Ethanol palatability and consumption by high ethanol-drinking rats: Manipulation of the opioid system with naltrexone

Behavioral Neuroscience

Volumn 118, Issue 5, 2004, Pages 1089-1096

  Coonfield, Daniel L ^a   Kiefer, Stephen W ^a   Ferraro III, Frank M ^a   Sinclair, John David ^b  

^a KANSAS STATE UNIVERSITY   (United States)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; NALTREXONE; OPIATE RECEPTOR;

ALCOHOL CONSUMPTION; ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AVERSIVE BEHAVIOR; CONTROLLED STUDY; DRINKING BEHAVIOR; LIGHT DARK CYCLE; MALE; NONHUMAN; PALATABILITY; RAT; TASTE;

ALCOHOL DRINKING; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; MALE; NALTREXONE; NARCOTIC ANTAGONISTS; RATS; RECEPTORS, OPIOID;

EID: 5144225286     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/0735-7044.118.5.1089     Document Type: Article

References (56)

1. Apfelbaum, M., & Mandenoff, A. (1981). Naltrexone suppresses hyperphagia induced in the rat by a highly palatable diet. Pharmacology Biochemistry and Behavior, 15, 89-91.
2. Badia-Elder, N. E., & Kiefer, S. W. (1999). Taste reactivity in alcohol-preferring AA and alcohol-avoiding ANA rats. Alcohol, 18, 159-163.
3. Bice, P. J., & Kiefer, S. W. (1990). Taste reactivity in alcohol preferring and nonpreferring rats. Alcoholism: Clinical and Experimental Research, 14, 721-727.
4. 6 subunit. Alcohol, 31, 93-97.
5. Cicero. T. J., (1979). A critique of animal analogs of alcoholism. In E. Majchrowich & E. P. Noble (Eds.), Biochemistry and pharmacology of ethanol (Vol. 2, pp. 533-560). New York: Plenum Press.
6. Coonfield, D. L., Hill, K. G., Kaczmarek, H. J., Ferraro, F. M., III, & Kiefer, S. W. (2002). Low doses of naltrexone reduce palatability and consumption of ethanol in outbred rats. Alcohol, 26, 43-47.
7. Coonfield, D. L., Le, S. X., & Kiefer, S. W. (2000). Naltrexone decreases consumption of sucrose/ethanol solutions in outbred rats [Abstract]. Society for Neuroscience Abstracts, 26, 1039.
8. Cooper, S. J., & Kirkham, T. C. (1990). Basic mechanisms of opioids' effects on eating and drinking. In L. D. Reid (Ed.), Opioids, bulimia, and alcohol abuse & alcoholism (pp. 91-110). New York: Springer-Verlag.
9. Cooper, S. J., & Turkish, S. (1989). Effects of naltrexone on food preference and concurrent behavioral responses in food-deprived rats. Pharmacology Biochemistry and Behavior, 33, 17-20.
10. Davis, V. E., & Walsh, M. J. (1970). Alcohol, amines and alkaloids: A possible biochemical basis for addiction. Science, 167, 1005-1007.
11. deWaele, J.-P., Kiianmaa, K., & Gianoulakis, C. (1995). Distribution of the μ and δ opioid binding sites in the brain of the alcohol-preferring AA and alcohol-avoiding ANA lines of rats. Journal of Pharmacology and Experimental Therapeutics, 275, 518-527.
12. Elder, R. L., Letterman, M., Badia-Elder, N. E., & Kiefer, S. W. (1996). Naltrexone failed to produce a conditioned taste aversion to alcohol [Abstract]. Alcoholism: Clinical and Experimental Research, 20, 58A.
13. Eriksson, K. (1972). Behavioral and physiological differences among rat strains specially selected for their alcohol consumption. In F. A. Seixas, G. S. Omenn, E. D. Burk, & S. Eggleston (Eds.), Annals of the New York Academy of Sciences: Vol. 197. Nature and nurture in alcoholism (pp. 32-41). New York: New York Academy of Sciences.
14. Ferraro, F. M., III, Hill, K. G., Kaczmarek, H. J., Coonfield, D. L., & Kiefer, S. W. (2002). Naltrexone modifies the palatability of basic tastes and alcohol in outbred male rats. Alcohol, 27, 107-114.
15. Froehlich, J. C., Harts, J., Lumeng, L., & Li, T.-K. (1990). Naloxone attenuates voluntary ethanol intake in rats selectively bred for high ethanol preference. Pharmacology Biochemistry and Behavior, 35, 385-390.
16. Gardell, L. R., Hubbell, C. L., & Reid, L. D. (1996). Naltrexone persistently reduces rats' intake of a palatable alcoholic beverage. Alcoholism: Clinical and Experimental Research, 20, 584-588.
