AA and ANA rats exhibit the R100Q mutation in the GABAA receptor α6 subunit

Alcohol

Volumn 31, Issue 1-2, 2003, Pages 93-97

  Carr, Lucinda G ^a,d   Spence, John P ^a   Peter Eriksson, C J ^b   Lumeng, Lawrence ^a   Li, Ting Kai ^c  

^a INDIANA UNIVERSITY   (United States)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alcohol preference; GABAA receptor 6 subunit; Polymorphism; Rat lines

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; RECEPTOR SUBUNIT;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRINKING BEHAVIOR; GENE MUTATION; GENETIC VARIABILITY; GENOTYPE; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; RAT STRAIN; SEQUENCE ANALYSIS;

EID: 0242606877     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.alcohol.2003.07.003     Document Type: Article

References (23)

1. Bice P., Foroud T., Bo R., Castelluccio P., Lumeng L., Li T.-K., Carr L.G. Genomic screen for QTLs underlying alcohol consumption in the P and NP rat lines. Mamm Genome. 9:1998;949-955.
2. A receptors. Mol Pharmacol. 63:2003;53-64.
3. Colombo G. Ethanol drinking behaviour in Sardinian alcohol-preferring rats. Alcohol Alcohol. 32:1997;443-453.
4. Colombo G., Agabio R., Lobina C., Reali R., Zocchi A., Fadda F., Gessa G.L. Sardinian alcohol-preferring rats: a genetic animal model of anxiety. Physiol Behav. 57:1995;1181-1185.
5. Crabbe J.C., Belknap J.K., Buck K.J. Genetic animal models of alcohol and drug abuse. Science. 264:1994;1715-1723.
6. DiLella A.G., Woo S.L. Hybridization of genomic DNA to oligonucleotide probes in the presence of tetramethylammonium chloride. Methods Enzymol. 152:1987;447-451.
7. Eriksson K. Ethyl alcohol consumption: valid measurement in albino rats. Science. 161:1968;76-77.
8. Eriksson K. Rat strains specially selected for their voluntary alcohol consumption. Ann Med Exp Biol Fenn. 49:1971;67-72.
9. Fadda F., Mosca E., Colombo G., Gessa G.L. Effect of spontaneous ingestion of ethanol on brain dopamine metabolism. Life Sci. 44:1989;281-287.
10. A receptors in the acute and chronic effects of ethanol. Psychopharmacology (Berl). 139:1998;2-19.
11. Hilakivi L., Eriksson C.J., Sarviharju M., Sinclair J.D. Revitalization of the AA and ANA rat lines: effects on some line characteristics. Alcohol. 1:1984;71-75.
12. 6 subunit. J Neurochem. 67:1996;907-916.
13. A receptor. Nature. 361:1993;356-359.
14. Li T.-K., Lumeng L., Doolittle D.P. Selective breeding of alcohol preference and associated responses. Behav Genet. 23:1993;163-170.
15. Li T.-K., Lumeng L., Doolittle D.P., Carr L.G. Molecular associations of alcohol-seeking behavior in rat lines selectively bred for high and low voluntary ethanol drinking. Alcohol Alcohol Suppl. 1:1991;121-124.
16. Lumeng L., Hawkins D.T., Li T.-K. New strains of rats with alcohol preference and nonpreference. Thurman R.G., Williamson J.R., Drott H., Chance B. Alcohol and Aldehyde Metabolizing Systems. 1977;537-544 Academic Press, New York.
17. Mardones J., Segovia-Riquelme N. Thirty-two years of selection of rats by ethanol preference: UChA and UChB strains. Neurobehav Toxicol Teratol. 5:1983;171-178.
18. 6 receptor subunit may contribute to voluntary aversion to ethanol in the sNP rat line. Brain Res Mol Brain Res. 87:2001;263-270.
19. Salimov R.M., McBride W.J., Sinclair J.D., Lumeng L., Li T.-K. Performance in the cross-maze and slip funnel tests of four pairs of rat lines selectively bred for divergent alcohol drinking behavior. Addict Biol. 1:1996;273-280.
20. Samson H.H., Tolliver G.A., Pfeffer A.O., Sadeghi K.G., Mills F.G. Oral ethanol reinforcement in the rat: effect of the partial inverse benzodiazepine agonist RO15-4513. Pharmacol Biochem Behav. 3:1987;517-519.
21. 6 subunit in Sardinian alcohol non-preferring rats (sNP). Brain Res. 967:2003;98-105.
22. 6 receptors and the serotonin transporter in the level of response to alcohol: a pilot study. Biol Psychiatry. 45:1999;647-651.
23. A receptors and alcohol dependence and the effects of genetic imprinting. Am J Med Genet. 117B:2003;39-45.