Acquisition of BRAF gene mutations is not a requirement for nodal metastasis of papillary thyroid carcinoma

Clinical Endocrinology

Volumn 69, Issue 4, 2008, Pages 683-685

  Trovisco, Vítor ^a   Couto, Joana Pinto ^a   Cameselle Teijeiro, José ^b   De Castro, Inês Vieira ^c   Fonseca, Elsa ^d,e   Soares, Paula ^a,d   Sobrinho Simões, Manuel ^a,d,e  

^a UNIVERSITY OF PORTO   (Portugal)

^b Instituto de Salud Carlos III   (Spain)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d University of Porto   (Portugal)

^e HOSPITAL DE SÃO JOÃO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE;

BRAF GENE; CANCER GROWTH; CLINICAL ARTICLE; GENE; GENE MUTATION; HUMAN; HUMAN TISSUE; LETTER; LYMPH NODE METASTASIS; MOLECULAR CLONING; MUTATION RATE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; THYROID PAPILLARY CARCINOMA;

EID: 51649128260     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2008.03243.x     Document Type: Letter

References (6)

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2. Vasko, V., Hu, S., Wu, G., Xing, J.C., Larin, A., Savchenko, V., Trink, B Xing, M 2005) High prevalence and possible de novo formation of BRAF mutation in metastasized papillary thyroid cancer in lymph nodes. Journal of Clinical Endocrinology and Metabolism, 90, 5265 5269.
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4. Trovisco, V., Soares, P., Soares, R., Magalhaes, J., Sa-Couto, P. Sobrinho-Simoes, M. (2005) A new BRAF gene mutation detected in a case of a solid variant of papillary thyroid carcinoma. Human Pathology, 36, 694 697.
5. Soares, P., Trovisco, V., Rocha, A.S., Lima, J., Castro, P., Preto, A., Máximo, V., Botelho, T., Seruca, R. Sobrinho-Simões, M. (2003) BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC. Oncogene, 22, 4578 4580.
6. Trovisco, V., Vieira, D.C.I., Soares, P., Maximo, V., Silva, P., Magalhaes, J., Abrosimov, A., Guiu, X.M. Sobrinho-Simões, M. (2004) BRAF mutations are associated with some histological types of papillary thyroid carcinoma. Journal of Pathology, 202, 247 251.