Factors contributing to the potency of antimicrobial cationic peptides from the N-terminal region of human lactoferrin

FEMS Microbiology Letters

Volumn 239, Issue 2, 2004, Pages 295-299

  Moriarty, Laura C ^a,b   Joannou, Christopher L ^a   Van Den Berg, Jeroen J M ^c   Gorinsky, Beatrice ^b   Evans, Robert W ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF LONDON   (United Kingdom)

^c NUMICO RESEARCH   (Netherlands)

Author keywords

Cationic antimicrobial peptides; Human lactoferrin peptide; Lactoferrin

Indexed keywords

ANTIINFECTIVE AGENT; GLYCINE; LACTOFERRIN; PEPTIDE DERIVATIVE; TRYPTOPHAN;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; SUBSTITUTION REACTION;

ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIA; HUMANS; LACTOFERRIN; MICROBIAL SENSITIVITY TESTS;

EID: 5144230602     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.femsle.2004.08.048     Document Type: Article

References (32)

1. J.H. Brock The physiology of lactoferrin Biochem. Cell Biol. 80 2002 1 6
2. S. Farnaud, and R.W. Evans Lactoferrin - a multifunctional protein with antimicrobial properties Mol. Immunol. 40 2003 395 405
3. J.D. Oram, and B. Reiter Inhibition of bacteria by lactoferrin and other iron-chelating agents Biochim. Biophys. Acta 170 1968 351 365
4. R.R. Arnold, R.M. Cole, and J.R. McGhee A bactericidal effect for human lactoferrin Science 197 1977 263 265
5. J.J. Bullen, H.J. Rogers, and J.E. Lewin The bacteriostatic effect of serum on Pasteurella septica and its abolition by iron compounds Immunology 20 1971 391 406
6. C.A. Bortner, R.D. Miller, and R.R. Arnold Bactericidal effect of lactoferrin on Legionella pneumophila Infect. Immun. 51 1986 373 377
7. J.R. Kalmer, and R.R. Arnold Killing of Actinobacillus actinomycetemcomitans by human lactoferrin Infect. Immun. 56 1988 2552 2557
8. R.T. Ellison III, and T.J. Giehl Killing of Gram-negative bacteria by lactoferrin and lysozyme J. Clin. Inv. 88 1991 1080 1091
9. W. Bellamy, M. Takase, K. Yamauchi, H. Wakabayashi, K. Kawase, and M. Tomita Identification of the bactericidal domain of lactoferrin Biochim. Biophys. Acta 1121 1992 130 136
10. M. Tomita, M. Takase, H. Wakabayashi, and W. Bellamy A review: the active peptide of lactoferrin Adv. Exp. Med. Biol. 357 1994 209 218
11. E.W. Odell, R. Sarra, M. Foxworthy, D.S. Chapple, and R.W. Evans Antibacterial activity of peptides homologous to a loop region in human lactoferrin FEBS Lett. 382 1996 175 178
12. J.H. Kang, M.K. Lee, K.L. Kim, and K.S. Hahan Structure-biological activity relationship of 11-residue highly basic peptide segment of bovine lactoferrin Int. J. Prot. Res. 48 1996 357 363
13. D.S. Chapple, D.J. Mason, C.L. Joannou, E.W. Odell, V. Gant, and R.W. Evans Structure-function relationship of antibacterial synthetic peptides homologous to a helical surface region on human lactoferrin Infect. Immun. 66 1998 2434 2440
14. P.H. Nibbering, E. Ravensbergen, M.M. Welling, L.A. van Berkel, P.H.C. van Berkel, E.K.J. Pauwels, and J.H. Nuijens Human lactoferrin and peptides derived from its N terminus are highly effective against infections with antibiotic-resistant bacteria Infect. Immun. 69 2001 1469 1476
15. R.M. Epand, and H.J. Vogel Diversity of antimicrobial peptides and their mechanisms of action Biochim. Biophys. Acta 1462 1999 11 28
16. R.W.E. Hancock, and D.S. Chapple Peptide antibiotics Antimicrob. Agent. Chemother. 43 1999 1317 1323
17. A. Tossi, L. Sandri, and A. Giangaspero Amphipathic, alpha-helical antimicrobial peptides Biopolymers 55 2000 4 30
18. A. Giangaspero, L. Sandri, and A. Tossi Amphipathic α helical antimicrobial peptides Europ. J. Biochem. 268 2001 5589 5600
19. B.E. Haug, and J.S. Svendsen The role of tryptophan in the antibacterial activity of a 15-residue bovine lactoferricin peptide J. Peptide Sci. 7 2001 190 196
20. H.J. Vogel, D.J. Schibli, W. Jing, E.M. Lohmeier-Vogel, R.F. Epand, and R.M. Epand Towards structure-function analysis of bovine lactoferricin and related tryptophan- and arginine-containing peptides Biochem. Cell Biol. 80 2002 49 63
21. D.J. Schibli, R.F. Epand, H.J. Vogel, and R.M. Epand Tryptophan-rich antimicrobial peptides: comparative properties and membrane interactions Biochem. Cell Biol. 80 2002 667 677
22. W.L. Maloy, and U.P. Kari Structure-activity studies on magainins and other host defense peptides Biopolymers 37 1995 105 122
23. G. Saberwal, and R. Nagaraj Cell-lytic and antibacterial peptides that act by perturbing the barrier function of membranes: facets of their conformational features, structure and function correlations and membrane-perturbing abilities BBA-Rev. Biomembranes 1197 1994 109 131
24. M. Schiffer, C.H. Chang, and F.J. Stevens The functions of tryptophan residues in membrane proteins Protein Eng. 5 1992 213 214
25. C.M. Deber, and N.K. Goto Folding proteins into membranes Nat. Struct. Biol. 3 1996 815 818
26. M. Wu, and R.E.W. Hancock Improved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide Antimicrob. Agents Chemother. 43 1999 1274 1276
27. C. Lawyer, S. Pai, M. Watabe, P. Borgia, T. Mashimo, L. Eagleton, and K. Watabe Antimicrobial activity of a 13 amino acid tryptophan-rich peptide derived from a putative porcine precursor protein of a novel family of antibacterial peptides FEBS Lett. 390 1996 95 98
28. M.E. Selsted, M.J. Novotny, W.L. Morris, Y.-Q. Tang, W. Smith, and J.S.J. Cullor Indolicidin, a novel bactericidal tridecapeptide amide from neutrophils J. Biol. Chem. 267 1992 4292 4295
29. E. Bikshapathy, N. Sitaram, and R. Nagaraj Effect of introducing p-fluorophenylalanine and multiple tryptophan residues in a 13-residue antibacterial peptide Protein Pept. Lett. 6 1999 67 71
30. M. Tomita, M. Takase, W. Bellamy, and S. Shimamura A review: the active peptide of lactoferrin Acta Paediatr. Jap. 36 1994 585 591
31. W.C. Wimley, and S.H. White Experimentally determined hydrophobicity scale of proteins at membrane interfaces Nat. Struct. Biol. 3 1996 815 818
32. M.B. Strøm, O. Rekdal, and J.S. Svendsen Antibacterial activity of 15-residues lactoferricin derivatives J. Peptide Res. 56 2000 265 274