메뉴 건너뛰기




Volumn 660, Issue , 2004, Pages 615-620

A model system to study the structural stability of engineered antibodies: Mutants of a SCFV specific to AMCV

Author keywords

Antibody structure stability; Engineered antibody; Site directed mutagenesis

Indexed keywords


EID: 51749085444     PISSN: 05677572     EISSN: None     Source Type: Book Series    
DOI: 10.17660/ActaHortic.2004.660.94     Document Type: Conference Paper
Times cited : (1)

References (16)
  • 1
    • 0031558798 scopus 로고    scopus 로고
    • Standard conformations for the canonical structures of immunoglobulins
    • Al-Lazikani, B., Chothia, C. and Lesk, A.M. 1997. Standard conformations for the canonical structures of immunoglobulins. J.Mol.Biol 273(4): 927.
    • (1997) J.Mol.Biol , vol.273 , Issue.4 , pp. 927
    • Al-Lazikani, B.1    Chothia, C.2    Lesk, A.M.3
  • 2
    • 0023173201 scopus 로고
    • Prediction of the folding of short polypeptide segments by uniform conformational sampling
    • Bruccoleri, RE and Karplus, M. 1987. Prediction of the folding of short polypeptide segments by uniform conformational sampling. Biopolymers 26: 137.
    • (1987) Biopolymers , vol.26 , pp. 137
    • Bruccoleri, R.E.1    Karplus, M.2
  • 3
    • 0026580511 scopus 로고
    • Developmentally controlled selection of antibody genes: Characterization of individual VH7183 genes and evidences for stage-specific somatic diversification
    • Carlsson, L., Overmo, C. and Holmberg, D. 1992. Developmentally controlled selection of antibody genes: Characterization of individual VH7183 genes and evidences for stage-specific somatic diversification. Eur. J.Immunol. 22(1): 71-78.
    • (1992) Eur. J.Immunol. , vol.22 , Issue.1 , pp. 71-78
    • Carlsson, L.1    Overmo, C.2    Holmberg, D.3
  • 4
    • 0028234926 scopus 로고
    • Sequences of four new members of the Vh7183 gene family in BALB/c mice
    • Chukwuocha, R.U., Hartman, A.B. and Feeney, A.J. 1994. Sequences of four new members of the Vh7183 gene family in BALB/c mice. Immunogenetics 40: 76-78.
    • (1994) Immunogenetics , vol.40 , pp. 76-78
    • Chukwuocha, R.U.1    Hartman, A.B.2    Feeney, A.J.3
  • 6
    • 0000243829 scopus 로고
    • PROCHECK: A program to check the stereochemical quality of protein structures
    • Laskowski, R.A., MacArthur, M.W., Moss, D.S. and Thornton, J.M. 1993. PROCHECK: a program to check the stereochemical quality of protein structures. J. Appl. Crystallog. 26, 283-291.
    • (1993) J. Appl. Crystallog. , vol.26 , pp. 283-291
    • Laskowski, R.A.1    Macarthur, M.W.2    Moss, D.S.3    Thornton, J.M.4
  • 8
    • 0028966985 scopus 로고
    • Engineered turns of a recombinant antibody improve its in vivo folding
    • Knappik, A. and Plückthun, A. 1995. Engineered turns of a recombinant antibody improve its in vivo folding. Protein Engineering 8: 81-89.
    • (1995) Protein Engineering , vol.8 , pp. 81-89
    • Knappik, A.1    Plückthun, A.2
  • 11
    • 0028111743 scopus 로고
    • Sequence statistics reliably predict stabilizing mutations in a protein domain
    • Steipe, B., Schiller, B., Plückthun, A. and Steinbacher, S. 1994. Sequence statistics reliably predict stabilizing mutations in a protein domain. J. Mol. Biol. 240: 188-192.
    • (1994) J. Mol. Biol. , vol.240 , pp. 188-192
    • Steipe, B.1    Schiller, B.2    Plückthun, A.3    Steinbacher, S.4
  • 12
    • 0027742234 scopus 로고
    • Transgenic plants expressing a functional "single chain Fv antibody" are specifically protected from virus attack
    • Tavladoraki, P., Benvenuto, E., Trinca, S., De Martinis, D., Cattaneo, A. and Galeffi, P. 1993. Transgenic plants expressing a functional "single chain Fv antibody" are specifically protected from virus attack. Nature 366: 469-472.
    • (1993) Nature , vol.366 , pp. 469-472
    • Tavladoraki, P.1    Benvenuto, E.2    Trinca, S.3    De Martinis, D.4    Cattaneo, A.5    Galeffi, P.6
  • 13
    • 0033695071 scopus 로고    scopus 로고
    • Fully "recombinant enzyme-linked immunosorbent assays" using genetically engineered single-chain antibody fusion proteins for detection of Citrus tristeza virus
    • Terrada, E., Kerschvaumer, R.J., Giunta, G., Galeffi, P., Himmler, G. and Cambra, M. 2000. Fully "recombinant enzyme-linked immunosorbent assays" using genetically engineered single-chain antibody fusion proteins for detection of Citrus tristeza virus. Phytopathology 90: 1337-1344.
    • (2000) Phytopathology , vol.90 , pp. 1337-1344
    • Terrada, E.1    Kerschvaumer, R.J.2    Giunta, G.3    Galeffi, P.4    Himmler, G.5    Cambra, M.6
  • 15
    • 0025398721 scopus 로고
    • WHAT IF: A molecular modeling and drug design program
    • Vriend G.1990. WHAT IF: A molecular modeling and drug design program. J. Mol. Graph. 8: 52-56.
    • (1990) J. Mol. Graph. , vol.8 , pp. 52-56
    • Vriend, G.1
  • 16
    • 0034458999 scopus 로고    scopus 로고
    • WAM-an improved algorithm for modelling antibodies on the Web
    • Whitelegg, N.R.J. and Rees, A.R. 2000. WAM-an improved algorithm for modelling antibodies on the Web. Prot. Eng. 13: 819-824. Ricerca Scientifica
    • (2000) Prot. Eng. , vol.13 , pp. 819-824
    • Whitelegg, N.R.J.1    Rees, A.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.