17. Gatto, G. J., Murphy, J. M., Waller, M. B., McBride, W. J., Lumeng, L., & Li, T.-K. (1987). Chronic ethanol tolerance through free-choice drinking in the P line of alcohol-preferring rats. Pharmacology Biochemistry and Behavior, 28, 111-115.
18. Grill, H. J., & Berridge, K. C. (1985). Taste reactivity as a measure of the neural control of palatability. Progress in Psychobiology and Physiological Psychology, 11, 1-61.
19. Grill, H. J., & Norgren, R. (1978). The taste reactivity test: I. Mimetic responses to gustatory stimuli in neurologically normal rats. Brain Research, 143, 263-279.
20. A receptors in the acute and chronic effects of ethanol. Psychopharmacology (Berlin), 139, 2-19.
21. Hilakivi, L., Eriksson, C. J. P., Sarviharju, M., & Sinclair, J. D. (1984). Revitalization of the AA and ANA rat lines: Effects on some line characteristics. Alcohol, 1, 71-75.
22. Hill, K. G., & Kiefer, S. W. (1997). Naltrexone treatment increases the aversiveness of alcohol for outbred rats. Alcoholism: Clinical and Experimental Research, 21, 637-641.
23. Hubbell, C. L., Marglin, S. H., Spitalnic, S. J., Abelson, M. L., Wild, K. D., & Reid, L. D. (1991). Opioidergic, serotonergic, and dopaminergic manipulations and rats' intake of a sweetened alcoholic beverage. Alcohol, 8, 355-367.
24. Hyytiä, P., & Sinclair, J. D. (1993). Responding for oral ethanol after naloxone treatment by alcohol-preferring AA rats. Alcoholism: Clinical and Experimental Research, 17, 631-636.
25. Lester, D., & Freed, E. X. (1973). Criteria for an animal model of alcoholism. Pharmacology Biochemistry and Behavior, 1, 103-107.
26. Linseman, M. A., & Harding, S. (1990). Intracerebroventricular morphine enhances alcohol consumption by rats. Pharmacology Biochemistry and Behavior, 36, 405-408.
27. Lumeng, L., Hawkins, D. T., & Li, T.-K. (1977). New strains of rats with alcohol preference and nonpreference. In R. G. Thurman, J. R. Williamson, H. Drott, & B. Chance (Eds.), Alcohol and aldehyde metabolizing systems (pp. 537-544). New York: Academic Press.
28. Lumeng, L., & Li, T.-K. (1986). The development of metabolic tolerance in the alcohol-preferring P rats: Comparison of forced and free-choice drinking of ethanol. Pharmacology Biochemistry and Behavior, 25, 1013-1020.
29. Malila, A. (1978). Intoxicating effects of three aliphatic alcohols and barbital on two rat strains genetically selected for their ethanol intake. Pharmacology Biochemistry and Behavior, 8, 197-201.
30. McBride, W. J., Chernet, E., Guan, X.-M., Lumeng, L., & Li, T.-K. (1990). Densities of opioid receptors in the CNS of alcohol-preferring (P) and non-preferring (NP) lines of rats [Abstract]. Society for Neuroscience Abstracts, 16, 434.
31. Murphy, J. M., Stewart, R. B., Bell, R. L., Badia-Elder, N. E., Carr, L. G., McBride, W. J., et al. (2002). Phenotypic and genotypic characterization of the Indiana university rat lines selectively bred for high and low alcohol preference. Behavior Genetics, 32, 363-388.
32. Nikander, P., & Pekkanen, L. (1977). An inborn alcohol tolerance in alcohol-preferring rats. The lack of relationship between tolerance to ethanol and the brain microsomal (Na+ K+) ATPase activity. Psychopharmacology, 51, 219-223.
33. Olive, M. F., Koenig, H. N., Nannini, M. A., & Hodge, C. W. (2001). Stimulation of endorphin neurotransmission in the nucleus accumbens by ethanol, cocaine, and amphetamine (Rapid Communication 184). Journal of Neuroscience, 21, 1-5. Retrieved from http://www.jneurosci .org
34. O'Malley, S. S., Jaffe, A. J., Rode, S., & Rounsaville, B. J. (1996). Experience of a "slip" among alcoholics treated with naltrexone or placebo. American Journal of Psychiatry, 153, 281-283.
35. Reid, L. D., Gardell, L. R., Chattopadhyay, S., & Hubbell, C. L. (1996). Periodic naltrexone and propensity to take alcoholic beverage. Alcoholism: Clinical and Experimental Research, 20, 1329-1334.
