Folate and Vitamin B6 Intake and Risk of Colon Cancer in Relation to p53 Expression

Gastroenterology

Volumn 135, Issue 3, 2008, Pages 770-780

  Schernhammer, Eva S ^a,b,c   Ogino, Shuji ^a,d   Fuchs, Charles S ^a,d  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^c Applied Cancer Research Institute for Translational Research Vienna   (Austria)

^d DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CALCIUM; CARBON; CYANOCOBALAMIN; FOLIC ACID; METHIONINE; PARAFFIN; PROTEIN P53; PYRIDOXINE; VITAMIN B COMPLEX;

ADULT; ARTICLE; CANCER RISK; COLON CANCER; DIETARY INTAKE; FEMALE; GENE MUTATION; GENE OVEREXPRESSION; GENETIC HETEROGENEITY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK REDUCTION; VITAMIN SUPPLEMENTATION; COLON TUMOR; DIET; DNA MICROARRAY; DRINKING BEHAVIOR; FOLIC ACID DEFICIENCY; GENETICS; METABOLISM; MIDDLE AGED; PYRIDOXINE DEFICIENCY; RISK FACTOR; TUMOR SUPPRESSOR GENE;

ALCOHOL DRINKING; COLONIC NEOPLASMS; DIET; FEMALE; FOLIC ACID; FOLIC ACID DEFICIENCY; GENES, P53; HUMANS; IMMUNOHISTOCHEMISTRY; METHIONINE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RISK FACTORS; TUMOR SUPPRESSOR PROTEIN P53; VITAMIN B 6; VITAMIN B 6 DEFICIENCY; VITAMIN B COMPLEX;

EID: 51449122122     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2008.06.033     Document Type: Article

References (45)

