Optimization of production of PLA microbubble ultrasound contrast agents for Hydroxycamptothecin delivery

BioMedical Engineering and Informatics: New Development and the Future - Proceedings of the 1st International Conference on BioMedical Engineering and Informatics, BMEI 2008

Volumn 1, Issue , 2008, Pages 400-406

  Pan, Jie ^a   Hou, Zhenqing ^a   Zhu, Peijuan ^a   Wang, Yange ^a   Wang, Qian ^a   Zhang, Qiqing ^a  

^a XIAMEN UNIVERSITY   (China)

Author keywords

Drug delivery; Hydroxycamptothecin (HCPT); Poly lactic acid (PLA); Ultrasound contrast agent

Indexed keywords

DRUG DELIVERY; HYDROXYCAMPTOTHECIN (HCPT); MICRO-BUBBLES; POLY LACTIC ACID (PLA); ULTRASOUND CONTRAST AGENT;

ABS RESINS; ACIDS; ACOUSTIC WAVES; AGENTS; BIOMEDICAL ENGINEERING; BIOPHYSICS; CONCENTRATION (PROCESS); DRUG PRODUCTS; EMULSIFICATION; LACTIC ACID; LEAKAGE (FLUID); MEDICAL IMAGING; OIL WELL PRODUCTION; OPTIMIZATION; ORGANIC ACIDS; POLYMERIC GLASS; THEOREM PROVING; ULTRASONIC TRANSMISSION; ULTRASONICS;

ULTRASONIC IMAGING;

EID: 51549121787     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/BMEI.2008.340     Document Type: Conference Paper

References (19)

1. R. Gramiak, P.M. Shah. "Echocardiography of the aortic root dissection", The American Journal of Cardiology, 1973, pp. 150.
2. Barry B. Goldberg, Ji-Bin Liu and Flemming Forsberg, "Ultrasound contrast agents: a review", Ultrasound in Medicine & Biology, 1994, pp. 319-333.
3. Wheatley MA, Narayan P, "Diagnostic use of microspheres", Encyclopedia of controlled drug delivery, New York Wiley, 1999, pp. 313-340.
4. Kitzman DW, Goldman ME, Gillam LD, Cohen JL, Aurigemma GP, Gottdiener JS, "Efficacy and safety of the novel ultrasound contrast agent perflutren (definity) in patients with suboptimal baseline left ventricular echocardiographic images", Am J Cardiol, 2000, pp. 669-674.
5. Flemming Forsberg, Yunqui Wu, Inder R.S. Makin, Wenhua Wang and Margaret A. Wheatley "Quantitative acoustic characterization of a new surfactant-based ultrasound contrast agent", Ultrasound in Medicine & Biology, 1997, pp. 1201-1208.
6. Reed AM, Gilding DK, "Biodegradable polymers for use in surgery-poly (glycolic)/polymer (lactic acid) homo and copolymers", In vitro degradation. Polymer 1981, pp. 494-498.
7. Yamaguchi K, Anderson JM, "In vivo biocompatibility studies of Medisorb 65/35 D, L-lactide/glycolide copolymer microspheres", J. Control. Release, pp. 1993;24:81-93.
8. Gopferich A, "Mechanics of polymer degradation and erosion", Biomaterials 1996, pp. 103-114.
9. Pistner H, Bendix DR, Muhling J, Reuther JF, "Poly (L-Lactide):a long-term degradation study in vivo", Biomaterials, 1993;pp. 291-298.
10. Sakyba DM, Price RJ, Linka AZ, et al, "Direct in vivo visualization of intravascular destruction of microbubbles by ultrasound and its effects on tissue", Circulation, 1998, pp. 290-193.
11. Jonathan R. Linder, "Targeted ultrasound contrast agents: diagnostic and therapeutic potential", IEEE Ultrasonics symposium, 2001, pp. 1695-1703.
12. Zhong-Gao Gao, Heidi D. Fain and Natalya Rapoport, "Controlled and targeted tumor chemotherapy by micellar-encapsulated drug and ultrasound", Journal of Controlled Release, 2005, pp. 203-222.
13. Jain RA, "The manufacturing techniques of various drug loaded biodegradable poly (lactide-co-glycolide) (PLGA) devices", Biomaterials, 2000, pp. 2475-2490.
14. Dalia M. El-Sherif, Margaret A. Wheatley, "Development of a novel method for synthesis of a polymeric ultrasound contrast agent", J Biomed Material, Wiley Periodicals, Inc., 2003, pp. 347-355.
15. Brophy RM, "Biodegradable polyester polymers as drug carriers", Encyclopedia of pharmaceutical technology, New York Marcel Dekker, 1990, pp. 1-25.
16. Wu XS. "Synthesis and properties of biodegradable lactic/glycolic acid polymers", Encyclopedia handbook of biomaterials and bioengineering, New York Marcel Dekker, 1995, pp. 1015-1054.
17. Nico de Jong and Folkert J. Ten Cate, "New ultrasound contrast agents and technological innovations", Ultrasonics, 1996, pp. 587-590.
18. Wheatley Margaret A, Narayan Padma J, "Hollow polymer microcapsules and method of producing the same". US Patent, No 59 55143, 1999, pp. 9-21.
19. Ling Y H, Xu B, "inhibition of phosphorylation of Histone H1 and H3 Induced By 10-hydroxycamptothecin, DNA topoisomerase in hepatoma cells", Acta Pharm Sci, 1993, pp 546.