36. Ritz, M. C., George, F. R., & Meisch, R. A. (1989). Ethanol self-administration in ALKO rats: I. Effects of selection and concentration. Alcohol, 6, 227-233.
37. Rusi, M., Eriksson, K., & Maki, J. (1977). Genetic differences in the susceptibility to acute intoxication in selected rats strains. In M. M. Gross (Ed.), Alcohol intoxication and withdrawal (Vol. 3A, pp. 97-109). New York: Plenum Press.
38. Samson, H. H., & Doyle, T. F. (1985). Oral ethanol self-administration in the rat: Effect of naloxone. Pharmacology Biochemistry and Behavior, 22, 91-99.
39. Schuckit, M. A., Mazzanti, C., Smith, T. L., Ahmed, U., Radel, M., Iwata, N., & Goldman, D. (1999). Selective genotyping for the role of 5-HT2A, 5-HT2C, and GABA α6 receptors and the serotonin transporter in the level of response to alcohol: A pilot study. Biological Psychiatry, 45, 647-651.
40. Schwarz-Stevens, K. S., Files, F. J., & Samson, H. H. (1992). Effects of morphine and naloxone on ethanol- and sucrose-reinforced responding in nondeprived rats. Alcoholism: Clinical & Experimental Research, 16, 822-832.
41. Sinclair, J. D. (1990). Drugs to decrease alcohol drinking. Annals of Medicine 22, 357-362.
42. Sinclair, J. D. (2001). Evidence about the use of naltrexone and for different ways of using it in the treatment of alcoholism. Alcohol and Alcoholism, 36, 2-10.
43. Sinclair, J. D., Adkins, J., & Walker, S. (1973, December 14). Morphine-induced suppression of voluntary alcohol drinking in rats. Nature, 246, 425-427.
44. Sinclair, J. D., Le, A. D., & Kiianmaa, K. (1989). The AA and ANA rat lines, selected for differences in voluntary alcohol consumption. Experientia, 45, 798-805.
45. Stewart, R. B., McBride, W. J., Lumeng, L., Li, T.-K., & Murphy, J. M. (1991). Chronic alcohol consumption in alcohol-preferring P rats attenuates subsequent conditioned taste aversion produced by ethanol injections. Psychopharmacology, 105, 530-534.
46. Stromberg, M. F., Meister, S., Volpicelli, J. R., & Ulm, R. R. (1997). Morphine enhances selection of both sucrose and ethanol in a two bottle test. Alcohol, 14, 55-62.
47. Stromberg, M. F., Volpicelli, J. R., & O'Brien, C. P. (1998). Effects of naltrexone administered repeatedly across 30 or 60 days on ethanol consumption using a limited access procedure in the rat. Alcoholism: Clinical and Experimental Research, 22, 2186-2191.
48. Volpicelli, J. R., Ulm, R. R., & Hopson, N. (1991). Alcohol drinking in rats during and following morphine injections. Alcohol, 8, 289-292.
49. Volpicelli, J. R., Watson, N. T., King, A. C., Sherman, C. E., & O'Brien, C. P. (1995). Effect of naltrexone on alcohol "high" in alcoholics. American Journal of Psychiatry, 152, 613-615.
50. Waller, M. B., McBride, W. J., Lumeng, L., & Li, T.-K. (1983). Initial sensitivity and acute tolerance to ethanol in the P and NP lines of rats. Pharmacology Biochemistry and Behavior, 19, 683-686.
51. Wallgren, H., & Barry, H., III. (1970). Voluntary selection of alcohol. In H. Wallgren & H. Barry III (Eds.), Actions of alcohol: Vol. 2. Chronic and clinical aspects (pp. 414-467). New York: Elsevier.
52. Wikler, A. (1976). The theoretical basis of narcotic addiction treatment with narcotic antagonists. In D. Julius & P. Renault (Eds.), Narcotic antagonists: Naltrexone (pp. 119-122). Rockville, MD: National Institute of Drug Abuse.
53. Yeomans, M. R., & Wright, P. (1991). Lower pleasantness of palatable foods in nalmefene-treated human volunteers. Appetite, 16, 249-259.
54. Yeomans, M. R., Wright, P., Macleod, H. A., & Critchley, J. A. (1990). Effects of nalmefene on feeding in humans: Dissociation of hunger and palatability. Psychopharmacology, 100, 426-432.
55. Zhang, M., & Kelley, A. E. (1997). Opiate agonists microinjected into the nucleus accumbens enhance sucrose drinking in rats. Psychopharmacology, 132, 350-360.
56. Zhang, M., & Kelley, A. E. (2000). Enhanced intake of high-fat food following striatal mu-opioid stimulation: Microinjection mapping and fos expression. Neuroscience, 99, 267-277.