Comparison of daily, weekly, and monthly vitamin D3 in ethanol dosing protocols for two months in elderly hip fracture patients

Journal of Clinical Endocrinology and Metabolism

Volumn 93, Issue 9, 2008, Pages 3430-3435

  Ish Shalom, Sophia ^a,b,e   Segal, Elena ^a   Salganik, Tina ^a   Raz, Batia ^a   Bromberg, Irvin L ^c,d   Vieth, Reinhold ^c,d  

^a Metabolic Bone Diseases Unit   (Israel)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^c UNIVERSITY OF TORONTO   (Canada)

^d MOUNT SINAI HOSPITAL   (Canada)

^e RAMBAM MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; ALCOHOL; CALCITRIOL; CALCIUM; COLECALCIFEROL; VITAMIN D;

AGED; ARTICLE; CONTROLLED STUDY; FEMALE; HIP FRACTURE; HIP SURGERY; HUMAN; PRIORITY JOURNAL; TREATMENT DURATION; VITAMIN SUPPLEMENTATION;

EID: 51649125765     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2008-0241     Document Type: Article

References (27)

1. Cummings SR, Melton LJ 2002 Epidemiology and outcomes of osteoporotic fractures. Lancet 359:1761-1767
2. Bischoff-Ferrari HA, Willett WC, Wong JB, Giovannucci E, Dietrich T, Dawson-Hughes B 2005 Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. JAMA 293:2257-2264
3. Segal E, Zinnman H, Raz B, Tamir A, Ish-Shalom S 2004 Adherence to vitamin D supplementation in elderly patients after hip fracture. J Am Geriatr Soc 52:474-475
4. Kruk ME, Schwalbe N 2006 The relation between intermittent dosing and adherence: preliminary insights. Clin Ther 28:1989-1995
5. Rossini M, Viapiana O, Idolazzi L, Fracassi E, Gatti D, Adami S 2007 [Rational and results of weekly treatment with calcidiol in postmenopausal and senile osteoporosis]. Minerva Med 98:53-68 (Italian)
6. Vieth R 2005 The pharmacology of vitamin D, including fortification strategies. In: Feldman D, Glorieux F, Pike JW, eds. Vitamin D. New York: Elsevier; 995-1015
7. Ilahi M, Armas LA, Heaney RP 2008 Pharmacokinetics of a single, large dose of cholecalciferol. Am J Clin Nutr 87:688-691
8. Koster JC, Hackeng WH, Mulder H 1996 Diminished effect of etidronate in vitamin D deficient osteopenic postmenopausal women. Eur J Clin Pharmacol 51:145-147
9. Dawson-Hughes B, Heaney RP, Holick MF, Lips P, Meunier PJ, Vieth R 2005 Estimates of optimal vitamin D status. Osteoporos Int 16:713-716
10. Vieth R, McCarten K, Norwich KH 1990 Role of 25-hydroxyvitamin D3 dose in determining rat 1,25-dihydroxyvitamin D3 production. Am J Physiol 258(5 Pt 1):E780-E789
11. Trang H, Cole DE, Rubin LA, Pierratos A, Siu S, Vieth R 1998 Evidence that vitamin D3 increases serum 25-hydroxyvitamin D more efficiently than does vitamin D2. Am J Clin Nutr 68:854-848
12. Vieth R, Chan PC, MacFarlane GD 2001 Efficacy and safety of vitamin D(3) intake exceeding the lowest observed adverse effect level. Am J Clin Nutr 73:288-294
13. Kimball SM, Ursell MR, O'Connor P, Vieth R 2007 Safety of vitamin D3 in adults with multiple sclerosis. Am J Clin Nutr 86:645-651
14. Aickin M, Gensler H 1996 Adjusting for multiple testing when reporting research results: the Bonferroni vs Holm methods. Am J Public Health 86:726-728
15. Vieth R 1999 Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety. Am J Clin Nutr 69:842-856
16. Chel V, Wijnhoven HA, Smit JH, Ooms M, Lips P 2008 Efficacy of different doses and time intervals of oral vitamin D supplementation with or without calcium in elderly nursing home residents. Osteoporos Int 19:663-671
17. Trivedi DP, Doll R, Khaw KT 2003 Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial. BMJ 326:469
18. Buxton ILO 2006 Pharmacokinetics and pharmacodynamics: the dynamics of drug absorption, distribution, action, and elimination. In: Brunton LL, ed. Goodman & Gilman's the pharmacological basis of therapeutics. 11th ed. New York: McGraw-Hill Medical Publishing Division; 1-41
19. Vieth R, Milojevic S 1995 Moderate vitamin D3 supplementation lowers serum 1,25-dihydroxy-vitamin D3 in rats. Nutr Res 15:725-731
20. Wagner D, Sidhom G, Whiting SJ, Rousseau D, Vieth R Equivalent bioavailability of vitamin D from fortified cheeses and supplement. J Nutr, in press
21. Schoenfeld DA 2008 Statistical considerations for clinical trials and scientific experiments. http://hedwig.mgh.harvard.edu/sample_size/size.html Accessed March 21, 2008
22. Vieth R, Kimball S, Hu A, Walfish PG 2004 Randomized comparison of the effects of the vitamin D3 adequate intake versus 100 mcg (4000 IU) per day on biochemical responses and the wellbeing of patients. Nutr J 3:8
23. Heaney RP 2007 Vitamin D endocrine physiology. J Bone Miner Res 22(Suppl 2):V25-V27
24. Vieth R 2007 Vitamin D toxicity: policy and science. J Bone Miner Res 22(Suppl 2):V64-V68
25. Heaney RP 2005 The vitamin D requirement in health and disease. J Steroid Biochem Mol Biol 97:13-19
26. Visser M, Deeg DJ, Puts MT, Seidell JC, Lips P 2006 Low serum concentrations of 25-hydroxyvitamin D in older persons and the risk of nursing home admission. Am J Clin Nutr 84:616-622
27. Autier P, Gandini S 2007 Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. Arch Intern Med 167:1730-1737