1. Kim Y.I. Folate, colorectal carcinogenesis, and DNA methylation: lessons from animal studies. Environ Mol Mutagen 44 (2004) 10-25
2. Giovannucci E. Epidemiologic studies of folate and colorectal neoplasia: a review. J Nutr 132 (2002) 2350S-2355S
3. Harnack L., Jacobs Jr. D.R., Nicodemus K., et al. Relationship of folate, vitamin B-6, vitamin B-12, and methionine intake to incidence of colorectal cancers. Nutr Cancer 43 (2002) 152-158
4. Ulrich C.M. Folate and cancer prevention: a closer look at a complex picture. Am J Clin Nutr 86 (2007) 271-273
5. Kim Y.I., Shirwadkar S., Choi S.W., et al. Effects of dietary folate on DNA strand breaks within mutation-prone exons of the p53 gene in rat colon. Gastroenterology 119 (2000) 151-161
6. Crott J.W., Choi S.W., Ordovas J.M., et al. Effects of dietary folate and aging on gene expression in the colonic mucosa of rats: implications for carcinogenesis. Carcinogenesis 25 (2004) 69-76
7. Sohn K.J., Stempak J.M., Reid S., et al. The effect of dietary folate on genomic and p53-specific DNA methylation in rat colon. Carcinogenesis 24 (2003) 81-90
8. Crott J.W., Liu Z., Keyes M.K., et al. Moderate folate depletion modulates the expression of selected genes involved in cell cycle, intracellular signaling and folate uptake in human colonic epithelial cell lines. J Nutr Biochem 19 (2008) 328-335
9. Crott J.W., Liu Z., Choi S.W., et al. Folate depletion in human lymphocytes up-regulates p53 expression despite marked induction of strand breaks in exons 5-8 of the gene. Mutat Res 626 (2007) 171-179
10. Wasson G.R., McGlynn A.P., McNulty H., et al. Global DNA and p53 region-specific hypomethylation in human colonic cells is induced by folate depletion and reversed by folate supplementation. J Nutr 136 (2006) 2748-2753
11. Vogelstein B., Fearon E.R., Hamilton S.R., et al. Genetic alterations during colorectal-tumor development. N Engl J Med 319 (1988) 525-532
12. Baker S.J., Preisinger A.C., Jessup J.M., et al. p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res 50 (1990) 7717-7722
13. Hollstein M., Rice K., Greenblatt M.S., et al. Database of p53 gene somatic mutations in human tumors and cell lines. Nucleic Acids Res 22 (1994) 3551-3555
14. Giovannucci E., Stampfer M.J., Colditz G.A., et al. Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study. Ann Intern Med 129 (1998) 517-524
15. Chen J., Giovannucci E., Hankinson S.E., et al. A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms, and risk of colorectal adenoma. Carcinogenesis 19 (1998) 2129-2132
16. Willett W.C., Sampson L., Stampfer M.J., et al. Reproducibility and validity of a semiquantitative food frequency questionnaire. Am J Epidemiol 122 (1985) 51-65
17. Giovannucci E., Stampfer M.J., Colditz G.A., et al. Folate, methionine, and alcohol intake and risk of colorectal adenoma. J Natl Cancer Inst 85 (1993) 875-884
18. Willett W.C., Sampson L., Browne M.L., et al. The use of a self-administered questionnaire to assess diet four years in the past. Am J Epidemiol 127 (1988) 188-199
19. Willett W.C., Stampfer M.J., Colditz G.A., et al. Moderate alcohol consumption and the risk of breast cancer. N Engl J Med 316 (1987) 1174-1180
20. Stampfer M.J., Willett W.C., Speizer F.E., et al. Test of the National Death Index. Am J Epidemiol 119 (1984) 837-839
21. Melhem M.F., Law J.C., el-Ashmawy L., et al. Assessment of sensitivity and specificity of immunohistochemical staining of p53 in lung and head and neck cancers. Am J Pathol 146 (1995) 1170-1177
22. Nishio M., Koshikawa T., Kuroishi T., et al. Prognostic significance of abnormal p53 accumulation in primary, resected non-small-cell lung cancers. J Clin Oncol 14 (1996) 497-502
23. Greenblatt M.S., Bennett W.P., Hollstein M., et al. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54 (1994) 4855-4878
24. Ogino S., Brahmandam M., Kawasaki T., et al. Combined analysis of COX-2 and p53 expressions reveals synergistic inverse correlations with microsatellite instability and CpG island methylator phenotype in colorectal cancer. Neoplasia 8 (2006) 458-464
25. Camp R.L., Charette L.A., and Rimm D.L. Validation of tissue microarray technology in breast carcinoma. Lab Invest 80 (2000) 1943-1949
26. Ogino S., Kawasaki T., Kirkner G.J., et al. Loss of nuclear p27 (CDKN1B/KIP1) in colorectal cancer is correlated with microsatellite instability and CIMP. Mod Pathol 20 (2007) 15-22
27. Hall P.A., and McCluggage W.G. Assessing p53 in clinical contexts: unlearned lessons and new perspectives. J Pathol 208 (2006) 1-6
28. Ogino S., Brahmandam M., Cantor M., et al. Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component. Mod Pathol 19 (2006) 59-68
29. Curtin K., Slattery M.L., Holubkov R., et al. p53 alterations in colon tumors: a comparison of SSCP/sequencing and immunohistochemistry. Appl Immunohistochem Mol Morphol 12 (2004) 380-386
30. de Jong K.P., Gouw A.S., Peeters P.M., et al. P53 mutation analysis of colorectal liver metastases: relation to actual survival, angiogenic status, and p53 overexpression. Clin Cancer Res 11 (2005) 4067-4073
31. Hu F.B., Stampfer M.J., Rimm E., et al. Dietary fat and coronary heart disease: a comparison of approaches for adjusting for total energy intake and modeling repeated dietary measurements. Am J Epidemiol 149 (1999) 531-540
32. Lunn M., and McNeil D. Applying Cox regression to competing risks. Biometrics 51 (1995) 524-532
33. Glynn R.J., and Rosner B. Comparison of risk factors for the competing risks of coronary heart disease, stroke, and venous thromboembolism. Am J Epidemiol 162 (2005) 975-982
34. Durrleman S., and Simon R. Flexible regression models with cubic splines. Stat Med 8 (1989) 551-561
35. Wei E.K., Giovannucci E., Selhub J., et al. Plasma vitamin B6 and the risk of colorectal cancer and adenoma in women. J Natl Cancer Inst 97 (2005) 684-692
36. Fuchs C.S., Willett W.C., Colditz G.A., et al. The influence of folate and multivitamin use on the familial risk of colon cancer in women. Cancer Epidemiol Biomarkers Prev 11 (2002) 227-234
37. Giovannucci E., Rimm E.B., Ascherio A., et al. Alcohol, low-methionine-low-folate diets, and risk of colon cancer in men. J Natl Cancer Inst 87 (1995) 265-273
38. Ulrich C.M., and Potter J.D. Folate supplementation: too much of a good thing?. Cancer Epidemiol Biomarkers Prev 15 (2006) 189-193
39. Slattery M.L., Curtin K., Ma K., et al. Diet activity, and lifestyle associations with p53 mutations in colon tumors. Cancer Epidemiol Biomarkers Prev 11 (2002) 541-548
40. Lashner B.A., Shapiro B.D., Husain A., et al. Evaluation of the usefulness of testing for p53 mutations in colorectal cancer surveillance for ulcerative colitis. Am J Gastroenterol 94 (1999) 456-462
41. Ulrich C.M., and Potter J.D. Folate and cancer-timing is everything. JAMA 297 (2007) 2408-2409
42. Cole B.F., Baron J.A., Sandler R.S., et al. Folic acid for the prevention of colorectal adenomas: a randomized clinical trial. JAMA 297 (2007) 2351-2359
43. Mason J.B., Dickstein A., Jacques P.F., et al. A temporal association between folic acid fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis. Cancer Epidemiol Biomarkers Prev 16 (2007) 1325-1329
44. Food and Drug Administration. Food standards: amendment of standards of identity ro enriched grain products to require addition of folic acid. Final rule. Fed Register (1996) 8797-8807
45. Ghavam-Nasiri M.R., Rezaei E., Ghafarzadegan K., et al. Expression of p53 in colorectal carcinoma: correlation with clinicopathologic features. Arch Iran Med 10 (2007) 38-42