Expandable intramedullary nailing and platelet rich plasma to treat long bone non-unions

Journal of Orthopaedics and Traumatology

Volumn 9, Issue 3, 2008, Pages 129-134

  Galasso, Olimpio ^a   Mariconda, Massimo ^a,b   Romano, Gaetano ^a,c   Capuano, Nicola ^a,d   Romano, Luigi ^a,c   Iannò, Bruno ^a   Milano, Carlo ^a,b  

^a UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c CARDARELLI HOSPITAL   (Italy)

^d Ospedale San Luca   (Italy)

Author keywords

Intramedullary nailing; Platelet rich plasma; Pseudoarthrosis

Indexed keywords

ADULT; ARTICLE; CELL THERAPY; CLINICAL ARTICLE; DECORTICATION; DEVICE REMOVAL; FEMALE; FRACTURE FIXATION; FRACTURE HEALING; FRACTURE NONUNION; HUMAN; INTRAMEDULLARY NAILING; LONG BONE; MALE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PSEUDARTHROSIS; THROMBOCYTE RICH PLASMA; TREATMENT RESPONSE;

EID: 51649125642     PISSN: 15909921     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10195-008-0021-7     Document Type: Article

References (27)

1. Rodriguez-Merchan EC (2004) Editorial comment. Clin Orthop Relat Res 419:1
2. Lemaire R (2000) Management of non-unions. An overview. In: Duparc J (ed) Surgical techniques in orthopaedics and traumatology. EFORT 1. Elsevier, Paris 55-030-F-10
3. Rosen H (1998) Non-union and Malunion. In: Browner BD, Jupiter JB, Levine AM, Trafton PG (eds) Skeletal Trauma, vol 1, 2nd edn. WB Saunders, Philadelphia, pp 619-660
4. Schmitt JM, Hwang K, Winn SR, Hollinger JO (1999) Bone morphogenetic proteins: An update on basic biology and clinical relevance. J Orthop Res 17:269-278
5. Lamerigts NM, Buma P, Aspenberg P, Schreurs BW, Slooff TJ (1999) Role of growth factors in the incorporation of unloaded bone allografts in the goat. Clin Orthop Relat Res 368:260-270
6. Bostrom MP, Asnis P (1998) Transforming growth factor beta in fracture repair. Clin Orthop Relat Res 355S:124-131
7. Peng H, Usas A, Olshanski A, Ho AM, Gearhart B, Cooper GM, Huard J (2005) VEGF improves, whereas sFlt1 inhibits, BMP2-induced bone formation and bone healing through modulation of angiogenesis. J Bone Miner Res 20:2017-2027
8. Geiger F, Bertram H, Berger I, Lorenz H, Wall O, Eckhardt C, Simank HG, Richter W (2005) Vascular endothelial growth factor gene-activated matrix (VEGF165-GAM) enhances osteogenesis and angiogenesis in large segmental bone defects. J Bone Miner Res 20:2028-2035
9. Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR (1998) Platelet rich plasma: Growth factor enhancement for bone grafts. Oral Surg 85:638-646
10. Bhandari M, Guyatt GH, Swiontkowski MF, Tornetta P, Sprague S, Schemitsch EH (2002) A lack of consensus in the assessment of fracture healing among orthopaedic surgeons. Orthop Trauma 16:562-566
11. Eppley BL, Woodell JE, Higgins J (2004) Platelet quantification and growth factor analysis from platelet-rich plasma: Implications for wound healing. Plast Reconstr Surg 114:1502-1508
12. Gaffney PJ, Edgell TA (1998) The second British Standard for Batroxobin (moojeni). Tromb Haemost 80:1037-1038
13. Daccarett M, Walz BM, Seligson D (2004) Use of an expanadable nail in the treatment of non-union fractures of the femur, tibia, and humerus. Osteo Trauma Care 12:130-134
14. Ahlo A, Ekeland A, Stromsoe K (1993) Non-union of tibial shaft fractures treated with locked intramedullary nailing without bone grafting. J Trauma 34:62-67
15. Moed BR, Watson JT (1995) Intramedullary nailing of aseptic tibial non-unions without the use of the fracture table. J Orthop Trauma 9:128-134
16. Pihlajamaki HK, Salminen ST, Bostman OM (2002) The treatment of non-unions using intramedullary nailing of femoral shaft fractures. J Orthop Trauma 16:394-402
17. Kempf I, Grosse A, Rigault P (1986) The treatment of non-infected pseudoarthrosis of the femur and tibia with locked intramedullary nailing. Clin Orthop Relat Res 212:142-154
18. Blum J, Janzing H, Gahr R (2001) Clinical performance of a new medullar nail. J Orthopaed Traumatol 342-349
19. Lepore S, Capuano N, Romano G (2000) Preliminary clinical and radiographic results with the Fixion Intramedullary Nail: An inflatable self-locking system for long bone fracture. J Orthopaed Traumatol 3:135-140
20. Franck WM, Olivieri M, Jannasch O, Hennig FF (2002) An expandable nailing system for the management of pathological humerus fractures. Arch Orthop Trauma Surg 122:400-405
21. Court-Brown CM, McQueen MM, Quaba AA, Christie J (1991) Locked intramedullary nailing of open tibial fractures. J Bone Joint Surg 73B:959-964
22. Heim D, Regazzoni P, Tsakiris DA, Aebi T, Schlegel U, Marbet GA, Perren SM (1995) Intramedullary nailing and pulmonary embolism: Does unreamed nailing prevent embolization? An in vitro study in rabbit. J Trauma 38:899-906
23. Bonatus T, Olson SA, Lee S, Chapmann MW (1997) Non reamed locking intramedullary nailing for open fractures of the tibia. Clin Orthop Relat Res 339:58-64
24. Koval KJ, Clapper MF, Brumback RJ, Ellison PS Jr, Poka A, Bathon GH, Burgess AR (1991) Complications of reamed intramedullary nailing of the tibia. J Orthop Trauma 5:184-189
25. Klein MP, Rahn BA, Frigg R, Kessler S, Perren SM (1990) Reaming versus non-reaming in medullary nailing: Interference with cortical circulation of the canine tibia. Arch Ortop Trauma Surg 109:314-316
26. Schemitsch EH, Kowalski MJ, Swiontkowski MF, Senft D (1994) Cortical bone blood flow in reamed and unreamed locked intra medullary nailing: A fractured tibia model in sheep. J Orthop Trauma 8:373-382
27. Grundnes O, Reikeras O (1993) Acute effects of intramedullary reaming on bone blood flow in rats. Acta Orthop Scan 64:203-206