatr Surg 2005; 14: 175-180
21. Wong DT. Towards a simple, saliva-based test for the detection of oral cancer 'oral fluid (saliva), which is the mirror of the body, is a perfect medium to be explored for health and disease surveillance'. Expert Rev Mol Diagn 2006; 6: 267-272